Dataset Overview
RBPUBE2L3
Knock-MethodshRNA
RBP FamilyNon-canonical_RBP
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR424JSU
PlatformHiSeq
Pubmed ID32252787

UBE2L3 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of UBE2L3
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of UBE2L3


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1109737090GA0.00173KIAA1324+FALSE
chr582877162GA0.00296VCAN+FALSE(A)nSINE,Alu
chr128607959CA0.00230SESN2+FALSE
chr1942375611AG0.00426.FALSEAluSxSINE,Alu
chr110521200TC0.00013DFFA-TRUEAluYSINE,Alu
chr3196044972CT0.00258TCTEX1D2,TM4SF19-TCTEX1D2-FALSE
chr1158631171AC0.00815SPTA1-FALSE
chr1183094547TC0.00277LAMC1+FALSE
chr1183486859GA0.00831SMG7+FALSE
chr133149508AG0.00107SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr47060935GC0.00543GRPEL1-FALSETigger4aSINE,Alu
chr111083183GT0.00342TARDBP+FALSE
chr19161179TC0.00570.FALSEAluSxSINE,Alu
chr299812876AG0.00394MRPL30+TRUEAluJbSINE,Alu
chr11595006TC1.43617E-06CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr18938808CA0.00030ENO1-FALSE
chr1150048520CT0.00089VPS45+FALSE
chr534906692TC0.00021RAD1-TRUEAluJoSINE,Alu
chr184373309TC0.00627TTLL7-FALSE
chr146076468AG0.00069NASP+TRUEAluSxSINE,Alu
chr1160990875TC9.42851E-06F11R-FALSE
chr2242164677AG0.00117ANO7+TRUEAluSgSINE,Alu
chr155207985GA0.00156MROH7-TTC4,TTC4+FALSE
chr3160154971TC0.00820TRIM59-FALSEAluJbSINE,Alu
chr1144931392GA0.00241NBPF20,PDE4DIP+,-FALSE
chr565452100GT0.00600SREK1+FALSE(TTTTTG)nSINE,Alu
chr140147856TC0.00205HPCAL4-TRUE
chr1179044181AG0.00790FAM20B+TRUEAluSxSINE,Alu
chr1690037828GA0.00029CENPBD1-FALSETigger12SINE,Alu
chr541917697AT0.00051C5orf51+FALSE
chr1631469051TC0.00278.FALSEAluSzSINE,Alu
chr142884086GT0.00040RIMKLA+FALSE
chr19161203TC0.00235.FALSEAluSxSINE,Alu
chr674134744TC0.00214.FALSEAluSzSINE,Alu
chr6133135886AG0.00629RPS12+FALSE
chr237327666TC0.00028.FALSE
chr5122359498AC0.00362PPIC-FALSE(AC)nSINE,Alu
chr632796463AC0.00680.FALSE(CCCCA)nSINE,Alu
chr11152310CT0.00133SDF4-FALSE
chr2112252630AC0.00040MIR4435-2HG-FALSE
chr128823671TC0.00073PHACTR4+FALSE
chr16583383TC0.00305NOL9-TRUEAluSqSINE,Alu
chr110519910TC0.00735.FALSEAluJrSINE,Alu
chr120976589CT0.00407PINK1,PINK1-AS+,-FALSE
chr131838550TA0.00595FABP3-FALSE
chr274442548CT0.00035.FALSE
chr1163309219AT0.00023NUF2+FALSE
chr4144442611TC0.00899SMARCA5+FALSE
chr4153898334AG0.00662FHDC1+FALSEAluJoSINE,Alu
chr1531619607GA0.00887KLF13+FALSE
chr110519932TC0.00012.FALSEAluJrSINE,Alu
chr237330431TC0.00231.FALSEAluSq2SINE,Alu
chr42940243TA0.00028NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr1089004545TC0.00192NUTM2A-AS1-FALSEMSTASINE,Alu
chr1045499895GA0.00255ZNF22+FALSE
chr11594835CG0.00195CDK11B,SLC35E2B-FALSE
chr116889624TC0.00795NBPF1-TRUE
chr119984098CG0.00826MINOS1-NBL1,NBL1+FALSE
chr2128952015AG0.00908UGGT1+TRUEAluSx1SINE,Alu
chr2118589029TG0.00058DDX18+FALSE
chr2127826533AG0.00104BIN1-FALSE
chr127202812TC0.00353.FALSEAluSq2SINE,Alu
chr1674655596TG0.00028RFWD3-FALSEAluSxSINE,Alu
chr1461112736TG0.00418SIX1-FALSE(T)nSINE,Alu
chr1145512073AG0.00285NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr12335348CT0.00018RER1+FALSE
chr262095566CT0.00471CCT4-FALSE
chr9136897584CA0.00060BRD3-FALSEA-richSINE,Alu
chr269690885TC0.00970AAK1-TRUEAluSx3SINE,Alu
chr1990984GA0.00787AGRN+FALSE
chr86263057AC0.00419LOC100287015-FALSE
chr386993604GT0.00195VGLL3-FALSEAluJoSINE,Alu
chr16283305TC0.00129ICMT-TRUEAluSx3SINE,Alu
chr154231847AC0.00097NDC1-FALSE
chr153288870AG3.51337E-08ZYG11B+TRUEAluJoSINE,Alu
chr3196078364GA6.64958E-05.FALSEGA-richSINE,Alu
chr3155660279AG0.00594.FALSE
chr644417159AG0.00959CDC5L+TRUEFLAM_CSINE,Alu
chr267631831GA0.00423ETAA1+FALSE
chr633268621TC0.00367.FALSEAluYSINE,Alu
chr638670804GC0.00400GLO1-FALSE
chr1453243434TC5.94655E-10GNPNAT1-TRUEAluSx3SINE,Alu
chr1184761365AG0.00758FAM129A-FALSEAluJoSINE,Alu
chr11650657CG0.00379CDK11B,CDK11A-FALSE
chr146829013AG0.00360NSUN4+FALSE
chr128836872AG0.00019SNHG3,RCC1+TRUEAluScSINE,Alu
chr138326774TC0.00664INPP5B-TRUEAluJrSINE,Alu
chr1153599390TC0.00135S100A13-FALSE
chr2201774342TC0.00127.FALSEAluSzSINE,Alu
chr1015119789TC0.00366ACBD7-TRUEAluSx1SINE,Alu
chr1911256725TC7.46879E-09SPC24-TRUEAluJr4SINE,Alu
chr1115248084CT0.00171NRAS-FALSE
chr439550085TC3.55103E-05UGDH-AS1,SMIM14+,-FALSEFLAM_CSINE,Alu
chr187379494AT0.00364SEP15-FALSE
chr254896390GT0.00110SPTBN1+FALSE
chr133148623AG0.00221SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr1150619971GA0.00126GOLPH3L-FALSEAluJoSINE,Alu
chr9132573290CT0.00881TOR1B+FALSE
chr8145159709CA0.00314MAF1+FALSE
chr133149408AG0.00624SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1202993614GT0.00990TMEM183A+FALSE(T)nSINE,Alu
chr1079800439AT0.00380RPS24+FALSE
chr2216148322AG0.00933.FALSEL1ME2zSINE,Alu
chr2202032107AG0.00401CFLAR+TRUEAluJoSINE,Alu
chr136806071GA0.00126STK40-FALSE
chr136068276TC0.00225PSMB2-TRUEAluScSINE,Alu
chr5175803244AG0.00245.FALSEAluSc8SINE,Alu
chr657034840TG0.00581ZNF451,LOC101927211+,-FALSE
chr2232328545CT0.00581NCL-FALSE
chr119934893CA0.00171MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr182544702GA0.00522METTL4-FALSE
chr299812978AG0.00167MRPL30+TRUEAluJbSINE,Alu
chr830536015TC6.64592E-05GSR-TRUEAluJrSINE,Alu
chr299812447AG0.00587MRPL30+TRUEAluSxSINE,Alu
chr1956090351CT1.52943E-09ZNF579-FALSE
chr1100548868TC0.00114MFSD14A+FALSE
chr399517483CT0.00070MIR548G-FALSE(TG)nSINE,Alu
chr146075663AG0.00013NASP+TRUEAluSx4SINE,Alu
chr101086801GC0.00421IDI2-AS1,IDI1+,-FALSE
chr9114696428GT0.00163UGCG+FALSE(TGTTTTT)nSINE,Alu
chr285773494TC0.00099GGCX-TRUEAluYSINE,Alu
chr246524711CT0.00513EPAS1+FALSE
chr131351513GA0.00265SDC3-FALSE
chr314986461TC3.09385E-06FGD5-AS1-TRUEAluSq2SINE,Alu
chr174665493GA0.00128FPGT-TNNI3K,FPGT+FALSE
chr146828657CT0.00378NSUN4+FALSE
chr1227922767GT0.00202SNAP47,JMJD4+,-FALSE
chr1490509564CT0.00552TDP1+FALSE
chr231491075AG0.00061EHD3+FALSE
chr1776626300CT0.00097LOC101928710-FALSE
chr176255228GA0.00073RABGGTB,SNORD45B+FALSE
chr238971635CG0.00011SRSF7-FALSE
chr1047221465TC0.00201.FALSEAluJbSINE,Alu
chr1168218522AG0.00073.FALSEAluSzSINE,Alu
chr1205737665GT0.00025RAB29-FALSEAluSq2SINE,Alu
chrX77083939TC5.71267E-05MAGT1-TRUEAluSzSINE,Alu
chr1161930908GA0.00664ATF6+FALSE
chr42940098TC0.00034NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr131344952CT0.00842SDC3-FALSE
chr452888499GA0.00366SGCB-FALSE
chr1179876988CG0.00047TOR1AIP1+FALSE
chr171684352TC0.00793SMYD4-TRUEAluSx1SINE,Alu
chr671299074AG0.00824.FALSEAluSx1SINE,Alu
chr1761909370GA0.00152PSMC5+FALSE
chr448854139TC0.00133OCIAD1+FALSEL2cSINE,Alu
chr1179042550AG0.00831FAM20B+TRUEAluSx1SINE,Alu
chr13730400TC0.00018CEP104-TRUEAluSx3SINE,Alu
chr11252221TC0.00728CPSF3L-TRUEAluSxSINE,Alu
chr11164179GA0.00983SDF4-FALSEG-richSINE,Alu
chr116945570AG0.00131CROCCP2-FALSE
chr6158517308AG0.00959SYNJ2+FALSE
chr110518821TC0.00277.FALSEAluSx1SINE,Alu
chr1145513017AG0.00142NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr11677253TC0.00145SLC35E2-FALSE
chr1144931727GA0.00211NBPF20,PDE4DIP+,-FALSE
chr1149913733TC0.00143OTUD7B-TRUEMER96BSINE,Alu
chr1156563898TC0.00216NAXE+FALSE
chr488059194CT0.00681AFF1+FALSE
chr145976220AG0.00031MMACHC+TRUE
chr133149338AG0.00367SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr132742441GA2.50972E-10LCK+FALSE
chr1120695749AG0.00130.FALSE
chr2128620438CA0.00230AMMECR1L-FALSE
chr4165998078TC0.00567TMEM192-TRUEAluSxSINE,Alu
chr193299394AG0.00655FAM69A,RPL5+,-FALSE
chr1669151495TA0.00304HAS3+FALSE(T)nSINE,Alu
chr642856156AG0.00105RPL7L1+TRUEAluSzSINE,Alu
chr110518734TC0.00249.FALSEAluSx1SINE,Alu
chr2127826533AG0.00942BIN1-FALSE
chr239010088AG0.00192.FALSEAluSpSINE,Alu
chr2132481508CG0.00093C2orf27A+FALSE
chr136068370TC0.00067PSMB2-TRUEAluScSINE,Alu
chr1098278593AT0.00792TM9SF3-FALSE
chr1205759960CT4.24096E-05SLC41A1-FALSE
chr679595097AG0.00712IRAK1BP1+FALSE
chr1109475706TC0.00375GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr7143003525TA0.00064CASP2+FALSEAluYSINE,Alu
chr7143003523TG2.48474E-05CASP2+FALSEAluYSINE,Alu
chr1178887208AT0.00239RALGPS2+FALSE
chr1114306563TA0.00191RSBN1-FALSE
chr8128944720GT0.00751PVT1+FALSE
chr1565442678TC2.30704E-07CLPX-TRUEAluSg4SINE,Alu
chr1566678CT0.00559.FALSE
chr3172117458AC0.00011FNDC3B+FALSE
chr120826781CT1.74444E-05MUL1-FALSE
chr352289709GC4.88711E-11WDR82-FALSEMIRSINE,Alu
chr1657505635GT0.00974POLR2C+FALSE
chr132373437GA1.22125E-14PTP4A2-FALSE
chr765844563GA0.00581LINC00174-FALSE
chr167874697TC0.00642SERBP1-TRUEAluSx3SINE,Alu
chr1590815820AG0.00171.FALSEFRAMSINE,Alu
chr3129152089GA0.00154MBD4-FALSE
chr110517290TC0.00437.FALSEAluJrSINE,Alu
chr720178562TC1.84789E-06MACC1,LOC101927668-TRUEAluYSINE,Alu
chr2217366195CA0.00929.FALSE
chr34403394AG0.00388SUMF1-FALSE
chr11337841CA0.00186MRPL20-FALSE
chr1728513176GA0.00996NSRP1+FALSEAluJrSINE,Alu
chr178483452CT0.00045DNAJB4+FALSEL1MB7SINE,Alu
chr3121154974TC0.00183POLQ-FALSE
chr4177252238AG0.00061SPCS3+TRUE
chr121102501GA0.00148HP1BP3-FALSE
chr1114227223GA0.00699MAGI3+FALSE
chr11595604AT0.00233CDK11B,SLC35E2B-FALSEAluJrSINE,Alu
chr162882267GC0.00252ZG16B+FALSE
chr110520178TC2.78615E-06.FALSEAluSxSINE,Alu
chr189887603CT0.00308GBP1P1+FALSE
chr133149486AG0.00528SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1924103987AG1.84513E-07ZNF726+TRUEAluSg4SINE,Alu
chr111119950GA4.66412E-05SRM-FALSE
chr16282420TC0.00779ICMT-TRUEAluSzSINE,Alu
chr671298639AG0.00339.FALSEAluSpSINE,Alu
chr116891365GA1.42078E-05NBPF1-FALSE
chr3172351006CG6.14326E-06NCEH1-FALSE
chr1610624953TC0.00056EMP2-TRUEAluSx3SINE,Alu
chr119543352TC0.00715LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr3195435168TG0.00111LINC00969+FALSE
chr21637201CT5.10703E-15PXDN-FALSE
chr2206983255TC0.00246.FALSEAluJbSINE,Alu
chr165693725CT0.00202AK4+FALSE
chr175288082AG0.00184RABEP1+TRUE
chr2128060859TA0.00016MAP3K2-FALSE
chr310192608AG0.00030VHL+TRUEAluSx1SINE,Alu
chr1117945042GA0.00150MAN1A2+FALSE
chr2183622547TG0.00346DNAJC10+FALSE
chr989627066AG0.00588LOC440173-FALSE
chr1762541203GA0.00660SMURF2-FALSE
chr1204521631AG0.00024MDM4+TRUEAluSgSINE,Alu
chr1120458004AT0.00247NOTCH2-FALSE
chr10100177984CT6.55965E-05HPS1-FALSE
chr110520984GT0.00305DFFA-FALSEAluYSINE,Alu
chr11419690AG0.00464ATAD3B+TRUEAluYk2SINE,Alu
chr175288079AC0.00085RABEP1+FALSE
chr5118174757TC0.00032DTWD2-TRUEAluYSINE,Alu
chr1144917546AG0.00614NBPF20,PDE4DIP+,-FALSE
chr174928416AG0.00941KIF1C+TRUEAluSzSINE,Alu
chr1145512123AG3.10159E-05NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr2174090320TA0.00174ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr194335333GT0.00510DNTTIP2-FALSE
chr116918717CT0.00550NBPF1-FALSE

Differential Expression Gene Analysis