Dataset Overview
RBPDDX6
Knock-MethodshRNA
RBP FamilyDEAD
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR119QWQ
PlatformHiSeq
Pubmed ID32252787

DDX6 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of DDX6
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of DDX6


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1138156GT0.00177LOC729737-FALSE
chr254120820GA0.00262PSME4-FALSE
chr1226172221TC0.00118SDE2-FALSEL1MEfSINE,Alu
chr2128605225GA0.00401POLR2D-FALSE
chr1148252049AC0.00666NBPF8,NBPF14,NBPF9-FALSE
chr151873951GA0.00591EPS15-FALSE
chr111982544TC4.37710E-05KIAA2013-FALSE
chr152817376TC0.00175CC2D1B-TRUEAluSg4SINE,Alu
chr128661653AG9.75782E-05MED18+TRUEAluSgSINE,Alu
chr56748659TC0.00032PAPD7+FALSE
chr237327676TC0.00462.FALSE
chr811700373TC0.00212CTSB-TRUEAluSq2SINE,Alu
chr5134061334AG0.00721SEC24A+FALSE
chr12120898553AG0.00233GATC+TRUEAluYSINE,Alu
chr10119766673TG0.00082RAB11FIP2-FALSE
chr632800221CT0.00900.FALSE(GCATCA)nSINE,Alu
chr47764148GA2.22190E-11AFAP1,AFAP1-AS1+,-FALSE
chr13697486CG0.00110LRRC47-FALSEAluScSINE,Alu
chr12123346997GC0.00275HIP1R+FALSE
chr7158590740AT0.00211ESYT2-FALSE
chr1109818162TC0.00316CELSR2+FALSE
chr7156763172AG0.00874NOM1+TRUEAluSxSINE,Alu
chr237327662TC0.00058.FALSE
chr1911256689TC9.47404E-06SPC24-TRUEAluJr4SINE,Alu
chr1220231959TC0.00028RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr1144851999AC0.00385NBPF20,PDE4DIP+,-FALSE
chr439551167TC0.00361UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr1201975173GT0.00356RNPEP+FALSE
chr119543353TC0.00091LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr136068370TC0.00789PSMB2-TRUEAluScSINE,Alu
chr624720531CG0.00960.FALSE(GGC)nSINE,Alu
chr123833608GA0.00890E2F2-FALSE
chr2146353985AG0.00985LINC01547-FALSEMER5ASINE,Alu
chr4110635486AG0.00021PLA2G12A-FALSE
chr116893686GC0.00171NBPF1-FALSE
chr1148556726GT0.00758.FALSE
chr1160966434TC0.00175F11R-TRUEAluSgSINE,Alu
chr211323108TA0.00100ROCK2-FALSE(TA)nSINE,Alu
chr568505909AG0.00178CENPH+TRUEAluSx3SINE,Alu
chr16282237TC0.00771ICMT-TRUEAluSzSINE,Alu
chr133960062AG0.00437ZSCAN20+FALSE
chr613789450TC0.00235MCUR1-TRUEAluSgSINE,Alu
chr2025428587AG0.00137GINS1+TRUEAluJbSINE,Alu
chr110517276TC0.00039.FALSEAluJrSINE,Alu
chr1541591039AG0.00214OIP5-AS1+TRUEAluSx1SINE,Alu
chr1113672616AG0.00553.FALSEAluJbSINE,Alu
chr128261661GA0.00872SMPDL3B+FALSE
chr131192650TG0.00727MATN1,MATN1-AS1+,-FALSE
chr11421531CA0.00467ATAD3B+FALSE
chr2176042871AT0.00204ATP5G3-FALSE
chr315838717AC0.00673ANKRD28-FALSE(A)nSINE,Alu
chr5140594466GA0.00209PCDHB13+FALSE
chr1669151495TA0.00304HAS3+FALSE(T)nSINE,Alu
chr237331107TC0.00020.FALSEAluSx1SINE,Alu
chr1120539691GT0.00350NOTCH2-FALSE
chr159121768GC0.00196MYSM1-FALSE
chr1765334846TC0.00456PSMD12-FALSEAluSqSINE,Alu
chr1109737090GA0.00173KIAA1324+FALSE
chr145279903CT0.00052.FALSE(TCTT)nSINE,Alu
chr16694226CT0.00742THAP3+FALSE
chr1681064492AG0.00935CENPN+TRUEAluSgSINE,Alu
chr642856176AG0.00202RPL7L1+TRUEAluSzSINE,Alu
chr125570563AT0.00276RSRP1-FALSEAluSINE,Alu
chr2204162597AG0.00296CYP20A1+TRUEAluSxSINE,Alu
chr273460299GC0.00180PRADC1-FALSE(CGGCGC)nSINE,Alu
chr261150192CA0.00436REL+FALSEAluSz6SINE,Alu
chr2172178540TC0.00040METTL8-TRUEAluSx3SINE,Alu
chrX118672577TC0.00080CXorf56-TRUEAluSxSINE,Alu
chr3169808354GA0.00015PHC3-FALSE
chr128567501AG0.00887.FALSE
chr4119952955CT0.00278SYNPO2+FALSE
chr136068275TC0.00098PSMB2-TRUEAluScSINE,Alu
chr2234749258TC0.00710HJURP-FALSE
chr457326329AG0.00077PAICS+TRUEAluJrSINE,Alu
chr239009427AG0.00673.FALSEAluSx3SINE,Alu
chr388104073GC0.00887CGGBP1-FALSE
chr194702991GC0.00397ARHGAP29-FALSE
chr119543247TC4.83051E-05LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1545775144TC0.00867SLC30A4-TRUEAluJrSINE,Alu
chr128564612CA0.00714ATPIF1+FALSE
chr2204301752GC0.00029RAPH1-FALSE
chr473957426GT0.00434ANKRD17-FALSE
chrX150573750AT0.00887VMA21+FALSE
chrX123046757AG0.00535XIAP+TRUEAluSzSINE,Alu
chr312942851CG0.00013IQSEC1-FALSE
chr1610623631TC1.36144E-05EMP2-TRUEAluSpSINE,Alu
chr1321547676TC0.00403LATS2-FALSE
chr1145512141AG0.00215NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1326539AG0.00719.FALSE
chr1244572643CA0.00560ADSS-FALSE
chr239010088AG0.00192.FALSEAluSpSINE,Alu
chr239009355AG0.00079.FALSEAluSx3SINE,Alu
chr310322331CG0.00180TATDN2+FALSE
chr178414285TA0.00256FUBP1-FALSE
chr6107113955AG0.00265QRSL1+TRUEAluSgSINE,Alu
chr11668089GT0.00801SLC35E2-FALSEAluSzSINE,Alu
chr1549283066TG0.00065SECISBP2L-FALSE
chr115904318CT9.04121E-06AGMAT-FALSE
chr128150601AT0.00558STX12+FALSE
chr5170837892CA0.00725.FALSE
chr237327665TC2.45403E-06.FALSE
chr1913884096AG0.00049MRI1+TRUEAluSzSINE,Alu
chr5177576458AT0.00427.FALSE
chr1145511962AG0.00091NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr4128757415AG0.00367.FALSEAluYSINE,Alu
chr119565338CT0.00631LOC101927895,EMC1+,-FALSE
chr13730400TC0.00894CEP104-TRUEAluSx3SINE,Alu
chr5125962528AG0.00924PHAX+TRUEAluSzSINE,Alu
chr19161199TC0.00468.FALSEAluSxSINE,Alu
chr1143399383TA0.00198.FALSEL1MC4SINE,Alu
chr1015120275TC0.00387ACBD7-TRUEL1PA7SINE,Alu
chr3172224303AG0.00524TNFSF10-FALSE
chr237330587TC0.00112.FALSEAluSq2SINE,Alu
chr19329105TA0.00233H6PD+FALSE
chr2187544223TG0.00254ITGAV+FALSE
chr136770601GT0.00055THRAP3+FALSE(T)nSINE,Alu
chr2238005476CT0.00456COPS8+FALSE
chr237327651TC0.00395.FALSE
chr129464349AC0.00042LOC642846+FALSE
chr1184762524TC0.00778FAM129A-TRUEAluSzSINE,Alu
chr1541591457AG1.25234E-05OIP5-AS1+TRUEAluSxSINE,Alu
chr7144060286AG0.00674ARHGEF5+FALSE
chr5180682610TC0.00014CTC-338M12.4+FALSE
chr3155660279AG0.00594.FALSE
chr1220231997TC0.00244RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr116889866GA0.00995NBPF1-FALSE
chr182763697CT8.35636E-08SMCHD1+FALSE
chr12123253741AG0.00134DENR+TRUE(AT)nSINE,Alu
chr152375677TC0.00542RAB3B-FALSEMIRbSINE,Alu
chr1226333558AC0.00722ACBD3-FALSE(CAAAA)nSINE,Alu
chr1109855150AC0.00062SORT1-FALSEA-richSINE,Alu
chr1932005AG0.00110.FALSE
chr1292537702TA0.00368BTG1-FALSE
chr258387000CT0.00027VRK2,FANCL+,-FALSE
chr1148561089TC0.00975NBPF15+FALSE
chr2202152108AG0.00018CASP8+FALSEAluJbSINE,Alu
chr9125609941GA0.00043.FALSE
chr125894469AT0.00326LDLRAP1+FALSEMIRbSINE,Alu
chr631379931GA0.00093.FALSE
chr1114940216TG0.00674TRIM33-FALSE(T)nSINE,Alu
chr162627128AG0.00111PATJ+TRUEAluSxSINE,Alu
chr116890320TC0.00045NBPF1-FALSE
chr16282334TC0.00408ICMT-TRUEAluSzSINE,Alu
chr146033514GA0.00073AKR1A1+FALSEAluYk3SINE,Alu
chr152306087CT0.00022NRDC-FALSE(TCA)nSINE,Alu
chr1156613517CA0.00011BCAN+FALSE
chr312624763TC1.62214E-06MKRN2+FALSE
chr517276848CA0.00634BASP1+FALSE(A)nSINE,Alu
chr127182751CA0.00122.FALSE
chr5130494984AT0.00018HINT1-FALSE
chr2191745647CT2.95764E-05GLS+FALSE
chr1114306369AT0.00834RSBN1-FALSE
chr11252749TC0.00875CPSF3L-TRUEAluSpSINE,Alu
chr1180247477CT0.00060.FALSE
chr117345250AT0.00183SDHB-FALSE
chr5110463616GT0.00264WDR36+FALSE(T)nSINE,Alu
chr1222906426TC0.00322BROX+FALSEAluSxSINE,Alu
chr153359745AG0.00129ZYG11A+TRUEAluSx4SINE,Alu
chr1231398555AG0.00401GNPAT+FALSE
chr116945780CT0.00034CROCCP2-FALSE
chr2132481529CT0.00028C2orf27A+FALSE
chr159249682GA0.00074JUN-FALSE
chr1145283718GA0.00989NBPF20,NOTCH2NL+FALSE
chr1145281656AT0.00839NBPF20,NOTCH2NL+FALSE
chr11118915753TC8.93388E-07HYOU1-FALSE
chr3148748199CA3.38210E-05HLTF-FALSE
chr131905886CA0.00273SERINC2+FALSE
chr2035520976TC0.00254TLDC2,SAMHD1+,-FALSEFLAM_ASINE,Alu
chr174672474GA0.00014FPGT-TNNI3K,FPGT+FALSEX12_DNASINE,Alu
chr111084103TA0.00968TARDBP+FALSE
chr3194369580CA0.00042LSG1-FALSE
chr110520180TC0.00959.FALSEAluSxSINE,Alu
chr16583066TC0.00209NOL9-TRUEAluSx4SINE,Alu
chr310192816AG0.00010VHL+TRUEAluSx1SINE,Alu
chr2100019496AG0.00789REV1-FALSE
chr7100031497TG0.00119MEPCE+FALSE
chr76066461TC2.08606E-05EIF2AK1-FALSE
chr564964623TC1.14652E-05SGTB-TRUEAluSx1SINE,Alu
chr234080819AC0.00815LINC01317+FALSEMSTDSINE,Alu
chr1153917621GC0.00020DENND4B-FALSE
chr2128602455TC0.00632.FALSEAluSq2SINE,Alu
chr237328100TC0.00027.FALSE
chr11549354GA0.00383.FALSEHAL1SINE,Alu
chr1145511796TG0.00428NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSE(T)nSINE,Alu
chr1179829093TC0.00056TOR1AIP2-TRUEAluJrSINE,Alu
chr159122059GA0.00476MYSM1-FALSE
chr337368755TA9.43816E-08GOLGA4+FALSE
chr110520487TC0.00257.FALSEAluSx1SINE,Alu
chr1144917546AG0.00614NBPF20,PDE4DIP+,-FALSE
chr1753470462CT0.00230MMD-FALSE
chr1117531179GA0.00116PTGFRN+FALSE
chr285772406GA0.00278GGCX-FALSE
chr439550085TC3.55103E-05UGDH-AS1,SMIM14+,-FALSEFLAM_CSINE,Alu
chr224223142AG0.00524UBXN2A+TRUEAluScSINE,Alu
chr192976590GA0.00768EVI5-FALSE
chr1145689611CA0.00142NBPF20,NBPF10+FALSEAluSgSINE,Alu
chr124301900GA2.65815E-05.FALSE
chr116889563CA0.00037NBPF1-FALSE
chr13697550CA0.00078LRRC47-FALSEAluScSINE,Alu
chr1146649884TA0.00338PDIA3P1+FALSE
chr343098969TG0.00596FAM198A+FALSEL1ME3GSINE,Alu
chr1593568295GA0.00225CHD2+FALSE
chr131905886CA0.00226SERINC2+FALSE
chr146076642AG0.00552NASP+TRUEAluSxSINE,Alu
chr1100654773TC0.00810DBT-TRUEAluSzSINE,Alu
chr6143382538AT0.00145AIG1+FALSE
chr642855979AG8.12389E-06RPL7L1+TRUEAluSzSINE,Alu
chr765844563GA0.00581LINC00174-FALSE
chr238298419AG0.00575CYP1B1-FALSE
chr119543349TC0.00060LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr2112252626AC0.00048MIR4435-2HG-FALSE
chr333185037AC0.00144CRTAP+FALSEL2aSINE,Alu
chr228002603CA0.00010MRPL33+FALSE
chr1585184816TC3.05793E-06WDR73,SCAND2P+,-FALSEAluSzSINE,Alu
chr47764501TA5.61153E-09AFAP1,AFAP1-AS1+,-FALSE
chr1540712737TC0.00525IVD+FALSE
chr4183721749GA0.00324TENM3+FALSE
chr286252038TC0.00931POLR1A-TRUEAluSq2SINE,Alu
chr1161930908GA0.00664ATF6+FALSE
chr5125961661AG4.29043E-06PHAX+TRUEAluSz6SINE,Alu
chr211323078CT0.00539ROCK2-FALSE
chr3150261569TG0.00173SERP1-FALSE
chr127107948GA0.00177ARID1A+FALSE
chr227293351CT0.00314AGBL5,OST4+,-FALSE
chr1184663581TC0.00265EDEM3-FALSE
chr1911256626TC1.61091E-07SPC24-TRUEAluJr4SINE,Alu
chr1675480021TC0.00270TMEM170A-TRUEAluSg4SINE,Alu
chr2054943385CA0.00844FAM210B+FALSE
chr358141791AG0.00696FLNB+FALSE
chr1590375419TC0.00521C15orf38-AP3S2,AP3S2-TRUEAluJrSINE,Alu
chr127874481CA0.00046AHDC1-FALSE
chr1114226255GA0.00381MAGI3+FALSE
chr310192596AG9.40892E-06VHL+TRUEAluSx1SINE,Alu
chrX3523048AT0.00055PRKX-FALSE
chr197144750TC0.00262.FALSE
chr116902943TC0.00833NBPF1-FALSE
chr2134729931AG0.00040IFNAR1+TRUEAluSg7SINE,Alu
chr1145511796TG0.00173NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSE(T)nSINE,Alu
chr12323041TC0.00970MORN1-FALSE
chr2209180073CA0.00478PIKFYVE+FALSE
chr110517513TC0.00088.FALSEAluSx1SINE,Alu
chr119953120GA0.00212MINOS1,MINOS1-NBL1+FALSE
chr111187199GT0.00047MTOR-FALSE
chr345721922AG0.00181LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr19163334TC0.00889.FALSEAluSpSINE,Alu
chr162380298GA0.00025PATJ+FALSE
chr1670695982TC0.00926MTSS1L-FALSE
chr477082799GC0.00148SCARB2-FALSE
chr1146740502CG0.00692CHD1L+FALSE
chr238971644TG0.00239SRSF7-FALSE
chr111783902AG0.00336.FALSEAluSqSINE,Alu
chr190049040AG0.00190LRRC8B+FALSE
chr127205214TC0.00048.FALSEAluScSINE,Alu
chr273460314CT0.00333PRADC1-FALSE(CGGCGC)nSINE,Alu
chr2172412008CG0.00982CYBRD1+FALSE
chr146751578TG0.00380LRRC41-FALSE
chr642856978AG0.00819RPL7L1+TRUEAluSpSINE,Alu
chr1113212976CT0.00043CAPZA1+FALSE
chr6109785887TC7.14632E-06MICAL1,ZBTB24-TRUEAluJrSINE,Alu
chr1148343689AG0.00517NBPF8,NBPF14,NBPF9-FALSE
chr3141164940CA0.00194ZBTB38+FALSE
chr3155660833AG0.00020.FALSEAluSzSINE,Alu
chr146774783AG1.06423E-10UQCRH+FALSE(AGG)nSINE,Alu
chr1109181317CG0.00597FAM102B+FALSE
chr314986098TC0.00000FGD5-AS1-TRUEFLAM_CSINE,Alu
chr642856118AG0.00743RPL7L1+TRUEAluSzSINE,Alu
chr3160213317TA0.00208KPNA4-FALSE
chr1180144485GA0.00665QSOX1+FALSE
chr187379498TG0.00784SEP15-FALSE
chr535878249GA0.00421IL7R+FALSE
chr167874696TC0.00839SERBP1-TRUEAluSx3SINE,Alu
chr16582221TC6.47537E-05NOL9-TRUEAluSq4SINE,Alu
chr1453242674TC1.74446E-05GNPNAT1-TRUEAluJrSINE,Alu
chr439460539GA0.00323RPL9-FALSE
chr19163402TC4.95479E-05.FALSEAluSpSINE,Alu
chr1533064461CT0.00653FMN1-FALSE
chr1150939883AG0.00472CERS2-FALSE
chr5179157298TG0.00816CANX+FALSE
chr1148928344AG0.00608LOC645166+FALSETAR1SINE,Alu

Differential Expression Gene Analysis