Dataset Overview
RBPIGF2BP3
Knock-MethodshRNA
RBP FamilyKH_1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR710NWE
PlatformHiSeq
Pubmed ID32252787

IGF2BP3 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of IGF2BP3
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of IGF2BP3


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr110520487TC0.00710.FALSEAluSx1SINE,Alu
chr1145512014AG0.00023NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr7143003524GT3.66232E-05CASP2+FALSEAluYSINE,Alu
chr339138082CT8.26379E-05WDR48+FALSE
chrX77084001TC1.05736E-07MAGT1-TRUEAluSzSINE,Alu
chr116929148GA0.00037NBPF1-FALSELTR16B2SINE,Alu
chr136789546AG0.00562EVA1B-FALSEMIRbSINE,Alu
chr197116159GT0.00368INSR-FALSE
chr1942375584AG0.00021.FALSEAluSxSINE,Alu
chr128826150AG0.00052PHACTR4+TRUEAluJbSINE,Alu
chr5205565GA0.00593CCDC127-FALSE
chr3183533964TC2.38465E-05MAP6D1-FALSE
chr1160231910AT0.00051DCAF8-FALSE
chr1247319704TA0.00053ZNF124-FALSE
chr417804785TC0.00083DCAF16-TRUEAluSxSINE,Alu
chr699848757CT0.00951PNISR-FALSE(TCTTTT)nSINE,Alu
chr1110913120CT0.00627SLC16A4-FALSE
chr126608008TA0.00496SH3BGRL3+FALSE
chr3107526033TA0.00056BBX+FALSE
chr16282295TC0.00060ICMT-TRUEAluSzSINE,Alu
chr116918734GC0.00600NBPF1-FALSE
chr717384437AG0.00192AHR+TRUEAluSxSINE,Alu
chr1298943192AG0.00011TMPO+FALSEAluSzSINE,Alu
chr111084103TA0.00146TARDBP+FALSE
chr192946618AG0.00062GFI1-FALSE
chr128825337AG0.00313PHACTR4+TRUEAluSgSINE,Alu
chr1120839683GA0.00875FAM72B+FALSE
chr3183900729TC0.00074AP2M1+FALSEMIR3SINE,Alu
chr6151678865TG0.00016AKAP12+FALSE(T)nSINE,Alu
chr116893691CA0.00764NBPF1-FALSE
chr317201882CT0.00282TBC1D5-FALSE
chr110518797TC0.00148.FALSEAluSx1SINE,Alu
chr349131374GC0.00905QRICH1-FALSE(CCG)nSINE,Alu
chr369151152CA0.00750ARL6IP5+FALSE
chr1169468187GT0.00827CCND1+FALSE(T)nSINE,Alu
chr112401868AC0.00526VPS13D+FALSE
chr145187511TC7.71832E-06C1orf228+FALSEU5SINE,Alu
chr1145512944AG0.00110NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1179042701AG0.00132FAM20B+TRUEAluSx1SINE,Alu
chr140539210CA0.00185PPT1-FALSE
chr1932005AG0.00110.FALSE
chr10121437034GC0.00120BAG3+FALSE
chr124862643TG0.00933RCAN3+FALSE
chr128825805GA0.00115PHACTR4+FALSEAluSpSINE,Alu
chr146076543AG0.00989NASP+TRUEAluSxSINE,Alu
chr11344749AG0.00307.FALSEAluSx1SINE,Alu
chr1949472GA2.93477E-10ISG15+FALSE
chr1101443431CT0.00013SLC30A7+FALSEAluSq2SINE,Alu
chr162627128AG0.00087PATJ+TRUEAluSxSINE,Alu
chr128835847AG0.00042SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr1326539AG0.00719.FALSE
chr272403405AC0.00227EXOC6B-FALSEGA-richSINE,Alu
chr413604182TC1.45661E-06BOD1L1-FALSE
chr174672474GA0.00441FPGT-TNNI3K,FPGT+FALSEX12_DNASINE,Alu
chr153684924AG0.00347C1orf123-FALSEL1MA5ASINE,Alu
chr1117617705AG0.00031TTF2+FALSE
chr1648387296AG0.00058LONP2,MIR5095+TRUEAluJbSINE,Alu
chr1220231982TC0.00328RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr1911256697TC0.00039SPC24-TRUEAluJr4SINE,Alu
chrM8859GA0.00929.FALSE
chr1114519351TG0.00773HIPK1+FALSE
chr652860743TG1.01575E-05.FALSE7SKSINE,Alu
chr613789450TC0.00235MCUR1-TRUEAluSgSINE,Alu
chr4154257511CA0.00093TRIM2+FALSE(A)nSINE,Alu
chr186119441GA0.00905ZNHIT6-FALSE
chr111083183GT0.00342TARDBP+FALSE
chr194423352GA0.00087CHAF1A+FALSEGA-richSINE,Alu
chr255516090CT0.00643CCDC88A-FALSE
chr116200163AG1.36684E-05SPEN+FALSE
chr123636277AT0.00188HNRNPR-FALSE
chr16282224TC0.00062ICMT-TRUEAluSzSINE,Alu
chr579279309TG0.00167MTX3-FALSE
chr9136897584CA0.00060BRD3-FALSEA-richSINE,Alu
chr133148696AG0.00363SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr3124948047CG0.00670ZNF148-FALSE
chr163924020CT0.00945ITGB3BP-FALSE
chr3170113815GT0.00586SKIL+FALSE
chr1144909956GA0.00310NBPF20,PDE4DIP+,-FALSE
chr2238678004AG0.00631LRRFIP1+FALSE
chr743665371AT0.00430STK17A,COA1+,-FALSE(AG)nSINE,Alu
chr19161231TC0.00481.FALSEAluSxSINE,Alu
chr5157185319AG0.00100LSM11+TRUEAluSqSINE,Alu
chr122852880GC0.00247ZBTB40+FALSE
chr830535953TC7.17768E-07GSR-TRUEAluJrSINE,Alu
chr261276758AG0.00924PEX13+TRUEAluSpSINE,Alu
chr1226333558AC0.00052ACBD3-FALSE(CAAAA)nSINE,Alu
chr348787042TC1.97898E-05PRKAR2A-TRUEAluSx3SINE,Alu
chr237328097TC0.00301.FALSE
chr122352040GT0.00255LOC101928043,LINC00339+,-FALSE
chr131345785TA0.00962SDC3-FALSE
chr1114449662TC0.00223DCLRE1B+FALSE
chr128825337AG0.00191PHACTR4+TRUEAluSgSINE,Alu
chr142881767GC0.00437RIMKLA+FALSE
chr1810691357GA0.00082PIEZO2-FALSE
chr285776508AT0.00747GGCX-FALSEAluSz6SINE,Alu
chr1022825288GA0.00051PIP4K2A-FALSE
chr133148706AG0.00087SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr12303108TC5.78895E-05MORN1-FALSEAluSpSINE,Alu
chr1958356524AG0.00026ZNF587B+TRUEAluSxSINE,Alu
chr4141600320AG0.00179TBC1D9-FALSE
chr1204520000AG0.00032MDM4+TRUECharlie2aSINE,Alu
chr116842064AC0.00081.FALSEMER41ESINE,Alu
chr11419775AG0.00090ATAD3B+TRUEAluYk2SINE,Alu
chr1204525713AG0.00501MDM4+TRUEAluSzSINE,Alu
chr442089177GA0.00447SLC30A9+FALSE
chr1145513098AG0.00067NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr3178954055TC0.00308PIK3CA+FALSE
chr1100440553AG0.00553SLC35A3+TRUEAluJbSINE,Alu
chr147717189AG0.00384STIL-FALSE
chr237331065TC0.00527.FALSEAluSx1SINE,Alu
chr1749042381TC0.00931SPAG9-TRUEAluJbSINE,Alu
chr110520331CT0.00065.FALSEAluSx1SINE,Alu
chr5176863519GC0.00567GRK6+FALSE
chr12133298349AG2.42844E-07PGAM5+TRUEAluSpSINE,Alu
chr1214525603AG0.00047PTPN14-FALSE
chr11118661811TG0.00582DDX6-FALSE
chr116933637AG0.00062NBPF1-FALSEGA-richSINE,Alu
chr1161930908GA0.00083ATF6+FALSE
chr1169824104GA0.00744SCYL3-FALSE
chr1217804325GA0.00229GPATCH2-FALSE
chr1179042687AG0.00163FAM20B+TRUEAluSx1SINE,Alu
chr5139931631GC0.00138SRA1-FALSE
chr324019977AC0.00281NR1D2+FALSE
chr194351065AT0.00142GCLM-FALSE
chr1741144250GT0.00025RUNDC1+FALSE
chr5177576458AT0.00427.FALSE
chr1150281011AG0.00016MRPS21+TRUEAluSzSINE,Alu
chr1015119789TC0.00366ACBD7-TRUEAluSx1SINE,Alu
chr313670776TC0.00336FBLN2+FALSE
chr1921474901TC1.34658E-06ZNF708-TRUEAluScSINE,Alu
chr5125961623AG4.58304E-06PHAX+TRUEAluSz6SINE,Alu
chr1949468569GT0.00266FTL+FALSE
chr110421878AG7.26627E-05KIF1B+FALSE
chr353265957TC0.00493TKT-FALSE
chr133148367CG0.00020SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1201975173GT0.00356RNPEP+FALSE
chr133765752GA0.00963ZNF362+FALSE
chr12120898998AG0.00081GATC+TRUEAluJrSINE,Alu
chr140537924GA0.00404CAP1+FALSE(A)nSINE,Alu
chr132953296AG5.26589E-05ZBTB8B+TRUEAluSzSINE,Alu
chr139794147AC9.03176E-05MACF1+FALSE
chr1167511256TC0.00838CREG1-FALSE
chr153289688AG0.00069ZYG11B+TRUEAluSzSINE,Alu
chr144072018CT0.00783PTPRF+FALSE
chr3101405564GA0.00354.FALSE
chr933039686GA0.00542DNAJA1+FALSE
chr2206987205TC0.00039.FALSEAluSxSINE,Alu
chr633281842GT0.00514.FALSE
chr1194801632CA0.00194SRSF8+FALSE
chr1453243545TC3.01634E-08GNPNAT1-TRUEAluSx3SINE,Alu
chr9111781015AC0.00853TMEM245-FALSE
chr1738438362GA0.00016WIPF2+FALSEA-richSINE,Alu
chr177257878AG0.00027KCTD11+FALSE
chr132953214AG0.00837ZBTB8B+TRUEAluSzSINE,Alu
chr1431916944TC1.05468E-06LOC101927124,DTD2+,-FALSEAluSc8SINE,Alu
chr111084103TA0.00118TARDBP+FALSE
chr232535865AG0.00684.FALSEAluJbSINE,Alu
chr2203744240TC0.00595.FALSEAluSxSINE,Alu
chr1148241604GT0.00756NBPF8-FALSEU1SINE,Alu
chr2146353985AG0.00985LINC01547-FALSEMER5ASINE,Alu
chr7102016321CT0.00201LOC100289561,LOC100630923+FALSE
chr720177525TC0.00052MACC1,LOC101927668-TRUEAluSxSINE,Alu
chr254120820GA0.00262PSME4-FALSE
chr19732611TC0.00321PIK3CD,PIK3CD-AS2+,-FALSEAluJoSINE,Alu
chr1145689568AG8.25649E-05NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr1153617973AG4.00129E-07CHTOP+FALSE
chr237327685TC0.00057.FALSE
chr1197125427TC0.00331ZBTB41-FALSE
chr1741144251TG0.00014RUNDC1+FALSE
chr3156258319TC0.00237SSR3-TRUEAluYk3SINE,Alu
chr363987389TC0.00662ATXN7+FALSE
chr126188238GA0.00148PAQR7-FALSEAluSpSINE,Alu
chr110521200TC0.00013DFFA-TRUEAluYSINE,Alu
chr155316322AG0.00929DHCR24-FALSE
chr154691465CT0.00064SSBP3-FALSE
chr13806074GA0.00354C1orf174-FALSEAluSpSINE,Alu
chr126755643AG0.00428LIN28A+FALSEAluScSINE,Alu
chr185785549TC0.00320DDAH1-FALSE
chr3113604709TC0.00012GRAMD1C+FALSE
chr2132481470CT0.00594C2orf27A+FALSE
chr237327666TC0.00231.FALSE
chr133149399AG0.00148SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr237479862CT0.00603PRKD3-FALSE
chr136067784TC2.18848E-07PSMB2-TRUEAluSzSINE,Alu
chr5115166486TC0.00122ATG12-TRUEAluJrSINE,Alu
chr11345006AG0.00123.FALSEAluSgSINE,Alu
chr133148621AG0.00754SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr1145688944AG0.00359NBPF20,NBPF10,RNF115+TRUEAluSc8SINE,Alu
chr167874540TC0.00555SERBP1-FALSE
chr5118173627TC0.00075DTWD2-TRUE
chr1150621090GA0.00212GOLPH3L-FALSE
chr375474643TC0.00850FAM86DP-TRUEAluJoSINE,Alu
chr2133974094CT0.00880C21orf59-FALSE
chr1450053316TC0.00115.FALSE7SLRNASINE,Alu
chr330733403AT0.00840TGFBR2+FALSE(TA)nSINE,Alu
chr154691922TA0.00067SSBP3-FALSE
chr103208557AG0.00128PITRM1-FALSE
chr136067821TC8.78017E-05PSMB2-TRUEAluSzSINE,Alu
chr5145838680AG0.00395TCERG1+FALSE(GCCCAG)nSINE,Alu
chr833356827TA0.00122MAK16,TTI2+,-FALSE
chr19331227AG0.00181H6PD+TRUEAluSxSINE,Alu
chr127204516TC0.00028.FALSEAluSg7SINE,Alu
chr2201842323TC0.00591FAM126B-TRUEAluJbSINE,Alu
chr1144931727GA0.00521NBPF20,PDE4DIP+,-FALSE
chr115993013GA1.16652E-10.FALSE
chr2176792535TG0.00211LNPK-FALSE
chr1918477761AG0.00461PGPEP1+TRUEAluJbSINE,Alu
chr122854702CT5.42952E-11ZBTB40+FALSE
chr276672504AG0.00010.FALSE7SKSINE,Alu
chr116973198GA0.00514MST1P2+FALSE
chr1450361170CT0.00096ARF6+FALSE(T)nSINE,Alu
chr1145512059AG0.00053NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1590819423AG3.09408E-05.FALSEAluSxSINE,Alu
chr12123346999TA0.00838HIP1R+FALSE
chr1182543666TG0.00124RNASEL-FALSE
chr1148932848AG0.00715LOC645166+FALSE
chr2103333653TC0.00426MFSD9-FALSEAluYm1SINE,Alu
chr247604176CT0.00328EPCAM+FALSE
chr136067925TC4.53272E-07PSMB2-TRUEAluSzSINE,Alu
chr2178406765TA0.00325AGPS+FALSE
chr4159176109CA0.00042TMEM144+FALSEMIRSINE,Alu
chr1205320515AG0.00022KLHDC8A-FALSE
chr10114209912AG0.00060VTI1A+TRUEAluSx3SINE,Alu
chr8143744556TC0.00586JRK-TRUEAluJrSINE,Alu
chr439460539GA0.00323RPL9-FALSE
chr5125961623AG6.78430E-09PHAX+TRUEAluSz6SINE,Alu
chr342591446AG0.00012SEC22C-FALSE
chr352448770AG0.00498PHF7+TRUEAluJbSINE,Alu
chr116890286CT3.65680E-06NBPF1-FALSE
chr1146649940CT1.24118E-05PDIA3P1+FALSE
chr4156273768TC0.00058MAP9-FALSE
chr5118174668TC1.32199E-05DTWD2-TRUEAluYSINE,Alu
chr2242384368GA0.00031FARP2+FALSEAluJrSINE,Alu
chr1108742123CG1.29742E-06SLC25A24-FALSE
chr9132266648AG0.00230LINC00963+TRUEAluSxSINE,Alu
chr116933135GT0.00363NBPF1-FALSEL1MC2SINE,Alu
chr1245017464TA0.00624HNRNPU,SNORA100-FALSE
chr125570549CA0.00387RSRP1-FALSE
chr127205044TC0.00312.FALSEAluSxSINE,Alu
chr1156564754AG0.00562GPATCH4-FALSE
chr1145209366AG0.00499NBPF20,NOTCH2NL+FALSE
chr19815354TG0.00212CLSTN1-FALSE
chr574072648TA0.00036NSA2+FALSE
chr626095642AG0.00332.FALSEAluYSINE,Alu
chr3195460892AG0.00057.FALSEAluSgSINE,Alu
chr366024384GC0.00096MAGI1-FALSE
chr1214527252GA0.00830PTPN14-FALSEMADE2SINE,Alu
chr339137794TC0.00240WDR48+FALSE
chr1148251875TC0.00436NBPF8,NBPF14,NBPF9-FALSE
chr110517653TC0.00475.FALSEAluSx1SINE,Alu
chr116939857CT0.00542NBPF1-FALSE
chr116912029CG0.00831NBPF1-FALSE
chr127108139AT0.00683ARID1A+FALSE
chr811701490TC2.07071E-11CTSB-TRUEAluSx1SINE,Alu
chr110520174TC0.00163.FALSEAluSxSINE,Alu
chr136068275TC0.00625PSMB2-TRUEAluScSINE,Alu
chr1765334726TC7.47982E-07PSMD12-TRUEAluSqSINE,Alu
chr133148367CG0.00439SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1959095456AG0.00125CENPBD1P1+TRUEAluJbSINE,Alu
chr1946289409CT6.23760E-05DMWD-FALSE
chr2217366896AG0.00457.FALSEAluSz6SINE,Alu
chr1156567496CT0.00012GPATCH4-FALSEMIR3SINE,Alu
chr989626839TG0.00016LOC440173-FALSE
chr358306797AG8.72021E-05.FALSEAluSzSINE,Alu
chr1206579936AG0.00974SRGAP2+FALSE
chr3172115589GT0.00435FNDC3B+FALSE
chr2239259540GA0.00493CBX6-FALSE
chr344790781TC0.00887KIAA1143-TRUEAluYSINE,Alu
chr1145354360AC0.00761NBPF20,NBPF10+FALSE
chr1120163518CT0.00646ZNF697-FALSE
chr1229439639TA0.00276RAB4A+FALSE
chr5112350098CT7.36383E-05DCP2+FALSE
chr2062598815CT0.00711ZNF512B-FALSE
chr633385535AG0.00671.FALSE
chr119543356TC0.00256LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr119543247TC4.83051E-05LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr13416449CA0.00748MEGF6-FALSE
chr8144681777GT0.00383TIGD5+FALSE
chr439551166TC0.00309UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr187811105GA0.00025LMO4+FALSE
chr5118174735TC0.00046DTWD2-TRUEAluYSINE,Alu
chr189570148AG0.00084.FALSE
chr132661578CT0.00694TXLNA+FALSE(T)nSINE,Alu
chr1269237042AG0.00413MDM2+TRUE
chr2201774341TC0.00010.FALSEAluSzSINE,Alu
chr136067760TC1.59237E-06PSMB2-TRUEAluSzSINE,Alu
chr5148873854AG0.00453.FALSE
chr342610374AG0.00594SEC22C-FALSE
chr110517527TC0.00304.FALSEAluSx1SINE,Alu
chr5130537761AG0.00947LYRM7+FALSEAluJbSINE,Alu
chr133149443AG6.55200E-05SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1958420152CA0.00322ZNF417-FALSE
chr1352602919AC0.00117ALG11,UTP14C+FALSE
chr4119551832GA0.00522LOC729218+FALSE

Differential Expression Gene Analysis