Dataset Overview
RBP
PTBP1
Knock-Method
shRNA
RBP Family
RRM_5
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR064DXG
Platform
HiSeq
Pubmed ID
32252787
PTBP1 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of PTBP1
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
40.38
8.21
-2.75945
3.48656E-115
2.49464E-113
A1CF
29.02
23.96
-0.18778
0.00475
0.00769
A2M
2827.98
1151.56
-1.68873
7.20686E-99
3.73403E-97
AACS
17.52
11.37
-1.04373
1.23755E-45
2.10244E-44
AADAT
2.45
7.47
1.10859
3.97116E-16
1.90839E-15
AAGAB
4.83
14.0
1.21959
1.42356E-37
1.85819E-36
AAK1
1.2
5.42
2.29119
2.05189E-56
4.56377E-55
AAMDC
27.35
29.36
-0.29925
0.00983
0.01530
AAMP
124.44
107.24
-0.59037
1.70872E-18
9.47786E-18
AAR2
22.2
16.79
-0.83681
4.78746E-28
4.32759E-27
Showing 1 to 10 of 9,791 entries
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Function Analysis of Target Genes of PTBP1
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52622648_52622741_52619601_52619745_52623792_52623840
0.00077
-0.23
DataSet_01_197
View details
ABCC6
16249648_16249711_16248729_16248888_16251519_16251666
0.00010
-0.158
DataSet_01_197
View details
ABI1
27044583_27044670_27040526_27040712_27047990_27048167
0.00289
-0.143
DataSet_01_197
View details
ABLIM1
116213137_116213242_116211382_116211430_116225456_116225586
0.00026
0.042
DataSet_01_197
View details
ACACA
35567380_35567404_35564570_35564714_35578644_35578763
0.00391
-0.205
DataSet_01_197
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ACAD8
134133229_134133449_134132413_134132516_134134801_134135744
0.00802
-0.101
DataSet_01_197
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ACSL4
108934231_108934360_108926364_108926601_108939372_108939425
0.00381
0.07
DataSet_01_197
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ACSL4
108934231_108934360_108926364_108926604_108939372_108939425
0.00923
0.308
DataSet_01_197
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ADAM9
38928816_38928922_38913095_38913291_38934746_38934930
0.00734
-0.498
DataSet_01_197
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ADD3
111892062_111892158_111890120_111890244_111893083_111893969
0.00999
-0.166
DataSet_01_197
View details
Showing 1 to 10 of 382 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9251202_9251352_9252061_9252080_9248134_9248296
0.00929
0.499
DataSet_01_197
View details
ABCC1
16103632_16103758_16108347_16108485_16101672_16101849
0.00882
0.134
DataSet_01_197
View details
ABCC6
16256849_16257049_16259479_16259635_16255294_16255421
0.00093
-0.304
DataSet_01_197
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ABI1
27044583_27044670_27047990_27048167_27040526_27040712
0.00269
0.127
DataSet_01_197
View details
ABI1
27044583_27044670_27047990_27048164_27040526_27040712
0.00366
0.153
DataSet_01_197
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ACACA
35518694_35518964_35536200_35536347_35512604_35512702
0.00792
0.173
DataSet_01_197
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ACAT2
160188036_160188218_160189542_160189660_160183950_160184085
0.00007
0.139
DataSet_01_197
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ACAT2
160189542_160189660_160196201_160196345_160188036_160188218
0.00048
0.106
DataSet_01_197
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ACIN1
23550956_23551045_23559190_23559310_23548755_23550018
0.00091
-0.113
DataSet_01_197
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ACP1
272036_272150_275139_275201_271865_271939
0.00903
0.192
DataSet_01_197
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Showing 1 to 10 of 149 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AGXT
241815351_241815508_241815351_241815421_241816953_241817049
0.00884
-0.278
DataSet_01_197
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AKR1C2
5041391_5042858_5042741_5042858_5040816_5040939
0.00092
0.087
DataSet_01_197
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ANAPC11
79849607_79849729_79849607_79849709_79851427_79851490
0.00963
0.25
DataSet_01_197
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ANLN
36458928_36459088_36458928_36459076_36459777_36459923
0.00314
0.167
DataSet_01_197
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AP1G2
24033714_24033869_24033770_24033869_24033368_24033597
0.00250
0.06
DataSet_01_197
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APOE
45409052_45409301_45409052_45409098_45409858_45410583
0.00001
0.022
DataSet_01_197
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APOH
64224133_64224278_64224137_64224278_64219815_64219892
0.00477
0.129
DataSet_01_197
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CALD1
134617738_134618828_134617738_134618141_134625842_134625988
0.00528
0.071
DataSet_01_197
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CHST15
125771848_125771996_125771870_125771996_125767185_125769855
0.00932
-0.051
DataSet_01_197
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CRELD1
9984760_9984913_9984760_9984856_9985064_9985199
0.00000
0.775
DataSet_01_197
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Showing 1 to 10 of 33 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52573616_52573822_52573616_52573798_52575765_52576039
0.00887
-0.181
DataSet_01_197
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ABCA7
1059005_1059084_1059021_1059084_1058818_1058939
0.00554
0.059
DataSet_01_197
View details
ABCF1
30545849_30545979_30545852_30545979_30545594_30545690
0.00666
0.129
DataSet_01_197
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AC007319.1
188419002_188419120_188419043_188419120_188412199_188412434
0.00090
-0.18
DataSet_01_197
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AES
3054117_3054262_3054117_3054192_3055661_3056194
0.00371
0.025
DataSet_01_197
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AES
3054117_3054238_3054117_3054192_3055661_3056194
0.00855
0.02
DataSet_01_197
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AMBP
116838877_116839046_116838877_116839008_116840372_116840752
0.00035
-0.098
DataSet_01_197
View details
ANKRD11
89383340_89383486_89383340_89383483_89484691_89484776
0.00041
0.215
DataSet_01_197
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APRT
88876830_88877057_88876830_88876964_88877957_88878064
0.00015
-0.029
DataSet_01_197
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AQP7
33384947_33385288_33384947_33385229_33385646_33385864
0.00380
-0.449
DataSet_01_197
View details
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AKT1
105237081_105238789_105237081_105237184_105238701_105238789
0.00156
-0.031
DataSet_01_197
View details
ANAPC5
121764898_121766300_121764898_121765034_121766118_121766300
0.00637
-0.038
DataSet_01_197
View details
AP1G2
24030720_24031624_24030720_24030844_24031170_24031624
0.00356
-0.114
DataSet_01_197
View details
ARMC10
102724128_102724509_102724128_102724277_102724476_102724509
0.00400
-0.581
DataSet_01_197
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ATF4
39916568_39917676_39916568_39916756_39917358_39917676
0.00806
-0.028
DataSet_01_197
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CAPN2
223957542_223958227_223957542_223957611_223958148_223958227
0.00415
-0.171
DataSet_01_197
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CCNG1
162864576_162864810_162864576_162864670_162864770_162864810
0.00241
0.126
DataSet_01_197
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CERS2
150939867_150940190_150939867_150939960_150940139_150940190
0.00179
-0.024
DataSet_01_197
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CYTH2
48978094_48981402_48978094_48978206_48981325_48981402
0.00102
0.19
DataSet_01_197
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DDX41
176943288_176943836_176943288_176943448_176943725_176943836
0.00364
-0.066
DataSet_01_197
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
245008386
G
C
0.00041
.
FALSE
MER2
SINE,Alu
chr1
10519787
A
T
0.00037
.
FALSE
(A)n
SINE,Alu
chr1
27205214
T
C
0.00799
.
FALSE
AluSc
SINE,Alu
chr1
28836973
A
G
0.00017
SNHG3,RCC1
+
TRUE
AluSc
SINE,Alu
chr1
67874731
T
C
0.00145
SERBP1
-
TRUE
AluSx3
SINE,Alu
chr1
120162635
A
T
0.00203
ZNF697
-
FALSE
chr1
74672474
G
A
0.00014
FPGT-TNNI3K,FPGT
+
FALSE
X12_DNA
SINE,Alu
chr1
36392543
G
T
0.00971
.
FALSE
(T)n
SINE,Alu
chr1
6583701
T
C
0.00029
NOL9
-
FALSE
chr1
55316322
A
G
0.00266
DHCR24
-
FALSE
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression