Dataset Overview
RBPZC3H8
Knock-MethodshRNA
RBP Familyzf-CCCH
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR448JAM
PlatformHiSeq
Pubmed ID32252787

ZC3H8 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of ZC3H8
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of ZC3H8


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr5156904831TC0.00351ADAM19-TRUEMER92BSINE,Alu
chr3196660344TA0.00022SENP5+FALSE
chr3127790249AG0.00057RUVBL1,SEC61A1+,-FALSE
chr131351513GA0.00265SDC3-FALSE
chr239009427AG0.00673.FALSEAluSx3SINE,Alu
chr115832543TC0.00553CASP9-FALSE
chr136068370TC3.60077E-09PSMB2-TRUEAluScSINE,Alu
chr1756049824TC5.91767E-06VEZF1-TRUE
chr1089004545TC0.00057NUTM2A-AS1-FALSEMSTASINE,Alu
chr1089005496TG0.00138NUTM2A-AS1-FALSEMSTB1SINE,Alu
chr146075724AG1.14407E-05NASP+TRUEAluSx4SINE,Alu
chr3195962244GT0.00083.FALSE
chr273339708GA0.00991RAB11FIP5-FALSE
chr1100655177GA0.00923DBT-FALSE
chr29629953CA0.00105ADAM17-FALSE
chr238971059AC0.00539SRSF7-FALSE
chr2242291743AG0.00731SEPT2+FALSE
chr158971831GA0.00801OMA1-FALSE
chr116912138AG0.00197NBPF1-FALSE
chr4184238324GA0.00870WWC2+FALSE
chr121611798CT0.00338LINC00942+FALSE
chr1615794023AG4.91052E-06NDE1+TRUEAluSz6SINE,Alu
chr120976163CT1.02809E-07PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr224227357AG0.00295.FALSEAluScSINE,Alu
chr1331033317CT0.00254HMGB1-FALSE
chr7152551581TA0.00313ACTR3B+FALSE
chr131342374AC0.00446SDC3-FALSE(A)nSINE,Alu
chr2128064446GT0.00652MAP3K2-FALSE(GT)nSINE,Alu
chr19162247TC0.00549.FALSEAluSxSINE,Alu
chr2113289701TG0.00994TTL+FALSE
chr110517613TC0.00375.FALSEAluSx1SINE,Alu
chr1231398555AG0.00401GNPAT+FALSE
chr1919792444AG0.00686ZNF101+TRUEAluJbSINE,Alu
chr5112350098CT7.36383E-05DCP2+FALSE
chr122419433TG0.00156CDC42+FALSE
chr16582161TC0.00697NOL9-TRUEAluSq4SINE,Alu
chr1215035081TC0.00951MGP-FALSE
chr1168220341AG0.00179.FALSEAluSz6SINE,Alu
chr192975244TA0.00220EVI5-FALSE
chr744917281TC0.00222PURB-TRUEAluSzSINE,Alu
chr162627128AG0.00087PATJ+TRUEAluSxSINE,Alu
chrX133930368TG0.00126FAM122B-FALSEG-richSINE,Alu
chr42516790GT0.00141RNF4+FALSE
chr5125961463AG0.00323PHAX+TRUEAluSz6SINE,Alu
chr1179813613TC0.00595TOR1AIP2-FALSE
chr1061548852GA0.00693CCDC6-FALSE
chr11421186CT0.00834ATAD3B+FALSE
chr116890130AC0.00753NBPF1-FALSE
chr11593060TC5.25946E-05CDK11B,SLC35E2B-FALSE
chr125168124GC0.00669CLIC4+FALSE
chr119543465TC0.00427LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr119670860AG0.00419CAPZB-FALSE
chr125894468CG0.00265LDLRAP1+FALSEMIRbSINE,Alu
chr1193058937CT0.00652TROVE2+FALSEAluScSINE,Alu
chr3141879040TC0.00101GK5-TRUEFLAM_CSINE,Alu
chr5179041779CT0.00430HNRNPH1-FALSE
chr1179326847AG0.00031SOAT1+TRUEAluJoSINE,Alu
chr122418122TC0.00790CDC42+FALSE
chr1205583610TC0.00501ELK4-FALSE
chr1119574537GA0.00935WARS2-FALSE
chr12125114CT8.70493E-12FAAP20-FALSE
chr315113799TC0.00200RBSN-TRUEAluSz6SINE,Alu
chr1610623577TC0.00408EMP2-TRUEAluSpSINE,Alu
chr1193466866GT0.00559MIR1304-FALSEAluJrSINE,Alu
chr1569991TG0.00980.FALSE
chr136068052GT1.69686E-12PSMB2-FALSEL1ME4bSINE,Alu
chr1939433141AG0.00224FBXO17-FALSEAluJbSINE,Alu
chr116953672CT0.00243CROCCP2-FALSE
chr729961659CG7.23387E-07SCRN1-FALSE
chr6166824702CT0.00587RPS6KA2-FALSE(T)nSINE,Alu
chr535058802TC0.00152PRLR-FALSE
chr46925237CG0.00870TBC1D14+FALSE
chr131732602CA0.00336SNRNP40-FALSE
chr136690599AG0.00406THRAP3+FALSE
chr1179084080TG0.00926ABL2-FALSE
chr21652354GA0.00000PXDN-FALSE
chr1145324364CG0.00157NBPF20,NBPF10+FALSE
chr1421928940TC0.00212RAB2B-TRUEAluSpSINE,Alu
chr634231301GC0.00772.FALSE
chr19162932AT0.00635.FALSE
chr197144546AC0.00803.FALSE
chr146093409AC0.00383GPBP1L1-FALSEA-richSINE,Alu
chr125570692CT0.00095RSRP1-FALSE
chr1212911836TC0.00675NSL1-FALSE
chr128865502GA0.00073RCC1+FALSE
chr1254526562AT0.00119LOC400043+FALSEL2aSINE,Alu
chr315838717AC0.00673ANKRD28-FALSE(A)nSINE,Alu
chr1958356478AG0.00030ZNF587B+TRUEAluSxSINE,Alu
chr1100657416CT0.00228DBT-FALSEAluJbSINE,Alu
chr116933650AG0.00258NBPF1-FALSEGA-richSINE,Alu
chr3184429155AT0.00056MAGEF1-FALSE
chr1145375858TC0.00069NBPF20,NBPF10+FALSE
chr145976722GT0.00292MMACHC,PRDX1+,-FALSE
chr120826781CT1.74444E-05MUL1-FALSE
chr128825427AG0.00484PHACTR4+TRUEAluSgSINE,Alu
chr136806071GA0.00126STK40-FALSE
chr115989141CG0.00364.FALSE
chr3105295461GA9.74520E-12ALCAM+FALSE
chr11653046TA0.00686CDK11B,CDK11A-FALSE
chr1298942886AG1.80851E-07TMPO+TRUEAluScSINE,Alu
chr145975279TC0.00019MMACHC+FALSEAluSg7SINE,Alu
chr116112795AG4.56234E-06FBLIM1+FALSE
chr123833607AT0.00831E2F2-FALSE
chr1223178477CT0.00519DISP1+FALSE
chr2128064448GT0.00637MAP3K2-FALSE(GT)nSINE,Alu
chr1154554945AG0.00877ADAR-FALSE
chr128662213AG0.00013MED18+TRUEAluSq2SINE,Alu
chr125894462AG0.00101LDLRAP1+FALSEMIRbSINE,Alu
chr237328034TC0.00035.FALSE
chr1566933AG3.50078E-05.FALSE
chr128661665AG0.00808MED18+TRUEAluSgSINE,Alu
chr1332973012AC0.00231BRCA2+FALSE
chr1569803GA0.00166.FALSE
chr153289892AG0.00070ZYG11B+TRUEFRAMSINE,Alu
chr9125887703AC0.00067STRBP-FALSE
chr1474524944TC0.00567BBOF1,ALDH6A1+,-FALSEAluSc8SINE,Alu
chr1220323448CT0.00986RAB3GAP2-FALSE
chr178286136TA0.00706RPL26-FALSE
chr1256345408TG0.00885DGKA+FALSE
chr9131872862CG0.00131CRAT-FALSE
chr1749042242TC0.00054SPAG9-TRUEAluJbSINE,Alu
chr540826639AG0.00978LOC100506548-FALSELTR78SINE,Alu
chr1552202957GT0.00094TMOD3+FALSE(T)nSINE,Alu
chr11125526125AG0.00374CHEK1+TRUEFRAMSINE,Alu
chr1148556784GA0.00100.FALSE
chr1145273345TC0.00190NBPF20,NOTCH2NL+FALSE
chr1144852203TG0.00518NBPF20,PDE4DIP+,-FALSE
chr12113565TG0.00429PRKCZ+FALSE
chr1160062340GA0.00967IGSF8-FALSE
chr126449327AG0.00330PDIK1L+FALSE
chr2101623611AC0.00826RPL31+FALSE
chr1590820171AG0.00185.FALSE
chr5175811091GA0.00592NOP16-FALSE
chr133150643GA0.00606SYNC,RBBP4+,-FALSEAluJoSINE,Alu
chr1172580637TC1.47330E-06SUCO+FALSE
chr194351062TA0.00189GCLM-FALSE
chr12123253723AG0.00371DENR+TRUE(AT)nSINE,Alu
chr1114443475AG0.00538AP4B1-AS1,AP4B1+,-FALSEAluSpSINE,Alu
chr16282426TC0.00043ICMT-TRUEAluSzSINE,Alu
chr110521170TC0.00104DFFA-TRUEAluYSINE,Alu
chr631324110GA0.00521.FALSE
chr128834154GT0.00012SNHG3,RCC1+FALSEAluSgSINE,Alu
chr375779644CA0.00177ZNF717-FALSE
chr1206635244TA0.00195SRGAP2+FALSE
chr35026729CT0.00539BHLHE40+FALSE
chr2203922075AG0.00058NBEAL1+FALSE
chr1424760808CT0.00203DHRS1-FALSE
chr717384395AG1.20082E-06AHR+TRUEAluSxSINE,Alu
chr1572635903CT0.00334HEXA-FALSE
chr11255401GT0.00216CPSF3L-FALSE(GCAGG)nSINE,Alu
chr315113736TC0.00081RBSN-TRUEAluSz6SINE,Alu
chr116889502TC0.00178NBPF1-TRUEL1MC4SINE,Alu
chr1953155625TC0.00074ZNF83-TRUEAluSgSINE,Alu
chr128826128AG0.00060PHACTR4+TRUEAluJbSINE,Alu
chr189887603CT0.00308GBP1P1+FALSE
chr11252248AG0.00938CPSF3L-FALSEAluSxSINE,Alu
chr1269237057AG0.00259MDM2+TRUE
chr187213174TG0.00081SH3GLB1+FALSE
chr765619292AG0.00189CRCP+TRUEAluSz6SINE,Alu
chr1212114663GA0.00858INTS7-FALSE
chr2132481526CA0.00040C2orf27A+FALSE
chr2140195059AG0.00817ETS2+FALSE
chr1145369709AG0.00073NBPF20,NBPF10+TRUEL1MC4SINE,Alu
chr38922054TC0.00300RAD18-FALSE
chr2217366821AG0.00510.FALSEAluSz6SINE,Alu
chr1298943187AG2.29648E-09TMPO+TRUEAluSzSINE,Alu
chr349460407CT0.00080NICN1-FALSEL2cSINE,Alu
chr1615198598CT0.00494PDXDC1,PKD1P6-NPIPP1,LOC100505915+,-FALSE
chr153291425AG2.55913E-05ZYG11B+TRUEAluJrSINE,Alu
chr299812843AG0.00966MRPL30+TRUEAluJbSINE,Alu
chr1121133770AG0.00295SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr211781593GT0.00551GREB1+FALSE
chr131344952CT0.00842SDC3-FALSE
chr133148736AG0.00849SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr153712215GT0.00458LRP8-FALSE
chr5122165501AT0.00051SNX2+FALSE(AC)nSINE,Alu
chr1051612914TC0.00063TIMM23B,TIMM23+,-FALSE
chr18045343CA0.00162.FALSE
chr110521200TC3.54723E-07DFFA-TRUEAluYSINE,Alu
chr540832549CT2.26031E-05RPL37-FALSE
chr4113152490GA0.00221.FALSE
chr1145689533AG0.00051NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr274442407AG0.00384MTHFD2+FALSE
chr457326186AG0.00203PAICS+TRUEAluJrSINE,Alu
chr1942376872AG0.00647.FALSEAluSpSINE,Alu
chr1200375837TG0.00429ZNF281-FALSE(T)nSINE,Alu
chr167874859TC1.49998E-05SERBP1-TRUEAluSxSINE,Alu
chr4170643772CT0.00926CLCN3+FALSE
chr1539887848GA0.00664THBS1+FALSE
chr1953999034AG0.00282.FALSEAluSq2SINE,Alu
chr1326539AG0.00719.FALSE
chr186986259GA5.32960E-05LAMA1-FALSE
chr119542401TC0.00010LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr111347155CT0.00366UBIAD1+FALSE
chr45710647AG5.78692E-06EVC2-FALSE
chr12125511404AG0.00201THRIL-FALSEAluSx1SINE,Alu
chr7138764145TC0.00399ZC3HAV1-FALSE
chr1182686151TC0.00404RAB30-FALSE
chr125655853AG0.00147RSRP1,RHD+,-FALSEAluSzSINE,Alu
chr146075168CA0.00155NASP+FALSEA-richSINE,Alu
chr1201846626CA0.00429IPO9+FALSE(CA)nSINE,Alu
chrX77084038TC0.00265MAGT1-TRUEAluSzSINE,Alu
chr3121382204CT0.00309GOLGB1-FALSE
chr152817434TC0.00799CC2D1B-TRUEAluSg4SINE,Alu
chr2201774341TC0.00073.FALSEAluSzSINE,Alu
chr315114385TC0.00146RBSN-TRUEAluYSINE,Alu
chr825272364CG0.00693DOCK5+FALSE
chr19163465TC0.00342.FALSEAluSpSINE,Alu
chr1205115428CT4.25965E-05DSTYK-FALSE
chr12125511958AG0.00494THRIL-FALSEAluSx1SINE,Alu
chr1109746601AG0.00024KIAA1324+TRUEAluJbSINE,Alu
chr1420940606GA0.00710PNP+FALSE
chr236776053TC0.00029CRIM1+FALSE
chr136068325TC0.00049PSMB2-TRUEAluScSINE,Alu
chr1680636808CT0.00881CDYL2-FALSE
chr16583457TC0.00233NOL9-TRUEAluSqSINE,Alu
chr1945406538CG0.00119TOMM40+FALSE
chr1154554965GA0.00019ADAR-FALSE
chr19163334TC0.00108.FALSEAluSpSINE,Alu
chr123408939TA1.04314E-06KDM1A+FALSE
chr315113810TC0.00201RBSN-TRUEAluSz6SINE,Alu
chr1475202704AG2.33511E-06FCF1+TRUEAluScSINE,Alu
chr3189675266GT0.00781P3H2-FALSE(TG)nSINE,Alu
chr23502198TA0.00764ADI1-FALSE
chr286365817AG0.00046PTCD3+FALSE
chr827661063TA0.00138ESCO2+FALSE(AC)nSINE,Alu
chr348787674TC0.00240PRKAR2A-TRUEAluSpSINE,Alu
chr110517313TC0.00305.FALSEAluJrSINE,Alu
chr256150864CT0.00615EFEMP1-FALSE
chr153288862AG0.00799ZYG11B+TRUEAluJoSINE,Alu
chr185785548CT0.00220DDAH1-FALSE
chr237329352TC0.00403.FALSEAluJr4SINE,Alu
chr123835919CT0.00872E2F2-FALSE
chr151873951GA1.40484E-05EPS15-FALSE
chr315114318TC0.00067RBSN-TRUEAluYSINE,Alu
chr182804129GA0.00157SMCHD1+FALSE
chr1900505GC0.00388KLHL17+FALSE
chr632789807CT0.00281.FALSE
chr1946052996TC2.38036E-05OPA3-TRUEAluSz6SINE,Alu
chr117298138AT0.00465CROCC+FALSE
chr1110136321TA0.00721GNAI3+FALSE
chr636894337GA0.00607C6orf89+FALSEGA-richSINE,Alu
chr19160982TC0.00350.FALSEAluJbSINE,Alu
chr1474524774TC0.00906BBOF1,ALDH6A1+,-FALSEAluSc8SINE,Alu
chrX123046779AG0.00629XIAP+TRUEAluSzSINE,Alu
chrX3523058AC0.00019PRKX-FALSE(AC)nSINE,Alu
chr127205634TC0.00025.FALSEFLAM_ASINE,Alu
chr6150047430TC0.00107NUP43-TRUEAluScSINE,Alu
chr269330284GA0.00373ANTXR1+FALSEMER91ASINE,Alu
chr1226352498TG0.00636ACBD3-FALSE
chr237331065TC0.00585.FALSEAluSx1SINE,Alu
chr1495555551CT0.00404DICER1-FALSE
chr264687777GT7.38315E-07LGALSL+FALSE
chr3137787047CT0.00735DZIP1L-FALSE
chr122400707CG0.00158CDC42+FALSEAluSc8SINE,Alu
chr2128602974AT4.23982E-05.FALSEAluSpSINE,Alu
chrX77083955TC0.00065MAGT1-TRUEAluSzSINE,Alu
chr1450053348GA0.00067.FALSE7SLRNASINE,Alu
chr2100897573GA0.00231LONRF2-FALSE
chrX37699364CG0.00695DYNLT3-FALSE
chr4113346996GA0.00191ALPK1+FALSE
chr9136897584CA0.00060BRD3-FALSEA-richSINE,Alu
chr1179832748GC7.50400E-12TOR1AIP2-FALSEFLAM_CSINE,Alu
chr268402796CT0.00656PNO1+FALSE
chr3181430508GA3.55222E-06SOX2-OT,SOX2+FALSE
chr136770621GT0.00424THRAP3+FALSE(T)nSINE,Alu
chr136787880CT0.00023EVA1B-FALSE
chr261705068AT0.00103.FALSE
chr119586520AG0.00305MRTO4+TRUEAluSzSINE,Alu
chr2218572729AG0.00228PEX26+TRUEAluYf1SINE,Alu
chr119542310TC0.00873LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1194903795GT0.00328SESN3-FALSE
chr1779838088TC6.81311E-05.FALSEAluSxSINE,Alu
chr16682037GA0.00302PHF13+FALSE
chr133148282AG0.00825SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr6158613393AT0.00108GTF2H5+FALSE
chr179003523CG0.00036PTGFR+FALSE
chr2172412829TA0.00477CYBRD1+FALSE
chr116935130CT0.00155NBPF1-FALSE
chr161411036AG0.00766GNPTG+TRUEAluSzSINE,Alu
chr314986111TC0.00224FGD5-AS1-TRUEFLAM_CSINE,Alu
chr75410425GC0.00043TNRC18-FALSE(CACCGC)nSINE,Alu
chr1773885248TC0.00017TRIM65-TRUEAluSgSINE,Alu
chr194423353GA0.00057CHAF1A+FALSEGA-richSINE,Alu
chr14105270478GT0.00252ZBTB42+FALSE
chr2174090635TA0.00138ZAK,MLK7-AS1+,-FALSE
chr570248478GA0.00229SMN1,SMN2+FALSEL1MC5aSINE,Alu
chr2206981835TC0.00047.FALSEAluJbSINE,Alu
chr16697343CT0.00054DNAJC11-FALSE
chr5139931626TG0.00490SRA1-FALSE
chr348787052TC0.00226PRKAR2A-TRUEAluSx3SINE,Alu
chr3179115635TC0.00453GNB4-TRUEAluSg7SINE,Alu
chr841401497AG0.00051LOC102723729,GINS4+,-FALSEAluSq2SINE,Alu
chr125893928TA0.00388LDLRAP1+FALSE
chr140539213AG0.00693PPT1-FALSE
chr1760522243CG0.00327METTL2A+FALSE

Differential Expression Gene Analysis