Dataset Overview
RBPHNRNPU
Knock-MethodshRNA
RBP FamilySAP
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR308IKH
PlatformHiSeq
Pubmed ID32252787

HNRNPU - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of HNRNPU
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of HNRNPU


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr237329261TC0.00123.FALSEAluJr4SINE,Alu
chr116890639CT8.47214E-05NBPF1-FALSE
chr110520487TC0.00710.FALSEAluSx1SINE,Alu
chr9111781015AC0.00853TMEM245-FALSE
chr3195963397GA0.00037.FALSE
chr1757279273AG0.00513PRR11+TRUEAluSq2SINE,Alu
chr11118888992CG0.00222RPS25-FALSE
chr716640491GA0.00478ANKMY2-FALSE
chr565120054CT0.00625NLN+FALSE
chr5150647719TC0.00112GM2A+FALSEAluScSINE,Alu
chr120978024CA0.00175PINK1-AS-FALSE
chr3120128940AG0.00434FSTL1-FALSE
chr120977748TG0.00474PINK1,PINK1-AS+,-FALSE
chr1569874CT0.00072.FALSE
chr1610624966TC3.33519E-08EMP2-TRUEAluSx3SINE,Alu
chr128826128AG0.00483PHACTR4+TRUEAluJbSINE,Alu
chr175336210TC0.00868RPAIN,C1QBP+,-FALSE
chr1148595665AG0.00141NBPF15+TRUEL1MC4SINE,Alu
chr568936027GA0.00868.FALSE
chrX123045407AG0.00153XIAP+TRUEAluJoSINE,Alu
chr144171144TA0.00108KDM4A-AS1,KDM4A+,-FALSE
chr629911284TC0.00019.FALSE
chr2134729969AG0.00077IFNAR1+TRUEAluSg7SINE,Alu
chr123636277AT0.00188HNRNPR-FALSE
chr168940887TG0.00293DEPDC1-FALSEMIRSINE,Alu
chr315114486TC3.99101E-05RBSN-TRUEAluYSINE,Alu
chr146165408TC0.00106IPP-TRUEFRAMSINE,Alu
chr12133334739TC0.00388ANKLE2-TRUEAluSzSINE,Alu
chr29770610AG0.00486YWHAQ-FALSE
chr1161559466CA0.00491FCGR2C+FALSE
chr642048128GT0.00604TAF8+FALSEAluSq2SINE,Alu
chr1145689566AG0.00331NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr17828190AC0.00049CAMTA1+FALSE(A)nSINE,Alu
chr328390351AG0.00200AZI2-FALSE
chr345722253AG0.00663LIMD1,LIMD1-AS1+,-FALSEAluSzSINE,Alu
chr138326728TC0.00079INPP5B-TRUEAluJrSINE,Alu
chr4190881971AC0.00183FRG1+FALSE
chr312942852CA0.00458IQSEC1-FALSE
chr2134728113AG0.00531IFNAR1+TRUEAluScSINE,Alu
chr1256632550GA0.00027ANKRD52-FALSE
chr128825331AG0.00024PHACTR4+TRUEAluSgSINE,Alu
chr1204521580AG0.00469MDM4+TRUEAluSgSINE,Alu
chr117733268TC0.00472RCC2-FALSE
chr1241796950CA1.24743E-05OPN3,CHML-FALSE
chr119543353TC0.00036LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr2215674224GA9.97816E-05BARD1-FALSE
chr1824127008TG0.00800KCTD1-FALSE(TGG)nSINE,Alu
chr155619569CT0.00477USP24-FALSE
chr3148748197TA0.00026HLTF-FALSE
chr114113455GA0.00647PRDM2+FALSE
chr1120165040TC0.00107ZNF697-FALSE
chr165900357GT0.00041LEPR,LEPROT+FALSE
chr627327349CG0.00359ZNF204P-FALSE
chr1206566948GA0.00228SRGAP2+FALSE
chr417804740TC0.00015DCAF16-TRUEAluSxSINE,Alu
chr1464152516TC0.00011SGPP1-FALSE(TA)nSINE,Alu
chr1624807247GA0.00417TNRC6A+FALSE
chr116932931CA0.00191NBPF1-FALSEL1MC2SINE,Alu
chr1203277253AG0.00624BTG2+FALSE
chr7924639AG0.00285GET4+TRUEAluJbSINE,Alu
chr932425898TC0.00177ACO1+FALSE
chr16659505GA0.00405KLHL21-FALSE
chr116952481AG5.15865E-05CROCCP2-FALSE
chr128825370AG0.00617PHACTR4+TRUEAluSgSINE,Alu
chr7131188652GC0.00684PODXL-FALSEMIR3SINE,Alu
chr136067760TC0.00258PSMB2-TRUEAluSzSINE,Alu
chr1183218868TG0.00091NMNAT2-FALSE
chr4165998019TC0.00849TMEM192-TRUEAluSxSINE,Alu
chr1200375005AT0.00202ZNF281-FALSE
chr11667419AC0.00028SLC35E2-FALSEAluSgSINE,Alu
chr12120898728AG0.00947GATC+TRUEAluYSINE,Alu
chr11595500TC0.00845CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr168167532AC0.00916GNG12-FALSE
chr244459528GA0.00100PPM1B+FALSE
chr116889620TC0.00884NBPF1-FALSE
chr936216895TC0.00130GNE-TRUEAluYSINE,Alu
chr121793735CG0.00405NBPF3+FALSE
chr42940371TC0.00150NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr136068370TC0.00067PSMB2-TRUEAluScSINE,Alu
chr153679610GA0.00217CPT2+FALSEAluSzSINE,Alu
chr345960556CT0.00500FYCO1-FALSE
chr237431521AG0.00783CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr119071752TC0.00503PAX7+FALSE
chr1214531239CT6.46771E-05PTPN14-FALSE
chr344791343TC0.00220KIAA1143-FALSEAluJrSINE,Alu
chr2118940466AT0.00169CXADR+FALSEAluYSINE,Alu
chr158999651TG0.00980OMA1-FALSE
chr345722253AG0.00670LIMD1,LIMD1-AS1+,-FALSEAluSzSINE,Alu
chr16694574GA0.00983THAP3,DNAJC11+,-FALSE
chr121766776GC0.00343NBPF3+FALSE
chr174672926TA0.00159FPGT-TNNI3K,FPGT+FALSEKanga1dSINE,Alu
chr187811105GA0.00025LMO4+FALSE
chr116958833TA0.00765.FALSE
chr1144930596CA0.00578NBPF20,PDE4DIP+,-FALSE
chr156961756AG0.00682PLPP3-FALSE
chr4185309400TA0.00250IRF2-FALSE(GGGAT)nSINE,Alu
chr1681064629AG6.04166E-07CENPN+TRUEAluSgSINE,Alu
chr115992470GA0.00605.FALSE
chr133148691AG0.00032SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr3197682724TA0.00556IQCG-FALSE
chr2242212177CT2.31719E-05HDLBP-FALSE
chr417629934TC0.00178.FALSEMER90SINE,Alu
chr286364707GT0.00131PTCD3+FALSE
chr126143725AT0.00920SEPN1+FALSEAluSxSINE,Alu
chr132638906CT5.73102E-10KPNA6+FALSE
chr631324202TA0.00300.FALSE
chr110520378TC0.00743.FALSEAluSx1SINE,Alu
chr27036682AT0.00335RSAD2+FALSE
chr128835934AG0.00596SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr738764332TC0.00209VPS41-TRUEAluSpSINE,Alu
chr110521170TC0.00104DFFA-TRUEAluYSINE,Alu
chr116893763TC0.00996NBPF1-FALSE
chr1120695202CA0.00033.FALSE
chr11650807TC0.00096CDK11B,CDK11A-FALSE
chr4159176109CA0.00042TMEM144+FALSEMIRSINE,Alu
chr1184762524TC0.00778FAM129A-TRUEAluSzSINE,Alu
chr119543353TC0.00101LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1118066459AG0.00788MAN1A2+FALSE
chr111347155CT0.00273UBIAD1+FALSE
chr791742141TA0.00620CYP51A1-FALSEAluSx3SINE,Alu
chr3195961254CT0.00119.FALSE
chr1225974645AG0.00984SRP9+TRUEAluJrSINE,Alu
chr1206637133CT0.00909SRGAP2+FALSE
chr1186946912GA0.00414PLA2G4A+FALSE
chr119543465TC0.00117LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr4120219239TA0.00707C4orf3-FALSE
chr12161135AG0.00028SKI+FALSE
chr576371820AG0.00162.FALSE
chr167468124GC0.00201SLC35D1-FALSE
chr1742880190TC0.00284GJC1-TRUEAluJbSINE,Alu
chr1114940216TG0.00674TRIM33-FALSE(T)nSINE,Alu
chr126887592TC0.00354RPS6KA1+FALSE
chr159148136TC0.00244MYSM1-FALSE
chr146016687TC0.00296AKR1A1+FALSE
chr1201975173GT0.00053RNPEP+FALSE
chr3105294534AG1.10929E-06ALCAM+FALSE
chr119232017TG0.00723IFFO2-FALSE
chr224224134AG0.00333.FALSEAluSpSINE,Alu
chr1179832838AG0.00018TOR1AIP2-FALSEMLT1LSINE,Alu
chr1109856391GC0.00569SORT1-FALSE
chr127204865TC0.00042.FALSEAluSxSINE,Alu
chr127992800CA5.71645E-05IFI6-FALSEFAMSINE,Alu
chr153288862AG0.00155ZYG11B+TRUEAluJoSINE,Alu
chr310192784AG1.73909E-05VHL+TRUEAluSx1SINE,Alu
chr1788840TC0.00299LINC01128+FALSE
chr227279013AG6.08626E-07AGBL5+FALSE
chr6134492485CT0.00245SGK1-FALSE
chr344791398TC0.00204KIAA1143-TRUEAluJrSINE,Alu
chr766105163CG0.00594KCTD7+FALSE
chr1957804362GA0.00191ZNF460+FALSE
chr12123346997GC0.00275HIP1R+FALSE
chr16282237TC0.00455ICMT-TRUEAluSzSINE,Alu
chr1144606963GT0.00337NBPF20+FALSE
chr116935130CT0.00288NBPF1-FALSE
chr10101992810TC0.00456CWF19L1-TRUEAluJbSINE,Alu
chr1160966351TC0.00034F11R-TRUEAluSgSINE,Alu
chr5154196577CT0.00906LARP1+FALSE
chr140538317CA0.00178CAP1+FALSE
chr110517313TC0.00015.FALSEAluJrSINE,Alu
chr340353799GT0.00906EIF1B+FALSE
chr1156878044GA9.48586E-05PEAR1+FALSE
chr35258236GC3.37681E-06EDEM1+FALSE
chr19161179TC0.00570.FALSEAluSxSINE,Alu
chr144818549CT0.00108ERI3-FALSE
chr315112631AG0.00019RBSN-FALSE
chr315114486TC0.00342RBSN-TRUEAluYSINE,Alu
chr1089004545TC0.00057NUTM2A-AS1-FALSEMSTASINE,Alu
chr119586532AG0.00166MRTO4+TRUEAluSzSINE,Alu
chr1226171340TC0.00462SDE2-TRUEBC200SINE,Alu
chr9117050998GA0.00326COL27A1+FALSE
chr1144595943AG0.00050NBPF20+FALSEAluJbSINE,Alu
chr6122765962TA0.00362SERINC1-FALSE
chr16282587TC7.24363E-07ICMT-TRUE
chr1152187183CA0.00373HRNR-FALSE
chr119543249TC0.00559LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1155161736GA0.00088MUC1-FALSE
chr9131872860CT0.00141CRAT-FALSE
chr1065382718GA0.00984REEP3+FALSEAluScSINE,Alu
chr1738798073TG0.00692SMARCE1-FALSE
chr347554503TG0.00720ELP6-FALSEAluSxSINE,Alu
chr1155851620AG6.99218E-05SYT11+TRUEAluSq2SINE,Alu
chr76500726AT0.00560KDELR2-FALSE
chr344791293AT0.00031KIAA1143-FALSEAluJrSINE,Alu
chr1653525857AG0.00093AKTIP-FALSE
chr1150448374TA0.00607RPRD2+FALSE
chr9132268359AG0.00436LINC00963+TRUEAluJbSINE,Alu
chr116889423GC6.70783E-10NBPF1-FALSEL1MC4SINE,Alu
chr152253793CT0.00966OSBPL9+FALSE
chr12109887765TG0.00091KCTD10-FALSE
chr348894565TA0.00142SLC25A20-FALSE
chr126603883GA0.00088CEP85+FALSE
chr11251847TC0.00999CPSF3L-FALSEAluSq2SINE,Alu
chr358112440AG8.00661E-07FLNB+FALSE
chr2236677551TC7.06365E-05MYH9-FALSE
chr133960062AG0.00064ZSCAN20+FALSE
chr1950410816GT0.00050IL4I1,NUP62-FALSEAluSzSINE,Alu
chr145671430AT0.00041ZSWIM5-FALSE
chr449591495GC0.00893.FALSE
chr116529016CT0.00024ARHGEF19-FALSE
chr147840938AG0.00089CMPK1+FALSE
chr11152601AG0.00075SDF4-FALSE
chr9102977295CT3.70755E-05INVS+FALSEHERVL40-intSINE,Alu
chr136067760TC0.00021PSMB2-TRUEAluSzSINE,Alu
chr337407770GT0.00530GOLGA4+FALSE
chr108116464GA0.00695GATA3+FALSEA-richSINE,Alu
chr1165404877GA0.00106PCNX3+FALSE
chr146165437TC0.00090IPP-TRUEFRAMSINE,Alu
chr2103333654AT0.00488MFSD9-FALSEAluYm1SINE,Alu
chr154691922TA0.00224SSBP3-FALSE
chr115993713AT7.45571E-05.FALSEAluSx4SINE,Alu
chr124934236AG0.00596NCMAP+TRUEAluSz6SINE,Alu
chr1935741552CT0.00165LSR+FALSE
chr717384440AG0.00271AHR+TRUEAluSxSINE,Alu
chr111084103TA0.00118TARDBP+FALSE
chr572801329TA0.00073BTF3+FALSE
chr45710647AG5.78692E-06EVC2-FALSE
chr42940164TC0.00115NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr119543356TC0.00256LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr123636277AT0.00295HNRNPR-FALSE
chr6114178851TC0.00056MARCKS+FALSE(TGCCGC)nSINE,Alu
chr540826638CA0.00749LOC100506548-FALSELTR78SINE,Alu
chr7105162638GC0.00155PUS7-FALSE
chr5149363219AG0.00866SLC26A2+FALSEAluJrSINE,Alu
chr41387223AG0.00155CRIPAK+TRUEAluSxSINE,Alu
chr1109818162TC0.00253CELSR2+FALSE
chr128218100TC0.00080RPA2-FALSE
chr9125609940TA0.00044.FALSE
chr146075664AG0.00842NASP+TRUEAluSx4SINE,Alu
chr211323078CT0.00539ROCK2-FALSE
chr5177019196GC0.00509TMED9+FALSE(GCG)nSINE,Alu
chr151873951GA0.00588EPS15-FALSE
chr16695423TG9.25675E-05THAP3,DNAJC11+,-FALSE
chr642856100AG0.00048RPL7L1+TRUEAluSzSINE,Alu
chr237330606TC0.00136.FALSEAluSq2SINE,Alu
chr1112003958TA0.00557ATP5F1+FALSEHelitron2Na_MamSINE,Alu
chr11337737GC2.51903E-05MRPL20-FALSE
chr285776644TC0.00127GGCX-TRUEAluSz6SINE,Alu
chr1541597484AG0.00619.FALSEAluSz6SINE,Alu
chr1205111761AC0.00497DSTYK-FALSE
chr2176789423CA0.00441LNPK-FALSEMSTB1SINE,Alu

Differential Expression Gene Analysis