Dataset Overview
RBP
SLTM
Knock-Method
shRNA
RBP Family
RRM_1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR185JGT
Platform
HiSeq
Pubmed ID
32252787
SLTM - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of SLTM
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
9.32
20.75
1.32893
1.71185E-07
6.09512E-06
A1CF
29.34
37.62
0.56170
1.67350E-05
0.00032
AADAC
0.71
2.11
1.66487
1.35896E-05
0.00027
AARS
40.96
55.34
0.54943
2.26478E-05
0.00042
ABCA1
21.74
24.52
0.28137
0.03100
0.12951
ABCA5
6.64
10.49
0.85454
1.15804E-06
3.26261E-05
ABCB1
17.2
34.33
1.03491
1.07219E-14
1.34524E-12
ABCB8
3.89
5.22
0.47954
0.04832
0.17499
ABCC1
23.89
14.5
-0.63388
6.70335E-06
0.00015
ABCC2
78.41
108.91
0.57066
1.29045E-05
0.00026
Showing 1 to 10 of 3,677 entries
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Function Analysis of Target Genes of SLTM
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52622648_52622741_52619601_52619745_52645340_52645387
0.00566
0.047
DataSet_01_192
View details
ABCC2
101576820_101576968_101572774_101572901_101577064_101577241
0.00545
0.136
DataSet_01_192
View details
AC084018.1
122240536_122240593_122239612_122239714_122240784_122240816
0.00999
-0.5
DataSet_01_192
View details
ACSL4
108934231_108934360_108926364_108926781_108939372_108939425
0.00112
-0.263
DataSet_01_192
View details
ACSM2B
20556033_20556144_20554456_20554584_20556478_20556580
0.00138
0.067
DataSet_01_192
View details
AFMID
76201683_76201819_76200908_76200981_76202026_76202131
0.00516
0.289
DataSet_01_192
View details
AHSG
186337645_186337696_186336285_186336426_186338374_186339089
0.00008
-0.055
DataSet_01_192
View details
AHSG
186334972_186335139_186334231_186334316_186338374_186339089
0.00072
0.178
DataSet_01_192
View details
AHSG
186337663_186337729_186336285_186336426_186338374_186339089
0.00366
-0.014
DataSet_01_192
View details
AHSG
186337615_186337729_186336285_186336426_186338374_186339089
0.00575
-0.011
DataSet_01_192
View details
Showing 1 to 10 of 240 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52601621_52601752_52603747_52603882_52595833_52596072
0.00585
-0.13
DataSet_01_192
View details
ACTN4
39200896_39200982_39201915_39202001_39200034_39200116
0.00360
-0.045
DataSet_01_192
View details
AFG3L2
12353003_12353157_12356692_12356830_12351304_12351412
0.00000
-0.54
DataSet_01_192
View details
AFMID
76201520_76201599_76201683_76201819_76200908_76200981
0.00226
-0.159
DataSet_01_192
View details
AFP
74306318_74306530_74309067_74309161_74303890_74304023
0.00312
-0.006
DataSet_01_192
View details
AHSG
186334975_186335139_186336324_186336426_186334231_186334316
0.00000
-0.196
DataSet_01_192
View details
AHSG
186336079_186336280_186336285_186336426_186334975_186335139
0.00006
0.012
DataSet_01_192
View details
AHSG
186336324_186336426_186337645_186337729_186334231_186334316
0.00010
0.011
DataSet_01_192
View details
AHSG
186336079_186336280_186336324_186336426_186334975_186335139
0.00012
0.007
DataSet_01_192
View details
AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00025
0.01
DataSet_01_192
View details
Showing 1 to 10 of 102 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ANKRD10
111536044_111536158_111536076_111536158_111530887_111532459
0.00809
-0.198
DataSet_01_192
View details
BIRC6
32696081_32696219_32696081_32696192_32698179_32698307
0.00843
0.192
DataSet_01_192
View details
BPIFB2
31606510_31606716_31606510_31606628_31606867_31606921
0.00006
0.055
DataSet_01_192
View details
BPIFB2
31602310_31602453_31602310_31602334_31603241_31603302
0.00815
-0.085
DataSet_01_192
View details
CFB
31915732_31915971_31915732_31915858_31916150_31916296
0.00425
0.028
DataSet_01_192
View details
COL27A1
117044736_117044844_117044736_117044764_117045988_117046237
0.00346
-0.044
DataSet_01_192
View details
DLST
75357758_75357896_75357758_75357870_75359536_75359689
0.00665
0.062
DataSet_01_192
View details
FAM149B1
74992696_74992955_74992696_74992921_74994574_74994698
0.00504
0.191
DataSet_01_192
View details
FGFR1
38277050_38277253_38277056_38277253_38275745_38275891
0.00402
-0.412
DataSet_01_192
View details
HNRNPC
21699116_21699231_21699155_21699231_21698477_21698525
0.00015
-0.074
DataSet_01_192
View details
Showing 1 to 10 of 20 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AARS2
44274230_44274288_44274230_44274269_44274659_44274768
0.00549
0.199
DataSet_01_192
View details
AMBP
116838877_116839038_116838877_116839008_116840372_116840752
0.00824
-0.017
DataSet_01_192
View details
AP1G2
24030720_24030888_24030720_24030844_24031170_24031262
0.00136
0.176
DataSet_01_192
View details
APOA2
161193151_161193247_161193151_161193215_161193384_161193418
0.00000
-0.053
DataSet_01_192
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APOB
21265232_21265410_21265232_21265348_21266384_21266423
0.00002
0.025
DataSet_01_192
View details
ARHGAP1
46701754_46701921_46701754_46701832_46702036_46702113
0.00567
-0.049
DataSet_01_192
View details
ARNTL
13399868_13399992_13399883_13399992_13398186_13398275
0.00144
0.178
DataSet_01_192
View details
ATG9A
220075102_220075311_220075102_220075197_220075432_220075545
0.00905
0.047
DataSet_01_192
View details
ATP6V1G2-DDX39B
31508190_31508343_31508190_31508311_31509726_31509925
0.00277
-0.19
DataSet_01_192
View details
AUP1
74754067_74754272_74754067_74754186_74754374_74754490
0.00115
-0.026
DataSet_01_192
View details
Showing 1 to 10 of 43 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCB6
220075102_220075545_220075102_220075197_220075432_220075545
0.00255
0.068
DataSet_01_192
View details
ANKZF1
220098854_220100034_220098854_220099010_220099547_220100034
0.00105
0.121
DataSet_01_192
View details
ATF4
39916568_39917676_39916568_39916756_39917358_39917676
0.00000
0.088
DataSet_01_192
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ATG4B
242590424_242590750_242590424_242590526_242590678_242590750
0.00113
0.014
DataSet_01_192
View details
C17orf76-AS1
16342640_16343567_16342640_16342728_16343498_16343567
0.00359
0.016
DataSet_01_192
View details
CAPRIN2
30872012_30873849_30872012_30872159_30873744_30873849
0.00346
-0.11
DataSet_01_192
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CD46
207940357_207943707_207940357_207940540_207943665_207943707
0.00666
0.116
DataSet_01_192
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CDC16
115037658_115038150_115037658_115037956_115038038_115038150
0.00320
0.215
DataSet_01_192
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CDCA7
174228545_174229717_174228545_174228623_174229522_174229717
0.00331
0.224
DataSet_01_192
View details
CFB
31915721_31916289_31915721_31915858_31916150_31916289
0.00868
0.041
DataSet_01_192
View details
Showing 1 to 10 of 57 entries
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
12628188
T
C
3.43513E-08
DHRS3
-
FALSE
chr1
97543764
C
T
0.00840
DPYD
-
FALSE
chr1
16889864
C
A
6.58858E-05
NBPF1
-
FALSE
chr1
156613401
T
C
5.47226E-05
BCAN
+
FALSE
chr1
145281656
A
T
0.00839
NBPF20,NOTCH2NL
+
FALSE
chr1
43917637
G
A
0.00164
SZT2,HYI
+,-
FALSE
chr1
78414329
G
A
0.00874
FUBP1
-
FALSE
A-rich
SINE,Alu
chr1
15991645
T
C
0.00361
.
FALSE
AluSp
SINE,Alu
chr1
204524555
A
G
1.07581E-05
MDM4
+
TRUE
AluY
SINE,Alu
chr1
214524044
T
C
0.00242
PTPN14
-
TRUE
AluSx
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression