Dataset Overview
RBPHNRNPK
Knock-MethodshRNA
RBP FamilyKH_1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR529JNJ
PlatformHiSeq
Pubmed ID32252787

HNRNPK - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of HNRNPK
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of HNRNPK


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr2103333656TA0.00488MFSD9-FALSEAluYm1SINE,Alu
chr315113799TC0.00200RBSN-TRUEAluSz6SINE,Alu
chr176229185TA0.00280ACADM+FALSE
chr3195243006CA0.00982PPP1R2-FALSE
chr1773885248TC0.00017TRIM65-TRUEAluSgSINE,Alu
chr128825418AG0.00525PHACTR4+TRUEAluSgSINE,Alu
chr3141879810TC0.00348GK5-FALSEAluJrSINE,Alu
chr1142690928CA0.00022.FALSE
chr193827764AG0.00053DR1+FALSE
chr1453242417TC0.00423GNPNAT1-TRUEAluJoSINE,Alu
chr6109784327TC0.00854MICAL1,ZBTB24-TRUEAluSgSINE,Alu
chr10104661031AG0.00265BORCS7-ASMT,AS3MT+TRUEAluYSINE,Alu
chr136068295TC0.00910PSMB2-TRUEAluScSINE,Alu
chr345721836AG0.00714LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr1203711876GA0.00444ATP2B4+FALSE
chr1289914261TC0.00135POC1B,GALNT4,POC1B-GALNT4-FALSE
chr552389815AG0.00486ITGA2+TRUE
chr346623292TC0.00408TDGF1+FALSEAluSx3SINE,Alu
chr5150869672AT0.00755SLC36A1+FALSE
chr1757281125AG0.00204PRR11+TRUEAluSzSINE,Alu
chr1156675377GC0.00935CRABP2-FALSE
chr110517513TC0.00088.FALSEAluSx1SINE,Alu
chr144447006TC0.00767B4GALT2+FALSE(CAG)nSINE,Alu
chr116889864CA0.00020NBPF1-FALSE
chr121810903AG0.00154NBPF3+FALSEL1MC4SINE,Alu
chr11110128567AT0.00634RDX-FALSE
chr117298140CG0.00584CROCC+FALSE
chr184971969GT0.00626GNG5-FALSE
chr194335330AT0.00366DNTTIP2-FALSE
chr2218571477AG4.57932E-05PEX26+TRUEAluSzSINE,Alu
chr1146650337GT0.00589PDIA3P1+FALSE
chr347386062TA4.63678E-05KLHL18+FALSE
chr110520819TC0.00022DFFA-TRUEAluSc8SINE,Alu
chr116929056CT0.00398NBPF1-FALSE
chr1766264542AT0.00110ARSG,SLC16A6+,-FALSE
chr133322929TG0.00340S100PBP+FALSEAluSpSINE,Alu
chr122148474TC0.00089LDLRAD2+FALSEMIRbSINE,Alu
chr2114352238GA8.42668E-06WASH2P+FALSE
chr1200827638AG0.00665CAMSAP2+FALSE
chr1144595943AG0.00050NBPF20+FALSEAluJbSINE,Alu
chr552393421CT0.00144MOCS2-FALSEL1MA9SINE,Alu
chr841401571TA0.00240LOC102723729,GINS4+,-FALSE
chr1062554474TG6.65730E-05CDK1+FALSE
chr46718811AG1.36854E-07BLOC1S4+FALSEFLAM_ASINE,Alu
chr123150859CT0.00317.FALSE(CCTCCCTG)nSINE,Alu
chrX54587297AG0.00759GNL3L+TRUEAluSq2SINE,Alu
chr654805688AC0.00220FAM83B+FALSE
chr19740896CT0.00078PIK3CD,PIK3CD-AS2+,-FALSEMLT1F1SINE,Alu
chr136529549AG0.00806.FALSEAluJrSINE,Alu
chr18412652AC0.00929RERE-FALSE
chr3169810030TC0.00659PHC3-TRUEAluSxSINE,Alu
chr1109746825AG0.00094KIAA1324+TRUEAluJbSINE,Alu
chr124798520AC0.00110NIPAL3+FALSE
chr189648082GA0.00074GBP4-FALSELTR2BSINE,Alu
chr2210885022CT0.00325RPE+FALSE
chr817503270GC0.00410MTUS1-FALSE
chr110517313TC0.00196.FALSEAluJrSINE,Alu
chr1913883548AG0.00566MRI1+TRUEAluYk3SINE,Alu
chr10101563815GA0.00218ABCC2+FALSE
chr1161931628GC0.00476ATF6+FALSE
chr42940485TC0.00676NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr133149400AG0.00407SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1936575645GA0.00590WDR62+FALSE
chr9132266644AG0.00081LINC00963+TRUEAluSxSINE,Alu
chr1120839681CA0.00125FAM72B+FALSE
chr1165179815CA0.00447FRMD8+FALSE
chr237328034TC0.00380.FALSE
chr145975286AG0.00200MMACHC+TRUEAluSg7SINE,Alu
chr116892276TC0.00236NBPF1-FALSE
chr1160966434TC0.00175F11R-TRUEAluSgSINE,Alu
chr145244414TA0.00456.FALSE
chr3197400501CG0.00011RUBCN-FALSE
chr168168152CT0.00258GNG12-FALSE
chr44291825CT1.35815E-09LYAR-FALSE
chr170718272AT0.00166.FALSE
chr9136209397GC0.00709MED22-FALSE
chr13730400TC0.00800CEP104-TRUEAluSx3SINE,Alu
chr11125763746CG0.00166HYLS1,PUS3+,-FALSE
chr192941357AG0.00296GFI1-FALSE
chr110518591AT0.00545.FALSE
chr339450156AG0.00985RPSA+FALSE
chr2208620129AG0.00061CCNYL1+TRUEEutTc1-N1SINE,Alu
chr417803604TC0.00174DCAF16-TRUEAluYSINE,Alu
chr349395694TC0.00074GPX1-FALSE
chr5167898510CG0.00013WWC1+FALSE
chr128825337AG0.00191PHACTR4+TRUEAluSgSINE,Alu
chr1419684445AG0.00351DUXAP10+FALSE
chr125894466AC0.00783LDLRAP1+FALSEMIRbSINE,Alu
chr1145512074AG0.00084NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr146076529AG0.00196NASP+TRUEAluSxSINE,Alu
chr144171143CA0.00118KDM4A-AS1,KDM4A+,-FALSE
chr310192720AG0.00110VHL+TRUEAluSx1SINE,Alu
chr596350710GA0.00302LNPEP+FALSE
chr468483804AT0.00720UBA6-FALSE
chr1185069687CT0.00072RNF2+FALSE
chr8144940794GC0.00038EPPK1-FALSE
chr642856959AG6.63353E-07RPL7L1+TRUEAluSpSINE,Alu
chr127876482CA0.00687AHDC1-FALSE
chr348787052TC0.00631PRKAR2A-TRUEAluSx3SINE,Alu
chr1542707317AT8.30558E-05ZNF106-FALSE
chr1625269014GC0.00235.FALSE
chr438946824CT0.00250FAM114A1+FALSE
chr2202029998TA0.00350CFLAR+FALSE(TTA)nSINE,Alu
chr185488830TC0.00137MCOLN3-TRUEAluJrSINE,Alu
chr674133914TC0.00014.FALSEAluYSINE,Alu
chrX16782947AG0.00225.FALSEAluJbSINE,Alu
chr111083183GT0.00342TARDBP+FALSE
chr135817023GC0.00547ZMYM4+FALSE
chr3194790434CG0.00705XXYLT1-FALSE
chr5150647744AG0.00036GM2A+TRUEAluScSINE,Alu
chr1144014068TC0.00118.FALSE
chr121795388AG0.00790NBPF3+FALSE
chr1143135166GT0.00325LOC102723769-FALSE
chr1145282904AG0.00542NBPF20,NOTCH2NL+FALSEL2aSINE,Alu
chr1919793168AG0.00481ZNF101+TRUEAluSzSINE,Alu
chr644417159AG0.00959CDC5L+TRUEFLAM_CSINE,Alu
chr1117531179GA0.00116PTGFRN+FALSE
chr146075661AG0.00071NASP+TRUEAluSx4SINE,Alu
chr153289547AG0.00505ZYG11B+TRUEAluSzSINE,Alu
chr126572048AG0.00410VAMP1-FALSE
chr185715978CG0.00815C1orf52-FALSE
chr2174090336AC0.00331ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr126608016GA1.44245E-06.FALSE
chr1142805281CT0.00242.FALSE
chr119542401TC0.00010LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1145512024AG0.00247NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr29629304AG0.00121ADAM17-FALSE
chr1100388748TC0.00445AGL+FALSE
chr111190646GA0.00369MTOR-FALSE
chrX106184603AT0.00717MORC4-FALSE(GA)nSINE,Alu
chr119543364TC0.00447LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr7116340269CT0.00313MET+FALSE
chr110520099TC5.82547E-06.FALSEAluSxSINE,Alu
chr1168212509AG0.00765.FALSE
chr147716042AT0.00574STIL-FALSE
chr138155698GT0.00368C1orf109-FALSEAluSx1SINE,Alu
chr12161135AG0.00028SKI+FALSE
chr11152631CA0.00517SDF4-FALSE
chr1179044216AG0.00277FAM20B+TRUEAluSxSINE,Alu
chr131905887AC0.00221SERINC2+FALSE
chr227293349CT0.00503AGBL5,OST4+,-FALSE
chr145975574AG0.00299MMACHC+TRUEAluSx4SINE,Alu
chr4128756738AG0.00408.FALSEAluSxSINE,Alu
chr128861636GA0.00754RCC1+FALSE(GCATGT)nSINE,Alu
chr344791062TC0.00124KIAA1143-FALSE
chr1181026558GA0.00217MR1+FALSE
chr7129474438CT0.00034UBE2H-FALSE
chr116890130AC0.00054NBPF1-FALSE
chr592956173CT0.00646FAM172A-FALSE
chr1110596569GA0.00867STRIP1+FALSE
chr18412989AG0.00225RERE-FALSE
chr296850885TC0.00699STARD7-FALSE
chr489181431TC5.21801E-05PPM1K-TRUEAluSx1SINE,Alu
chr132373563GA0.00089PTP4A2-FALSE
chr72767939TC0.00028AMZ1,GNA12+,-FALSE
chr537290492TC8.25709E-07.FALSEAluSzSINE,Alu
chr145975498AG0.00064MMACHC+TRUEAluSx4SINE,Alu
chr5174956487TC0.00457SFXN1+FALSE
chr250148477CT0.00741NRXN1-FALSE
chr136530674AG0.00603.FALSEAluSgSINE,Alu
chr137949806GA2.03247E-05ZC3H12A+FALSE
chr120976759CT2.31016E-05PINK1,PINK1-AS+,-FALSE
chr298388810GT6.24900E-05TMEM131-FALSE
chr540832555AT0.00347RPL37-FALSE
chr1165065373AG0.00487POLA2+TRUEAluYSINE,Alu
chr311596302TC0.00110ATG7+FALSE
chr237429532AG0.00014CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr3195694465TC0.00300SDHAP1-FALSE
chr1100440553AG0.00179SLC35A3+TRUEAluJbSINE,Alu
chr3101405563AG0.00511RPL24-FALSE
chr333186087AG1.22529E-05CRTAP+FALSELTR16A1SINE,Alu
chr642094498TC0.00931C6orf132-TRUEAluSq2SINE,Alu
chr116957414CT0.00116.FALSE
chr8144684474TC0.00058.FALSE
chr7300513TC2.92808E-06FAM20C+FALSE
chr595130804CT0.00792RHOBTB3+FALSEAluSzSINE,Alu
chr154691921GA0.00032SSBP3-FALSE
chr19161357TC0.00739.FALSEAluSxSINE,Alu
chr112677525GA0.00122DHRS3-FALSE(A)nSINE,Alu
chr133086812TC0.00250.FALSEAluYSINE,Alu
chr127052982TG0.00199C12orf57+FALSEU7SINE,Alu
chr12102517753TC0.00022PARPBP+FALSE
chr596366315TC0.00319.FALSE(TC)nSINE,Alu
chr264859679TC0.00824SERTAD2-FALSE
chr3179116220TC0.00343GNB4-TRUEAluSz6SINE,Alu
chr1541590999AG0.00049OIP5-AS1+TRUEAluSx1SINE,Alu
chr1156613632GA0.00187BCAN+FALSE
chr2172413267GC0.00938CYBRD1+FALSE
chr237331555TC0.00171.FALSEAluJbSINE,Alu
chr626095642AG0.00332.FALSEAluYSINE,Alu
chr237331025TC0.00055.FALSEAluSx1SINE,Alu
chr729963082GA0.00118SCRN1-FALSE
chr211728089CT0.00352GREB1+FALSEAluSzSINE,Alu
chr1149816373GA0.00364.FALSE(A)nSINE,Alu
chrX77083116TC0.00658MAGT1-TRUEAluSgSINE,Alu
chr223926233CT0.00907KLHL29+FALSE
chr128785597GC0.00595PHACTR4+FALSE
chr1114940216TG0.00674TRIM33-FALSE(T)nSINE,Alu
chr5132232315GA0.00573AFF4-FALSE
chr1749041692TC2.35976E-05SPAG9-TRUEAluSxSINE,Alu
chr1475202834AG7.36085E-05FCF1+TRUEAluSxSINE,Alu
chr363996262CT0.00681PSMD6-AS2,PSMD6+,-FALSE
chr9125609939AT0.00693.FALSE
chr110520683TC0.00457DFFA-TRUEAluSc8SINE,Alu
chr223865260TC0.00262KLHL29+FALSE
chr1900725TG0.00110KLHL17+FALSE(TTTA)nSINE,Alu
chr342826041TG0.00019HIGD1A-FALSE
chr1213244381GA0.00345RPS6KC1+FALSE
chr5125961447AG0.00563PHAX+TRUEAluSz6SINE,Alu
chr122357435AC0.00454LINC00339+FALSE
chr1144594373CG0.00715NBPF20+FALSE
chr1765334867TC1.03096E-06PSMD12-TRUEAluSqSINE,Alu
chr136068237TC0.00150PSMB2-TRUEAluScSINE,Alu
chr1100490067AG0.00267SLC35A3+TRUEAluSgSINE,Alu
chr237331578TC0.00675.FALSEAluJbSINE,Alu
chr674303531TC0.00487SLC17A5-TRUEAluJrSINE,Alu
chr4109734309TC0.00197COL25A1-FALSE
chr285837797TC0.00097USP39,C2orf68+,-FALSEAluSxSINE,Alu
chr11337737GC2.51903E-05MRPL20-FALSE
chr572801329TA0.00073BTF3+FALSE
chr115668319GA0.00489FHAD1+FALSE
chr4128995640GA0.00567LARP1B+FALSE
chr1230416414TG0.00360GALNT2+FALSE
chr258387000CT0.00027VRK2,FANCL+,-FALSE
chr7100739267GA0.00654.FALSEAluSxSINE,Alu
chr128826085AG0.00281PHACTR4+TRUEAluJbSINE,Alu
chr1225683161TG0.00168ENAH-FALSE(T)nSINE,Alu
chr177759578AG0.00031AK5+FALSE
chr1241794056CA0.00753OPN3,CHML-FALSE
chr11118940957CG0.00642VPS11+FALSE
chr128929961TA0.00068TAF12-FALSE
chr126796922GC0.00401DHDDS+FALSEFLAM_CSINE,Alu
chr237328008TC1.98312E-07.FALSE
chr4128756628AG0.00011.FALSEAluSxSINE,Alu
chr176252687TC0.00021RABGGTB+FALSE
chr232535836AG0.00163.FALSEAluJbSINE,Alu
chr2201774641TC0.00928.FALSEAluJr4SINE,Alu
chr1109535128GA0.00063WDR47-FALSE
chr1118166096CT0.00861FAM46C+FALSE
chr1144821900CG6.24876E-05NBPF20,NBPF9+FALSE
chr825272447AT0.00770DOCK5+FALSE
chr438946758GA0.00294FAM114A1+FALSE
chr5149361415AG0.00290SLC26A2+TRUE
chr398518155AT0.00777DCBLD2-FALSE
chr1161338504CG0.00343.FALSE
chr1269237020AG0.00378MDM2+TRUE
chr1710578246AG0.00093.FALSE
chr133148789AG0.00568SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr116890598TA0.00428NBPF1-FALSE
chr1075008845TC4.48613E-05DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr1176637680GA0.00011ACER3+FALSE
chr1534634033AG0.00939NOP10-FALSE
chr1204521625AG0.00808MDM4+TRUEAluSgSINE,Alu
chr1117617705AG0.00081TTF2+FALSE
chr1176733946AG0.00725ACER3+FALSEA-richSINE,Alu
chr1470838268TC0.00365SYNJ2BP-COX16,SYNJ2BP-TRUEAluSgSINE,Alu
chr1110566210TA0.00832AHCYL1+FALSE
chr417629377AG0.00890.FALSEAluSx3SINE,Alu
chr1225977968CT0.00490SRP9+FALSE
chr120826788AT6.12716E-05MUL1-FALSE
chr1226171400TC0.00359SDE2-TRUEBC200SINE,Alu
chr3176739404AG7.21134E-06TBL1XR1-FALSE
chr2110842200CA0.00131MALL-FALSE
chr165692499CT0.00235AK4+FALSE(T)nSINE,Alu
chr1715434181TC0.00011TVP23C-CDRT4,TVP23C-TRUEAluJbSINE,Alu
chrX150573750AT0.00887VMA21+FALSE
chr224225177AG0.00375.FALSEAluSxSINE,Alu
chr13545194CG0.00044TPRG1L+FALSE
chr3196660344TA0.00022SENP5+FALSE
chr116889639TC0.00524NBPF1-TRUE
chr3139076427CT0.00014.FALSE
chr2203741602TC0.00581.FALSEAluJrSINE,Alu
chr116889624TC0.00794NBPF1-TRUE
chr265539437CT0.00076SPRED2-FALSE
chr642849616AG0.00092RPL7L1+TRUEAluSzSINE,Alu
chr315456307TC0.00939METTL6-TRUEAluJrSINE,Alu
chr1681064533AG0.00686CENPN+TRUEAluSgSINE,Alu
chr185331816AG0.00921LPAR3-FALSE
chr110518591AT0.00169.FALSE
chr12123253851AG0.00470DENR+FALSE(AT)nSINE,Alu
chr177556766TA0.00576PIGK-FALSE
chr189225976TC0.00586PKN2+FALSE
chr457327082AG0.00834PAICS+TRUEAluSx1SINE,Alu
chr189522646GC0.00159GBP1-FALSE
chr1756081432GA4.92367E-05SRSF1-FALSE
chr45830393CT0.00220CRMP1-FALSE
chr633679439AC0.00192UQCC2-FALSE
chr1453242639TC1.43651E-05GNPNAT1-TRUEAluJrSINE,Alu
chr413604418GC2.95746E-07BOD1L1-FALSE
chr126755291AG0.00044LIN28A+TRUEAluSx1SINE,Alu
chr115993013GA1.16652E-10.FALSE
chr861534428AG0.00274RAB2A+FALSE
chr110517659TC0.00513.FALSEAluSx1SINE,Alu
chr330735330GT0.00401TGFBR2+FALSE
chr132641383CA0.00112KPNA6+FALSEAluSx3SINE,Alu
chr1200375835GT0.00063ZNF281-FALSE(T)nSINE,Alu
chr1765334758TC1.31160E-05PSMD12-TRUEAluSqSINE,Alu
chr128825337AG0.00904PHACTR4+TRUEAluSgSINE,Alu
chr5125961647AG1.53189E-07PHAX+FALSEAluSz6SINE,Alu
chr4103715820AC0.00652LOC102723704,UBE2D3+,-FALSE(A)nSINE,Alu
chr1148561089TC0.00975NBPF15+FALSE
chr5109204057TA0.00614MAN2A1+FALSE
chr1913884096AG0.00049MRI1+TRUEAluSzSINE,Alu

Differential Expression Gene Analysis