Dataset Overview
RBPDDX21
Knock-MethodshRNA
RBP FamilyDEAD
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR485ZTC
PlatformHiSeq
Pubmed ID32252787

DDX21 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of DDX21
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of DDX21


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr286272758GA0.00023POLR1A-FALSE
chr457326313AG0.00132PAICS+TRUEAluJrSINE,Alu
chr1541593308AG0.00619.FALSEAluSz6SINE,Alu
chr3126755134CT0.00920PLXNA1+FALSE
chr1958356478AG0.00030ZNF587B+TRUEAluSxSINE,Alu
chr417803681TC3.85233E-06DCAF16-TRUEAluYSINE,Alu
chr167874689TC1.72813E-06SERBP1-TRUEAluSx3SINE,Alu
chr1684778690CT0.00799USP10+FALSE
chr8144940794GC0.00038EPPK1-FALSE
chr128662253AG0.00187MED18+TRUEAluSq2SINE,Alu
chr28823958GA0.00017ID2+FALSE
chr1179042544AG0.00722FAM20B+TRUEAluSx1SINE,Alu
chr1146629399GT0.00611PRKAB2-FALSE
chr18413839AG0.00776RERE-FALSE
chr153291434AG0.00545ZYG11B+TRUEAluJrSINE,Alu
chr1148932848AG0.00496LOC645166+FALSE
chr3124948047CG0.00285ZNF148-FALSE
chr1623478710CA0.00335GGA2-FALSE(AC)nSINE,Alu
chr133071096AG0.00692ZBTB8A+TRUEAluSx1SINE,Alu
chr19161090AG0.00068.FALSEAluJbSINE,Alu
chr210074384GA0.00765TAF1B+FALSE
chr1951305797TC0.00397C19orf48-TRUEAluSgSINE,Alu
chr314986104TC0.00992FGD5-AS1-TRUEFLAM_CSINE,Alu
chr9130268408TC6.51633E-05FAM129B-FALSE(CTCA)nSINE,Alu
chr1145512141AG0.00215NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr237331565TC0.00121.FALSEAluJbSINE,Alu
chr112071680AG0.00127MFN2+FALSE
chr12124146597AG0.00121GTF2H3+TRUEAluSq2SINE,Alu
chr738763068TC0.00361.FALSEAluSx3SINE,Alu
chr5125962086AG0.00231PHAX+TRUEAluSzSINE,Alu
chr128661653AG9.75782E-05MED18+TRUEAluSgSINE,Alu
chr2202030111AG0.00983CFLAR+TRUEAluSx1SINE,Alu
chr8145159718GC0.00409MAF1+FALSE
chr2229890660AG0.00596PID1-FALSE
chr1205737682AG0.00320RAB29-FALSEAluSq2SINE,Alu
chr116133912TC0.00126UQCRHL-TRUE
chr1145512074AG0.00084NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1151742798TC0.00626OAZ3+FALSE
chr2233257373GA0.00581SYN3,TIMP3+,-FALSE
chr16282237TC0.00771ICMT-TRUEAluSzSINE,Alu
chr3179117128TC0.00112GNB4-TRUEAluSzSINE,Alu
chr115896199GA0.00483DNAJC16+FALSEAluSpSINE,Alu
chr1179876988CG0.00047TOR1AIP1+FALSE
chr4184238324GA0.00870WWC2+FALSE
chr1765335430TC0.00019PSMD12-TRUEAluSxSINE,Alu
chr489181451TC8.32748E-05PPM1K-TRUEAluSx1SINE,Alu
chr101086797AC0.00499IDI2-AS1,IDI1+,-FALSE
chr142884086GT0.00040RIMKLA+FALSE
chr111347150CA0.00366UBIAD1+FALSE
chr177759578AG0.00492AK5+FALSE
chr357613144TC0.00959DENND6A,PDE12+,-FALSEAluSzSINE,Alu
chr1765334767TC3.33546E-08PSMD12-TRUEAluSqSINE,Alu
chr16283296TC0.00122ICMT-TRUEAluSx3SINE,Alu
chr153289547AG0.00646ZYG11B+TRUEAluSzSINE,Alu
chr194702991GC0.00397ARHGAP29-FALSE
chr514510067GT0.00130TRIO+FALSE
chr349396588TC0.00239RHOA-FALSE
chr4139980667GT0.00396ELF2-FALSE
chr133324136TC0.00739S100PBP+FALSE
chr5118729619AG0.00586TNFAIP8+FALSE
chr1225974592TG2.09928E-05SRP9+FALSEAluJrSINE,Alu
chrX102613351AG0.00969TCEAL9+FALSEL1ME4aSINE,Alu
chr299812465AG0.00367MRPL30+TRUEAluSxSINE,Alu
chr1218617066AT0.00036TGFB2-OT1,TGFB2+FALSE
chr124022912GA4.29449E-05RPL11+FALSE
chr1160967890TC0.00871F11R-TRUEAluSpSINE,Alu
chr755433884AC0.00723LANCL2+FALSE
chr2110373919GA0.00669SOWAHC+FALSE
chr19989022AG0.00616LZIC-FALSEL1MB5SINE,Alu
chr2183643241CA0.00108DNAJC10+FALSE
chr629910581CA6.62336E-05.FALSE
chr165298625GA0.00761RAVER2+FALSEX12_DNASINE,Alu
chr136067760TC0.00032PSMB2-TRUEAluSzSINE,Alu
chr119953130TA0.00595MINOS1,MINOS1-NBL1+FALSE
chr12120898998AG0.00081GATC+TRUEAluJrSINE,Alu
chr116889014CT0.00722NBPF1-FALSE
chr1100549715TA0.00765SASS6-FALSE
chr1811852628CT0.00048GNAL,CHMP1B+FALSE
chr189447720GA0.00029KYAT3,RBMXL1-FALSE
chr1145512024AG0.00392NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr11595074TC0.00296CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr128859264TG0.00030RCC1+FALSE
chr1145281543CT0.00028NBPF20,NOTCH2NL+FALSE
chr110519064TC0.00012.FALSEAluSx3SINE,Alu
chr152266242GA0.00528NRDC-FALSE
chr110519951TC0.00378.FALSEAluJrSINE,Alu
chr42940085TC0.00801NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr128662254AG0.00290MED18+TRUEAluSq2SINE,Alu
chr1155695998AG0.00078DAP3+TRUEAluSpSINE,Alu
chr177482325TA5.04428E-06.FALSE
chr119585771AG0.00029MRTO4+FALSEAluSc8SINE,Alu
chr349395757GA3.97123E-06GPX1-FALSE
chr674346347AG4.16931E-07SLC17A5-FALSE
chr1145513090AG0.00017NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1145291217CT0.00415NBPF20+FALSE
chr1737006214TC0.00706.FALSEAluSxSINE,Alu
chr9125887702CT0.00019STRBP-FALSE
chr3129286413GC2.51503E-06PLXND1-FALSE
chrX3523058AC0.00019PRKX-FALSE(AC)nSINE,Alu
chr488059664TG0.00178AFF1+FALSE(GT)nSINE,Alu
chr1064911911AG0.00908NRBF2+FALSE
chr146076543AG0.00989NASP+TRUEAluSxSINE,Alu
chr237334139TC0.00146EIF2AK2-TRUEAluSzSINE,Alu
chr342253664CT0.00065TRAK1+FALSE
chr128661576AG0.00625MED18+TRUEAluSgSINE,Alu
chr1149783886CT0.00526HIST2H2BF-FALSE
chr3183900836GA0.00658AP2M1+FALSE
chr613788387TC0.00240MCUR1-TRUEAluSxSINE,Alu
chr124296869GT0.00505.FALSEAluSgSINE,Alu
chr193803622TC0.00096CCDC18-AS1-TRUEAluJrSINE,Alu
chr344772983CT0.00795ZNF501+FALSE
chr5125961918GA0.00421PHAX+FALSEFLAM_CSINE,Alu
chr13546136AG2.71404E-05TPRG1L+FALSEAluSzSINE,Alu
chr136067925TC3.39837E-06PSMB2-TRUEAluSzSINE,Alu
chr314986133TC1.90274E-11FGD5-AS1-TRUEFLAM_CSINE,Alu
chr1120267061CA0.00181PHGDH+FALSE
chr126608019TA3.63623E-05.FALSE
chr1154557171GA0.00329ADAR-FALSEA-richSINE,Alu
chr919376252AT0.00367.FALSE
chr315113716TC2.87067E-10RBSN-TRUEAluSz6SINE,Alu
chr10101992425TC0.00406CWF19L1-TRUEAluSq2SINE,Alu
chr11595586TC0.00096CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr146075188CA0.00199NASP+FALSEA-richSINE,Alu
chr2035521048AT0.00727TLDC2,SAMHD1+,-FALSE
chr132681795CT0.00791DCDC2B,TMEM234+,-FALSE
chr2105964472CT0.00398C2orf49+FALSE(TTTCTCC)nSINE,Alu
chr991724517CT0.00289SHC3-FALSE
chr1179326882AG1.03454E-05SOAT1+TRUEAluJoSINE,Alu
chr170718271GA0.00273.FALSE
chr2239360542CA0.00989ASB1+FALSE
chr1249745431AG0.00033DNAJC22+TRUEAluSx3SINE,Alu
chr1819445881TA0.00224MIB1+FALSE
chr1549419124TC1.84263E-05COPS2-TRUEMARNASINE,Alu
chr154412181TC0.00524LRRC42+FALSE
chr1153920564AG0.00323CRTC2-FALSE
chr8100890376GT0.00920COX6C-FALSE
chr1109475629AG0.00305GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr830536146TC1.15312E-06GSR-TRUEAluJrSINE,Alu
chr5178293266GA0.00924ZNF354B+FALSE
chr642856176AG0.00202RPL7L1+TRUEAluSzSINE,Alu
chr5151041877CA1.29615E-05SPARC-FALSE
chr344791553TC0.00298KIAA1143-TRUEAluJrSINE,Alu
chr1179070646TC0.00283ABL2-TRUEAluSzSINE,Alu
chr4128756632AG0.00602.FALSEAluSxSINE,Alu
chr312624321AG2.86985E-06MKRN2+FALSE
chr417802919TC0.00857DCAF16-TRUEAluSzSINE,Alu
chr1549454018CT0.00053GALK2+FALSEAluSx1SINE,Alu
chr110519888TC0.00666.FALSEAluJrSINE,Alu
chr1945406537TC0.00278TOMM40+FALSE
chrM9756GA0.00315.FALSE
chr128662053GA0.00158MED18+FALSEAluSq2SINE,Alu
chr1113240711GA0.00454MOV10+FALSE
chr1773886249TC0.00069TRIM65-TRUEFRAMSINE,Alu
chr352237970CT0.00017ALAS1+FALSE
chr2010036845AG0.00110SNAP25-AS1,ANKEF1+,-FALSE
chr116927369CT0.00943NBPF1-FALSE
chr2220037666AG0.00796CNPPD1-FALSE
chr1109818160TG0.00745CELSR2+FALSE
chr139470978TA0.00378AKIRIN1+FALSEAluSx1SINE,Alu
chr110517688TC0.00020.FALSEAluSx1SINE,Alu
chr647592459AG0.00789CD2AP+FALSE
chr1207250570AG0.00486PFKFB2+FALSE
chr1214524566TC0.00040PTPN14-TRUEAluSgSINE,Alu
chr2035410314TC0.00602SOGA1-TRUEAluSzSINE,Alu
chr284670484TC0.00324SUCLG1-TRUE
chr5175811093AG0.00730NOP16-FALSE
chr128826118AG0.00039PHACTR4+TRUEAluJbSINE,Alu
chr35259480TA5.79324E-05EDEM1+FALSE
chr3152555188GT0.00016P2RY1+FALSE
chr347036756CG0.00091NBEAL2+FALSE
chr1134370TC0.00327.FALSEAluSgSINE,Alu
chr110517526TC0.00364.FALSEAluSx1SINE,Alu
chr442091668AG0.00430.FALSEAluSpSINE,Alu
chr120978457TC0.00036PINK1-AS,DDOST-TRUEAluYSINE,Alu
chr1160175191AC0.00509LOC729867,PEA15+,-FALSE(GGC)nSINE,Alu
chr738764358TC0.00675VPS41-TRUEAluSpSINE,Alu
chr136067760TC0.00052PSMB2-TRUEAluSzSINE,Alu
chr16585215CT0.00286NOL9-FALSEFAMSINE,Alu
chr16282224TC0.00062ICMT-TRUEAluSzSINE,Alu
chr1563616881GA0.00026CA12-FALSE
chr1148556087GC0.00106.FALSE
chr198005999TC0.00027TIMM44-FALSE
chr1232532499AT0.00119.FALSE
chr1022824829TC0.00207PIP4K2A-FALSE
chr2217129526AG0.00485TPTEP1+TRUEAluSzSINE,Alu
chr23597974TC1.93309E-05RNASEH1-FALSE
chr246852033AG0.00543CRIPT+FALSE
chr1327407AG3.55459E-07.FALSE
chr5125961611AG0.00113PHAX+TRUEAluSz6SINE,Alu
chr16283306TC0.00047ICMT-TRUEAluSx3SINE,Alu
chr5145666114GT0.00766RBM27+FALSE
chr150883798TC0.00156DMRTA2-FALSE
chr133148210AG0.00778SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1153617973AG4.00129E-07CHTOP+FALSE
chr16282371TC0.00013ICMT-TRUEAluSzSINE,Alu
chr135649804CA0.00127SFPQ-FALSE
chr5125961455AG0.00029PHAX+TRUEAluSz6SINE,Alu
chr4185309396GA0.00199IRF2-FALSE(GGGAT)nSINE,Alu
chr110520331CT2.36721E-05.FALSEAluSx1SINE,Alu
chr191457883CG2.74690E-05APC2+FALSE
chr495173779TC0.00771SMARCAD1+FALSE
chr128835847AG5.60567E-05SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr1495572111AC0.00409DICER1-FALSE
chrX123045405AG0.00551XIAP+TRUEAluJoSINE,Alu
chr644417182AG0.00018CDC5L+TRUEFLAM_CSINE,Alu
chr1180167090CT0.00607QSOX1+FALSE
chr352084404AT0.00032DUSP7-FALSE(A)nSINE,Alu
chr223926233CT0.00907KLHL29+FALSE
chr159148136TC0.00244MYSM1-FALSE
chr1675479467TC0.00160TMEM170A-TRUEAluJbSINE,Alu
chr1531231255AG0.00027FAN1,MTMR10+,-FALSE
chr116932429CG0.00106NBPF1-FALSEL1MC2SINE,Alu
chr298409998GT0.00261TMEM131-FALSE
chr671299074AG0.00824.FALSEAluSx1SINE,Alu
chr1161488017TC5.55712E-05FCGR2A+FALSEMER57FSINE,Alu
chr145976722GT0.00292MMACHC,PRDX1+,-FALSE
chr4188925184GA0.00032ZFP42+FALSE
chr195658358TC0.00633TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr587566382TA0.00997TMEM161B-AS1+FALSE
chr1155161736GA0.00088MUC1-FALSE
chr116933753GA0.00609NBPF1-FALSEGA-richSINE,Alu
chr133148706AG0.00087SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr1201845882GA0.00890IPO9+FALSE
chr1120166681GA0.00241ZNF697-FALSE
chr153679610GA0.00084CPT2+FALSEAluSzSINE,Alu
chr345960578GA0.00632FYCO1-FALSE
chr344791355TC0.00468KIAA1143-TRUEAluJrSINE,Alu
chr1681064560AG0.00014CENPN+TRUEAluSgSINE,Alu
chr116889413TC0.00016NBPF1-TRUEL1MC4SINE,Alu
chr353265957TC0.00493TKT-FALSE
chr116945027TC2.31134E-07CROCCP2-FALSEL1ME3CzSINE,Alu
chr7100279138AT0.00741GIGYF1-FALSEA-richSINE,Alu
chr579923788TC0.00693DHFR-TRUEAluSpSINE,Alu
chr633384326AT0.00678.FALSE
chr3172224303AG0.00524TNFSF10-FALSE
chr192946618AG0.00062GFI1-FALSE
chr131346203AC0.00050SDC3-FALSE
chr3155660961AG6.62819E-05.FALSEAluSzSINE,Alu
chr7300512GA3.09252E-06FAM20C+FALSE
chr11152309AT0.00035SDF4-FALSE
chr9131872860CT0.00141CRAT-FALSE
chr1120695049GA0.00129.FALSE
chr625986717AG0.00217TRIM38+TRUEAluJbSINE,Alu

Differential Expression Gene Analysis