Dataset Overview
RBPNFX1
Knock-MethodshRNA
RBP FamilyR3H
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR007XKL
PlatformHiSeq
Pubmed ID32252787

NFX1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of NFX1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of NFX1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr837351214TC0.00109LINC01605-FALSE
chr286249930TC0.00269LOC90784-TRUEAluJrSINE,Alu
chr1160965379TC0.00477F11R-TRUEAluScSINE,Alu
chr237329214TC0.00081.FALSEAluJr4SINE,Alu
chr1161932324AG0.00356ATF6+FALSE
chr333138549GA0.00612GLB1-FALSE
chr823049112TC0.00774TNFRSF10A-TRUE
chr11118621699TC0.00108DDX6-FALSE
chr261416407GT0.00041USP34-FALSEAluSc8SINE,Alu
chr133149443AG6.55200E-05SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr146075612AG0.00153NASP+TRUEAluSx4SINE,Alu
chr1475202288CT0.00706FCF1+FALSEAluScSINE,Alu
chr122854931CA7.08508E-09ZBTB40+FALSEA-richSINE,Alu
chr729960211CA0.00034SCRN1-FALSE
chr1226333561AG0.00373ACBD3-FALSE
chr120976163CT0.00174PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr191486839TC0.00329ZNF644-FALSE
chr717384818AG0.00241AHR+TRUEAluScSINE,Alu
chr5149823799AT0.00672RPS14-FALSE
chr1205687358TC0.00432NUCKS1-FALSE(T)nSINE,Alu
chr153289790CT0.00281ZYG11B+FALSEAluSzSINE,Alu
chr192862826AG0.00100.FALSEAluJrSINE,Alu
chr1150281017AG0.00057MRPS21+TRUEAluSzSINE,Alu
chr417802819TC0.00747DCAF16-TRUEAluSzSINE,Alu
chr417488244GA0.00030QDPR-FALSE
chr1202992954TC0.00042TMEM183A+FALSE
chr1150446673AG2.11627E-07RPRD2+FALSE
chr5137754695TC0.00266KDM3B+FALSE
chr285837797TC0.00050USP39,C2orf68+,-FALSEAluSxSINE,Alu
chr19163319TC0.00936.FALSEAluSpSINE,Alu
chr2018468633CA3.51877E-10RBBP9-FALSE
chr3128215735GA0.00734GATA2-AS1+FALSE
chr579923912TC0.00037DHFR-TRUEAluSpSINE,Alu
chr136067760TC0.00258PSMB2-TRUEAluSzSINE,Alu
chr6111591610AG0.00105.FALSEFLAM_ASINE,Alu
chr517276080AC0.00298BASP1+FALSE(TC)nSINE,Alu
chr193827764AG0.00056DR1+FALSE
chr1540954864AG0.00636KNL1+TRUE
chr287883323AG0.00910.FALSE
chr564964627TC2.01273E-05SGTB-TRUEAluSx1SINE,Alu
chr76063467GA0.00620EIF2AK1-FALSE
chr1206566195CT0.00462SRGAP2+FALSE
chr2201842323TC0.00390FAM126B-TRUEAluJbSINE,Alu
chr1101444071GA0.00963SLC30A7+FALSEMIR3SINE,Alu
chr133148691AG2.12433E-06SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr29630248GT0.00764ADAM17-FALSE
chr1145688664AT0.00298NBPF20,NBPF10,RNF115+FALSE
chr116933629AG0.00310NBPF1-FALSEGA-richSINE,Alu
chr13546137AC0.00778TPRG1L+FALSEAluSzSINE,Alu
chr4123859284CT0.00034SPATA5+FALSE
chr1197070776CT0.00698ASPM-FALSE
chr2206983115TC0.00992.FALSEAluJbSINE,Alu
chr2232319593AC0.00348NCL-FALSEA-richSINE,Alu
chr127338911CT0.00455FAM46B-FALSE
chr136752811CT2.19602E-12THRAP3+FALSE
chr246612340GT3.13955E-05EPAS1+FALSE
chr5180663939CA0.00522RACK1-FALSE
chr1144922523CT0.00566NBPF20,PDE4DIP+,-FALSE
chr3121351277AT0.00388HCLS1-FALSE
chr1942375584AG0.00021.FALSEAluSxSINE,Alu
chr152520866CT0.00108TXNDC12-FALSE
chr2218572742AG8.48972E-05PEX26+TRUEAluYf1SINE,Alu
chr41066073TA0.00387RNF212-FALSEL1MC1SINE,Alu
chr1144822920AT0.00040NBPF20,NBPF9+FALSE
chr6160211652CG0.00719MRPL18+FALSE
chr5157184013AG0.00631LSM11+TRUEAluYSINE,Alu
chr1118071289AG0.00023.FALSE
chr643747963GC0.00274VEGFA+FALSE
chr136530674AG0.00603.FALSEAluSgSINE,Alu
chr136024788CT5.60663E-14NCDN+FALSE
chr5132028864GA0.00593KIF3A-FALSE
chr1223967953CT0.00341TP53BP2-FALSE
chr3196079305TC0.00161.FALSEAluSxSINE,Alu
chr152882970AG0.00533PRPF38A+FALSE
chr145975345AG0.00127MMACHC+TRUEAluSg7SINE,Alu
chr286251151TC0.00763.FALSEAluSxSINE,Alu
chr11594977TC0.00749CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr1205737665GT0.00025RAB29-FALSEAluSq2SINE,Alu
chr119578576GA0.00347MRTO4+FALSE
chr153288897AG0.00439ZYG11B+TRUEAluJoSINE,Alu
chr1109475572AG0.00170GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr2232325426AT0.00547NCL-FALSE(TCA)nSINE,Alu
chr1757281060AG0.00026PRR11+TRUEAluSzSINE,Alu
chr16704652CT1.57063E-06DNAJC11-FALSE
chr264863970CT9.52027E-09SERTAD2-FALSE
chr186049362CA0.00140CYR61+FALSE
chr1200558363TC1.35174E-05KIF14-FALSE
chr1194863488CT0.00615ENDOD1+FALSE
chr8101269589AT0.00281RNF19A-FALSE
chr29629298GC0.00590ADAM17-FALSE(TGT)nSINE,Alu
chr1119184951GA0.00066ZDHHC13+FALSE
chr146269493GC0.00233MAST2+FALSE
chr1201438097GC2.75480E-05PHLDA3-FALSE
chr333185036GA0.00573CRTAP+FALSEL2aSINE,Alu
chr120826786TA0.00030MUL1-FALSE
chr468483804AT0.00720UBA6-FALSE
chr830643547TA0.00748PPP2CB-FALSE
chr234080819AC0.00815LINC01317+FALSEMSTDSINE,Alu
chr2208619699AG0.00741CCNYL1+TRUEAluJbSINE,Alu
chr116841561GA0.00025.FALSE
chr296915238TC0.00510.FALSEAluJrSINE,Alu
chr12125513906CA0.00464.FALSEAluSx1SINE,Alu
chr152378211TC0.00195RAB3B-TRUEFLAM_CSINE,Alu
chr8145159718GC0.00409MAF1+FALSE
chr2206987634TC0.00281.FALSEAluJbSINE,Alu
chr2191799595AG0.00162GLS+FALSE
chr1168218543AG0.00547.FALSEAluSzSINE,Alu
chr738764464TC0.00193VPS41-TRUEAluSpSINE,Alu
chr315114395TC0.00333RBSN-TRUEAluYSINE,Alu
chr1179829093TC0.00056TOR1AIP2-TRUEAluJrSINE,Alu
chr3194789663TC0.00754XXYLT1-FALSEMARNASINE,Alu
chr1061548859AC0.00011CCDC6-FALSE
chr274690039GA0.00412MOGS-FALSE
chr9115446668TC1.81109E-05INIP-TRUEAluJrSINE,Alu
chr146159809TA0.00605TMEM69+FALSE
chr47764131AT5.82585E-11AFAP1,AFAP1-AS1+,-FALSE
chr261369774TC0.00267LOC339803-TRUEAluSxSINE,Alu
chr1450361197GT1.76251E-06ARF6+FALSE
chr2173461888AG0.00110PDK1+TRUEAluJrSINE,Alu
chr152306075TC8.71211E-05NRDC-FALSE(TCA)nSINE,Alu
chr312624763TC1.62214E-06MKRN2+FALSE
chr717384437AG0.00192AHR+TRUEAluSxSINE,Alu
chr2203741032TC0.00282.FALSEAluJrSINE,Alu
chr250148477CT0.00741NRXN1-FALSE
chr642856330AG2.22045E-16RPL7L1+TRUE
chr116891365GA0.00475NBPF1-FALSE
chr237328082TC1.18454E-08.FALSE
chr119542250TC0.00859LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1062554474TG6.65730E-05CDK1+FALSE
chr4152020780CT0.00925RPS3A+FALSE
chr1675479250TC0.00568TMEM170A-TRUEAluJbSINE,Alu
chr229023124GT0.00477PPP1CB+FALSE
chr596110544TC0.00295ERAP1-TRUE
chr1269158881AG0.00219SLC35E3+TRUEAluSpSINE,Alu
chr3194369580CA0.00042LSG1-FALSE
chr1942375585AG0.00022.FALSEAluSxSINE,Alu
chr1138156GT0.00177LOC729737-FALSE
chr410099340TC0.00000WDR1-FALSE
chr125894467AT0.00136LDLRAP1+FALSEMIRbSINE,Alu
chr25837878GA7.66453E-07SOX11+FALSE
chr1150939883AG0.00472CERS2-FALSE
chr1262928633GA0.00307MON2+FALSE
chr228639641CG0.00431.FALSE
chr126608015TA3.80922E-07.FALSE
chr136067784TC0.00821PSMB2-TRUEAluSzSINE,Alu
chr145975628AG0.00465MMACHC+TRUEAluSx4SINE,Alu
chr233046027GC0.00397TTC27+FALSE
chr116841620TA0.00023.FALSE
chr1475202287TC0.00757FCF1+FALSEAluScSINE,Alu
chr9132268259AG0.00032LINC00963+TRUEAluJbSINE,Alu
chr237328075TC0.00335.FALSE
chr2232319615AT8.19218E-06NCL-FALSE
chr3160968914TC0.00305NMD3+FALSE
chr629912348AG0.00429.FALSE
chr3125033835TG0.00385ZNF148-FALSEAluJbSINE,Alu
chr671298815TA0.00287.FALSE
chr128823671TC0.00073PHACTR4+FALSE
chr1774560728AG0.00510SNHG16+FALSETHE1BSINE,Alu
chr145987539CA0.00660PRDX1-FALSE
chr128661576AG0.00625MED18+TRUEAluSgSINE,Alu
chr127861184GT0.00425AHDC1-FALSE(TCTTTT)nSINE,Alu
chr63154871AC7.50591E-06TUBB2A-FALSE
chr1114940211GT8.00129E-05TRIM33-FALSE(T)nSINE,Alu
chr3186502665CT0.00637EIF4A2+FALSE
chr457801150AT0.00462REST+FALSE
chr124289057GC0.00044PNRC2+FALSE
chr184373309TC0.00627TTLL7-FALSE
chr1829410068CT0.00807TRAPPC8-FALSE
chr12335348CT0.00018RER1+FALSE
chr119201928CT0.00149ALDH4A1-FALSE
chr314986471TC3.70393E-05FGD5-AS1-TRUEAluSq2SINE,Alu
chr237331116TC0.00481.FALSEAluSx1SINE,Alu
chr2196999051CG0.00403STK17B-FALSEMER1BSINE,Alu
chr168167935AG0.00390GNG12-FALSE
chr1918476206AG0.00156PGPEP1+TRUEAluJbSINE,Alu
chr7100860467CG0.00267PLOD3-FALSE
chr1742225547AC0.00240C17orf53+FALSE
chr353259329GC0.00036TKT-FALSE
chr2035520976TC0.00254TLDC2,SAMHD1+,-FALSEFLAM_ASINE,Alu
chr7157129834CG1.26796E-05DNAJB6+FALSE
chr2178406765TA0.00325AGPS+FALSE
chr110520154TC0.00124.FALSEAluSxSINE,Alu
chr1571124666CA4.50846E-10LARP6-FALSE
chr116932845TG0.00732NBPF1-FALSEL1MC2SINE,Alu
chr1109513497CT0.00186WDR47-FALSE
chr1767539228GC0.00200.FALSE
chr2101587455CT0.00178NPAS2+FALSE
chr9124094999GT0.00764GSN+FALSE(TG)nSINE,Alu
chr822111410AG0.00396.FALSEAluSzSINE,Alu
chr2233446266CT0.00177EIF4E2+FALSE
chr16683581AC0.00189PHF13+FALSE
chr1610623553TC0.00024EMP2-TRUEAluSpSINE,Alu
chrX77083538TC0.00055MAGT1-TRUEAluSz6SINE,Alu
chr19328213AG5.00055E-05H6PD+TRUEAluJrSINE,Alu
chr165147002CT6.62669E-07CACHD1+FALSE
chr1207247475CA0.00680PFKFB2+FALSEMER5BSINE,Alu
chr10104417856TA0.00616TRIM8+FALSE(AAT)nSINE,Alu
chr167874689TC1.54545E-05SERBP1-TRUEAluSx3SINE,Alu
chr2036147563TC0.00313BLCAP-TRUE
chr1186390303AC0.00455C1orf27+FALSEL1ME3FSINE,Alu
chr339452772AG0.00127RPSA+FALSE
chr2231375020TA0.00990TUG1+FALSE
chr16259433GA0.00493RPL22-FALSEG-richSINE,Alu
chr1760522252GA0.00187METTL2A+FALSE
chr1591044380GC0.00453IQGAP1+FALSE
chr353260620TG0.00069TKT-FALSE
chr1150704633TC1.58455E-05CTSS-TRUEAluJoSINE,Alu
chr286249961TC0.00262LOC90784-TRUEAluJrSINE,Alu
chr1220231455TC0.00274RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr126774224AG0.00349DHDDS+TRUEAluSz6SINE,Alu
chr838829416AG0.00695PLEKHA2+TRUEAluYcSINE,Alu
chr484525985TG0.00041GPAT3+FALSE(TTGTT)nSINE,Alu
chr1155161702GC0.00020MUC1-FALSE
chr133149414AG0.00990SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr72278515TC0.00937MRM2-TRUEAluSx1SINE,Alu
chr143629982CT0.00733EBNA1BP2-FALSE
chr572801323CA0.00119BTF3+FALSE
chr46925237CG0.00870TBC1D14+FALSE
chr72394991CT9.93448E-08EIF3B+FALSE
chr186986259GA5.32960E-05LAMA1-FALSE
chr125893927AG0.00081LDLRAP1+FALSE
chr2238253065CT0.00914COL6A3-FALSE
chr2112252628GT7.26456E-05MIR4435-2HG-FALSE
chr127992800CA5.71645E-05IFI6-FALSEFAMSINE,Alu
chr1244572645TG0.00103ADSS-FALSE
chr2204162597AG0.00296CYP20A1+TRUEAluSxSINE,Alu
chr1063852210CT0.00324ARID5B+FALSE
chr1072648336CT0.00461PCBD1-FALSE(GGCCG)nSINE,Alu
chr126801762GT0.00762HMGN2+FALSE
chr1151374016AG0.00822PSMB4+FALSE
chr438946824CT0.00250FAM114A1+FALSE
chr38922054TC0.00464RAD18-FALSE
chr345721934AG0.00011LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr110520902AT0.00032DFFA-FALSE
chr1155161736GA0.00088MUC1-FALSE
chr315113736TC0.00641RBSN-TRUEAluSz6SINE,Alu
chr110517691TC0.00558.FALSEAluSx1SINE,Alu
chr71199790GC0.00049ZFAND2A-FALSE
chr124296869GT0.00505.FALSEAluSgSINE,Alu
chr315113893TC0.00042RBSN-TRUEAluSz6SINE,Alu
chr237330146CG2.68632E-05.FALSE
chr642856905AG4.80826E-12RPL7L1+TRUEAluSpSINE,Alu
chr146075171AC0.00140NASP+FALSEA-richSINE,Alu
chr189225976TC0.00586PKN2+FALSE
chr12125627187CT0.00055AACS+FALSE
chr3119212015GA0.00024POGLUT1+FALSE
chr1591044383GT0.00440IQGAP1+FALSE
chr120976075TC0.00135PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr1051026705CG0.00456PARG-FALSE
chr1155214017CA0.00946GBA-FALSEAluSx3SINE,Alu
chr312641718GA0.00091RAF1-FALSE
chr540830064TC0.00554.FALSEAluSpSINE,Alu
chr1144851999AC0.00385NBPF20,PDE4DIP+,-FALSE
chr1911256703TC2.95254E-05SPC24-TRUEAluJr4SINE,Alu
chr3172351006CG6.14326E-06NCEH1-FALSE
chr132687475TC0.00785TMEM234,EIF3I+,-FALSE
chr349460407CT0.00080NICN1-FALSEL2cSINE,Alu
chr140538317CA0.00178CAP1+FALSE
chr116893686GC0.00386NBPF1-FALSE
chr11419768AG0.00189ATAD3B+TRUEAluYk2SINE,Alu
chr1148556790TA0.00728.FALSE
chr19160963TC0.00130.FALSEAluJbSINE,Alu
chr16659505GA0.00405KLHL21-FALSE
chr120976163CT0.00091PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr119585903GA0.00575MRTO4+FALSEAluJrSINE,Alu
chr540832553AT9.00390E-07RPL37-FALSE
chr3195436334AG0.00017LINC00969+TRUEAluJrSINE,Alu
chr210076828AG0.00026.FALSEAluJrSINE,Alu
chr232535746AG0.00085.FALSEAluJbSINE,Alu
chr1236748403GC0.00519HEATR1-FALSE
chr720177519TC0.00885MACC1,LOC101927668-TRUEAluSxSINE,Alu
chr1204521616AG4.81420E-06MDM4+TRUEAluSgSINE,Alu
chr145244053AG0.00202RPS8+FALSE
chr199673275TC0.00081.FALSETigger1SINE,Alu
chr3183209035TC9.98912E-07KLHL6-TRUEAluSqSINE,Alu
chr42940243TA0.00028NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr1475202372AG8.84130E-05FCF1+TRUEAluScSINE,Alu
chr119586455AG0.00772MRTO4+TRUEAluSzSINE,Alu
chr2151326173AC0.00143RND3-FALSE
chr131905905GC0.00948SERINC2+FALSE
chr122854702CT4.66415E-11ZBTB40+FALSE
chr766105198CA0.00456KCTD7+FALSE
chr1942376711AG0.00223.FALSEAluSpSINE,Alu
chr265496187GA0.00103ACTR2+FALSE
chr128573293GA0.00059.FALSE
chr315114306TC0.00036RBSN-TRUEAluYSINE,Alu
chr131192650TG0.00727MATN1,MATN1-AS1+,-FALSE
chr156961756AG0.00265PLPP3-FALSE
chr1206566948GA0.00228SRGAP2+FALSE
chr136068369TC5.31121E-05PSMB2-TRUEAluScSINE,Alu
chr9140286415TC0.00254EXD3-FALSEAluSgSINE,Alu
chr119565338CT0.00631LOC101927895,EMC1+,-FALSE
chr1923542193TC0.00099ZNF91-TRUEAluYSINE,Alu
chr1109535128GA0.00063WDR47-FALSE
chr178142911TC0.00925ZZZ3-TRUEAluSxSINE,Alu
chr128835847AG0.00042SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr155207983TA0.00018MROH7-TTC4,TTC4+FALSE
chr2129024313AG0.00612HS6ST1-FALSE
chr111979814GA0.00041KIAA2013-FALSE
chr1230415244TC0.00360GALNT2+FALSE
chr140537941AC0.00627CAP1+FALSE(A)nSINE,Alu
chr12125511958AG0.00010THRIL-FALSEAluSx1SINE,Alu
chr3160213318TG0.00215KPNA4-FALSE
chr2201774185TC0.00921.FALSEAluSzSINE,Alu
chr5125961573AG0.00217PHAX+TRUEAluSz6SINE,Alu
chr1149783886CT0.00526HIST2H2BF-FALSE
chr5151041876GT5.29152E-05SPARC-FALSE
chr11622754AG0.00221CDK11B,SLC35E2B-FALSEMLT1F2SINE,Alu
chr131905887AC0.00221SERINC2+FALSE
chr129446554CA0.00682EPB41,TMEM200B+,-FALSE
chr127182750GC0.00141.FALSE
chr3101399939GT1.18387E-05RPL24-FALSE
chr154692674AG0.00864SSBP3-FALSE
chr1118068558GA0.00876.FALSE
chr110518756TC0.00937.FALSEAluSx1SINE,Alu
chr119665557AC0.00365CAPZB-FALSE
chr1918477761AG0.00461PGPEP1+TRUEAluJbSINE,Alu
chr4113197769TC0.00101TIFA-FALSE
chr1109465168TA0.00246GPSM2+FALSE
chr110519932TC5.00916E-05.FALSEAluJrSINE,Alu
chr1490865627TC0.00162CALM1+FALSE

Differential Expression Gene Analysis