Dataset Overview
RBP
XRCC6
Knock-Method
shRNA
RBP Family
SAP
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR500WHE
Platform
HiSeq
Pubmed ID
32252787
XRCC6 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of XRCC6
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
9.32
4.2
-1.24725
7.01943E-22
1.12946E-20
A1CF
29.34
33.4
0.16935
0.00620
0.01287
A2M
2342.22
1311.36
-1.01273
1.59823E-75
1.83782E-73
A2M-AS1
0.34
0.68
0.73813
0.03922
0.06671
AACS
15.41
12.19
-0.51839
2.57171E-12
2.02145E-11
AADAT
6.38
10.64
0.61462
3.68860E-09
2.08750E-08
AAED1
6.05
4.92
-0.52705
3.67660E-06
1.38303E-05
AAGAB
9.04
16.67
0.83674
9.34605E-24
1.72908E-22
AAK1
2.94
6.18
0.97277
2.39788E-18
3.06666E-17
AAMDC
19.44
11.8
-0.83767
4.49981E-07
1.93249E-06
Showing 1 to 10 of 8,088 entries
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Function Analysis of Target Genes of XRCC6
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52610424_52610567_52603747_52603882_52619601_52619745
0.00691
-0.081
DataSet_01_114
View details
ABI1
27044583_27044670_27040526_27040712_27047990_27048167
0.00076
-0.151
DataSet_01_114
View details
AC005154.6
30591715_30591795_30589936_30590397_30601081_30601744
0.00525
-0.244
DataSet_01_114
View details
ACAA1
38167652_38167822_38167316_38167372_38168000_38168115
0.00008
-0.623
DataSet_01_114
View details
ACAA1
38167652_38167832_38167316_38167372_38168000_38168191
0.00016
-0.087
DataSet_01_114
View details
ACAA1
38167652_38167843_38167316_38167372_38168000_38168191
0.00040
-0.11
DataSet_01_114
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ACSL3
223765391_223765498_223725651_223725976_223773450_223773754
0.00019
0.036
DataSet_01_114
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ACSL3
223752547_223752606_223725651_223725976_223773450_223773868
0.00617
0.019
DataSet_01_114
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ACSM2B
20586743_20586871_20575990_20576175_20587528_20587599
0.00763
0.082
DataSet_01_114
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ACTR10
58686411_58686447_58681922_58682002_58690339_58690419
0.00677
-0.081
DataSet_01_114
View details
Showing 1 to 10 of 374 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52603747_52603882_52619601_52619745_52601621_52601752
0.00108
-0.155
DataSet_01_114
View details
AFMID
76200908_76200981_76201520_76201599_76198783_76198832
0.00067
-0.178
DataSet_01_114
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AFP
74310709_74310839_74313330_74313393_74309063_74309161
0.00000
-0.293
DataSet_01_114
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AFP
74306318_74306530_74309067_74309161_74303890_74304023
0.00001
-0.012
DataSet_01_114
View details
AHSG
186336285_186336426_186337645_186337729_186334975_186335139
0.00062
0.016
DataSet_01_114
View details
ALB
74272345_74272478_74275071_74275140_74270832_74270890
0.00000
-1.0
DataSet_01_114
View details
ALB
74272345_74272478_74275071_74275204_74270017_74270123
0.00000
0.797
DataSet_01_114
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ALB
74272345_74272478_74275071_74275140_74270017_74270123
0.00000
-0.416
DataSet_01_114
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ANKRD54
38228964_38229116_38229165_38229213_38228643_38228751
0.00160
0.256
DataSet_01_114
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AP3S1
115202366_115202458_115205713_115205825_115177177_115177803
0.00009
-0.247
DataSet_01_114
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Showing 1 to 10 of 115 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAA1
38167652_38168191_38168000_38168191_38167316_38167372
0.00037
-0.111
DataSet_01_114
View details
AL163636.6
21152745_21152917_21152745_21152855_21167513_21168735
0.00690
0.013
DataSet_01_114
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APEX1
20923736_20923932_20923736_20923862_20924072_20924260
0.00350
-0.018
DataSet_01_114
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APOH
64224133_64224278_64224137_64224278_64219815_64219892
0.00389
0.129
DataSet_01_114
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ARMC10
102724128_102724509_102724128_102724277_102727076_102727211
0.00992
-0.09
DataSet_01_114
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ATG4B
242590424_242590750_242590424_242590526_242592926_242593025
0.00014
-0.105
DataSet_01_114
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BRD2
32945941_32946165_32945941_32946091_32947604_32947909
0.00720
0.03
DataSet_01_114
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CTNND1
57529268_57529540_57529268_57529518_57563048_57563213
0.00867
-0.163
DataSet_01_114
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EXOC3L4
103574732_103574974_103574732_103574854_103576367_103576521
0.00358
-0.209
DataSet_01_114
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FST
52780045_52780162_52780045_52780123_52780829_52781057
0.00309
-0.172
DataSet_01_114
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Showing 1 to 10 of 39 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
APOA5
116662527_116662584_116662527_116662579_116663095_116663127
0.00521
-0.5
DataSet_01_114
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APOB
21265232_21265410_21265232_21265348_21266384_21266423
0.00060
-0.01
DataSet_01_114
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ASNS
97483891_97484066_97483891_97483992_97484664_97484771
0.00829
-0.042
DataSet_01_114
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BAP1
52436794_52436956_52436794_52436887_52437153_52437314
0.00058
0.071
DataSet_01_114
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BAX
49464739_49464970_49464788_49464970_49464066_49464171
0.00506
0.105
DataSet_01_114
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BCOR
39922860_39923205_39922860_39923103_39923588_39923852
0.00682
-0.171
DataSet_01_114
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C17orf76-AS1
16342894_16343017_16342973_16343017_16342640_16342728
0.00250
0.095
DataSet_01_114
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CIB1
90775450_90775679_90775450_90775559_90776900_90776935
0.00734
0.12
DataSet_01_114
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DCAF11
24586125_24586253_24586196_24586253_24584590_24584958
0.00472
-0.185
DataSet_01_114
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DDX41
176943288_176943517_176943288_176943448_176943725_176943836
0.00687
-0.063
DataSet_01_114
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9220307_9220820_9220307_9220435_9220778_9220820
0.00980
0.008
DataSet_01_114
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AACS
125609250_125609570_125609250_125609315_125609447_125609570
0.00569
0.186
DataSet_01_114
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AAMP
219130301_219130669_219130301_219130405_219130553_219130669
0.00351
0.117
DataSet_01_114
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ABCB6
220075102_220075545_220075102_220075197_220075432_220075545
0.00787
0.066
DataSet_01_114
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ACAA1
38167316_38168191_38167316_38167372_38167652_38168191
0.00282
0.039
DataSet_01_114
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ACTB
5567911_5569031_5567911_5568350_5568791_5569031
0.00232
-0.007
DataSet_01_114
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ADCY6
49167251_49167881_49167251_49167430_49167722_49167881
0.00303
-0.185
DataSet_01_114
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ANKZF1
220097800_220098155_220097800_220097913_220098007_220098155
0.00524
0.097
DataSet_01_114
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BAP1
52436794_52437314_52436794_52436887_52437153_52437314
0.00139
0.054
DataSet_01_114
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BAX
49464066_49465055_49464066_49464171_49464788_49465055
0.00234
0.189
DataSet_01_114
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
33148367
C
G
0.00020
SYNC,RBBP4
+,-
FALSE
AluSg
SINE,Alu
chr1
11119950
G
A
4.66412E-05
SRM
-
FALSE
chr1
9644558
A
G
0.00451
.
FALSE
AluSx
SINE,Alu
chr1
204526795
A
G
0.00199
MDM4
+
TRUE
AluSx
SINE,Alu
chr1
6614188
C
T
0.00906
NOL9
-
FALSE
chr1
36067677
T
C
5.01583E-07
PSMB2
-
TRUE
AluSz
SINE,Alu
chr1
173864944
G
T
2.40127E-05
.
FALSE
chr1
117648345
A
G
0.00739
.
FALSE
chr1
209605646
A
C
0.00478
MIR205HG
+
FALSE
(AGC)n
SINE,Alu
chr1
19543352
T
C
0.00715
LOC101927895,EMC1
+,-
FALSE
AluJb
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression