Dataset Overview
RBPPUF60
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR558XNA
PlatformHiSeq
Pubmed ID32252787

PUF60 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PUF60
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PUF60


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr457326873AG0.00034PAICS+TRUEAluSx1SINE,Alu
chr132385070TA0.00593PTP4A2-FALSE
chr2229904354GA0.00072THOC5-FALSE
chr1577403107CA3.43068E-05PEAK1-FALSE
chr324019987AC0.00563NR1D2+FALSE
chr10114209888AG0.00386VTI1A+TRUEAluSx3SINE,Alu
chr111084105TA0.00116TARDBP+FALSE
chr143996594TC0.00836PTPRF+FALSE(CGGCTC)nSINE,Alu
chr127107948GA0.00177ARID1A+FALSE
chr541919747CT0.00814C5orf51+FALSEL2cSINE,Alu
chr1204520455TC0.00478MDM4+FALSEAluJbSINE,Alu
chr2128604232AT0.00652POLR2D-FALSE
chr7100958270TC0.00087LOC101927746,IFT22+,-FALSE
chr921331486TG0.00675KLHL9-FALSE
chr1145500918TC0.00127NBPF20,NBPF10,LIX1L+FALSE
chr1657505656TG0.00107POLR2C+FALSE(GGTGGG)nSINE,Alu
chr1161160460TA0.00298ADAMTS4-FALSE(CA)nSINE,Alu
chr146077268AG0.00012NASP+TRUEAluSc8SINE,Alu
chr11769883TC0.00631PDDC1-TRUEAluYSINE,Alu
chr1911256725TC7.46879E-09SPC24-TRUEAluJr4SINE,Alu
chr193811476GC0.00663.FALSE
chr1051613297AG0.00347TIMM23B,TIMM23+,-FALSE
chr117393261TC3.60266E-05PADI2-FALSE
chr167874859TC0.00374SERBP1-TRUEAluSxSINE,Alu
chr119542464TC0.00736LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr315113655TC0.00025RBSN-TRUEAluSz6SINE,Alu
chr1075009921TC0.00639DNAJC9-AS1,MRPS16+,-FALSEAluYSINE,Alu
chr119934758CG1.75422E-05MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr187379498TG0.00784SEP15-FALSE
chr1148003730TC0.00415NBPF8-TRUEL1MC4SINE,Alu
chr286365817AG0.00046PTCD3+FALSE
chr119542631TC0.00741LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr2176791182TC0.00603LNPK-TRUEMSTDSINE,Alu
chr9115447531TC0.00164INIP-TRUEAluJbSINE,Alu
chr1143398850GT0.00639.FALSE
chr4155457601TC0.00423PLRG1-FALSE
chr1121115958TC0.00818SRGAP2-AS1,SRGAP2D,SRGAP2B,SRGAP2C+,-FALSE
chr124746451AG0.00683NIPAL3+TRUEAluScSINE,Alu
chr192946618AG0.00062GFI1-FALSE
chr633384326AT0.00678.FALSE
chr13110407598AG0.00222IRS2-FALSE
chr1060047609AG0.00979CISD1+FALSE(A)nSINE,Alu
chr154692341TC0.00045SSBP3-FALSE(T)nSINE,Alu
chr1214557685CA0.00205PTPN14-FALSE
chr1320247038AG0.00391MPHOSPH8+TRUEAluJbSINE,Alu
chr657034840TG0.00581ZNF451,LOC101927211+,-FALSE
chr135649803AC0.00659SFPQ-FALSE
chr144088112GT0.00822PTPRF+FALSE(T)nSINE,Alu
chr1590819619AG5.14004E-06.FALSEAluSxSINE,Alu
chr136602202TC0.00122TRAPPC3-FALSE
chr1231154935CT0.00093FAM89A-FALSE
chr127205871GT0.00931.FALSE
chr126755136AG0.00279LIN28A+FALSEAluSx1SINE,Alu
chr1153533813AT0.00451S100A2-FALSE
chr2201774279TC9.55391E-05.FALSEAluSzSINE,Alu
chr2128605225GA0.00401POLR2D-FALSE
chr1109855150AC0.00062SORT1-FALSEA-richSINE,Alu
chr315112630CT0.00017RBSN-FALSEAluSq2SINE,Alu
chr121810693AG0.00370NBPF3+FALSEL1MC4SINE,Alu
chr147746678GC0.00328STIL-FALSE
chr892075904TC0.00242OTUD6B-AS1-FALSELTR67BSINE,Alu
chr11677253TC0.00145SLC35E2-FALSE
chr744839297AT0.00777PPIA+FALSE
chr1179044181AG0.00083FAM20B+TRUEAluSxSINE,Alu
chr1145688664AT0.00087NBPF20,NBPF10,RNF115+FALSE
chr1264842974CA0.00925.FALSEAluSzSINE,Alu
chr1159946750GA0.00105LINC01133+FALSE(GAAA)nSINE,Alu
chr126755175GC0.00211LIN28A+FALSEAluSx1SINE,Alu
chr1114227223GA0.00699MAGI3+FALSE
chr131342374AC0.00446SDC3-FALSE(A)nSINE,Alu
chr1950370106TG0.00359PNKP-FALSE
chr310193511AG0.00116VHL+TRUEAluJrSINE,Alu
chr285773376TC0.00607GGCX-TRUEAluYSINE,Alu
chr3195961254CT0.00119.FALSE
chr133147722GA1.17176E-11SYNC,RBBP4+,-FALSE
chr2127826533AG0.00104BIN1-FALSE
chr168624878CT0.00465GNG12-AS1,WLS+,-FALSE
chr11595006TC0.00156CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr121810022AT0.00218NBPF3+FALSE
chr237328097TC0.00301.FALSE
chr5138618619AG0.00513SNHG4,MATR3+TRUEAluSxSINE,Alu
chr320025661CT4.83976E-05RAB5A,PP2D1+,-FALSE
chr29629304AG0.00121ADAM17-FALSE
chr233046027GC0.00397TTC27+FALSE
chr177123232CG0.00250DLG4,ACADVL+,-FALSE
chr1160967855TC0.00042F11R-TRUEAluSpSINE,Alu
chr4177252238AG9.63526E-05SPCS3+TRUE
chr195363041CT0.00105CNN3-FALSE
chr185787118GC0.00104DDAH1-FALSE
chr167874689TC0.00112SERBP1-TRUEAluSx3SINE,Alu
chr193298756TC0.00264FAM69A,RPL5+,-FALSEMER5CSINE,Alu
chr3100083425GA0.00717TOMM70-FALSEFAMSINE,Alu
chr822995145TC3.53807E-06TNFRSF10D-FALSE
chr116889014CT0.00722NBPF1-FALSE
chr2217366821AG0.00510.FALSEAluSz6SINE,Alu
chr1145511988AG0.00965NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1145284883AG0.00062NBPF20,NOTCH2NL+FALSEL2aSINE,Alu
chr8144827206AT0.00196FAM83H-AS1+FALSEERVL-B4-intSINE,Alu
chr349315588TG0.00182USP4-FALSE
chr579922263TG0.00913DHFR-FALSEHAL1SINE,Alu
chr155319888TG0.00000DHCR24-FALSE
chr1346700519CA0.00089LCP1-FALSE
chr146269493GC0.00233MAST2+FALSE
chr366419942AG0.00284SLC25A26+FALSE
chr110517352TC0.00064.FALSEAluJrSINE,Alu
chr136068237TC0.00054PSMB2-TRUEAluScSINE,Alu
chr5170832637CT0.00071NPM1+FALSE
chr1165370475GC0.00256RXRG-FALSE
chrX2824343TC0.00108ARSD-TRUEAluJbSINE,Alu
chr1911257673TC0.00211SPC24-TRUEAluSpSINE,Alu
chr314986111TC0.00999FGD5-AS1-TRUEFLAM_CSINE,Alu
chr2206987731TC0.00731.FALSEAluJbSINE,Alu
chr2202083872AG0.00022CASP10+TRUEAluSzSINE,Alu
chr11345006AG0.00123.FALSEAluSgSINE,Alu
chr121780000GT0.00153NBPF3+FALSEERVL-E-intSINE,Alu
chr1154321623GA0.00782ATP8B2+FALSE
chr116889620TC0.00884NBPF1-FALSE
chr1274934944AG0.00094ATXN7L3B+FALSE
chr7129251289CT0.00808.FALSE
chr9111781015AC0.00853TMEM245-FALSE
chr1120839682AG0.00073FAM72B+FALSE
chr1145283733AG0.00458NBPF20,NOTCH2NL+FALSE
chr3183976477CT0.00215ECE2+FALSE
chr1180063334GA2.71425E-05CEP350+FALSE
chr1144595935GA0.00636NBPF20+FALSEAluJbSINE,Alu
chr110520202TC0.00529.FALSEAluSxSINE,Alu
chr126449341AG0.00622PDIK1L+FALSE
chr8144357992AG0.00780GLI4+FALSE
chr1490509582TC0.00017TDP1+FALSE
chr5177023119TA0.00295TMED9+FALSE
chr121810575TC0.00827NBPF3+FALSE
chr1179044181AG0.00660FAM20B+TRUEAluSxSINE,Alu
chr194930345GA0.00223ABCD3+FALSE
chr5154194459CA0.00832LARP1+FALSE
chr357612623TC3.38108E-06DENND6A,PDE12+,-FALSE
chr248605828TA0.00650FOXN2+FALSE(T)nSINE,Alu
chr544818826GA0.00595.FALSE
chr1075008846TC0.00135DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr23193040GA0.00650TSSC1-FALSE
chr2133974092GC0.00865C21orf59-FALSE
chr138174665GA0.00339CDCA8+FALSE
chr146076543AG0.00989NASP+TRUEAluSxSINE,Alu
chr1819445881TA0.00224MIB1+FALSE
chr357743246GA0.00221SLMAP+FALSE
chr1946052996TC2.38036E-05OPA3-TRUEAluSz6SINE,Alu
chr642856064AG0.00019RPL7L1+TRUEAluSzSINE,Alu
chr1590820104AG4.84304E-05.FALSEAluYSINE,Alu
chr1765334885TC2.77388E-05PSMD12-TRUEAluSqSINE,Alu
chr3183209036TC1.78981E-05KLHL6-TRUEAluSqSINE,Alu
chr3197611048AG0.00064.FALSEAluSx1SINE,Alu
chr119934900GA0.00605MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr1100550370TA0.00743SASS6-FALSE
chr124288530AT0.00915PNRC2+FALSE
chr127202959TC0.00653.FALSEAluSq2SINE,Alu
chr146075720AG0.00105NASP+TRUEAluSx4SINE,Alu
chr1113455441CA0.00020SLC16A1-FALSE(A)nSINE,Alu
chr1237064432CG0.00019MTR+FALSE
chr13416449CA0.00748MEGF6-FALSE
chr178414334CA0.00702FUBP1-FALSEA-richSINE,Alu
chr1160175191AC0.00509LOC729867,PEA15+,-FALSE(GGC)nSINE,Alu
chr3160213318TG0.00215KPNA4-FALSE
chr198005999TC0.00027TIMM44-FALSE
chr1475202963AG2.20276E-06FCF1+TRUEAluSxSINE,Alu
chr237429626AG0.00028CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr5125961204AG0.00196PHAX+TRUEAluSzSINE,Alu
chr6100005419AG2.18273E-06CCNC-FALSEAluSgSINE,Alu
chr1542503334CT0.00448TMEM87A-FALSE(T)nSINE,Alu
chr71199790GC0.00049ZFAND2A-FALSE
chr1146650289CT0.00736PDIA3P1+FALSE
chr185715978CG0.00815C1orf52-FALSE
chr1145509570AG0.00028NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr189447854GT0.00310KYAT3,RBMXL1-FALSE
chr136534934AG0.00464.FALSEAluJoSINE,Alu
chr116945409TA0.00290CROCCP2-FALSE
chr339453160GA0.00000RPSA+FALSE
chr1100490275AG0.00748SLC35A3+TRUEAluSc5SINE,Alu
chr3113351702AG0.00042.FALSE7SLRNASINE,Alu
chr237328027TC0.00026.FALSE
chr1148251083TC0.00041NBPF8,NBPF14,NBPF9-FALSEL1MC4SINE,Alu
chr744841799AG0.00693PPIA+TRUEAluSxSINE,Alu
chr5130537747AG1.40133E-05LYRM7+TRUEAluJbSINE,Alu
chr2207943813GT0.00619KLF7-FALSE(TTTTGT)nSINE,Alu
chr18045343CA0.00162.FALSE
chr286249906TC0.00352LOC90784-TRUEAluJrSINE,Alu
chr348787118TC0.00359PRKAR2A-TRUEAluSx3SINE,Alu
chr72473761TC0.00126CHST12+FALSE(CCGC)nSINE,Alu
chr11252654AG0.00125CPSF3L-FALSEAluSpSINE,Alu
chrX2825114TC0.00738ARSD-TRUEAluSx1SINE,Alu
chr543575020TC8.37337E-06NNT-AS1-TRUEAluSq2SINE,Alu
chr12125513906CA0.00464.FALSEAluSx1SINE,Alu
chr152306075TC8.71211E-05NRDC-FALSE(TCA)nSINE,Alu
chr110519888TC0.00878.FALSEAluJrSINE,Alu
chr136642420TC0.00162MAP7D1+FALSE
chr1150783955TC0.00077ARNT-FALSE(CA)nSINE,Alu
chr1100440553AG9.79324E-05SLC35A3+TRUEAluJbSINE,Alu
chr170718269AG0.00234.FALSE
chr1205687358TC0.00432NUCKS1-FALSE(T)nSINE,Alu
chr6160100882TC3.93365E-05SOD2-TRUEAluSzSINE,Alu
chr114599TA0.00304WASH7P-FALSE
chr1269237042AG0.00413MDM2+TRUE
chr1946053393TC0.00514OPA3-TRUEAluSx1SINE,Alu

Differential Expression Gene Analysis