Dataset Overview
RBPWDR3
Knock-MethodshRNA
RBP FamilyUtp12
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR334BTA
PlatformHiSeq
Pubmed ID32252787

WDR3 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of WDR3
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of WDR3


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr126801762GT0.00762HMGN2+FALSE
chr1168523472TC0.00649CPT1A-TRUEAluSqSINE,Alu
chr7102004748TC0.00050LOC100289561,LOC100630923+FALSE
chr1144615138TG0.00196NBPF20,NBPF9+FALSE
chr135319550CT0.00781SMIM12-FALSEAluSgSINE,Alu
chr237328034TC0.00047.FALSE
chr3179306775CT7.88487E-06MRPL47-FALSE
chr1184761350TC0.00754FAM129A-TRUEAluJoSINE,Alu
chr2128601583TC0.00550.FALSEAluJrSINE,Alu
chr1144917841TC4.47769E-05NBPF20,PDE4DIP+,-FALSE
chr919376246AT0.00298.FALSE
chr285776987TA0.00059GGCX-FALSE
chr349460407CT0.00080NICN1-FALSEL2cSINE,Alu
chr189518173TA0.00465GBP1-FALSE
chr3184039666AG0.00010EIF4G1+FALSE
chr146830430GA0.00023NSUN4+FALSELTR108a_MamSINE,Alu
chr1114438951AG0.00017AP4B1-AS1,AP4B1+,-FALSE
chrX54587218AG0.00014GNL3L+TRUEAluSq2SINE,Alu
chr1731258352GA0.00417TMEM98+FALSE
chr1117645998AG0.00057.FALSE
chr116933642GA0.00679NBPF1-FALSEGA-richSINE,Alu
chr617557416GT0.00885CAP2+FALSE
chr4154257511CA0.00093TRIM2+FALSE(A)nSINE,Alu
chr339137794TC0.00240WDR48+FALSE
chr3141879810TC0.00348GK5-FALSEAluJrSINE,Alu
chr110042955AG0.00430NMNAT1+TRUEAluScSINE,Alu
chr1585185502TC0.00058WDR73,SCAND2P+,-FALSEAluScSINE,Alu
chr838829839AG0.00184PLEKHA2+TRUEAluJr4SINE,Alu
chr237429733AG0.00381CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr2035409827TC0.00267SOGA1-TRUEAluSxSINE,Alu
chr3194361768CT1.49766E-06LSG1-FALSEMSTASINE,Alu
chr2143638998GA0.00496KYNU+FALSE
chr1190234133AC5.13910E-06BRINP3-FALSE
chr9133579674AG0.00018EXOSC2+TRUEAluSx3SINE,Alu
chr47765042CT0.00903AFAP1,AFAP1-AS1+,-FALSE
chr1169101269TG0.00207ATP1B1+FALSE(T)nSINE,Alu
chr537290554TC7.20052E-07.FALSEAluSzSINE,Alu
chr895804469AG0.00133DPY19L4+TRUEAluSq2SINE,Alu
chr5174956497CT0.00487SFXN1+FALSE
chr7100279005CA0.00176GIGYF1-FALSE(A)nSINE,Alu
chr1611445552TC0.00533RMI2+FALSE
chr1758156064GA9.79781E-05HEATR6-FALSE
chr1145281633CA0.00510NBPF20,NOTCH2NL+FALSE
chr5135513089TA7.47633E-06SMAD5+FALSE
chr1112170157CG0.00335RAP1A+FALSEL1ME4aSINE,Alu
chr3160213318TG0.00215KPNA4-FALSE
chr12125511404AG0.00201THRIL-FALSEAluSx1SINE,Alu
chr323958355CT0.00997NKIRAS1,RPL15+,-FALSE
chr7156764350GC0.00415NOM1+FALSE
chr729962586GA0.00051SCRN1-FALSE
chr3185009713GT0.00106MAP3K13+FALSE
chr3138121198CT0.00076MRAS+FALSE
chr145976220AG0.00031MMACHC+TRUE
chr1121115958TC0.00860SRGAP2-AS1,SRGAP2D,SRGAP2B,SRGAP2C+,-FALSE
chr8141530799GA0.00525.FALSE
chr128835937AG0.00121SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr1146740502CG0.00692CHD1L+FALSE
chr3101579158AG0.00022NFKBIZ+FALSEAluJoSINE,Alu
chr312942851CG0.00013IQSEC1-FALSE
chr417803604TC0.00174DCAF16-TRUEAluYSINE,Alu
chr16282401TC0.00026ICMT-TRUEAluSzSINE,Alu
chr140147856TC0.00205HPCAL4-TRUE
chr1154320942AG0.00579ATP8B2+FALSE
chr7138265310AG0.00121TRIM24+FALSE
chr1924103987AG1.84513E-07ZNF726+TRUEAluSg4SINE,Alu
chr840011786CA0.00196C8orf4+FALSE
chr122854702CT4.66415E-11ZBTB40+FALSE
chr1156613401TC5.47226E-05BCAN+FALSE
chr439550715TC0.00995UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr155619569CT0.00477USP24-FALSE
chr12125511226AG0.00205THRIL-FALSEAluSx1SINE,Alu
chr165692499CT0.00516AK4+FALSE(T)nSINE,Alu
chr6150045926TC0.00053NUP43-TRUEAluSqSINE,Alu
chr4190878580AG0.00097FRG1+FALSE
chr197543764CT0.00901DPYD-FALSE
chr4160280309GT0.00770RAPGEF2+FALSE(T)nSINE,Alu
chr345267450CG0.00036TMEM158-FALSE
chr16283273TC0.00109ICMT-TRUEAluSx3SINE,Alu
chr2231744347AG0.00113LINC01521+TRUEAluSpSINE,Alu
chr1900717CT0.00661KLHL17+FALSE(TTTA)nSINE,Alu
chr177759578AG0.00955AK5+FALSE
chr128826150AG0.00052PHACTR4+TRUEAluJbSINE,Alu
chr5159492103TG0.00332TTC1+FALSE
chr1148556726GT0.00023.FALSE
chr1150548883AC0.00255MCL1-FALSE
chr237328075TC0.00863.FALSE
chr41193026AG0.00471SPON2,LOC100130872-FALSEAluSpSINE,Alu
chr126898378CA0.00148RPS6KA1+FALSE
chr1921367098AG0.00147ZNF431+TRUEAluScSINE,Alu
chr286252038TC0.00931POLR1A-TRUEAluSq2SINE,Alu
chr1760522243CG0.00327METTL2A+FALSE
chr9131872852GC0.00064CRAT-FALSE
chr1145512937AG1.47906E-06NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1145289875TC0.00160NBPF20+FALSEMIRSINE,Alu
chr133148736AG0.00525SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr417626174TA0.00534MED28+FALSE
chr318427924GT0.00312SATB1-FALSE
chr116929327CT0.00304NBPF1-FALSEERVL-E-intSINE,Alu
chr1073994170AG0.00218ANAPC16+TRUEAluJrSINE,Alu
chr1117645998AG0.00057.FALSE
chr1160967754TC0.00563F11R-TRUE(T)nSINE,Alu
chr7107789927TC0.00111NRCAM-FALSE
chr119586519AG0.00015MRTO4+TRUEAluSzSINE,Alu
chr224223256AG0.00711UBXN2A+TRUEAluScSINE,Alu
chr8128752643GA4.26326E-14MYC+FALSEGA-richSINE,Alu
chr9132268259AG0.00032LINC00963+TRUEAluJbSINE,Alu
chr861655619CT0.00475CHD7+FALSE
chr1013687171TC0.00033FRMD4A-FALSE
chr1148251083TC0.00041NBPF8,NBPF14,NBPF9-FALSEL1MC4SINE,Alu
chr581571877CT0.00033RPS23-FALSE
chr274645427AG0.00011C2orf81-FALSE
chr153290298AG0.00258ZYG11B+TRUEAluSg4SINE,Alu
chr125717365CG0.00229RHCE-FALSE
chr2162849312GC0.00840DPP4-FALSE
chr128662253AG0.00187MED18+TRUEAluSq2SINE,Alu
chr185647107TC0.00255SYDE2-TRUEAluSxSINE,Alu
chr315112630CT0.00017RBSN-FALSEAluSq2SINE,Alu
chr297534237CT0.00644SEMA4C-FALSE
chr47764017TC0.00028AFAP1,AFAP1-AS1+,-FALSE
chr2128950497AG4.96654E-06UGGT1+TRUEAluScSINE,Alu
chr128825337AG0.00904PHACTR4+TRUEAluSgSINE,Alu
chr124022914AG0.00347RPL11+FALSE
chr1116234313AG0.00016VANGL1+FALSE
chr115755248CT0.00405EFHD2+FALSE
chr129519595TC0.00208MECR-TRUEAluJbSINE,Alu
chr29629305AT0.00591ADAM17-FALSE
chr2210885022CT0.00325RPE+FALSE
chr140537922AG0.00686CAP1+FALSE(A)nSINE,Alu
chr644417182AG0.00018CDC5L+TRUEFLAM_CSINE,Alu
chr799636950AG0.00927ZKSCAN1+FALSEAluSx1SINE,Alu
chr116112795AG4.56234E-06FBLIM1+FALSE
chr5125962176AG0.00020PHAX+TRUEAluScSINE,Alu
chr12120898658AG0.00372GATC+TRUEAluYSINE,Alu
chr7100031495CT0.00475MEPCE+FALSE
chr9128729385CA0.00170PBX3+FALSE
chr3196670087GA4.07177E-06NCBP2-AS2+FALSE
chr1953999034AG0.00282.FALSEAluSq2SINE,Alu
chr136531942AG0.00042.FALSEAluSq2SINE,Alu
chr190478690AC0.00035ZNF326+FALSE
chr337366459CA2.94197E-05GOLGA4+FALSE
chr5125961447AG0.00563PHAX+TRUEAluSz6SINE,Alu
chr344791062TC0.00035KIAA1143-FALSE
chr1206557430CT0.00011SRGAP2+FALSE
chr564964623TC1.14652E-05SGTB-TRUEAluSx1SINE,Alu
chr1204521160AG0.00231MDM4+TRUEAluSpSINE,Alu
chr128826223AG0.00990PHACTR4+TRUEAluJbSINE,Alu
chr5149363414AG0.00503SLC26A2+TRUEAluJrSINE,Alu
chr19161199TC0.00468.FALSEAluSxSINE,Alu
chr237327666TC0.00231.FALSE
chr1210006603CT0.00829DIEXF+FALSE
chr314239845GA0.00375LSM3+FALSE
chr1109746745AG0.00073KIAA1324+TRUEAluJbSINE,Alu
chr199672919TC0.00097.FALSEAluSx3SINE,Alu
chr19416574AG0.00144SPSB1+FALSE
chr337407769AT0.00406GOLGA4+FALSE
chr830536015TC0.00286GSR-TRUEAluJrSINE,Alu
chr1180247474TC0.00022.FALSE
chr110093749TC0.00521UBE4B+FALSE
chr471682381TC0.00037GRSF1-TRUEAluSz6SINE,Alu
chr537290416TC0.00162.FALSEAluSzSINE,Alu
chr1154554947TG0.00511ADAR-FALSE
chr132631809CT2.91083E-08KPNA6+FALSE
chr1120612154CG0.00803NOTCH2-FALSE
chr117739586GA0.00093RCC2-FALSE
chr310168802AG6.92223E-05BRK1+FALSE
chr237330487TC0.00242.FALSEAluSq2SINE,Alu
chr237331525TC0.00479.FALSEAluJbSINE,Alu
chr1145112414TC0.00079NBPF20,SEC22B+FALSE
chr1224380498AG6.58460E-05DEGS1+TRUEAluSxSINE,Alu
chr2043707842AG0.00100STK4+TRUEAluJbSINE,Alu
chr1162299945AC0.00314AHNAK-FALSE
chr237330144TG0.00478.FALSE
chr229135468CG0.00217WDR43+FALSE
chr3195411267AG1.93837E-05SDHAP2+FALSE
chr111847346GC0.00547C1orf167,MTHFR+,-FALSE
chr153365235GC0.00029ECHDC2-FALSE
chr1451387782CT0.00802PYGL-FALSE
chr237328016TC5.08368E-07.FALSE
chr1145369589TC0.00128NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr136770045TC0.00488THRAP3+FALSE
chr3179042910AG0.00061ZNF639+TRUEAluSpSINE,Alu
chr126755455AG0.00342LIN28A+TRUEAluScSINE,Alu
chr9115447580TC2.95057E-05INIP-TRUEAluJbSINE,Alu
chr299813015AG0.00235MRPL30+TRUEAluJbSINE,Alu
chr153366673AG0.00243ECHDC2-FALSEAluJbSINE,Alu
chr3197611291AG0.00095.FALSEAluSx1SINE,Alu
chr1203277242TC0.00023BTG2+FALSE
chr19163334TC0.00632.FALSEAluSpSINE,Alu
chr1436784095CT0.00866MBIP-FALSE
chr1200522059AT0.00163KIF14-FALSEAluSgSINE,Alu
chr170833400CT0.00224HHLA3+FALSELTR7SINE,Alu
chr185785550CA0.00134DDAH1-FALSE
chr1828571649AT0.00301DSC3-FALSEMER65CSINE,Alu
chr1148023637CT0.00014NBPF8-FALSE
chr1168218504TC0.00748.FALSEAluSzSINE,Alu
chr110519947TC0.00184.FALSEAluJrSINE,Alu
chr12133298917AG0.00612PGAM5+TRUEAluSgSINE,Alu
chr1919791273AG0.00121ZNF101+TRUEAluSq2SINE,Alu
chr5149363414AG0.00458SLC26A2+TRUEAluJrSINE,Alu
chrX123046306AG0.00016XIAP+TRUEAluJbSINE,Alu
chr199673107TC1.71894E-07.FALSEAluSx3SINE,Alu
chr11469546GA0.00331ATAD3A+FALSE
chr11717439TA0.00663GNB1-FALSE
chr8143739435CT7.32829E-06JRK-FALSE
chr1144821888CG0.00093NBPF20,NBPF9+FALSE
chr136322433GA0.00663AGO4+FALSE
chr1269237558AG0.00034MDM2+TRUE
chr110521200TC0.00013DFFA-TRUEAluYSINE,Alu
chr1179042616AG1.60543E-05FAM20B+TRUEAluSx1SINE,Alu
chrX131339006TA0.00405RAP2C-FALSE
chr310285030GA0.00384IRAK2+FALSE
chr333907945AG3.34896E-07PDCD6IP+FALSE
chr19160989TC0.00183.FALSEAluJbSINE,Alu
chr2236677549CT0.00040MYH9-FALSE
chr1175526481CA0.00995UVRAG+FALSE
chr3183890868AG5.00274E-08DVL3+FALSEL2SINE,Alu
chr299812289AG0.00040MRPL30+TRUEAluSxSINE,Alu
chr1179044174AG0.00410FAM20B+TRUEAluSxSINE,Alu
chr2242615532CA0.00603DTYMK-FALSE
chr1229762054TA0.00535URB2+FALSE
chr3196079280TC0.00614.FALSEAluSxSINE,Alu
chr111347155CT0.00273UBIAD1+FALSE
chr1145512098AG0.00707NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr153288924AG1.39497E-05ZYG11B+TRUEAluJoSINE,Alu
chr1156564754AG0.00562GPATCH4-FALSE
chr127874481CA0.00046AHDC1-FALSE
chr285132775CG7.25564E-06TMSB10+FALSE
chr1773885274TC0.00143TRIM65-TRUEAluSgSINE,Alu
chr110517659TC0.00012.FALSEAluSx1SINE,Alu
chr110519936TC0.00607.FALSEAluJrSINE,Alu
chr1214524566TC0.00040PTPN14-TRUEAluSgSINE,Alu
chr624720271TG0.00839.FALSE
chr136770073AT4.33965E-05THRAP3+FALSE
chr122159774GA0.00257HSPG2-FALSE
chr1207943385AG0.00558CD46+TRUEAluSx1SINE,Alu
chr116889414TC0.00858NBPF1-TRUEL1MC4SINE,Alu
chr2025428348AG0.00121GINS1+TRUEAluSzSINE,Alu
chr1117645998AG0.00434.FALSE
chr314986447TC2.03372E-08FGD5-AS1-TRUEAluSq2SINE,Alu
chr193603177TC0.00364MTF2+FALSE
chr1153643449GC0.00704ILF2-FALSE
chr1144931101GA0.00358NBPF20,PDE4DIP+,-FALSE
chr285621889CT0.00366CAPG-FALSE
chr2206987205TC0.00039.FALSEAluSxSINE,Alu
chr1109856391GC0.00569SORT1-FALSE
chr145975269AG0.00098MMACHC+TRUEAluSg7SINE,Alu
chr138423199AT0.00192SF3A3-FALSEAluJoSINE,Alu
chr110517290TC0.00437.FALSEAluJrSINE,Alu
chr457326875AG0.00456PAICS+TRUEAluSx1SINE,Alu
chr310004768GA3.85967E-05EMC3-FALSETigger14aSINE,Alu
chr1583826212CT0.00278HDGFRP3-FALSE(CTT)nSINE,Alu
chr14103372469AC0.00683TRAF3+FALSE(AC)nSINE,Alu
chr1160966301TC7.77749E-07F11R-TRUEAluSgSINE,Alu
chr722983600TC0.00025FAM126A-FALSE
chr178414334CA0.00702FUBP1-FALSEA-richSINE,Alu
chr146159823TA0.00461TMEM69+FALSE
chr119238562GA3.36880E-06IFFO2-FALSE
chr729962282GC0.00023SCRN1-FALSE
chr9136209402AG0.00431MED22-FALSE(CAGGG)nSINE,Alu
chr565453894TA0.00211SREK1+FALSE
chr119542250TC0.00015LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1470838368TC0.00561SYNJ2BP-COX16,SYNJ2BP-TRUEAluSgSINE,Alu
chr119542239TC0.00038LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr2204055625GA0.00426NBEAL1+FALSE
chr110521126TC0.00560DFFA-TRUEAluYSINE,Alu
chr1256510707GA0.00056RPL41+FALSE
chr6160211652CG0.00719MRPL18+FALSE
chr238971644TG0.00021SRSF7-FALSE
chr1144930940TC0.00181NBPF20,PDE4DIP+,-FALSE
chr1861565062CG0.00207SERPINB2+FALSE
chr136068275TC0.00098PSMB2-TRUEAluScSINE,Alu
chr5171533782TC0.00039STK10-FALSE
chr1214529247TC0.00233PTPN14-TRUE
chr1154323558AT0.00011ATP8B2+FALSE
chr1256215099TA0.00227DNAJC14-FALSE
chr1173863209GA0.00156.FALSE
chr2198368112GA0.00127HSPE1,HSPE1-MOB4+FALSE
chr1225678219TC0.00080ENAH-TRUEAluSxSINE,Alu
chr697592897AC0.00144MMS22L-FALSE
chr16948076CT0.00221CAMTA1+FALSEL2aSINE,Alu
chr28996326CT0.00077MBOAT2-FALSE
chr439552148TC0.00011UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr128661656AG0.00319MED18+TRUEAluSgSINE,Alu
chr1610625108TC7.88488E-10EMP2-TRUEAluSx3SINE,Alu
chr150906945CT0.00178FAF1-FALSE
chr133149486AG0.00528SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr126161108AC7.55238E-06AUNIP-FALSEAluSc8SINE,Alu
chr2101622888TA0.00210RPL31+FALSE
chr7158536267TC0.00298ESYT2-FALSE
chr136067838TC2.61513E-05PSMB2-TRUEAluSzSINE,Alu
chr4187628395TA0.00000FAT1-FALSE
chr12121118CT0.00234FAAP20-FALSE
chr18045341TA0.00750PARK7+FALSE
chr9130209956AT0.00221RPL12-FALSE
chr841399823AG0.00172LOC102723729,GINS4+,-FALSEAluSx3SINE,Alu
chr9137330711TA0.00194RXRA+FALSE(GCTG)nSINE,Alu
chr9115447533TC0.00326INIP-TRUEAluJbSINE,Alu
chr439550558TC0.00441UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr3119545349TC0.00805GSK3B-FALSE
chr2025428646AG9.98122E-05GINS1+TRUEAluJbSINE,Alu
chr1193054485TC0.00439TROVE2+FALSE
chr3195694465TC0.00300SDHAP1-FALSE
chr133148740AG0.00210SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr2206983267TC0.00854.FALSEAluJbSINE,Alu
chr644222158TA0.00781SLC35B2-FALSE
chr12125512534AG0.00024.FALSE
chr136388197CT0.00315AGO1+FALSE
chr1104097685CT0.00028RNPC3,AMY2B+FALSE
chr1201846630CA0.00041IPO9+FALSE(CA)nSINE,Alu
chr119566382AG0.00513LOC101927895,EMC1+,-FALSE
chr199673005TC0.00017.FALSEAluSx3SINE,Alu
chr1671681515AG0.00308PHLPP2-FALSE
chr3196729939CT0.00862MELTF,MFI2-AS1+,-FALSEG-richSINE,Alu
chr19161142TC8.95302E-05.FALSEAluSxSINE,Alu
chr237331277TC0.00366.FALSEAluSx1SINE,Alu
chr11252248AG0.00938CPSF3L-FALSEAluSxSINE,Alu
chr277745788TC0.00000LRRTM4-FALSE

Differential Expression Gene Analysis