Dataset Overview
RBPGEMIN5
Knock-MethodshRNA
RBP FamilyNon-canonical_RBP
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR771QMJ
PlatformHiSeq
Pubmed ID32252787

GEMIN5 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of GEMIN5
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of GEMIN5


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr132372387AC0.00757PTP4A2-FALSE(CA)nSINE,Alu
chr1419686329GA0.00117DUXAP10+FALSE
chr3183861750AC1.09807E-05EIF2B5+FALSE
chr217942775TA0.00367GEN1+FALSE
chr417803537TC0.00366DCAF16-TRUEAluYSINE,Alu
chr642857031AG0.00022RPL7L1+TRUEAluSpSINE,Alu
chr19161668TC0.00456.FALSE
chr237328034TC1.98403E-05.FALSE
chr1144916748CG0.00354NBPF20,PDE4DIP+,-FALSE
chr5132440285CG0.00322HSPA4+FALSE
chr2227662565AC0.00028IRS1-FALSE
chr1100658578GA0.00030DBT-FALSE
chr43242223GA0.00073HTT+FALSE
chr1109475629AG0.00310GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr1173009536TA0.00519.FALSE
chr12133298428AG7.41792E-11PGAM5+TRUEAluSpSINE,Alu
chr352873072AC0.00233TMEM110-MUSTN1,TMEM110-FALSE
chr457326291AG0.00279PAICS+TRUEAluJrSINE,Alu
chr644417142AG0.00144CDC5L+TRUEFLAM_CSINE,Alu
chr7137561078GA0.00558CREB3L2-FALSE(GT)nSINE,Alu
chr2187544223TG0.00254ITGAV+FALSE
chr570248477TA0.00163SMN1,SMN2+FALSEL1MC5aSINE,Alu
chr2025427805AG1.54320E-07GINS1+TRUEAluSzSINE,Alu
chr131905889AG0.00565SERINC2+FALSE
chr132373838TG0.00376PTP4A2-FALSE(T)nSINE,Alu
chr119585519AG6.02134E-06MRTO4+TRUEAluSc8SINE,Alu
chr7158525786GA0.00453ESYT2-FALSE
chr417633798AG0.00053FAM184B-FALSEAluSzSINE,Alu
chr18938276TA0.00178ENO1-FALSE
chr1900720AT0.00204KLHL17+FALSE(TTTA)nSINE,Alu
chr35257981TA3.55991E-06EDEM1+FALSE(ATTTT)nSINE,Alu
chr19644558AG0.00451.FALSEAluSxSINE,Alu
chr1110049203GC0.00530.FALSE
chr153291382AG0.00114ZYG11B+TRUEAluJrSINE,Alu
chr126755643AG0.00428LIN28A+FALSEAluScSINE,Alu
chr347125385GA0.00496SETD2-FALSE
chr3183976477CT0.00215ECE2+FALSE
chr1205687358TC0.00692NUCKS1-FALSE(T)nSINE,Alu
chr122854931CA7.08508E-09ZBTB40+FALSEA-richSINE,Alu
chr342266360TC0.00279TRAK1+FALSE
chr2128620436CT0.00342AMMECR1L-FALSE
chr116889502TC0.00178NBPF1-TRUEL1MC4SINE,Alu
chr116890644CT0.00439NBPF1-FALSE
chr720178562TC1.84789E-06MACC1,LOC101927668-TRUEAluYSINE,Alu
chr312882839CG0.00118RPL32-FALSE
chr255516908AG0.00016CCDC88A-FALSE(GA)nSINE,Alu
chr5130494984AT0.00018HINT1-FALSE
chr3148748197TA0.00026HLTF-FALSE
chr110520715TC0.00119DFFA-TRUEAluSc8SINE,Alu
chr342636141GA0.00224SEC22C,SS18L2+,-FALSE
chr1143399181TG0.00832.FALSE
chr34403260CT0.00603SUMF1-FALSE
chr128661718AG0.00520MED18+TRUEAluSgSINE,Alu
chr237331065TC0.00527.FALSEAluSx1SINE,Alu
chr398518158AT0.00960DCBLD2-FALSE
chr4128758152AG0.00198.FALSEAluSxSINE,Alu
chr2233446265TC0.00177EIF4E2+FALSE
chr138411445GA0.00625INPP5B-FALSE
chr1100489992AG0.00297SLC35A3+TRUEAluSgSINE,Alu
chr349315588TG0.00182USP4-FALSE
chr1206566904TC0.00084SRGAP2+FALSE
chr47761114GA8.00249E-13AFAP1,AFAP1-AS1+,-FALSE
chr110518797TC0.00148.FALSEAluSx1SINE,Alu
chr237330534TC6.35640E-05.FALSEAluSq2SINE,Alu
chr133148736AG0.00849SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr132697085TC0.00366EIF3I+FALSEAluSpSINE,Alu
chr1145513113AG0.00505NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr237327677TC0.00016.FALSE
chr110519912TC0.00942.FALSEAluJrSINE,Alu
chr457326917AG5.41162E-06PAICS+TRUEAluSx1SINE,Alu
chr1184762524TC0.00471FAM129A-TRUEAluSzSINE,Alu
chr16259025CT0.00700RPL22-FALSE
chr147905554CG0.00297FOXD2+FALSE
chr1119184951GA0.00066ZDHHC13+FALSE
chr76501833AT0.00032KDELR2-FALSE
chr626095484AG0.00231.FALSEAluYSINE,Alu
chr192976590GA0.00768EVI5-FALSE
chr124086794GT0.00309TCEB3+FALSE(T)nSINE,Alu
chr116918783CT0.00252NBPF1-FALSE
chr1144594170CT0.00636NBPF20+FALSE
chr1145693958AG3.55543E-06NBPF20,NBPF10+TRUEAluSzSINE,Alu
chr199672943TC1.63385E-06.FALSEAluSx3SINE,Alu
chr3156258295TC0.00096SSR3-TRUEAluYk3SINE,Alu
chr120980225GT0.00055DDOST-FALSE
chr373115786TC3.88619E-05PPP4R2+FALSE
chr417803673TC0.00206DCAF16-TRUEAluYSINE,Alu
chr9136209399AT0.00011MED22-FALSE
chr254888359AG3.08576E-05SPTBN1+FALSE
chr1144606996GC0.00107NBPF20+FALSE
chr1292537702TA0.00368BTG1-FALSE
chr147767914GA0.00061STIL-FALSE
chr128661767AG0.00144MED18+TRUEAluSgSINE,Alu
chr1226259212CA0.00167H3F3AP4,H3F3A+FALSE
chr921863618TC0.00148MTAP+FALSEAluYSINE,Alu
chr110520178TC0.00112.FALSEAluSxSINE,Alu
chr919373160AG0.00404DENND4C+FALSEMADE1SINE,Alu
chr1114940210TG0.00028TRIM33-FALSE(T)nSINE,Alu
chr110520117TC0.00078.FALSEAluSxSINE,Alu
chr46676407GC0.00178LOC93622+FALSE
chr146164493TC0.00325IPP-TRUEAluJbSINE,Alu
chr120826786TA0.00030MUL1-FALSE
chr1475202372AG8.84130E-05FCF1+TRUEAluScSINE,Alu
chr1610625050TC1.54421E-05EMP2-TRUEAluSx3SINE,Alu
chr2217498311TC0.00977IGFBP2+FALSE(CCG)nSINE,Alu
chr456295166AG0.00988CLOCK-FALSE
chr126755209AG0.00745LIN28A+FALSEAluSx1SINE,Alu
chr1075009781TC9.15447E-06DNAJC9-AS1,MRPS16+,-FALSEAluYSINE,Alu
chr133148214AG0.00734SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr2043707842AG0.00100STK4+TRUEAluJbSINE,Alu
chr5149829075AG0.00277RPS14-FALSE
chr18413317AC0.00957RERE-FALSE
chr1205686520AG0.00980NUCKS1-FALSE
chr9140174976GT0.00045TOR4A+FALSE
chr4100869246TC0.00444H2AFZ-FALSE
chr124289896TG0.00051PNRC2+FALSE
chr111084103TA0.00162TARDBP+FALSE
chr642856924AG2.08684E-05RPL7L1+TRUEAluSpSINE,Alu
chr1762109CT0.00026LINC00115-FALSE
chr314986110TC1.11022E-16FGD5-AS1-TRUEFLAM_CSINE,Alu
chr116112795AG0.00106FBLIM1+FALSE
chr534908535TC0.00054RAD1-FALSEAluSpSINE,Alu
chr138327700TC0.00132INPP5B-TRUEAluSx3SINE,Alu
chr1179044110AG0.00931FAM20B+TRUEAluSxSINE,Alu
chr116576295GA0.00231FBXO42-FALSEA-richSINE,Alu
chr1144828845AT0.00178NBPF20,NBPF9+FALSE
chr12125512507AG0.00276.FALSEAluYSINE,Alu
chr19163096TC0.00185.FALSEFRAMSINE,Alu
chr246414708GA0.00155PRKCE+FALSE
chr1179044181AG0.00660FAM20B+TRUEAluSxSINE,Alu
chr1145369556AG0.00061NBPF20,NBPF10+TRUEL1MC4SINE,Alu
chr4761932GA0.00827PCGF3+FALSE
chr626368938CT0.00121BTN3A2+FALSE
chr1148003749TC0.00517NBPF8-TRUEL1MC4SINE,Alu
chr128825418AG0.00961PHACTR4+TRUEAluSgSINE,Alu
chr6149912555GA0.00551.FALSE
chr142644770CT1.21495E-06FOXJ3-FALSE
chr133071159AG0.00947ZBTB8A+TRUEAluSx1SINE,Alu
chr985861561CT0.00287FRMD3-FALSE(TC)nSINE,Alu
chr175230606CT0.00077TYW3+FALSE
chr1666923393AG0.00228PDP2+TRUEAluSzSINE,Alu
chr1109535128GA0.00063WDR47-FALSE
chr126143697GC0.00778SEPN1+FALSE
chr1116237273AG0.00814VANGL1+FALSE
chr3141667690TC0.00018TFDP2-TRUEAluYSINE,Alu
chr11769889TC0.00211PDDC1-TRUEAluYSINE,Alu
chr1113672616AG0.00450.FALSEAluJbSINE,Alu
chr8128752685GA2.94991E-09MYC+FALSE
chr2128949255AG0.00063UGGT1+TRUEAluSgSINE,Alu
chrX54587297AG0.00759GNL3L+TRUEAluSq2SINE,Alu
chr19328242AG0.00116H6PD+TRUEAluJrSINE,Alu
chr2025428750AG3.17139E-06GINS1+TRUEAluJbSINE,Alu
chr119586501AG5.42567E-10MRTO4+TRUEAluSzSINE,Alu
chr348787042TC1.97898E-05PRKAR2A-TRUEAluSx3SINE,Alu
chrX118673382TC0.00021CXorf56-TRUEAluSzSINE,Alu
chr136535560AG0.00059.FALSEAluSx1SINE,Alu
chr315113893TC0.00042RBSN-TRUEAluSz6SINE,Alu
chr11164179GA0.00983SDF4-FALSEG-richSINE,Alu
chr1153533586TC0.00358S100A2-FALSECharlie18aSINE,Alu
chr136067677TC0.00462PSMB2-TRUEAluSzSINE,Alu
chr1549283066TG0.00065SECISBP2L-FALSE
chr642856917AG0.00280RPL7L1+TRUEAluSpSINE,Alu
chr5178293266GA0.00924ZNF354B+FALSE
chr116932428CG0.00197NBPF1-FALSEL1MC2SINE,Alu
chr417803604TC0.00206DCAF16-TRUEAluYSINE,Alu
chr123833607AT0.00818E2F2-FALSE
chr1252710715GA0.00729KRT83-FALSE
chr19642828TA0.00148SLC25A33+FALSE
chr5177577353CA0.00121NHP2-FALSE
chr457326291AG0.00017PAICS+TRUEAluJrSINE,Alu
chr115736752GA0.00170EFHD2+FALSE
chr1203709034AG0.00049ATP2B4+FALSE
chr1117530273AG0.00270PTGFRN+FALSE
chr116890320TC0.00045NBPF1-FALSE
chr579923293TC0.00039DHFR-TRUEAluJrSINE,Alu
chr1145112414TC0.00079NBPF20,SEC22B+FALSE
chr3128338880TA0.00828RPN1-FALSE
chr5147793406AG0.00323FBXO38+FALSE
chr1742880190TC0.00284GJC1-TRUEAluJbSINE,Alu
chr11133689GA0.00856.FALSEAluJbSINE,Alu
chr11622754AG0.00221CDK11B,SLC35E2B-FALSEMLT1F2SINE,Alu
chr110517653TC1.73226E-05.FALSEAluSx1SINE,Alu
chr1220231982TC0.00328RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr1114940230TG0.00413TRIM33-FALSE(T)nSINE,Alu
chr236704033TA0.00012CRIM1+FALSE
chr398620372GA3.94317E-05DCBLD2-FALSE
chr2216148871TG0.00071.FALSETigger1SINE,Alu
chr125894467AT0.00136LDLRAP1+FALSEMIRbSINE,Alu
chr274332839AG4.77205E-06TET3+FALSE
chr9124103030GA0.00193STOM-FALSEAluSq2SINE,Alu
chr1109535116GA0.00013WDR47-FALSE
chr133149502AG0.00045SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr425278988TC2.09007E-08PI4K2B+FALSE
chr1207942456AG0.00322CD46+TRUEAluSg4SINE,Alu
chr2203741640TC0.00419.FALSEAluJrSINE,Alu
chr146521559AT0.00177PIK3R3-FALSE
chr1162497739GC0.00138UHMK1+FALSE
chr136067833TC3.75622E-05PSMB2-TRUEAluSzSINE,Alu
chr136067749TC0.00748PSMB2-TRUEAluSzSINE,Alu
chr297884961GA0.00668ANKRD36+FALSE
chr1144828765AT0.00976NBPF20,NBPF9+FALSE
chr1779514129GA0.00164FAAP100-FALSE
chr274090064AT0.00197STAMBP+FALSE
chr315112631AG0.00019RBSN-FALSE
chr1542824348AG0.00685SNAP23+TRUEAluSgSINE,Alu
chr1165877666TC0.00327UCK2+FALSE(T)nSINE,Alu
chr7107789927TC0.00111NRCAM-FALSE
chr373024350CA0.00109GXYLT2+FALSE
chr3156258230TC0.00011SSR3-TRUEAluYk3SINE,Alu
chr11650845GA0.00094CDK11B,CDK11A-FALSE
chr7937828GA0.00605ADAP1-FALSE
chr543575009TC0.00498NNT-AS1-TRUEAluSq2SINE,Alu
chr674133990TC0.00201.FALSEAluYSINE,Alu
chr744918804TC0.00015PURB-TRUEAluSgSINE,Alu
chr237330172TG0.00972.FALSE
chr128930023GA0.00037TAF12-FALSE
chr2174086933CA0.00457ZAK,MLK7-AS1+,-FALSEAluJoSINE,Alu
chr175336210TC0.00868RPAIN,C1QBP+,-FALSE
chr238522643GT0.00285ATL2-FALSE
chr133139178AG0.00108RBBP4+TRUEAluSx3SINE,Alu
chr3197611048AG0.00573.FALSEAluSx1SINE,Alu
chr1120163007GA0.00573ZNF697-FALSE
chr827661063TA0.00138ESCO2+FALSE(AC)nSINE,Alu
chrX123046302AG0.00649XIAP+TRUEAluJbSINE,Alu
chr248605828TA0.00650FOXN2+FALSE(T)nSINE,Alu
chr117320251GA0.00367ATP13A2-FALSE
chr123409538GA0.00292KDM1A+FALSE
chr1186332550AT0.00328TPR-FALSE
chr1474431191AG0.00670ENTPD5-FALSE
chr126144433TC0.00476SEPN1+FALSE
chr2218572729AG0.00228PEX26+TRUEAluYf1SINE,Alu
chr373025345AG0.00219.FALSEAluSzSINE,Alu
chr1256510702TC0.00052RPL41+FALSE
chr193465142TC0.00100NFIC+FALSE
chr8145159709CA0.00314MAF1+FALSE
chr2174773510TA0.00775SP3-FALSEA-richSINE,Alu
chr5151041883GA0.00343SPARC-FALSE
chr1911256672TC9.28647E-11SPC24-TRUEAluJr4SINE,Alu
chr59546451GA0.00030SNHG18+FALSE
chr275882576TC0.00328MRPL19+FALSE
chr642854580AG0.00330RPL7L1+TRUEAluScSINE,Alu
chr3178954055TC0.00308PIK3CA+FALSE
chr237331065TC0.00293.FALSEAluSx1SINE,Alu
chr1151778899TC0.00475RORC-FALSE
chr919376250AT0.00706.FALSE
chr1470838324TC0.00011SYNJ2BP-COX16,SYNJ2BP-TRUEAluSgSINE,Alu
chr310193358AG0.00317VHL+TRUEL1ME4aSINE,Alu
chr349067295CA0.00740QRICH1-FALSE
chr127202789TC0.00026.FALSEAluSq2SINE,Alu
chr167874689TC0.00338SERBP1-TRUEAluSx3SINE,Alu
chr1765335454TC9.75664E-07PSMD12-TRUEAluSxSINE,Alu
chr237327685TC0.00057.FALSE
chr356654248TG3.99921E-06CCDC66,FAM208A+,-FALSE
chr540826638CA0.00749LOC100506548-FALSELTR78SINE,Alu
chr110520099TC0.00152.FALSEAluSxSINE,Alu
chr19162394TC0.00072.FALSEAluSxSINE,Alu
chr1118066459AG0.00496MAN1A2+FALSE
chr237328087TC0.00313.FALSE
chr122852880GC0.00247ZBTB40+FALSE
chr75410425GC0.00043TNRC18-FALSE(CACCGC)nSINE,Alu
chr111814631AG5.11326E-05.FALSE
chr111783106AG0.00022.FALSEAluSxSINE,Alu
chr2232328545CT0.00581NCL-FALSE
chr3141668758TC2.84489E-05TFDP2-TRUEAluSzSINE,Alu
chr1958361328GC0.00972ZNF587+FALSE
chr5122359502AC0.00707PPIC-FALSE(AC)nSINE,Alu
chr1565249466AG2.07949E-05ANKDD1A+TRUEAluSz6SINE,Alu
chr154691921GA0.00032SSBP3-FALSE
chr110519064TC0.00012.FALSEAluSx3SINE,Alu
chr11125763746CG0.00166HYLS1,PUS3+,-FALSE
chr146764013GA0.00224LRRC41-FALSE
chr237328042TC6.80414E-06.FALSE
chr1144931330CT0.00479NBPF20,PDE4DIP+,-FALSE
chr2158636910GA0.00160ACVR1-FALSE
chr6166824702CT0.00587RPS6KA2-FALSE(T)nSINE,Alu
chr140539201AG0.00028PPT1-FALSE
chr1145441843GA0.00744NBPF20,NBPF10,TXNIP+FALSE
chr136067925TC1.59250E-07PSMB2-TRUEAluSzSINE,Alu
chr1145512078AG0.00099NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr2176042871AT0.00204ATP5G3-FALSE
chr1220231959TC2.75997E-05RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr2204055454TC0.00293NBEAL1+FALSE
chr42940265TC4.71601E-06NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr3155658362CT0.00807.FALSEMIR3SINE,Alu
chr439550978TC0.00558UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr1145511993AG0.00088NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr366430372TA0.00300LRIG1-FALSE
chr310192652AG0.00155VHL+TRUEAluSx1SINE,Alu

Differential Expression Gene Analysis