Dataset Overview
RBP
SF3A3
Knock-Method
shRNA
RBP Family
SF3a60_bindingd
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR374NMJ
Platform
HiSeq
Pubmed ID
32252787
SF3A3 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of SF3A3
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
10.25
19.01
0.89534
2.36256E-12
2.09244E-11
AACS
9.0
7.16
-0.38840
0.00109
0.00247
AADAC
0.25
1.78
2.93245
2.34599E-17
3.86911E-16
AADAT
10.61
7.64
-0.29346
0.03143
0.05140
AAED1
3.77
5.19
0.45151
0.00493
0.00969
AAGAB
9.8
14.68
0.56185
6.18015E-06
2.11375E-05
AAMP
87.51
106.77
0.50920
0.00027
0.00069
AAR2
9.94
24.34
1.30308
1.88595E-29
8.89642E-28
AARS
38.38
51.24
0.41943
0.00042
0.00104
AARS2
5.75
8.38
0.44270
0.00033
0.00083
Showing 1 to 10 of 8,467 entries
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Function Analysis of Target Genes of SF3A3
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9241795_9241869_9232689_9232773_9242497_9242619
0.00000
-0.02
DataSet_01_202
View details
AAGAB
67495885_67495935_67495077_67495236_67496381_67496486
0.00101
-0.499
DataSet_01_202
View details
ABCC2
101601723_101601850_101594136_101594292_101603555_101603657
0.00267
-0.052
DataSet_01_202
View details
ACAT1
108014709_108014774_108013163_108013277_108016928_108017086
0.00556
-0.088
DataSet_01_202
View details
ACAT2
160199201_160199312_160198354_160198488_160199690_160200144
0.00010
-0.026
DataSet_01_202
View details
ACLY
40065241_40065321_40063694_40063825_40065762_40065953
0.00952
-0.512
DataSet_01_202
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ACSL1
185687044_185687140_185686006_185686079_185687775_185687910
0.00864
-0.686
DataSet_01_202
View details
ACSL4
108934231_108934360_108926364_108926601_108939372_108939425
0.00973
0.076
DataSet_01_202
View details
ACSM2B
20586743_20587125_20575990_20576175_20587528_20587608
0.00728
0.057
DataSet_01_202
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ACSM2B
20586743_20586829_20575990_20576175_20587528_20587606
0.00743
0.091
DataSet_01_202
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Showing 1 to 10 of 423 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9232689_9232773_9241795_9241847_9231839_9231927
0.00629
-0.014
DataSet_01_202
View details
A2M
9264754_9264807_9264972_9265132_9262909_9262930
0.00954
0.061
DataSet_01_202
View details
ACLY
40054883_40055038_40057948_40058066_40054053_40054092
0.00000
-0.166
DataSet_01_202
View details
ACLY
40054883_40055038_40057948_40058066_40049285_40049427
0.00090
-0.043
DataSet_01_202
View details
AFMID
76198783_76198832_76201997_76202131_76187050_76187141
0.00246
0.17
DataSet_01_202
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AFMID
76200908_76200981_76201683_76201834_76198783_76198832
0.00758
0.14
DataSet_01_202
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AFP
74303890_74304023_74316331_74316470_74302876_74302928
0.00189
-0.076
DataSet_01_202
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AFP
74313178_74313308_74313330_74313393_74310709_74310839
0.00420
-0.074
DataSet_01_202
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AFP
74313178_74313330_74313330_74313393_74310709_74310839
0.00454
-0.073
DataSet_01_202
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AFP
74306318_74306530_74313178_74313393_74303890_74304023
0.00661
0.058
DataSet_01_202
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Showing 1 to 10 of 243 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ATXN2L
28844759_28844966_28844759_28844829_28845385_28845532
0.00000
0.177
DataSet_01_202
View details
CCNT2
135703670_135704035_135703670_135703716_135705305_135705469
0.00734
0.3
DataSet_01_202
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CMTR1
37446184_37446403_37446184_37446297_37446922_37446971
0.00405
0.091
DataSet_01_202
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COMMD9
36297614_36297790_36297686_36297790_36295772_36296322
0.00138
0.24
DataSet_01_202
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DDX54
113600664_113600850_113600736_113600850_113599725_113599802
0.00765
0.034
DataSet_01_202
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FBXO18
5959552_5959698_5959552_5959639_5960304_5960441
0.00504
0.181
DataSet_01_202
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HNRNPH1
179043899_179044104_179044021_179044104_179043098_179043219
0.00157
-0.099
DataSet_01_202
View details
KIAA0430
15728613_15730199_15729512_15730199_15727473_15727700
0.00043
-0.55
DataSet_01_202
View details
MFF
228193393_228195562_228193393_228193505_228197134_228197304
0.00109
-0.073
DataSet_01_202
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MLLT4
168315323_168315492_168315323_168315418_168315847_168316113
0.00057
0.098
DataSet_01_202
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Showing 1 to 10 of 31 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9232576_9232773_9232576_9232755_9241795_9241847
0.00000
-0.036
DataSet_01_202
View details
A2M
9232689_9232765_9232689_9232755_9241795_9241847
0.00014
-0.034
DataSet_01_202
View details
ACIN1
23532248_23532307_23532248_23532274_23532644_23532815
0.00000
-0.083
DataSet_01_202
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ACIN1
23532137_23532307_23532137_23532246_23532644_23532815
0.00460
-0.104
DataSet_01_202
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ALB
74275039_74275183_74275140_74275183_74274354_74274522
0.00930
0.425
DataSet_01_202
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APOA2
161193056_161193291_161193056_161193215_161193384_161193421
0.00000
0.387
DataSet_01_202
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APRT
88876830_88877057_88876830_88876964_88877957_88878064
0.00490
0.044
DataSet_01_202
View details
ASGR1
7081812_7082218_7081812_7081952_7082508_7082674
0.00000
0.314
DataSet_01_202
View details
ATG4B
242610140_242610197_242610155_242610197_242607954_242608100
0.00068
-0.117
DataSet_01_202
View details
ATP1B1
169096443_169096646_169096461_169096646_169094121_169094277
0.00071
0.046
DataSet_01_202
View details
Showing 1 to 10 of 140 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACADVL
7127131_7127388_7127131_7127194_7127286_7127388
0.00172
0.032
DataSet_01_202
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AFMID
76201576_76201819_76201576_76201599_76201683_76201819
0.00388
0.286
DataSet_01_202
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ANAPC5
121783641_121784808_121783641_121783834_121784698_121784808
0.00003
-0.088
DataSet_01_202
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ARRB2
4620992_4621236_4620992_4621047_4621182_4621236
0.00974
0.083
DataSet_01_202
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BLOC1S2
102045853_102046114_102045853_102045970_102046057_102046114
0.00461
-0.115
DataSet_01_202
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C17orf76-AS1
16342350_16342728_16342350_16342374_16342640_16342728
0.00433
0.019
DataSet_01_202
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CFB
31918062_31918549_31918062_31918180_31918395_31918549
0.00289
0.025
DataSet_01_202
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CHKB
51018618_51018845_51018618_51018700_51018786_51018845
0.00311
0.186
DataSet_01_202
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COX4I1
85839338_85840574_85839338_85839470_85840365_85840574
0.00000
-0.064
DataSet_01_202
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CPSF1
145625559_145625887_145625559_145625623_145625747_145625887
0.00438
-0.194
DataSet_01_202
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
19934879
T
C
0.00454
MINOS1,MINOS1-NBL1,RPS14P3
+
FALSE
chr1
35658260
C
G
0.00477
SFPQ
-
FALSE
chr1
111682307
G
C
0.00637
DRAM2,CEPT1
+,-
FALSE
chr1
53684924
A
G
0.00913
C1orf123
-
FALSE
L1MA5A
SINE,Alu
chr1
45279903
C
T
0.00052
.
FALSE
(TCTT)n
SINE,Alu
chr1
53288897
A
G
0.00160
ZYG11B
+
TRUE
AluJo
SINE,Alu
chr1
1717439
T
A
0.00663
GNB1
-
FALSE
chr1
45976112
A
G
1.14998E-06
MMACHC
+
TRUE
AluJr
SINE,Alu
chr1
94032944
C
T
0.00147
BCAR3
-
FALSE
chr1
28865502
G
A
0.00073
RCC1
+
FALSE
Showing 1 to 10 of 391 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression