Dataset Overview
RBPTIA1
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR057GCF
PlatformHiSeq
Pubmed ID32252787

TIA1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of TIA1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of TIA1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr12121118CT0.00234FAAP20-FALSE
chr195362953TC0.00072CNN3-FALSE
chr1352952575GA0.00030THSD1-FALSE
chr145975358AG0.00339MMACHC+TRUEAluSg7SINE,Alu
chr116534255CG0.00980ARHGEF19-FALSE
chr5149363273AG0.00114SLC26A2+TRUEAluJrSINE,Alu
chr1648386442AG0.00964LONP2,MIR5095+TRUEAluSz6SINE,Alu
chr1142619487AG0.00511.FALSE
chr1145513031AG0.00705NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1100361925GA0.00181AGL+FALSE
chr110517527TC0.00453.FALSEAluSx1SINE,Alu
chrX102613351AG0.00969TCEAL9+FALSEL1ME4aSINE,Alu
chr16583066TC0.00088NOL9-TRUEAluSx4SINE,Alu
chr116889423GC6.70783E-10NBPF1-FALSEL1MC4SINE,Alu
chr1113213009AT0.00556CAPZA1+FALSE
chr537290400TC0.00085.FALSEAluSzSINE,Alu
chr1180169330CT0.00374FLJ23867+FALSEMIRSINE,Alu
chr11345006AG1.26297E-06.FALSEAluSgSINE,Alu
chr123847464CA0.00895E2F2-FALSE
chr1226333558AC0.00722ACBD3-FALSE(CAAAA)nSINE,Alu
chr1146629399GT0.00611PRKAB2-FALSE
chr116200163AG0.00112SPEN+FALSE
chr1475202312AG3.27721E-05FCF1+TRUEAluScSINE,Alu
chr7128144035AG0.00054.FALSEAluSq2SINE,Alu
chr2217366191TA0.00306.FALSE
chr381698130TC2.93981E-08GBE1-FALSE
chr143272842AT5.93810E-05SVBP-FALSE
chr5174956493TA0.00466SFXN1+FALSE
chr310192720AG0.00110VHL+TRUEAluSx1SINE,Alu
chr2216903620TC0.00623PECR-TRUEAluSx3SINE,Alu
chr452753346AG0.00782DCUN1D4+TRUEAluScSINE,Alu
chr1098278593AT0.00792TM9SF3-FALSE
chr2146935076TG0.00164SLC19A1-FALSE
chr1214813487AG0.00027CENPF+FALSE
chr1120162635AT0.00203ZNF697-FALSE
chr7100064719AG0.00276TSC22D4-FALSE
chr5176026131AT0.00979GPRIN1-FALSE
chr1184661933GA0.00138EDEM3-FALSE
chr224225006AG0.00141.FALSEAluSxSINE,Alu
chr1153720690GA0.00786INTS3+FALSE
chr1918475356AG0.00360PGPEP1+TRUEAluSx1SINE,Alu
chr116952920GA0.00475CROCCP2-FALSE
chr43242223GA0.00073HTT+FALSE
chr145504720GC0.00759ZSWIM5-FALSE
chr1151778899TC0.00475RORC-FALSE
chr729962665CT0.00059SCRN1-FALSE
chr119542455TC0.00506LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr9137330714AC0.00030RXRA+FALSE
chr116912138AG0.00197NBPF1-FALSE
chr136770602TG0.00441THRAP3+FALSE(T)nSINE,Alu
chr3191116133CT0.00032CCDC50+FALSE
chr16283558AT0.00624ICMT-FALSE
chr796318078AT0.00790.FALSE
chr1350273970CT1.77946E-05KPNA3-FALSE
chr192976590GA0.00629EVI5-FALSE
chr11419700AG0.00671ATAD3B+TRUEAluYk2SINE,Alu
chr19644558AG0.00451.FALSEAluSxSINE,Alu
chr2178406765TA0.00325AGPS+FALSE
chr136282608GT0.00886AGO4+FALSE
chr128825331AG0.00024PHACTR4+TRUEAluSgSINE,Alu
chr1180897569CT0.00960KIAA1614+FALSE
chr2118854088CT0.00543INSIG2+FALSE
chr110520692TC0.00973DFFA-TRUEAluSc8SINE,Alu
chr1118066459AG0.00729MAN1A2+FALSE
chr1205577901GA0.00904ELK4-FALSE
chr128661692AG2.56757E-06MED18+TRUEAluSgSINE,Alu
chr3141668758TC2.84489E-05TFDP2-TRUEAluSzSINE,Alu
chr119542455TC0.00263LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr155207988GA0.00914MROH7-TTC4,TTC4+FALSE
chr413604418GC2.95746E-07BOD1L1-FALSE
chr495586224AG0.00053PDLIM5+FALSE
chr1570178GA0.00787.FALSE
chr1574319092AG0.00029PML+TRUEAluSz6SINE,Alu
chr116892276TC0.00209NBPF1-FALSE
chr1610623558TC0.00103EMP2-TRUEAluSpSINE,Alu
chr16582527TC0.00139NOL9-TRUEAluSx1SINE,Alu
chr126901090CT0.00952RPS6KA1+FALSE
chr1013320123CA0.00830PHYH-FALSE
chr1204521616AG0.00455MDM4+TRUEAluSgSINE,Alu
chr127107650TA3.71504E-05ARID1A+FALSE
chr6158093827CT0.00201ZDHHC14+FALSE
chr125775374CT0.00710TMEM57+FALSE
chr1234542410CA0.00832TARBP1-FALSE
chr2224622277TC0.00138AP1S3-TRUEAluSx1SINE,Alu
chr1165404877GA0.00106PCNX3+FALSE
chr1523313171AG0.00257HERC2P2-FALSE
chr16283260TC0.00125ICMT-TRUEAluSx3SINE,Alu
chr144447004GA0.00767B4GALT2+FALSE(CAG)nSINE,Alu
chr145975673AG0.00410MMACHC+TRUEAluSx4SINE,Alu
chr146075720AG0.00105NASP+TRUEAluSx4SINE,Alu
chr10124913908CA0.00784BUB3+FALSE
chr1109419841CT0.00057GPSM2+FALSE
chr1156495521CA0.00097IQGAP3-FALSE
chr1145369476AG0.00332NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr1169768080CA0.00980C1orf112+FALSE
chr3156258389TC0.00179SSR3-TRUEAluYk3SINE,Alu
chr642856156AG0.00190RPL7L1+TRUEAluSzSINE,Alu
chr2219100706AG0.00874ARPC2+TRUEAluSx1SINE,Alu
chr1756049829TC5.66836E-08VEZF1-TRUE
chr744841931AG0.00054PPIA+TRUEAluSxSINE,Alu
chr132799510TG0.00048MARCKSL1-FALSE
chr72650926GA0.00306IQCE+FALSE
chr9131093336TC0.00397COQ4+FALSEAluYSINE,Alu
chr147844500TG0.00169CMPK1+FALSE
chr1206557430CT0.00011SRGAP2+FALSE
chr1118167524CT0.00902FAM46C+FALSE
chr1193222534GT0.00504CDC73+FALSE(TGT)nSINE,Alu
chr1453109810TC0.00463ERO1A-TRUEMER53SINE,Alu
chr744841237TA0.00599PPIA+FALSE
chr255516891GA2.12747E-05CCDC88A-FALSE(GA)nSINE,Alu
chr238971639AT0.00019SRSF7-FALSE
chr7138732191TC0.00746ZC3HAV1-TRUEMER5BSINE,Alu
chr372425248TA0.00281RYBP-FALSE
chr895805071AG1.12730E-06DPY19L4+TRUEAluYf1SINE,Alu
chr1917412218CT0.00790ABHD8-FALSE
chr340503772TA0.00153RPL14+FALSE
chr894744813CT5.22032E-05RBM12B-FALSE
chr1145281408CT9.69497E-05NBPF20,NOTCH2NL+FALSE
chr10129910475TG0.00061MKI67-FALSE
chr1146495574CT0.00085LOC728989-FALSE
chr3196046746TC0.00513TM4SF19-TCTEX1D2,TM4SF19-AS1+,-FALSEAluSc5SINE,Alu
chr42940347TC0.00113NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr1101443701AG0.00406SLC30A7+FALSE
chr232534897AG0.00111.FALSEAluSx1SINE,Alu
chr3195404649AG0.00624SDHAP2+FALSE
chr110518720TC0.00530.FALSEAluSx1SINE,Alu
chr126449336AG0.00343PDIK1L+FALSE
chr16259025CT0.00700RPL22-FALSE
chr1590819579AG0.00933.FALSEAluSxSINE,Alu
chr127678721AG0.00030SYTL1+TRUEAluSx1SINE,Alu
chr3179116220TC0.00233GNB4-TRUEAluSz6SINE,Alu
chr2143638991AC0.00054KYNU+FALSE
chr488293887GA0.00548HSD17B11-FALSE
chr1778091513GA0.00810GAA+FALSE
chr10101992793TC0.00407CWF19L1-TRUEAluJbSINE,Alu
chr830536016TC2.97001E-06GSR-TRUEAluJrSINE,Alu
chr633385535AG0.00671.FALSE
chr11595500TC0.00482CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr2208619742AG0.00500CCNYL1+TRUEAluJbSINE,Alu
chr3136667405TC0.00190NCK1+FALSE
chr1900720AT0.00065KLHL17+FALSE(TTTA)nSINE,Alu
chr59546451GA0.00030SNHG18+FALSE
chr1593198678TC0.00064FAM174B-FALSE(GCCGCT)nSINE,Alu
chr1110040310AG2.45230E-05CYB561D1+FALSE
chr3149683506GC0.00147PFN2-FALSE
chr119543459TC0.00395LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr162627128AG2.94675E-05PATJ+TRUEAluSxSINE,Alu
chr2204162601AG0.00032CYP20A1+TRUEAluSxSINE,Alu
chr192975244TA0.00220EVI5-FALSE
chr239010088AG0.00192.FALSEAluSpSINE,Alu
chr2197004439AG0.00034STK17B-FALSE
chr631601344TC0.00569.FALSE
chr1911256703TC2.95254E-05SPC24-TRUEAluJr4SINE,Alu
chr140537918TA0.00773CAP1+FALSE
chr348787633TC0.00314PRKAR2A-TRUEAluSpSINE,Alu
chr898736864TA0.00086MTDH+FALSE
chr2201774341TC0.00073.FALSEAluSzSINE,Alu
chr299772813AG1.48642E-06LIPT1+TRUEAluSx1SINE,Alu
chr156961756AG0.00682PLPP3-FALSE
chr195658342AT0.00123TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr1142449GA0.00073.FALSEMIRbSINE,Alu
chr194423353GA0.00057CHAF1A+FALSEGA-richSINE,Alu
chr2223807622GT0.00875ACSL3+FALSE
chr12133298121AG1.85542E-11PGAM5+TRUEAluJoSINE,Alu
chr167875026AT0.00557SERBP1-FALSE
chr1234561498TC0.00092TARBP1-FALSE
chr120977748TG0.00474PINK1,PINK1-AS+,-FALSE
chr255516911AG0.00719CCDC88A-FALSE(GA)nSINE,Alu
chr138182333GT0.00063EPHA10-FALSEL2d2SINE,Alu
chr152306087CT0.00022NRDC-FALSE(TCA)nSINE,Alu
chr153680205CT9.80404E-07C1orf123-FALSE
chr1911256626TC1.61091E-07SPC24-TRUEAluJr4SINE,Alu
chr5126113463AC0.00392LMNB1+FALSE(CGACGCG)nSINE,Alu
chr1610624993TC1.49189E-05EMP2-TRUEAluSx3SINE,Alu
chr631322980CT0.00091.FALSE
chr154637167TC0.00027.FALSE
chr1230416412CG0.00514GALNT2+FALSE
chr1149581854CA0.00175LINC00623,LINC00869,LOC103091866+FALSEL2bSINE,Alu
chr121602602AG8.31525E-05ERC1+FALSEAluSxSINE,Alu
chr765844562TC0.00695LINC00174-FALSE
chr1230415244TC0.00780GALNT2+FALSE
chr47762356GA3.36293E-10AFAP1,AFAP1-AS1+,-FALSE
chr1222713503CG0.00860HHIPL2-FALSE
chr163881552CT0.00293ALG6+FALSE
chr1116235277CT0.00396VANGL1+FALSE
chr140722795GA9.35494E-07.FALSECharlie2aSINE,Alu
chr12124105948CT0.00778EIF2B1-FALSE
chr1155403823AG0.00850ASH1L,POU5F1P4+,-FALSE
chr642061234TC0.00170.FALSEAluSx1SINE,Alu
chr1160302244TC0.00310COPA-TRUE
chr1144828795CG0.00887NBPF20,NBPF9+FALSE
chr116717888GA0.00118SZRD1+FALSE
chr1207221096GA0.00452YOD1-FALSE
chr151822219GA0.00283EPS15-FALSE
chr153289892AG0.00079ZYG11B+TRUEFRAMSINE,Alu
chr16283434TC0.00285ICMT-TRUEAluSx3SINE,Alu
chr1060047612AG0.00015CISD1+FALSE(A)nSINE,Alu
chr1121133998TA0.00171SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr1145368461AC0.00542NBPF20,NBPF10+FALSE
chr1110604747GA0.00101ALX3-FALSE
chr642849746AG0.00042RPL7L1+TRUEAluSzSINE,Alu
chr146077218AG0.00543NASP+TRUEAluSc8SINE,Alu
chr1146215189GC0.00226NBPF20,NBPF10,NBPF25P+FALSE
chr237431563AG0.00993CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr5132232315GA0.00573AFF4-FALSE
chr9127711532TC0.00018SCAI-TRUEAluSpSINE,Alu
chr1197125427TC0.00331ZBTB41-FALSE
chr228002603CA0.00010MRPL33+FALSE
chr1269237077AG0.00445MDM2+TRUE(GA)nSINE,Alu
chr128608338AG0.00341SESN2+FALSE
chr1168220489AG0.00319.FALSEAluSz6SINE,Alu
chr4128756632AG0.00602.FALSEAluSxSINE,Alu
chr110517276TC0.00079.FALSEAluJrSINE,Alu
chr116933135GT2.86961E-06NBPF1-FALSEL1MC2SINE,Alu
chr115993603GA0.00103.FALSEAluSx4SINE,Alu
chr10101992298TC0.00409CWF19L1-TRUEAluSq2SINE,Alu
chr1110207639TA0.00080GSTM4+FALSE
chr422404391GA0.00338ADGRA3-FALSE
chr5149823799AT0.00672RPS14-FALSE
chr19163328TC0.00150.FALSEAluSpSINE,Alu
chr1098281480TA0.00620TM9SF3-FALSE
chr1015120306TC0.00323ACBD7-TRUEL1PA7SINE,Alu
chr119198576AG0.00542ALDH4A1-FALSE
chr72394991CT9.93448E-08EIF3B+FALSE
chr353260620TG0.00069TKT-FALSE
chr837351214TC0.00109LINC01605-FALSE
chr1168523055TC0.00524CPT1A-TRUEAluYSINE,Alu
chr116112795AG1.78234E-05FBLIM1+FALSE
chr1779674375CT0.00129MRPL12+FALSE
chr765619243AG9.04168E-05CRCP+TRUEAluSz6SINE,Alu
chr16282587TC0.00221ICMT-TRUE
chr729961659CG7.23387E-07SCRN1-FALSE
chr581571877CT0.00033RPS23-FALSE
chr1949472GA9.07885E-12ISG15+FALSE
chr775045694CT1.64957E-05NSUN5P1+FALSE
chr119543457TC0.00101LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr127181647GA0.00103ZDHHC18+FALSE
chr919063167CT0.00539HAUS6-FALSE

Differential Expression Gene Analysis