Dataset Overview
RBP
IGF2BP3
Knock-Method
shRNA
RBP Family
KH_1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR710NWE
Platform
HiSeq
Pubmed ID
32252787
IGF2BP3 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of IGF2BP3
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
40.38
13.41
-1.89573
2.64479E-21
1.26883E-19
A2M
2827.98
2026.84
-0.74377
2.77391E-05
0.00015
AADAC
0.87
0.37
-1.50736
0.00039
0.00160
AADAT
2.45
8.45
1.21721
1.57882E-06
1.14447E-05
AAGAB
4.83
16.2
1.52565
6.60842E-14
1.47521E-12
AAK1
1.2
4.04
1.91825
9.73066E-16
2.65241E-14
AAMP
124.44
99.42
-0.68812
0.00054
0.00215
ABAT
17.85
29.69
0.39369
0.03215
0.07021
ABCA1
21.72
17.41
-0.61883
0.00098
0.00365
ABCA11P
2.08
5.47
1.08443
2.52639E-05
0.00014
Showing 1 to 10 of 6,547 entries
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Function Analysis of Target Genes of IGF2BP3
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABI2
204240779_204240855_204231599_204231767_204244930_204245000
0.00985
0.058
DataSet_01_111
View details
AFMID
76201520_76201599_76198783_76198832_76202026_76202131
0.00602
0.038
DataSet_01_111
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AHSG
186337645_186337729_186336300_186336426_186338374_186338579
0.00045
0.007
DataSet_01_111
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AHSG
186337645_186337863_186336324_186336426_186338374_186339107
0.00474
0.012
DataSet_01_111
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AHSG
186336079_186336177_186334975_186335139_186336324_186336426
0.00563
-0.007
DataSet_01_111
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AKAP8L
15509440_15509577_15508524_15508666_15510112_15510221
0.00011
0.12
DataSet_01_111
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AKAP8L
15509440_15509514_15508524_15508666_15510112_15510221
0.00012
0.117
DataSet_01_111
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AKR1A1
46034156_46034356_46033818_46033849_46034598_46034678
0.00000
-0.16
DataSet_01_111
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AMBP
116823204_116823403_116822406_116822550_116823703_116823871
0.00015
-0.066
DataSet_01_111
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ANKRD10
111552876_111553041_111545543_111545610_111558379_111558471
0.00048
0.27
DataSet_01_111
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52623792_52623840_52642377_52642465_52622648_52622741
0.00226
-0.549
DataSet_01_111
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ACP1
272036_272150_272191_272305_271865_271939
0.00778
0.058
DataSet_01_111
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ACP1
272036_272150_272191_272305_271865_271939
0.00901
0.066
DataSet_01_111
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ACSS3
81532909_81533044_81536885_81537026_81528594_81528783
0.00002
-0.198
DataSet_01_111
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AHSG
186337645_186337729_186338374_186338579_186336300_186336426
0.00000
0.018
DataSet_01_111
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AHSG
186336079_186336280_186336324_186336426_186334975_186335139
0.00000
-0.013
DataSet_01_111
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AHSG
186336079_186336280_186337645_186337863_186334975_186335139
0.00003
-0.392
DataSet_01_111
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AHSG
186336300_186336426_186337645_186337729_186334975_186335139
0.00034
-0.006
DataSet_01_111
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AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00056
-0.007
DataSet_01_111
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APEH
49711921_49712054_49712615_49712742_49711799_49711846
0.00612
-0.123
DataSet_01_111
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AKAP8L
15509440_15510221_15510112_15510221_15508524_15508666
0.00010
0.112
DataSet_01_111
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ANKZF1
220100182_220100343_220100182_220100307_220100429_220100597
0.00021
0.16
DataSet_01_111
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CFB
31914262_31914443_31914262_31914383_31914783_31914969
0.00000
0.095
DataSet_01_111
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GMPR2
24702158_24702266_24702158_24702183_24702424_24702546
0.00323
-0.093
DataSet_01_111
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LARP1
154173359_154173560_154173359_154173461_154173659_154173822
0.00495
-0.139
DataSet_01_111
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NOP56
2636579_2636860_2636579_2636680_2637046_2637195
0.00000
-0.206
DataSet_01_111
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PARP3
51979868_51980078_51979868_51979955_51980181_51980359
0.00556
-0.096
DataSet_01_111
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PHPT1
139744464_139745012_139744464_139744589_139745206_139745474
0.00154
-0.049
DataSet_01_111
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PSMB5
23496934_23497038_23496953_23497038_23495398_23495584
0.00756
0.229
DataSet_01_111
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RPL41
56510558_56510714_56510558_56510583_56510972_56510995
0.00888
-0.009
DataSet_01_111
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Showing 1 to 10 of 17 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCG5
44055121_44055607_44055121_44055254_44058907_44059006
0.00811
-0.089
DataSet_01_111
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ABLIM1
116207638_116207819_116207638_116207779_116211382_116211430
0.00137
-0.215
DataSet_01_111
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C17orf76-AS1
16342841_16343017_16342973_16343017_16342640_16342728
0.00989
-0.076
DataSet_01_111
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C1orf63
25570040_25570715_25570040_25570124_25571640_25571792
0.00037
0.411
DataSet_01_111
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C3
6712518_6712613_6712518_6712575_6713199_6713326
0.00002
-0.159
DataSet_01_111
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COL27A1
117051451_117051575_117051521_117051575_117051193_117051247
0.00966
0.034
DataSet_01_111
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DDX41
176942186_176942340_176942186_176942259_176942685_176942822
0.00804
0.066
DataSet_01_111
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GABPB1
50581679_50581865_50581679_50581862_50592985_50593099
0.00998
0.083
DataSet_01_111
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METTL17
21460250_21460364_21460282_21460364_21458622_21458757
0.00537
0.104
DataSet_01_111
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MORF4L2
102933426_102933579_102933426_102933548_102940098_102940155
0.00193
-0.101
DataSet_01_111
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AAMP
219130301_219130669_219130301_219130405_219130553_219130669
0.00810
0.064
DataSet_01_111
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ACTB
5567911_5569031_5567911_5568350_5568791_5569031
0.00214
0.015
DataSet_01_111
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AHCY
32878137_32878444_32878137_32878255_32878356_32878444
0.00492
0.012
DataSet_01_111
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ARSA
51065983_51066598_51065983_51066220_51066373_51066598
0.00393
0.265
DataSet_01_111
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C17orf76-AS1
16342640_16343017_16342640_16342728_16342841_16343017
0.00000
0.043
DataSet_01_111
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C17orf76-AS1
16342350_16342728_16342350_16342374_16342640_16342728
0.00200
0.024
DataSet_01_111
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C17orf76-AS1
16342640_16343567_16342640_16342728_16343498_16343567
0.00325
0.017
DataSet_01_111
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C17orf76-AS1
16342894_16343567_16342894_16343017_16343498_16343567
0.00406
0.038
DataSet_01_111
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C1orf63
25570040_25571792_25570040_25570124_25571640_25571792
0.00107
0.258
DataSet_01_111
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CALCOCO1
54107484_54108025_54107484_54107684_54107916_54108025
0.00877
-0.202
DataSet_01_111
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
10520487
T
C
0.00710
.
FALSE
AluSx1
SINE,Alu
chr1
145512014
A
G
0.00023
NBPF20,NBPF10,RBM8A,GNRHR2
+,-
FALSE
AluY
SINE,Alu
chr1
16929148
G
A
0.00037
NBPF1
-
FALSE
LTR16B2
SINE,Alu
chr1
36789546
A
G
0.00562
EVA1B
-
FALSE
MIRb
SINE,Alu
chr1
28826150
A
G
0.00052
PHACTR4
+
TRUE
AluJb
SINE,Alu
chr1
160231910
A
T
0.00051
DCAF8
-
FALSE
chr1
247319704
T
A
0.00053
ZNF124
-
FALSE
chr1
110913120
C
T
0.00627
SLC16A4
-
FALSE
chr1
26608008
T
A
0.00496
SH3BGRL3
+
FALSE
chr1
6282295
T
C
0.00060
ICMT
-
TRUE
AluSz
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression