Dataset Overview
RBPSNRNP70
Knock-MethodshRNA
RBP FamilyU1snRNP70_N
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR635BOO
PlatformHiSeq
Pubmed ID32252787

SNRNP70 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of SNRNP70
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of SNRNP70


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr2025428724AG0.00033GINS1+TRUEAluJbSINE,Alu
chr2178406765TA0.00325AGPS+FALSE
chr136067677TC0.00048PSMB2-TRUEAluSzSINE,Alu
chr272968436GC0.00171EXOC6B-FALSE
chr2102484490GT0.00635MAP4K4+FALSE
chr8128944712AC0.00033PVT1+FALSE
chr127205214TC0.00799.FALSEAluScSINE,Alu
chr1207943385AG0.00751CD46+TRUEAluSx1SINE,Alu
chr510655842CT0.00024ANKRD33B+FALSE
chr1179326882AG1.03454E-05SOAT1+TRUEAluJoSINE,Alu
chr4189020293GA0.00361TRIML2-FALSE
chr128661767AG0.00242MED18+TRUEAluSgSINE,Alu
chr1186321189AG0.00010TPR-FALSE
chr143167907TC0.00072YBX1+FALSE
chr47060935GC0.00543GRPEL1-FALSETigger4aSINE,Alu
chr1741133090AT0.00148RUNDC1+FALSE
chr1220870440GA0.00193C1orf115+FALSE
chr1165404868TG0.00022PCNX3+FALSE
chr1477787088CT0.00076POMT2-FALSE
chr2197004439AG0.00034STK17B-FALSE
chr4190883001CG0.00859FRG1+FALSE
chr1173834225TC0.00105GAS5-FALSEAluSzSINE,Alu
chr117313654CT0.00714ATP13A2-FALSE
chr116912029CG0.00831NBPF1-FALSE
chr1939926509AC0.00986RPS16-FALSE
chr261276758AG0.00924PEX13+TRUEAluSpSINE,Alu
chr314526648TG9.03719E-05SLC6A6+FALSE
chr553840199GT0.00857SNX18+FALSE
chr5180236449GC0.00011MGAT1-FALSE
chr1247319707CT3.10675E-05ZNF124-FALSE
chr255459824CT0.00786RPS27A+FALSE
chr11345002AG0.00141.FALSEAluSgSINE,Alu
chr116890672GA0.00142NBPF1-FALSE
chr1220231347TC2.85871E-07RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr110518733TC0.00952.FALSEAluSx1SINE,Alu
chr1165404877GA0.00106PCNX3+FALSE
chr195362514GT0.00658CNN3-FALSE
chr197144546AC0.00803.FALSE
chr224224134AG0.00333.FALSEAluSpSINE,Alu
chr348787118TC0.00359PRKAR2A-TRUEAluSx3SINE,Alu
chr16282400TC0.00385ICMT-TRUEAluSzSINE,Alu
chr1150548883AC0.00255MCL1-FALSE
chr192862879AG3.90108E-09.FALSEAluJrSINE,Alu
chr1773940167TC0.00035ACOX1-TRUEAluJbSINE,Alu
chr110521130TC0.00860DFFA-TRUEAluYSINE,Alu
chr848889672AG0.00091MCM4+TRUEAluSx3SINE,Alu
chr1911256702TC6.98885E-06SPC24-TRUEAluJr4SINE,Alu
chr239009427AG0.00673.FALSEAluSx3SINE,Alu
chr1226171400TC0.00359SDE2-TRUEBC200SINE,Alu
chr1016554733GT0.00706PTER+FALSE
chr553841240AG0.00416SNX18+FALSE
chr146076543AG0.00989NASP+TRUEAluSxSINE,Alu
chr126755229AG0.00318LIN28A+FALSEAluSx1SINE,Alu
chr110517352TC0.00050.FALSEAluJrSINE,Alu
chr119585554AG2.15626E-06MRTO4+TRUEAluSc8SINE,Alu
chr119953132CA0.00910MINOS1,MINOS1-NBL1+FALSE
chr145226084GA0.00970KIF2C+FALSE
chr2112252464GA2.95640E-06MIR4435-2HG-FALSE
chr136535590AG0.00301.FALSEAluSx1SINE,Alu
chr111346336AG0.00288UBIAD1+FALSE
chr13114748384CT0.00050RASA3-FALSE
chr2234385276TC0.00951USP40-FALSE
chr138327584TC0.00017INPP5B-TRUEAluSx3SINE,Alu
chr652226984GA0.00127PAQR8+FALSE(GCTCGG)nSINE,Alu
chr347628810TA0.00934SMARCC1-FALSE
chr19331254AG0.00793H6PD+TRUEAluSxSINE,Alu
chr2025428646AG9.98122E-05GINS1+TRUEAluJbSINE,Alu
chr133148736AG0.00525SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr220818286AC0.00714HS1BP3-FALSE
chr1100550370TA0.00308SASS6-FALSE
chr16314743CT6.72719E-05GPR153-FALSE
chr9131093963AG0.00299COQ4+TRUEAluJoSINE,Alu
chr2206981487TC0.00281.FALSEAluSgSINE,Alu
chr1184663537AC0.00256EDEM3-FALSE
chr4109551183TA0.00270RPL34+FALSE
chr124999635AG0.00602SRRM1+FALSE
chr146828700AG0.00093NSUN4+FALSE
chr365341374TA0.00029MAGI1-FALSE
chr1256345408TG0.00885DGKA+FALSE
chr6150046484TC0.00953NUP43-TRUEAluSq2SINE,Alu
chr540830050TC0.00042.FALSEAluSpSINE,Alu
chr7107788257CT0.00068NRCAM-FALSE
chr140361783GC0.00023MYCL-FALSE
chr72473761TC0.00126CHST12+FALSE(CCGC)nSINE,Alu
chr1144618201TC2.48995E-05NBPF20,NBPF9+FALSE
chr1145689537AG0.00593NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr16282315TC5.02629E-05ICMT-TRUEAluSzSINE,Alu
chr2118583874CG0.00569DDX18+FALSE
chr362189314CT0.00018PTPRG+FALSE
chr1109242607GA0.00652PRPF38B+FALSE
chr1120611964GC0.00077NOTCH2-FALSE
chr141326886CG0.00085CITED4-FALSE
chr177123232CG0.00250DLG4,ACADVL+,-FALSE
chr246612338TG0.00018EPAS1+FALSE
chr644417142AG0.00020CDC5L+TRUEFLAM_CSINE,Alu
chr1109746825AG0.00094KIAA1324+TRUEAluJbSINE,Alu
chr139990456GA0.00749BMP8A,PPIEL+,-FALSEL2bSINE,Alu
chr1114940209GT0.00177TRIM33-FALSE(T)nSINE,Alu
chr153359181AG0.00699ZYG11A+TRUEAluSxSINE,Alu
chr16583383TC0.00305NOL9-TRUEAluSqSINE,Alu
chr195362514GT7.06346E-05CNN3-FALSE
chr167896025GA5.77574E-06SERBP1-FALSE
chr2128604232AT0.00652POLR2D-FALSE
chr1145509493AG0.00264NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chrX54587290AG0.00504GNL3L+TRUEAluSq2SINE,Alu
chr3195242996CA0.00136PPP1R2-FALSE
chr1193466866GT0.00559MIR1304-FALSEAluJrSINE,Alu
chr1269160464AG0.00041.FALSEAluJbSINE,Alu
chr830536016TC2.97001E-06GSR-TRUEAluJrSINE,Alu
chr1220231461TC0.00050RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr177124772GA0.00175ACADVL+FALSE
chr165330637CT0.00047JAK1-FALSE
chr133086905TC0.00598ZBTB8OS-FALSEAluYSINE,Alu
chr1110566210TA0.00832AHCYL1+FALSE
chr16283348TC0.00247ICMT-TRUEAluSx3SINE,Alu
chr1114455907GA0.00705DCLRE1B+FALSE
chr1212459257AG0.00068PPP2R5A+FALSE
chr265432447CT0.00486.FALSE
chr190497768AG4.54321E-06ZNF326+TRUE
chr133148367CG0.00439SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr5150647744AG0.00036GM2A+TRUEAluScSINE,Alu
chr1256510709GA0.00047RPL41+FALSE
chr111979815AC0.00072KIAA2013-FALSE
chr11595048TC0.00251CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr2191556849AT0.00158NAB1+FALSE
chr633385535AG0.00671.FALSE
chr116890130AC0.00753NBPF1-FALSE
chr11251841TC0.00222CPSF3L-TRUEAluSq2SINE,Alu
chr29629304AG0.00121ADAM17-FALSE
chr1208198625CT8.83580E-05PLXNA2-FALSE
chr19160900TC0.00628.FALSEAluJbSINE,Alu
chr1916663345TC0.00304SLC35E1-TRUEAluSgSINE,Alu
chr4248996AG0.00123ZNF876P+TRUEAluYk3SINE,Alu
chr5203683GT0.00399.FALSEMIRbSINE,Alu
chr16282224TC0.00785ICMT-TRUEAluSzSINE,Alu
chr124289057GC0.00044PNRC2+FALSE
chr7100860467CG0.00267PLOD3-FALSE
chr23502625TC0.00800ADI1-FALSE
chr116096934CT0.00336FBLIM1+FALSE
chr116902943TC0.00833NBPF1-FALSE
chr1114940216TG0.00674TRIM33-FALSE(T)nSINE,Alu
chr144818526CG0.00326ERI3-FALSE
chr2109401283CT0.00039RANBP2+FALSE
chr119246181AG1.12993E-05IFFO2-FALSE
chr1149913727TC1.10479E-05OTUD7B-TRUEMER96BSINE,Alu
chr1623478710CA0.00335GGA2-FALSE(AC)nSINE,Alu
chr229170763GA5.21672E-05WDR43+FALSE
chr525415881TC0.00911.FALSE
chr4120378207AG8.04303E-06LOC645513+FALSE
chr120811795GC0.00047CAMK2N1-FALSE
chr1569874CT0.00072.FALSE
chr192917287CA0.00243ZNF57+FALSE
chr16282401TC1.82955E-05ICMT-TRUEAluSzSINE,Alu
chr133148210AG0.00114SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1101444065TC0.00927SLC30A7+FALSEMIR3SINE,Alu
chr143394666GA0.00224SLC2A1-FALSE
chr1145512078AG0.00099NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr2227597207TC0.00209IRS1-FALSE(TA)nSINE,Alu
chr110520725TC0.00795DFFA-TRUEAluSc8SINE,Alu
chr116203172AG8.98827E-07SPEN+FALSE
chr629910586GA1.69263E-05.FALSE
chr1567191CT0.00428.FALSE
chr456298300GA7.51019E-06CLOCK-FALSE
chr136067925TC1.59250E-07PSMB2-TRUEAluSzSINE,Alu
chr237329214TC0.00081.FALSEAluJr4SINE,Alu
chr119586455AG3.44081E-06MRTO4+TRUEAluSzSINE,Alu
chr830536606TC9.30891E-05GSR-TRUEAluSpSINE,Alu
chr110519946TC0.00401.FALSEAluJrSINE,Alu
chr1142804438GT0.00618.FALSE
chr2218571345AG0.00113PEX26+TRUEAluSzSINE,Alu
chr727237453CT0.00421HOXA13-FALSE
chr1162497663GA0.00335UHMK1+FALSE
chr5141691255CA0.00323SPRY4-FALSE
chr8128944717GT0.00091PVT1+FALSE
chr110093749TC0.00521UBE4B+FALSE
chr46644327AG0.00000MRFAP1+FALSE
chr76501830GA0.00110KDELR2-FALSE
chr5175934037CA0.00182FAF2+FALSEA-richSINE,Alu
chr45710647AG5.78692E-06EVC2-FALSE
chr210711446TC0.00014NOL10-FALSEMSTASINE,Alu
chr1184762524TC0.00471FAM129A-TRUEAluSzSINE,Alu
chr125894466AC0.00783LDLRAP1+FALSEMIRbSINE,Alu
chr11344998AG0.00235.FALSEAluSgSINE,Alu
chr1075009651TC0.00558DNAJC9-AS1,MRPS16+,-FALSEAluScSINE,Alu
chr1109816293GC0.00759CELSR2+FALSE
chr16314822TC0.00300GPR153-FALSE
chr116254872CA4.87895E-08SPEN+FALSE
chr135817023GC0.00547ZMYM4+FALSE
chr125169634AG0.00843CLIC4+FALSE
chr1757279282AG7.34157E-06PRR11+TRUEAluSq2SINE,Alu
chr477996987TC0.00240CCNI-FALSE
chr135817022TA0.00072ZMYM4+FALSE
chr1241796948TC0.00082OPN3,CHML-FALSE
chr564964627TC0.00998SGTB-TRUEAluSx1SINE,Alu
chr119542458TC1.01966E-05LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1160965379TC0.00477F11R-TRUEAluScSINE,Alu
chr1194606941TC0.00699AMOTL1+FALSE
chr4178256913CG4.41796E-05NEIL3+FALSE
chr1111682307GC5.71833E-05DRAM2,CEPT1+,-FALSE
chr140219280TC8.82951E-05PPIE+FALSE
chr19161366TC0.00189.FALSEAluSxSINE,Alu
chr315114759GA0.00595RBSN-FALSE
chr185488830TC0.00137MCOLN3-TRUEAluJrSINE,Alu
chr1210006603CT0.00829DIEXF+FALSE
chr121611799AG0.00156LINC00942+FALSE
chr799017241CA0.00721PTCD1,ATP5J2-PTCD1-FALSE
chr3122283294GC0.00066DTX3L,PARP9+,-FALSE
chr120976078TC0.00344PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr128826118AG0.00948PHACTR4+TRUEAluJbSINE,Alu
chr118709240AG0.00431RPL27A+TRUEAluYk2SINE,Alu
chr393846831GA0.00547.FALSEAluSq2SINE,Alu
chr1246714587GA0.00023TFB2M-FALSE
chr7102004748TC0.00050LOC100289561,LOC100630923+FALSE
chr1118167515CT0.00852FAM46C+FALSE
chr286249840TC0.00482LOC90784-TRUEAluJrSINE,Alu
chr63114457CT0.00320RIPK1+FALSE
chr3110853822GT0.00812NECTIN3+FALSE
chr320195395CT3.65176E-06KAT2B+FALSE
chr19788153GA0.00198PIK3CD+FALSEAluSxSINE,Alu
chr2217366444AG2.40359E-05.FALSE
chr236776057AG0.00034CRIM1+FALSE
chr110520076TC0.00763.FALSEAluSxSINE,Alu
chr147716042AT0.00574STIL-FALSE
chr1591044379TG0.00440IQGAP1+FALSE
chr133149496AG0.00662SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr5130494984AT0.00018HINT1-FALSE
chr237331531TC0.00389.FALSEAluJbSINE,Alu
chr8145159708AG0.00101MAF1+FALSE
chr133149400AG0.00026SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr314986138TC1.80576E-11FGD5-AS1-TRUEFLAM_CSINE,Alu
chr11594498CT0.00024CDK11B,SLC35E2B-FALSE
chr271376999GA0.00546MPHOSPH10+FALSE
chr2114352179GA1.68965E-05WASH2P+FALSE
chr1205320469GA0.00109KLHDC8A-FALSE
chr349395757GA3.97123E-06GPX1-FALSE
chr128566461TC1.61071E-05.FALSEAluSx1SINE,Alu
chr6109785887TC7.14632E-06MICAL1,ZBTB24-TRUEAluJrSINE,Alu
chr1110566328AT0.00515AHCYL1+FALSE
chr128826150AG0.00048PHACTR4+TRUEAluJbSINE,Alu
chr133086758TC0.00818.FALSEAluYSINE,Alu
chr2175711942CT8.43847E-05CHN1-FALSE
chr4128995640GA0.00567LARP1B+FALSE
chr173561396CT0.00322CTNS+FALSE
chr310192838AG1.36876E-05VHL+TRUEAluSx1SINE,Alu
chr3112720120TG0.00573GTPBP8+FALSE
chr116890130AC0.00412NBPF1-FALSE
chr1153617973AG4.00129E-07CHTOP+FALSE
chr1953914395AG0.00227ZNF765+TRUEAluSxSINE,Alu
chr2129024313AG0.00612HS6ST1-FALSE
chr1182356399AG0.00740GLUL-FALSE
chr744842429TG0.00384PPIA+FALSE
chr13545198TC0.00013TPRG1L+FALSE
chr1200521412GA0.00110KIF14-FALSE
chr1757279284AG0.00149PRR11+TRUEAluSq2SINE,Alu
chr1101541172AG6.48917E-05LOC102606465+TRUEMLT1KSINE,Alu
chr1194903795GT0.00328SESN3-FALSE
chr2219134117CT0.00357AAMP-FALSE
chr19163402TC4.95479E-05.FALSEAluSpSINE,Alu
chr3100467676AT0.00067TFG+FALSE
chr1144932199CA0.00584NBPF20,PDE4DIP+,-FALSE
chr114604AG0.00304WASH7P-FALSE
chr136067760TC0.00203PSMB2-TRUEAluSzSINE,Alu
chr1567783TC0.00427MIR6723-FALSE
chr13697550CA0.00078LRRC47-FALSEAluScSINE,Alu
chr145975628AG0.00465MMACHC+TRUEAluSx4SINE,Alu
chr261386572CG0.00821C2orf74+FALSEAluSzSINE,Alu
chr16683581AC0.00189PHF13+FALSE
chr5177019196GC0.00509TMED9+FALSE(GCG)nSINE,Alu
chr120976163CT0.00091PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr197543764CT0.00353DPYD-FALSE
chr110521254TC0.00522DFFA-TRUEAluYSINE,Alu
chr135886030TC0.00606ZMYM4+FALSE
chr531553968TC0.00555C5orf22+FALSE
chr314528004TC0.00091SLC6A6+FALSE
chr3181430454GA0.00577SOX2-OT,SOX2+FALSE
chr3113604709TC0.00012GRAMD1C+FALSE
chr144818549CT0.00108ERI3-FALSE
chr1492585231TC0.00023NDUFB1-TRUEAluSgSINE,Alu
chr145280109AG0.00251.FALSEAluYk3SINE,Alu
chr1116609185GA0.00187SLC22A15+FALSE
chr765618876AG0.00817CRCP+TRUEAluSx3SINE,Alu
chr146828734TC0.00604NSUN4+FALSE
chr652860743TG1.89710E-05.FALSE7SKSINE,Alu
chr1205687354TC0.00012NUCKS1-FALSE(T)nSINE,Alu
chr147099235AC0.00919.FALSE
chr116944809GC9.47535E-05CROCCP2-FALSE
chr11650845GA0.00094CDK11B,CDK11A-FALSE
chr3149237753GA2.17555E-05WWTR1-FALSEAluSq2SINE,Alu
chr1150703860TC0.00222CTSS-TRUEAluSxSINE,Alu
chr167874696TC0.00014SERBP1-TRUEAluSx3SINE,Alu
chr3195243012AC0.00128PPP1R2-FALSE
chr274348998AG0.00279.FALSEAluSzSINE,Alu
chr1541593308AG0.00619.FALSEAluSz6SINE,Alu
chr153291382AG0.00132ZYG11B+TRUEAluJrSINE,Alu
chr1120163247TC0.00365ZNF697-FALSE
chr12102517753TC0.00022PARPBP+FALSE
chr153289686AG0.00460ZYG11B+TRUEAluSzSINE,Alu
chr16283296TC0.00225ICMT-TRUEAluSx3SINE,Alu
chr146075192AC0.00045NASP+FALSEA-richSINE,Alu
chr133146255CA0.00182SYNC,RBBP4+,-FALSE
chr2101622887GA0.00711RPL31+FALSE
chr1110207639TA0.00080GSTM4+FALSE
chr128826085AG0.00281PHACTR4+TRUEAluJbSINE,Alu
chr116921146TC0.00382NBPF1-FALSE
chr4110635486AG0.00021PLA2G12A-FALSE
chr1227071525CT0.00013PSEN2+FALSE
chr16282426TC0.00043ICMT-TRUEAluSzSINE,Alu
chr466439707TC0.00148EPHA5-FALSE
chr1244871041TA0.00590DESI2+FALSE
chr133148284AG0.00793SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr132669918GA0.00344CCDC28B+FALSE
chr4103718454TA0.00446LOC102723704,UBE2D3+,-FALSE
chr1226923264GA0.00046ITPKB-FALSE
chr353319203CG0.00453DCP1A-FALSE
chr224225006AG0.00141.FALSEAluSxSINE,Alu
chr540832548AT0.00048RPL37-FALSE
chr110368093CA0.00131KIF1B+FALSE
chr224223256AG0.00711UBXN2A+TRUEAluScSINE,Alu
chr657034842TG0.00581ZNF451,LOC101927211+,-FALSE
chr1921302045AG0.00020ZNF714+TRUEAluSg4SINE,Alu
chr1145688682AC0.00468NBPF20,NBPF10,RNF115+FALSE
chr350150360AG0.00651RBM5+TRUEAluSxSINE,Alu
chr1120695197GA2.17750E-05.FALSE
chr18412989AG0.00190RERE-FALSE
chrX77083939TC5.71267E-05MAGT1-TRUEAluSzSINE,Alu
chr19643028AG0.00017.FALSEAluSxSINE,Alu
chr5125962169AG0.00013PHAX+TRUEAluScSINE,Alu
chr1245006499CG0.00238COX20+FALSE

Differential Expression Gene Analysis