Dataset Overview
RBPDDX21
Knock-MethodshRNA
RBP FamilyDEAD
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR961WVL
PlatformHiSeq
Pubmed ID32252787

DDX21 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of DDX21
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of DDX21


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr830536544TC5.33169E-07GSR-TRUEAluSpSINE,Alu
chr138174665GA0.00339CDCA8+FALSE
chr1725640011AG0.00228WSB1+TRUEAluSxSINE,Alu
chr136535590AG0.00301.FALSEAluSx1SINE,Alu
chr1222907790CT0.00253BROX+FALSE
chr1753470462CT0.00230MMD-FALSE
chr2217366674AG0.00889.FALSEAluSzSINE,Alu
chr110519888TC0.00878.FALSEAluJrSINE,Alu
chr763808867CA0.00556ZNF736+FALSE
chr1150619971GA0.00126GOLPH3L-FALSEAluJoSINE,Alu
chr128218100TC0.00080RPA2-FALSE
chr572801321TA0.00212BTF3+FALSE
chr11594940TC0.00115CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr1244572645TG0.00218ADSS-FALSE
chr29629305AT0.00079ADAM17-FALSE
chr9132268442AG0.00642LINC00963+TRUEAluJbSINE,Alu
chr1203766875TC3.09664E-07ZC3H11A,ZBED6+FALSE
chr116953672CT0.00243CROCCP2-FALSE
chr369026314GA0.00881EOGT-FALSEAluSz6SINE,Alu
chr1205320515AG0.00022KLHDC8A-FALSE
chr1225974614AG0.00209SRP9+TRUEAluJrSINE,Alu
chr5178986978CG0.00341RUFY1+FALSE
chr19331255AG0.00992H6PD+TRUEAluSxSINE,Alu
chr7128294489GT0.00354LINC01000+FALSE
chr2101622888TA0.00210RPL31+FALSE
chr2206982296TC0.00720.FALSEAluSg7SINE,Alu
chr2218572728AG0.00050PEX26+TRUEAluYf1SINE,Alu
chr131342611AC0.00145SDC3-FALSE
chr129443675TC0.00190EPB41+FALSE
chr4123816376AT0.00445FGF2,NUDT6+,-FALSE
chr74802065CT0.00279FOXK1+FALSE
chr189447720GA0.00029KYAT3,RBMXL1-FALSE
chr717384334AG0.00013AHR+TRUEAluSxSINE,Alu
chr2220406239TG0.00035CHPF-FALSEMIRbSINE,Alu
chr76501828CA0.00114KDELR2-FALSE
chr110520378TC0.00895.FALSEAluSx1SINE,Alu
chr124296708AG0.00512.FALSE
chr2218571343AG0.00501PEX26+TRUEAluSzSINE,Alu
chr171532815GA0.00712ZRANB2-AS1,ZRANB2+,-FALSE
chr1120163247TC0.00365ZNF697-FALSE
chr1142660072TG0.00773.FALSE
chr454244053GC0.00726FIP1L1+FALSE(CGGAG)nSINE,Alu
chr3182632684GA0.00116ATP11B+FALSE
chr1220231263TC0.00300RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr132096265AG0.00208PEF1-FALSE
chr5179048449TG0.00394HNRNPH1-FALSE
chr146828700AG0.00273NSUN4+FALSE
chr643582895AG0.00983POLH+TRUEAluSx1SINE,Alu
chr35258236GC3.37681E-06EDEM1+FALSE
chr764435684TG0.00239ZNF117-FALSE
chr272403405AC0.00227EXOC6B-FALSEGA-richSINE,Alu
chr1346530764TG0.00385.FALSE
chr11469787CT0.00010ATAD3A+FALSE
chr119543459TC0.00395LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr121100862CA0.00012HP1BP3-FALSE(AC)nSINE,Alu
chr1419685015CG0.00069DUXAP10+FALSE
chr1145375858TC0.00069NBPF20,NBPF10+FALSE
chr19162223TC0.00778.FALSEAluSxSINE,Alu
chr145279903CT0.00052.FALSE(TCTT)nSINE,Alu
chr167874689TC0.00338SERBP1-TRUEAluSx3SINE,Alu
chr124086794GT0.00028TCEB3+FALSE(T)nSINE,Alu
chr11118888992CG0.00222RPS25-FALSE
chr613789467TC0.00019MCUR1-TRUEAluSgSINE,Alu
chr165693725CT0.00202AK4+FALSE
chr165900357GT0.00851LEPR,LEPROT+FALSE
chr110520487TC0.00559.FALSEAluSx1SINE,Alu
chr115909744CT0.00225AGMAT-FALSE
chr155316322AG0.00929DHCR24-FALSE
chr191863170GA0.00204KLF16-FALSE
chr189649522TC0.00358GBP4-TRUEAluJbSINE,Alu
chr1646614656TA0.00565SHCBP1-FALSE
chr8128752685GA0.00000MYC+FALSE
chr299812843AG0.00966MRPL30+TRUEAluJbSINE,Alu
chr190401562CA0.00057LRRC8D+FALSE
chr349762662GT6.99764E-06IP6K1-FALSE
chr7117832138GA0.00885LSM8+FALSE
chr117928TA0.00956WASH7P-FALSE
chr2132481508CG0.00093C2orf27A+FALSE
chr514397238TC0.00552TRIO+FALSE
chr145452227GC0.00084EIF2B3-FALSE
chr830536078TC5.73232E-10GSR-FALSEAluJrSINE,Alu
chr110517314TC0.00617.FALSEAluJrSINE,Alu
chr153289852AG0.00228ZYG11B+TRUEFRAMSINE,Alu
chr314986080TC4.44089E-16FGD5-AS1-TRUEFLAM_CSINE,Alu
chr1149913513TC0.00495OTUD7B-TRUEMER96BSINE,Alu
chr45743512TC0.00045EVC+FALSE
chr3191114266TC0.00258CCDC50+FALSE
chr1674655591TG0.00652RFWD3-FALSEAluSxSINE,Alu
chr2164466038CA0.00021FIGN-FALSE
chr116889044TA0.00256NBPF1-FALSE
chr1629454295TC0.00019SMG1P6,BOLA2-SMG1P6-TRUETigger4aSINE,Alu
chr3188602081AC7.06828E-05LPP+FALSEMIRcSINE,Alu
chr250148477CT0.00741NRXN1-FALSE
chr13730332TC9.76659E-06CEP104-TRUEAluSx3SINE,Alu
chr1113455427TA0.00814SLC16A1-FALSE
chr12335871GA0.00298RER1+FALSE
chr261277486AG0.00355PEX13+TRUEAluSxSINE,Alu
chr3176739159AC0.00304TBL1XR1-FALSE
chr4152025795TA0.00516RPS3A+FALSE
chr1100549600GT0.00181SASS6-FALSE
chr12125269489CT0.00817SCARB1-FALSE
chr1167795299GA0.00764ALDH3B1+FALSE
chr417802783TC6.83941E-07DCAF16-TRUEAluSzSINE,Alu
chr165897981GA0.00071LEPR,LEPROT+FALSE
chr147844500TG0.00169CMPK1+FALSE
chr136068276TC0.00225PSMB2-TRUEAluScSINE,Alu
chr344790781TC0.00289KIAA1143-TRUEAluYSINE,Alu
chr1117530213GT0.00256PTGFRN+FALSE
chr7105162638GC0.00155PUS7-FALSE
chr154412181TC0.00524LRRC42+FALSE
chr261277775AG0.00640PEX13+TRUEAluYSINE,Alu
chr1740466890GT0.00260STAT3-FALSEAluSc8SINE,Alu
chr1757279281AG0.00918PRR11+TRUEAluSq2SINE,Alu
chr1749042289GT0.00737SPAG9-FALSEAluJbSINE,Alu
chr269685864AC0.00610AAK1-FALSE(CA)nSINE,Alu
chr1145688664AT0.00081NBPF20,NBPF10,RNF115+FALSE
chr19740894CT0.00097PIK3CD,PIK3CD-AS2+,-FALSEMLT1F1SINE,Alu
chr1186281696TG0.00564PRG4,TPR+,-FALSE
chr136067749TC0.00735PSMB2-TRUEAluSzSINE,Alu
chr6150046734TC0.00248NUP43-FALSE
chr285132775CG7.25564E-06TMSB10+FALSE
chr2217366197TA0.00018.FALSE
chr3109049177AT0.00044DPPA4-FALSEAluSpSINE,Alu
chr4153898736AG0.00574FHDC1+FALSEAluJbSINE,Alu
chr1205687365CT0.00071NUCKS1-FALSE(T)nSINE,Alu
chr2224621887TC0.00373AP1S3-FALSEAluScSINE,Alu
chr1935741552CT0.00165LSR+FALSE
chr1145511929AG0.00028NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr2220370192CT0.00055GMPPA+FALSE
chr5175802154CT0.00883.FALSE(CATC)nSINE,Alu
chr116889985TC0.00583NBPF1-FALSE
chr123833608GA0.00890E2F2-FALSE
chr153366673AG0.00243ECHDC2-FALSEAluJbSINE,Alu
chr42940430TC2.47251E-05NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr274442548CT0.00035.FALSE
chr537291446TC6.87884E-05.FALSEAluSx3SINE,Alu
chr110521254TC0.00684DFFA-TRUEAluYSINE,Alu
chr110518821TC0.00913.FALSEAluSx1SINE,Alu
chr110521130TC0.00807DFFA-TRUEAluYSINE,Alu
chr2164466039AC0.00456FIGN-FALSE
chr19162362TC0.00526.FALSEAluSxSINE,Alu
chr357612271TC0.00831DENND6A,PDE12+,-FALSEAluSpSINE,Alu
chr110043504AG0.00213NMNAT1+FALSEAluSx3SINE,Alu
chr76501830GA0.00217KDELR2-FALSE
chr143629979GT0.00470EBNA1BP2-FALSE
chr1671681515AG0.00308PHLPP2-FALSE
chr12133298095AG0.00081PGAM5+TRUEAluJoSINE,Alu
chr167874859TC0.00071SERBP1-TRUEAluSxSINE,Alu
chr4177252327AG2.51883E-09SPCS3+TRUE
chr1184762627TC0.00416FAM129A-TRUEAluSzSINE,Alu
chr1146650363TA0.00982PDIA3P1+FALSE
chr272405098CA0.00646EXOC6B-FALSE
chr123409538GA0.00464KDM1A+FALSE
chr1154128838GT0.00062TPM3-FALSE
chr7158679732GA0.00456WDR60+FALSE
chr147905555AC0.00661FOXD2+FALSE
chr110517527TC8.32015E-05.FALSEAluSx1SINE,Alu
chr116893721AC0.00043NBPF1-FALSE
chr10117823566GT0.00433GFRA1-FALSE(ATC)nSINE,Alu
chr13730400TC6.07343E-08CEP104-TRUEAluSx3SINE,Alu
chr1919793795AG0.00030ZNF101+TRUEAluSc8SINE,Alu
chr128662105AG0.00846MED18+TRUEAluSq2SINE,Alu
chr1176733945AT0.00931ACER3+FALSEA-richSINE,Alu
chr14100762714TC0.00573SLC25A29-TRUEAluJoSINE,Alu
chr1610623705TC0.00011EMP2-TRUEAluSpSINE,Alu
chr6158517308AG0.00959SYNJ2+FALSE
chr6158613393AT0.00108GTF2H5+FALSE
chr1210761846AG0.00224MAGOHB-FALSE
chr1748155425GA0.00603ITGA3+FALSE
chr1011912065CG0.00191PROSER2-AS1,PROSER2+,-FALSE
chr4120979178TC0.00433.FALSEAluSg4SINE,Alu
chr136770065CT0.00131THRAP3+FALSE(T)nSINE,Alu
chr189447854GT0.00310KYAT3,RBMXL1-FALSE
chr139470977CA0.00347AKIRIN1+FALSEAluSx1SINE,Alu
chr237327670TC0.00021.FALSE
chr112401868AC0.00394VPS13D+FALSE
chr3141164940CA0.00194ZBTB38+FALSE
chr3124948047CG0.00670ZNF148-FALSE
chr1145512925AG0.00230NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr114143003AG0.00028PRDM2+FALSE
chr1921474901TC1.34658E-06ZNF708-TRUEAluScSINE,Alu
chr187328400CT0.00755SEP15-FALSE
chr2035467713GA0.00373SOGA1-FALSE
chr3196670090GA6.78352E-09NCBP2-AS2+FALSE
chr119244904GA0.00487IFFO2-FALSE
chr110520683TC0.00582DFFA-TRUEAluSc8SINE,Alu
chr1688789702GA0.00125PIEZO1-FALSE
chr128060574AG0.00206FAM76A+FALSE
chr1183112505TC0.00525LAMC1+FALSE
chr1160966376TC0.00996F11R-TRUEAluSgSINE,Alu
chr1109476363AG0.00172GPSM2,CLCC1+,-FALSE
chr119585554AG2.15626E-06MRTO4+TRUEAluSc8SINE,Alu
chr1773940918TC6.48265E-05ACOX1-TRUEAluSx1SINE,Alu
chr1450361171CT0.00017ARF6+FALSE(T)nSINE,Alu
chr2128620435CA0.00602AMMECR1L-FALSE
chr1165631670TG0.00197ALDH9A1-FALSE
chr2206980072GA1.35396E-05.FALSEMLT1A1SINE,Alu
chr314986110TC0.00051FGD5-AS1-TRUEFLAM_CSINE,Alu
chr1937073373TC0.00492ZNF529,ZNF529-AS1+,-FALSEAluYSINE,Alu
chr299812817AG0.00201MRPL30+TRUEAluJbSINE,Alu
chr1144873887CT0.00088NBPF20,PDE4DIP+,-FALSE
chr1220231347TC2.85871E-07RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr19161011TC7.97270E-05.FALSEAluJbSINE,Alu
chr3128215735GA0.00734GATA2-AS1+FALSE
chr125570561TA0.00425RSRP1-FALSEAluSINE,Alu
chr12303108TC5.78895E-05MORN1-FALSEAluSpSINE,Alu
chr1182569318GT0.00101RGS16-FALSE
chr19163110TC4.21626E-05.FALSEFRAMSINE,Alu
chr110520296TC0.00108.FALSEAluSxSINE,Alu
chr2178406765TA0.00325AGPS+FALSE
chr1542503334CT0.00448TMEM87A-FALSE(T)nSINE,Alu
chr1765334766TC4.45484E-05PSMD12-TRUEAluSqSINE,Alu
chr159142713TC0.00246MYSM1-FALSE
chr483812317CA0.00553SEC31A-FALSE
chr116909220TC0.00449NBPF1-FALSE
chr1472041443CT0.00842SIPA1L1+FALSE
chr1957816261AG0.00156.FALSEAluYSINE,Alu
chr2174090320TA0.00174ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr138174665GA0.00475CDCA8+FALSE
chr97798518GC0.00423TMEM261-FALSE
chr657034841GT0.00581ZNF451,LOC101927211+,-FALSE
chr1950412217CG0.00017IL4I1,NUP62-FALSE(GGT)nSINE,Alu
chr3122283293CG0.00071DTX3L,PARP9+,-FALSE
chr18412652AC0.00929RERE-FALSE
chr110520684TC0.00842DFFA-TRUEAluSc8SINE,Alu
chr1204521590AG1.33621E-05MDM4+TRUEAluSgSINE,Alu
chr348787715TC0.00863PRKAR2A-TRUEAluSpSINE,Alu
chr133149414AG5.81443E-05SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr122186113TG0.00083HSPG2-FALSE
chr167874689TC0.00112SERBP1-TRUEAluSx3SINE,Alu
chr417804879TC0.00863DCAF16-TRUEAluSxSINE,Alu
chr1463841402AC0.00692PPP2R5E-FALSE
chr1143398850GT0.00639.FALSE
chr110520692TC0.00973DFFA-TRUEAluSc8SINE,Alu
chr1205687354TC0.00012NUCKS1-FALSE(T)nSINE,Alu
chr4129924977CA0.00760SCLT1-FALSE
chr153716416GA0.00967LRP8-FALSE
chr127180861CT0.00721ZDHHC18+FALSE
chr1160231910AT0.00051DCAF8-FALSE
chr145976269CG0.00039MMACHC+FALSE
chr116893686GC0.00296NBPF1-FALSE
chr12133297961AG1.06136E-06PGAM5+TRUEAluJoSINE,Alu
chr348787684TC0.00494PRKAR2A-TRUEAluSpSINE,Alu
chr285773623TC0.00203GGCX-TRUEAluSx1SINE,Alu
chr146032974TC0.00196AKR1A1+FALSE
chrX102613351AG0.00969TCEAL9+FALSEL1ME4aSINE,Alu
chr237331019TC0.00597.FALSEAluSx1SINE,Alu
chr1236208773CT0.00722NID1-FALSE
chr1563363388GT0.00096TPM1+FALSE
chr116890484GC0.00704NBPF1-FALSE
chr1204521580AG0.00169MDM4+TRUEAluSgSINE,Alu
chr186986227GA3.73397E-05LAMA1-FALSE
chr1210025751GA4.42687E-05DIEXF+FALSETigger4aSINE,Alu
chr286249930TC0.00269LOC90784-TRUEAluJrSINE,Alu

Differential Expression Gene Analysis