Dataset Overview
RBPSSB
Knock-MethodshRNA
RBP FamilyRRM_3
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR891AXF
PlatformHiSeq
Pubmed ID32252787

SSB - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of SSB
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of SSB


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr285548854TC0.00097TGOLN2-FALSE
chr1186390303AC0.00455C1orf27+FALSEL1ME3FSINE,Alu
chr5159520661TC0.00776PWWP2A-FALSE
chr1117945042GA0.00150MAN1A2+FALSE
chr1619715543TC0.00879.FALSEAluSgSINE,Alu
chr297884961GA0.00668ANKRD36+FALSE
chr153708530TC9.40494E-05LRP8-FALSE(TA)nSINE,Alu
chr1298943202AG6.48893E-05TMPO+TRUEAluSzSINE,Alu
chr237328016TC5.08368E-07.FALSE
chr116953672CT0.00243CROCCP2-FALSE
chr1225706943CT0.00229ENAH-FALSE
chr1120163247TC0.00010ZNF697-FALSE
chr2101186088CT0.00817PDCL3+FALSE
chr2128602967TG0.00026.FALSEAluSpSINE,Alu
chrX16781156AG0.00061.FALSEAluJoSINE,Alu
chr42940265TC0.00413NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr574072634TA0.00187NSA2+FALSE
chr1165370475GC0.00256RXRG-FALSE
chr72650926GA0.00306IQCE+FALSE
chr11118661811TG0.00582DDX6-FALSE
chr1109535117CT0.00211WDR47-FALSE
chr1145100851AG0.00066NBPF20,SEC22B+FALSEAluSg4SINE,Alu
chr439550739TC0.00231UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr16283305TC0.00129ICMT-TRUEAluSx3SINE,Alu
chr167874696TC0.00012SERBP1-TRUEAluSx3SINE,Alu
chr1156613401TC5.47226E-05BCAN+FALSE
chr1225683180GT0.00076ENAH-FALSE
chr1118408218CA0.00857GDAP2-FALSE
chr9125609941GA0.00043.FALSE
chr1252710721GC0.00519KRT83-FALSE
chr146751319GA0.00085LRRC41-FALSE
chr194351065AT0.00142GCLM-FALSE
chr2152132130AG6.12116E-05NMI-FALSE
chr145279903CT0.00052.FALSE(TCTT)nSINE,Alu
chr537290323TC0.00029.FALSEAluSzSINE,Alu
chr16283306TC0.00558ICMT-TRUEAluSx3SINE,Alu
chr1184762524TC0.00260FAM129A-TRUEAluSzSINE,Alu
chr3196079390TC2.00948E-06.FALSEAluSxSINE,Alu
chr81730500AG3.50527E-05CLN8+TRUEAluSx1SINE,Alu
chr457326873AG0.00034PAICS+TRUEAluSx1SINE,Alu
chr1463841400AC0.00122PPP2R5E-FALSE
chr9130209956AT0.00221RPL12-FALSE
chr1214638296GA3.68085E-08PTPN14-FALSE
chr131532379AG0.00061PUM1-FALSE
chr132953214AG0.00837ZBTB8B+TRUEAluSzSINE,Alu
chr12124146100AG4.66106E-08GTF2H3+TRUEAluSx4SINE,Alu
chr417803604TC0.00414DCAF16-TRUEAluYSINE,Alu
chr1205272926CT0.00690NUAK2-FALSE
chr119670860AG0.00419CAPZB-FALSE
chr9137330709GT0.00965RXRA+FALSE(GCTG)nSINE,Alu
chr41305799CT0.00730MAEA+FALSE
chr9137330716AC0.00058RXRA+FALSE
chr1667715404TC0.00102GFOD2-TRUEAluSzSINE,Alu
chr373112378AG0.00261PPP4R2,EBLN2+FALSE
chr1236716959CT0.00727HEATR1-FALSE
chr12990912AC0.00244WNK1+FALSE
chr195658346TA0.00961TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr4248996AG0.00123ZNF876P+TRUEAluYk3SINE,Alu
chr1452906081TG0.00602TXNDC16-FALSE
chr274090062TG0.00248STAMBP+FALSE
chr1120539687TC0.00179NOTCH2-FALSE
chr1206635247CT0.00291SRGAP2+FALSE(AC)nSINE,Alu
chr2113289701TG0.00994TTL+FALSE
chr1158066834AG0.00609KIRREL+FALSE
chr142884086GT0.00040RIMKLA+FALSE
chr299812447AG0.00587MRPL30+TRUEAluSxSINE,Alu
chr416040617CT0.00032PROM1-FALSE
chr765844062TA0.00733LINC00174-FALSE
chr125893928TA0.00388LDLRAP1+FALSE
chr122854931CA0.00238ZBTB40+FALSEA-richSINE,Alu
chr298090925TC0.00056LOC100506076-FALSEL1PREC2SINE,Alu
chr5154194459CA0.00832LARP1+FALSE
chr352028445CT0.00934RPL29-FALSE
chr116957414CT0.00708.FALSE
chr144459935TC0.00953CCDC24+FALSEAluJbSINE,Alu
chr1611929653CT0.00333RSL1D1-FALSELTR14BSINE,Alu
chr178378932AG0.00372MYH10-FALSE
chr544826677GT0.00941.FALSE(T)nSINE,Alu
chr121544447GA0.00115ECE1-FALSE
chr3179117128TC0.00112GNB4-TRUEAluSzSINE,Alu
chr116944809GC9.47535E-05CROCCP2-FALSE
chr125688276AG0.00015TMEM50A+FALSE
chr1941220529CT0.00175COQ8B-FALSE
chr11549354GA0.00383.FALSEHAL1SINE,Alu
chr197543764CT0.00353DPYD-FALSE
chr1256510559AG0.00137RPL41+FALSE
chr13730332TC9.76659E-06CEP104-TRUEAluSx3SINE,Alu
chr116918717CT0.00550NBPF1-FALSE
chr128661653AG0.00483MED18+TRUEAluSgSINE,Alu
chr29558812GT0.00427ITGB1BP1-FALSE
chr531554465AT1.69098E-06C5orf22+FALSE
chr137945905AT0.00038ZC3H12A+FALSE
chr128835937AG0.00025SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr187200770CT0.00623SH3GLB1+FALSE
chr1230416399GT5.37638E-05GALNT2+FALSE
chr153359182AG0.00321ZYG11A+TRUEAluSxSINE,Alu
chr11126147697GA0.00237FOXRED1+FALSE
chr7116437206AG0.00118MET+FALSE
chr42940430TC2.47251E-05NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr116529004AC3.00007E-07ARHGEF19-FALSE
chr1540954864AG0.00636KNL1+TRUE
chr126449340GA0.00711PDIK1L+FALSE
chr189570148AG0.00084.FALSE
chr1148004440CA0.00082NBPF8-FALSE
chr2242164677AG0.00117ANO7+TRUEAluSgSINE,Alu
chr119543309TC0.00769LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1172547465AG0.00725SUCO+FALSE
chr199672346TC0.00222.FALSEAluJrSINE,Alu
chr2206986926TC0.00913.FALSEAluJrSINE,Alu
chr145975628AG0.00465MMACHC+TRUEAluSx4SINE,Alu
chr116927369CT0.00943NBPF1-FALSE
chr133148691AG2.12433E-06SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr9116022893CA0.00060SLC31A1+FALSE
chr3121507231AT0.00042IQCB1-FALSE
chr4165999189TC0.00614TMEM192-TRUEFLAM_CSINE,Alu
chr167874689TC0.00112SERBP1-TRUEAluSx3SINE,Alu
chr332567573GA0.00320DYNC1LI1-FALSE(AT)nSINE,Alu
chr135658260CG0.00477SFPQ-FALSE
chr1116237273AG0.00309VANGL1+FALSE
chr285773595TC0.00774GGCX-TRUEAluSx1SINE,Alu
chr16282215TC0.00187ICMT-TRUEAluSzSINE,Alu
chr1559428230GA0.00891MYO1E-FALSEMLT1BSINE,Alu
chr1569981CA4.36771E-05.FALSE
chr4187628395TA0.00000FAT1-FALSE
chr1145509570AG0.00037NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr1688789702GA0.00125PIEZO1-FALSE
chr3185646406AT0.00023TRA2B-FALSE
chr1109239334AT0.00035PRPF38B+FALSE
chr19162932AT0.00635.FALSE
chr237330517TC0.00324.FALSEAluSq2SINE,Alu
chr388191439AC0.00657CGGBP1,ZNF654+,-FALSE
chr342591446AG0.00012SEC22C-FALSE
chr1251325280AG0.00370METTL7A+TRUEAluSq2SINE,Alu
chr5174956493TA0.00466SFXN1+FALSE
chr11595538TC0.00718CDK11B,SLC35E2B-FALSEAluJrSINE,Alu
chr1182809019GA0.00274DHX9+FALSE
chr125894471GA0.00778LDLRAP1+FALSEMIRbSINE,Alu
chr299812311AG0.00016MRPL30+TRUEAluSxSINE,Alu
chr139988084GA0.00060BMP8A,PPIEL+,-FALSE
chr146075663AG0.00068NASP+TRUEAluSx4SINE,Alu
chr4152020781CT0.00925RPS3A+FALSE
chr138326700TC5.61462E-05INPP5B-TRUEAluJrSINE,Alu
chr1148932848AG0.00715LOC645166+FALSE
chr1541593269AG0.00196.FALSEAluSz6SINE,Alu
chr39517369CT0.00395SETD5+FALSE
chr1145511929AG0.00028NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1212277581CT4.20326E-05DTL+FALSE
chr1761502458TA0.00317TANC2+FALSE
chr177759578AG0.00492AK5+FALSE
chr189447720GA0.00521KYAT3,RBMXL1-FALSE
chr314986111TC0.00999FGD5-AS1-TRUEFLAM_CSINE,Alu
chr1179327011AG0.00930SOAT1+TRUE
chr1765335356TC5.15611E-11PSMD12-TRUEAluSxSINE,Alu
chr126608012CA0.00564SH3BGRL3+FALSE
chr2217129526AG0.00485TPTEP1+TRUEAluSzSINE,Alu
chr147844500TG0.00596CMPK1+FALSE
chr314986138TC1.80576E-11FGD5-AS1-TRUEFLAM_CSINE,Alu
chr3160969268CT0.00835NMD3+FALSE
chr126161104CA0.00030AUNIP-FALSEAluSc8SINE,Alu
chr825272446AT0.00405DOCK5+FALSE
chr42940164TC0.00381NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr1919791270AG0.00732ZNF101+TRUEAluSq2SINE,Alu
chr120238573TC0.00204OTUD3+FALSE
chr119542463TC0.00447LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1144932197TA0.00430NBPF20,PDE4DIP+,-FALSE
chr3172115474AG0.00012FNDC3B+FALSE(A)nSINE,Alu
chr110517550TC0.00457.FALSEAluSx1SINE,Alu
chr1179042482AG0.00079FAM20B+TRUEAluSx1SINE,Alu
chr1075009651TC0.00558DNAJC9-AS1,MRPS16+,-FALSEAluScSINE,Alu
chr1666923393AG0.00228PDP2+TRUEAluSzSINE,Alu
chr1963633CT0.00999WASH5P-FALSEMLT1KSINE,Alu
chr424578019GA0.00000DHX15-FALSE
chr128662212AG0.00098MED18+TRUEAluSq2SINE,Alu
chr129464350GC0.00209LOC642846+FALSE
chr1998582GC0.00073.FALSE
chr1811852612GT0.00410GNAL,CHMP1B+FALSE(T)nSINE,Alu
chr2112252629AC0.00107MIR4435-2HG-FALSE
chr2191745653TG0.00030GLS+FALSE
chr146076481AG0.00144NASP+TRUEAluSxSINE,Alu
chr167874859TC1.49998E-05SERBP1-TRUEAluSxSINE,Alu
chr136529575AG2.40551E-05.FALSEAluJrSINE,Alu
chr153291435AG0.00790ZYG11B+TRUEAluJrSINE,Alu
chr2152334389AG0.00308.FALSEAluSqSINE,Alu
chr985861561CT0.00287FRMD3-FALSE(TC)nSINE,Alu
chr13731965GA0.00209CEP104-FALSE
chr4165998149TC0.00057TMEM192-TRUEAluSxSINE,Alu
chr145987539CA0.00660PRDX1-FALSE
chr3195961254CT0.00119.FALSE
chr340503557TC0.00487RPL14+FALSE
chr16259025CT0.00700RPL22-FALSE
chr1100615003GA0.00046TRMT13,LRRC39+,-FALSE
chr775958147TA0.00917YWHAG-FALSE
chr116892274AT0.00371NBPF1-FALSE
chr613789470TC0.00166MCUR1-TRUEAluSgSINE,Alu
chr16283439TC0.00786ICMT-TRUEAluSx3SINE,Alu
chr12133297904AG8.99170E-13PGAM5+TRUEAluJoSINE,Alu
chr2202031356CT0.00247CFLAR+FALSESVA_ASINE,Alu
chr1541590972AG2.40282E-05OIP5-AS1+TRUEAluSx1SINE,Alu
chr1779004271TC0.00200BAIAP2-AS1-FALSEAluSq2SINE,Alu
chr16582689TC4.44823E-05NOL9-TRUEAluSgSINE,Alu
chr119542693TC0.00024LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr1110950295CA0.00359LAMTOR5-FALSE
chr1110951224AG0.00352LAMTOR5-AS1+TRUEAluJrSINE,Alu
chr2160625969TC0.00527LY75-CD302,CD302-TRUEAluSzSINE,Alu
chr7137561078GA0.00558CREB3L2-FALSE(GT)nSINE,Alu
chr171531596AG1.07667E-05ZRANB2-AS1,ZRANB2+,-FALSE
chr1235392546TC0.00312ARID4B-FALSE

Differential Expression Gene Analysis