Dataset Overview
RBPEIF4B
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR313CHR
PlatformHiSeq
Pubmed ID32252787

EIF4B - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of EIF4B
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of EIF4B


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr153289892AG0.00079ZYG11B+TRUEFRAMSINE,Alu
chr237328075TC0.00335.FALSE
chr16583036TC0.00296NOL9-TRUEAluSx4SINE,Alu
chr126143726GT0.00560SEPN1+FALSEAluSxSINE,Alu
chr439460539GA0.00323RPL9-FALSE
chr153289940AG0.00245ZYG11B+TRUEFRAMSINE,Alu
chr1229631734TC0.00611NUP133-FALSE
chr119543364TC0.00447LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1109818158CT4.51493E-05CELSR2+FALSE
chr1079800443AG0.00971RPS24+FALSE
chr1453242652TC0.00081GNPNAT1-TRUEAluJrSINE,Alu
chr115896199GA0.00483DNAJC16+FALSEAluSpSINE,Alu
chr1173862270GC0.00197.FALSEAluSz6SINE,Alu
chr116891365GA1.42078E-05NBPF1-FALSE
chr229023121GT0.00077PPP1CB+FALSE
chr4177252326AG0.00554SPCS3+TRUE
chr2054963756TC0.00476AURKA-TRUEAluSq10SINE,Alu
chr4169911126CA0.00122CBR4-FALSE
chr127202844TC0.00076.FALSEAluSq2SINE,Alu
chr3156258283TC0.00686SSR3-TRUEAluYk3SINE,Alu
chr1248539888CA0.00088PFKM+FALSE
chr136068231TC0.00582PSMB2-TRUEAluScSINE,Alu
chr12125512540AG7.43833E-09.FALSE
chr153291425AG0.00507ZYG11B+TRUEAluJrSINE,Alu
chr1148003734TC0.00015NBPF8-TRUEL1MC4SINE,Alu
chr299812464AG1.88485E-05MRPL30+TRUEAluSxSINE,Alu
chr110517485TC0.00260.FALSEAluSx1SINE,Alu
chr1251325280AG0.00370METTL7A+TRUEAluSq2SINE,Alu
chr135644504AT0.00242SFPQ-FALSE
chr310285030GA0.00384IRAK2+FALSE
chr1217804325GA0.00229GPATCH2-FALSE
chr1543767774GC0.00057TP53BP1-FALSE
chr146830447AC0.00168NSUN4+FALSELTR108a_MamSINE,Alu
chr6160101723TC0.00234SOD2-TRUEAluSzSINE,Alu
chr154692331TC0.00549SSBP3-FALSE(T)nSINE,Alu
chr315113810TC0.00201RBSN-TRUEAluSz6SINE,Alu
chr226399214GA0.00187GAREM2+FALSE
chr2202029998TA0.00350CFLAR+FALSE(TTA)nSINE,Alu
chr1183112505TC0.00525LAMC1+FALSE
chr8117858602AG0.00133RAD21-FALSE
chr119984107GA0.00963MINOS1-NBL1,NBL1+FALSE
chr1942753034AG0.00883ERF-FALSE
chr112073251GT0.00957MFN2+FALSE
chr11345002AG0.00141.FALSEAluSgSINE,Alu
chr115991645TC0.00361.FALSEAluSpSINE,Alu
chr135646125CT0.00027SFPQ-FALSE
chr16282315TC5.02629E-05ICMT-TRUEAluSzSINE,Alu
chr121100856AC0.00010HP1BP3-FALSE(AC)nSINE,Alu
chr8100890376GT0.00920COX6C-FALSE
chr3196670098TC0.00019NCBP2-AS2+FALSE
chr119543353TC0.00377LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1109474776AG0.00088GPSM2,CLCC1+,-FALSEAluSzSINE,Alu
chr1765334868TC0.00096PSMD12-TRUEAluSqSINE,Alu
chr537291504TC0.00878.FALSEAluSx3SINE,Alu
chr1204526795AG0.00199MDM4+TRUEAluSxSINE,Alu
chr3101284940TC1.85568E-05TRMT10C+FALSE
chr1765335316TC0.00296PSMD12-TRUEAluSxSINE,Alu
chr120978304TA0.00018PINK1-AS,DDOST-FALSEAluYSINE,Alu
chr7129474438CT0.00034UBE2H-FALSE
chr121101368TC0.00031HP1BP3-TRUEAluScSINE,Alu
chr1249139806GA0.00983ZNF672+FALSE
chr136067821TC1.12344E-05PSMB2-TRUEAluSzSINE,Alu
chr1155144757TC0.00758KRTCAP2-FALSETigger19bSINE,Alu
chr2208620143AG0.00605CCNYL1+TRUEEutTc1-N1SINE,Alu
chr116912099GC0.00450NBPF1-FALSE
chr980333361CT0.00382GNAQ-FALSE
chr23609064GA0.00212RNASEH1-AS1+FALSEMER33SINE,Alu
chr128929961TA0.00068TAF12-FALSE
chr1150704486TC0.00157CTSS-TRUEAluJoSINE,Alu
chr237230734CT0.00192HEATR5B-FALSE
chr154493443CA0.00872TMEM59-FALSEAluSz6SINE,Alu
chr348787219AG0.00024PRKAR2A-FALSE
chr2203744550TC0.00037.FALSEAluSx1SINE,Alu
chr477996987TC0.00240CCNI-FALSE
chr3189713205TC4.97145E-05P3H2-FALSE
chr128826023AG0.00342PHACTR4+FALSEAluJbSINE,Alu
chr161819020AT0.00258MAPK8IP3+FALSE
chr2219523584CT0.00299ZNF142-FALSE
chr1204526727AG0.00033MDM4+TRUEAluSxSINE,Alu
chr116945409TA0.00105CROCCP2-FALSE
chr2114356360GA0.00520WASH2P+FALSE
chr310191943GA2.29886E-07VHL+FALSE
chr9136897584CA0.00060BRD3-FALSEA-richSINE,Alu
chr314986138TC1.80576E-11FGD5-AS1-TRUEFLAM_CSINE,Alu
chr1184661932AG0.00063EDEM3-FALSE
chr133148045AG0.00264SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr556177849CG0.00921MAP3K1+FALSE(CAA)nSINE,Alu
chr1205577901GA0.00904ELK4-FALSE
chr4128756579AG0.00501.FALSEAluSxSINE,Alu
chr1142449GA0.00073.FALSEMIRbSINE,Alu
chr2132278176TG0.00291LOC150776+FALSE
chr159121768GC0.00196MYSM1-FALSE
chr165147002CT6.62669E-07CACHD1+FALSE
chr132801724TG0.00816MARCKSL1-FALSE
chr1115299508AT0.00070CSDE1-FALSE
chr3136667405TC0.00190NCK1+FALSE
chr126143727AT0.00602SEPN1+FALSEAluSxSINE,Alu
chr1765334856TC1.38810E-06PSMD12-TRUEAluSqSINE,Alu
chr1571124666CA4.50846E-10LARP6-FALSE
chr110520117TC0.00078.FALSEAluSxSINE,Alu
chr165720330AC0.00211.FALSE
chr187213182AT0.00072SH3GLB1+FALSE
chr217897488TC0.00430SMC6-FALSE
chr12133298937AG0.00240PGAM5+TRUEAluSgSINE,Alu
chr310193796AG2.82806E-06VHL+TRUEAluSxSINE,Alu
chr115909850CG0.00660AGMAT-FALSE
chr348485452TA0.00363TMA7+FALSE
chr1120162442TC0.00065ZNF697-FALSE
chr227887286GA0.00404SLC4A1AP+FALSE
chr116890331CG0.00226NBPF1-FALSE
chr117085028GA0.00803MST1L,LOC102724562-FALSE
chr19162224TC0.00523.FALSEAluSxSINE,Alu
chr132372358CT0.00303PTP4A2-FALSE(CA)nSINE,Alu
chr613788387TC0.00240MCUR1-TRUEAluSxSINE,Alu
chr2238285016AG0.00030.FALSEAluSzSINE,Alu
chr127992824GA0.00503IFI6-FALSE
chr146828700AG0.00093NSUN4+FALSE
chr12124105948CT0.00778EIF2B1-FALSE
chr1249745500AG0.00265DNAJC22+TRUEAluSx3SINE,Alu
chr274442550AT0.00242.FALSE
chr140538317CA0.00178CAP1+FALSE
chr3195393406CT0.00690SDHAP2+FALSE
chr1160967755CT0.00563F11R-FALSE(T)nSINE,Alu
chr11252309AT0.00403CPSF3L-FALSEAluSxSINE,Alu
chr1143135057GA0.00403LOC102723769-FALSE
chr116534255CG0.00980ARHGEF19-FALSE
chr3196670086TG1.91816E-05NCBP2-AS2+FALSE
chr2121979980GA0.00525TFCP2L1-FALSEL1MB8SINE,Alu
chr4110635488GT8.00508E-05PLA2G12A-FALSE
chr9136209397GC0.00709MED22-FALSE
chr1233514975GT0.00584MLK4+FALSE
chr3100083460GA0.00041TOMM70-FALSEFAMSINE,Alu
chr3194349178CT0.00881TMEM44-FALSE
chr1100150196AG0.00176PALMD+TRUEAluJrSINE,Alu
chr237076594TC0.00198STRN-FALSE
chr1145513016AG0.00400NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr352289709GC4.88711E-11WDR82-FALSEMIRSINE,Alu
chr1160966351TC4.07282E-11F11R-TRUEAluSgSINE,Alu
chr3194789663TC0.00754XXYLT1-FALSEMARNASINE,Alu
chr1168524809TC0.00129CPT1A-TRUE
chr128836975AG0.00782SNHG3,RCC1+TRUEAluScSINE,Alu
chr1183213770GC0.00734LAMC2+FALSE
chr4119526740CG0.00435LOC729218+FALSE
chr1145273345TC0.00640NBPF20,NOTCH2NL+FALSE
chr119543352TC0.00098LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1957802824GA0.00924ZNF460+FALSE
chr145975498AG9.09033E-05MMACHC+TRUEAluSx4SINE,Alu
chr9102744711AT0.00675ERP44-FALSE
chr119199221CT0.00095ALDH4A1-FALSE
chr187209658GA0.00219SH3GLB1+FALSE
chr1206581246TC0.00210SRGAP2+FALSE
chr119984100GC0.00563MINOS1-NBL1,NBL1+FALSE
chr1150337289GT0.00020RPRD2+FALSE
chr233623905GT0.00262LTBP1+FALSE
chr118709315AG0.00307RPL27A+TRUEAluYk2SINE,Alu
chr5125961210AG0.00966PHAX+TRUEAluSzSINE,Alu
chr1931939GA0.00428.FALSE
chr187811100AT0.00084LMO4+FALSE
chr488060832TC0.00531AFF1+FALSE
chr237329300TC0.00092.FALSEAluJr4SINE,Alu
chr217965390TC0.00713GEN1+FALSEL1M4SINE,Alu
chr133148706AG0.00087SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr1109884775TG0.00026SORT1-FALSE
chr136067811TC0.00467PSMB2-TRUEAluSzSINE,Alu
chr1108742123CG1.29742E-06SLC25A24-FALSE
chr2191556849AT0.00158NAB1+FALSE
chr4128756632AG0.00072.FALSEAluSxSINE,Alu
chr5115428334GT0.00265COMMD10+FALSE
chr122109370GA0.00371USP48-FALSE
chr3196557274CT0.00285PAK2+FALSE
chr825272425CT0.00605DOCK5+FALSE
chr120978302AT0.00038PINK1-AS,DDOST-FALSEAluYSINE,Alu
chr1148556726GT0.00023.FALSE
chr1242011534AG0.00248EXO1+FALSE
chr441673604TC0.00580LIMCH1+FALSE
chr453732381CT0.00433RASL11B+FALSE(TTTCTTT)nSINE,Alu
chr3179115635TC0.00453GNB4-TRUEAluSg7SINE,Alu
chr310192826AG0.00037VHL+TRUEAluSx1SINE,Alu
chr643747963GC0.00274VEGFA+FALSE
chr8140475147CT0.00719.FALSE
chr128825427AG0.00484PHACTR4+TRUEAluSgSINE,Alu
chr1541590972AG2.40282E-05OIP5-AS1+TRUEAluSx1SINE,Alu
chr121611798CT0.00338LINC00942+FALSE
chr2128950548AG0.00589UGGT1+TRUEAluScSINE,Alu
chr1201846617AC0.00380IPO9+FALSE(CA)nSINE,Alu
chr191037984TC0.00908CNN2+FALSE(TT)nSINE,Alu
chr191863170GA0.00204KLF16-FALSE
chr2183642652GA0.00309DNAJC10+FALSE
chr120976163CT0.00091PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr11118940957CG0.00642VPS11+FALSE
chr11650832AG0.00241CDK11B,CDK11A-FALSE
chr2201774393TC0.00971.FALSEAluSzSINE,Alu
chr9100847551GT0.00543TRIM14-FALSEMIRSINE,Alu
chr146828734TC0.00604NSUN4+FALSE
chr4170017406AT0.00534SH3RF1-FALSE
chr1112003957GA0.01000ATP5F1+FALSEHelitron2Na_MamSINE,Alu
chr43514695AG1.35580E-12LRPAP1-FALSE
chr2198368112GA0.00127HSPE1,HSPE1-MOB4+FALSE
chr1144641025GA0.00850CD82+FALSE
chr175671215CT0.00019SLC44A5-FALSE
chr126755643AG0.00728LIN28A+FALSEAluScSINE,Alu
chr119655758TA0.00044PQLC2+FALSEAluSzSINE,Alu
chr76202056GA0.00019CYTH3-FALSE
chr116933583TC0.00050NBPF1-FALSEGA-richSINE,Alu
chr29629306GT0.00255ADAM17-FALSE
chr179356400CT0.00714ADGRL4-FALSE
chr11650801TC0.00359CDK11B,CDK11A-FALSE
chr1916661483TC0.00824SLC35E1-TRUEAluSzSINE,Alu
chr146828653TA0.00920NSUN4+FALSE
chr16283306TC0.00609ICMT-TRUEAluSx3SINE,Alu
chr345722047AG0.00085LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu

Differential Expression Gene Analysis