Dataset Overview
RBP
LSM11
Knock-Method
shRNA
RBP Family
LSM
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR883BXR
Platform
HiSeq
Pubmed ID
32252787
LSM11 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of LSM11
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A2M
1827.0
2056.18
0.22282
0.00430
0.02396
AAMDC
20.94
27.61
0.35069
0.03774
0.11944
AATK
2.13
1.52
-0.63649
0.00546
0.02885
ABC7-42389800N19.1
12.05
8.21
-0.55389
0.00035
0.00349
ABCA1
19.68
23.09
0.22928
0.00598
0.03089
ABCA11P
3.52
4.6
0.42055
0.02113
0.07911
ABCA2
15.39
7.18
-0.69625
4.88633E-08
1.88852E-06
ABCA5
6.23
7.44
0.33082
0.01235
0.05296
ABCA7
17.17
12.29
-0.61633
1.38870E-08
6.09827E-07
ABCA8
0.63
0.67
1.00599
0.00358
0.02069
Showing 1 to 10 of 4,504 entries
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Function Analysis of Target Genes of LSM11
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52642377_52642465_52619601_52619745_52645340_52645387
0.00462
0.041
DataSet_01_19
View details
ABHD14A-ACY1
52020968_52021212_52020620_52020677_52021324_52021469
0.00770
-0.2
DataSet_01_19
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ACSL3
223765391_223765498_223752547_223752606_223773450_223773754
0.00116
0.095
DataSet_01_19
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ADD1
2928368_2928402_2927740_2927839_2929897_2931789
0.00009
0.09
DataSet_01_19
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ADD1
2928365_2928402_2927740_2927839_2929897_2931054
0.00043
0.07
DataSet_01_19
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AFP
74320952_74321007_74319481_74319614_74321347_74321891
0.00006
-0.008
DataSet_01_19
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AFP
74310709_74310839_74309063_74309161_74315051_74315184
0.00553
-0.011
DataSet_01_19
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AHSA2
61413114_61413216_61412636_61412753_61413580_61413632
0.00008
0.199
DataSet_01_19
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AHSG
186337645_186337702_186336285_186336426_186338374_186339089
0.00000
0.036
DataSet_01_19
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AHSG
186337663_186337729_186336300_186336426_186338374_186339089
0.00135
0.013
DataSet_01_19
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Showing 1 to 10 of 181 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9229351_9229411_9229411_9229532_9227155_9227379
0.00219
0.075
DataSet_01_19
View details
ACLY
40052872_40052902_40054001_40054092_40049285_40049427
0.00008
-0.178
DataSet_01_19
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ACSL3
223752547_223752606_223765391_223765498_223725651_223725976
0.00070
-0.092
DataSet_01_19
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AHSG
186336079_186336280_186336285_186336426_186334975_186335139
0.00008
-0.007
DataSet_01_19
View details
AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00025
-0.007
DataSet_01_19
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AHSG
186336079_186336280_186337645_186337863_186334975_186335139
0.00756
-0.111
DataSet_01_19
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ALB
74275071_74275140_74275140_74275204_74274354_74274522
0.00032
-0.072
DataSet_01_19
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ANKRD11
89371613_89371752_89383340_89383486_89357420_89357591
0.00047
0.227
DataSet_01_19
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ANXA6
150519713_150519804_150527444_150527487_150518913_150519008
0.00084
-0.106
DataSet_01_19
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ARIH2
48964894_48965246_48999044_48999112_48960180_48960244
0.00357
-0.073
DataSet_01_19
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Showing 1 to 10 of 73 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AKAP8L
15509440_15510221_15510112_15510221_15508524_15508666
0.00131
0.088
DataSet_01_19
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ENPP3
131995385_131995502_131995385_131995421_131996219_131996329
0.00083
-0.085
DataSet_01_19
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HNRNPH1
179043869_179044111_179044021_179044111_179043126_179043219
0.00373
0.046
DataSet_01_19
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KMT2A
118361910_118362033_118361910_118362024_118362458_118362643
0.00607
0.088
DataSet_01_19
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KREMEN1
29534611_29534821_29534611_29534770_29536269_29536354
0.00988
0.132
DataSet_01_19
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NELFCD
57568678_57568819_57568678_57568730_57569164_57569294
0.00462
-0.058
DataSet_01_19
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PIGA
15349337_15350114_15349995_15350114_15344035_15344168
0.00443
0.442
DataSet_01_19
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SEMA3B
50312442_50312890_50312442_50312484_50312990_50313046
0.00637
-0.191
DataSet_01_19
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SHMT2
57624136_57624362_57624136_57624257_57624585_57624783
0.00241
0.341
DataSet_01_19
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TMEM165
56284102_56284331_56284102_56284152_56290704_56290810
0.00116
0.054
DataSet_01_19
View details
Showing 1 to 10 of 13 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
APOA2
161192707_161192840_161192707_161192784_161193139_161193215
0.00490
-0.011
DataSet_01_19
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APRT
88876830_88877057_88876830_88876964_88877957_88878064
0.00249
0.088
DataSet_01_19
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ATP6V1G2-DDX39B
31508190_31508343_31508190_31508311_31509726_31509925
0.00249
-0.191
DataSet_01_19
View details
AUP1
74754374_74754520_74754374_74754490_74754597_74754717
0.00662
0.02
DataSet_01_19
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BPIFB2
31596346_31596496_31596353_31596496_31595405_31595566
0.00121
-0.037
DataSet_01_19
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CAPRIN2
30872012_30873849_30872012_30872159_30876192_30876248
0.00274
0.341
DataSet_01_19
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CDC27
45229171_45229302_45229171_45229284_45232037_45232152
0.00243
0.097
DataSet_01_19
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CHTF18
840330_840399_840346_840399_840176_840269
0.00096
0.144
DataSet_01_19
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DDX5
62496792_62497000_62496792_62496891_62498127_62498187
0.00000
0.115
DataSet_01_19
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EML4
42553184_42553392_42553293_42553392_42552606_42552694
0.00345
-0.012
DataSet_01_19
View details
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACTB
5567911_5569031_5567911_5568350_5568791_5569031
0.00360
0.009
DataSet_01_19
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AHSA2
61412636_61413632_61412636_61412753_61413580_61413632
0.00532
0.116
DataSet_01_19
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AKR1C2
5041391_5042858_5041391_5041469_5042741_5042858
0.00009
0.078
DataSet_01_19
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ANKZF1
220100731_220101373_220100731_220100817_220101043_220101373
0.00237
-0.03
DataSet_01_19
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APOA2
161193170_161193349_161193170_161193215_161193308_161193349
0.00213
-0.156
DataSet_01_19
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ARAP1
72423482_72424288_72423482_72423613_72424220_72424288
0.00686
-0.095
DataSet_01_19
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ATF4
39916568_39917676_39916568_39916756_39917358_39917676
0.00364
0.046
DataSet_01_19
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CLPP
6361879_6362553_6361879_6361951_6362456_6362553
0.00980
-0.044
DataSet_01_19
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CPSF7
61183137_61183991_61183137_61183256_61183576_61183991
0.00020
0.098
DataSet_01_19
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DCXR
79994066_79994324_79994066_79994184_79994259_79994324
0.00584
0.025
DataSet_01_19
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
36642420
T
C
9.55653E-06
MAP7D1
+
FALSE
chr1
16909220
T
C
0.00029
NBPF1
-
FALSE
chr1
28859264
T
G
0.00030
RCC1
+
FALSE
chr1
53359182
A
G
0.00321
ZYG11A
+
TRUE
AluSx
SINE,Alu
chr1
36068370
T
C
0.00067
PSMB2
-
TRUE
AluSc
SINE,Alu
chr1
16112795
A
G
0.00499
FBLIM1
+
FALSE
chr1
168213516
A
G
0.00233
.
FALSE
AluSx1
SINE,Alu
chr1
51822219
G
A
0.00223
EPS15
-
FALSE
chr1
89447720
G
A
0.00029
KYAT3,RBMXL1
-
FALSE
chr1
20976078
T
C
0.00344
PINK1,PINK1-AS
+,-
FALSE
AluSz
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression