Dataset Overview
RBPPKM
Knock-MethodshRNA
RBP FamilyNon-canonical_RBP
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR656DQV
PlatformHiSeq
Pubmed ID32252787

PKM - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PKM
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PKM


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr2062598815CT0.00711ZNF512B-FALSE
chr634213986TA0.00262HMGA1+FALSE
chr5256514GC0.00198SDHA+FALSE
chr121779925TG0.00860NBPF3+FALSEERVL-E-intSINE,Alu
chr2202029997AG0.00335CFLAR+FALSE(TTA)nSINE,Alu
chr120826781CT1.74444E-05MUL1-FALSE
chr11337737GC2.51903E-05MRPL20-FALSE
chr12125627187CT0.00055AACS+FALSE
chr186049364AG0.00207CYR61+FALSE
chr7152342999TC0.00313.FALSEFRAMSINE,Alu
chr119234103GA0.00014IFFO2-FALSE
chr101086801GC0.00421IDI2-AS1,IDI1+,-FALSE
chr810689212CT3.39921E-05PINX1-FALSE
chr1269158881AG0.00219SLC35E3+TRUEAluSpSINE,Alu
chr116933629AG0.00310NBPF1-FALSEGA-richSINE,Alu
chr192862337AG0.00595.FALSEAluSpSINE,Alu
chr1176132119GC0.00134RFWD2-FALSEL3bSINE,Alu
chr5125961573AG0.00217PHAX+TRUEAluSz6SINE,Alu
chr1911257644TC0.00991SPC24-TRUEAluSpSINE,Alu
chr11344998AG0.00062.FALSEAluSgSINE,Alu
chr19162933CT0.00088.FALSE
chr1474524774TC0.00906BBOF1,ALDH6A1+,-FALSEAluSc8SINE,Alu
chr1100658578GA0.00030DBT-FALSE
chr1142660333GA8.80387E-05.FALSE
chr1117910682GA0.00013MAN1A2+FALSE
chr2216903544TC0.00929PECR-TRUEAluSx3SINE,Alu
chr577655392TC0.00080SCAMP1-AS1-TRUEAluSx4SINE,Alu
chr1145512074AG0.00014NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr2171699153CG0.00247GAD1+FALSE
chr2181737842CT0.00350SCHLAP1+FALSE
chr5118174735TC0.00139DTWD2-TRUEAluYSINE,Alu
chr210586899GA0.00312ODC1,SNORA80B-FALSE
chr2103332887TA0.00515MFSD9-FALSEL2d2SINE,Alu
chr195658358TC0.00633TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr425253995CT9.95051E-10PI4K2B+FALSE
chr199673113TC0.00330.FALSEAluSx3SINE,Alu
chr4178281754GA0.00057NEIL3+FALSE
chr1179044309AG0.00558FAM20B+TRUEAluSxSINE,Alu
chr170610735TC0.00259LRRC40-FALSE
chr148764419CT0.00478SPATA6-FALSE
chr41305799CT0.00730MAEA+FALSE
chr1109474776AG0.00149GPSM2,CLCC1+,-FALSEAluSzSINE,Alu
chr1167511256TC0.00838CREG1-FALSE
chr1197128726GA2.50329E-05ZBTB41-FALSE
chr228636644AG0.00269FOSL2+FALSE
chr1203766872GA1.42518E-06ZC3H11A,ZBED6+FALSE
chr126449336AG0.00343PDIK1L+FALSE
chr830535980TC0.00038GSR-TRUEAluJrSINE,Alu
chr136770602TG0.00441THRAP3+FALSE(T)nSINE,Alu
chr1114515717GA0.00018HIPK1+FALSE
chr111783902AG0.00336.FALSEAluSqSINE,Alu
chr1765334766TC4.45484E-05PSMD12-TRUEAluSqSINE,Alu
chr2218571457AG0.00025PEX26+TRUEAluSzSINE,Alu
chr1151027536GC0.00518CDC42SE1-FALSE
chr229023124GT0.00477PPP1CB+FALSE
chr9140709880CT0.00178EHMT1+FALSE
chr179109331GT0.00379IFI44L+FALSELTR26SINE,Alu
chr45743512TC0.00210EVC+FALSE
chr140213628AG0.00058PPIE+TRUEFRAMSINE,Alu
chr2191555984TA0.00171NAB1+FALSE
chr126158906CA0.00362MTFR1L,AUNIP+,-FALSE
chr642857111AG0.00681RPL7L1+FALSEAluSpSINE,Alu
chr42951804AG7.08227E-08NOP14-AS1,NOP14+,-FALSE
chr136068364TC0.00195PSMB2-TRUEAluScSINE,Alu
chr153250625TC0.00178ZYG11B+FALSE
chr1919791274AG7.64703E-05ZNF101+TRUEAluSq2SINE,Alu
chr1156692049AT6.25184E-05ISG20L2-FALSE
chr128566320TC0.00309.FALSEAluSx1SINE,Alu
chr1675479467TC0.00160TMEM170A-TRUEAluJbSINE,Alu
chr1179044100AG0.00081FAM20B+TRUEAluSxSINE,Alu
chr1224575827TC0.00214WDR26-FALSE
chr581571875AT0.00072RPS23-FALSE
chr287821033CA0.00474.FALSE
chr142881767GC0.00437RIMKLA+FALSE
chr1113213004GT0.00206CAPZA1+FALSE
chr5139931632CG0.00052SRA1-FALSE
chr1179325847AG7.26692E-05SOAT1+TRUEAluJoSINE,Alu
chr1160967856TC0.00116F11R-TRUEAluSpSINE,Alu
chr642855057AG0.00034RPL7L1+TRUEAluSpSINE,Alu
chr1767539228GC0.00200.FALSE
chr152381348TG0.00500RAB3B-FALSE
chr237327590TC0.00364.FALSE
chr11597423CT1.10134E-13CDK11B,SLC35E2B-FALSE
chr1755752444CT0.00000MSI2+FALSE
chr123519504TA3.21384E-05HTR1D-FALSE
chr1552840681CT0.00789ARPP19-FALSEAluSx1SINE,Alu
chr633281842GT0.00514.FALSE
chr1931807GA0.00578.FALSE
chr11421531CA0.00467ATAD3B+FALSE
chr5179157298TG0.00816CANX+FALSE
chr1453242354TC3.85910E-06GNPNAT1-TRUEAluJoSINE,Alu
chr132697071CA0.00134EIF3I+FALSEAluSpSINE,Alu
chr373115126AT0.00228PPP4R2+FALSE
chr2191556849AT0.00158NAB1+FALSE
chr110519946TC0.00401.FALSEAluJrSINE,Alu
chr128661692AG0.00219MED18+TRUEAluSgSINE,Alu
chr315113519CT0.00108RBSN-FALSE
chr1144931330CT0.00066NBPF20,PDE4DIP+,-FALSE
chr5118173627TC0.00075DTWD2-TRUE
chr19331101AG0.00072H6PD+FALSEAluSxSINE,Alu
chr132827843GC0.00275FAM229A-FALSE
chr178445292AG7.48186E-07DNAJB4+FALSE
chr1688785189TC0.00636PIEZO1-TRUEAluJrSINE,Alu
chr119234174AG0.00046IFFO2-FALSE
chr348787011TC0.00040PRKAR2A-TRUEAluSx3SINE,Alu
chr791742142CA0.00478CYP51A1-FALSEAluSx3SINE,Alu
chr111783889AG0.00746.FALSEAluSqSINE,Alu
chr1212459257AG0.00068PPP2R5A+FALSE
chr2114356336CT0.00680WASH2P+FALSE
chr145975670AG0.00530MMACHC+TRUEAluSx4SINE,Alu
chr16932082TA0.00330CAMTA1+FALSE
chr115992470GA0.00605.FALSE
chr12120898697AG0.00488GATC+TRUEAluYSINE,Alu
chr1205687213TA0.00950NUCKS1-FALSE
chr1145281408CT0.00220NBPF20,NOTCH2NL+FALSE
chr1204525672AG0.00375MDM4+TRUEAluSzSINE,Alu
chr111298093CT1.54321E-14MTOR-FALSE
chr6114182271GA0.00011MARCKS+FALSE
chr2134728215AG0.00153IFNAR1+TRUEAluScSINE,Alu
chr1205686520AG0.00980NUCKS1-FALSE
chr116133912TC0.00126UQCRHL-TRUE
chr3184766301TC0.00648VPS8+FALSE
chr132739982GA0.00300LCK+FALSE
chr177760704AG0.00297NAA38-FALSE
chr3196555443CA3.82991E-09PAK2+FALSE
chr1738438362GA0.00016WIPF2+FALSEA-richSINE,Alu
chr5159492107AT0.00332TTC1+FALSE
chr1860998527CG0.00078KDSR-FALSE(AGAGAGAC)nSINE,Alu
chr122400702TC0.00883CDC42+FALSEAluSc8SINE,Alu
chr11152601AG0.00075SDF4-FALSE
chr1623478710CA0.00335GGA2-FALSE(AC)nSINE,Alu
chr1942375586AG0.00404.FALSEAluSxSINE,Alu
chr116945227GT0.00090CROCCP2-FALSE
chr1113672616AG0.00940.FALSEAluJbSINE,Alu
chr16160958AG0.00967KCNAB2+FALSE
chr1225357680TC0.00861ETFRF1+FALSE
chr16659505GA0.00196KLHL21-FALSE
chr110518591AT0.00811.FALSE
chr143748051AG0.00489C1orf210-FALSEL2cSINE,Alu
chr9132266648AG0.00230LINC00963+TRUEAluSxSINE,Alu
chr8146016990CT0.00027RPL8-FALSE
chr116841561GA0.00025.FALSE
chr2217366919AG0.00197.FALSEAluSz6SINE,Alu
chr147184569GC0.00061EFCAB14-FALSE
chr128608338AG0.00341SESN2+FALSE
chr1227953266GT0.00198KLHL42+FALSE
chr1120839682AG0.00764FAM72B+FALSE
chr1241795525AG0.00165OPN3,CHML-FALSETHE1BSINE,Alu
chr116933753GA0.00740NBPF1-FALSEGA-richSINE,Alu
chr116891365GA0.00475NBPF1-FALSE
chr3155658362CT0.00807.FALSEMIR3SINE,Alu
chr119586458AG7.27253E-05MRTO4+TRUEAluSzSINE,Alu
chr287002706GA0.00178RMND5A+FALSE
chr116932536CT0.00114NBPF1-FALSEL1MC2SINE,Alu
chr381698130TC2.93981E-08GBE1-FALSE
chr16583270CG0.00026NOL9-FALSE
chr1117117182CT0.00270IGSF3-FALSE
chr12133298428AG7.41792E-11PGAM5+TRUEAluSpSINE,Alu
chr136770600GT0.00792THRAP3+FALSE(T)nSINE,Alu
chr1230975454AG0.00438C1orf198-FALSE
chr1179042701AG0.00132FAM20B+TRUEAluSx1SINE,Alu
chr110518921CT0.00398.FALSEAluSx3SINE,Alu
chr171531596AG1.07667E-05ZRANB2-AS1,ZRANB2+,-FALSE
chr2242164677AG0.00117ANO7+TRUEAluSgSINE,Alu
chr144685732TC9.79150E-12DMAP1+FALSE
chr128825465AG0.00756PHACTR4+TRUEAluSgSINE,Alu
chr1179832838AG0.00018TOR1AIP2-FALSEMLT1LSINE,Alu
chr1028971535TA0.00169BAMBI+FALSE
chr1118502685TA0.00333WDR3,SPAG17+,-FALSE
chr117998CT0.00194WASH7P-FALSE
chr5122165472CT0.00147SNX2+FALSE(AC)nSINE,Alu
chr1183105705GA0.00074LAMC1+FALSE
chr1421929014TC0.00749RAB2B-TRUEAluSpSINE,Alu
chr2218572730AG6.64824E-05PEX26+TRUEAluYf1SINE,Alu
chr119543456TC0.00011LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr2201774264TC0.00639.FALSEAluSzSINE,Alu
chr1954627915CT0.00015PRPF31+FALSE
chr425236017TC2.76644E-09PI4K2B+FALSE
chr116944953TG0.00158CROCCP2-FALSE
chr269689806TC0.00175AAK1-TRUEAluSgSINE,Alu
chr1155582104TA0.00099MSTO1+FALSE
chr1182569291AT0.00979RGS16-FALSE
chr138326700TC5.61462E-05INPP5B-TRUEAluJrSINE,Alu
chr116529016CT0.00024ARHGEF19-FALSE
chr116890598TA0.00428NBPF1-FALSE
chr17980667TC0.00584TNFRSF9-TRUEAluJbSINE,Alu
chr146828657CT0.00378NSUN4+FALSE
chr3105266274TC4.07026E-07ALCAM+FALSE
chr1144918957TA0.00484NBPF20,PDE4DIP+,-FALSE
chr1214524576TC0.00060PTPN14-TRUEAluSgSINE,Alu
chr146828460CT0.00393NSUN4+FALSE
chr341281407GT0.00288CTNNB1+FALSE
chr968413593CA0.00342.FALSE
chr1154438880TC0.00170IL6R+FALSE
chr1298942808AG0.00019TMPO+TRUEAluScSINE,Alu
chr1179042580AG0.00995FAM20B+TRUEAluSx1SINE,Alu
chr2102484487GT0.00281MAP4K4+FALSE
chr386994021TC0.00705VGLL3-FALSE
chr129848629AG0.00027CLEC2D+FALSE
chr1229652587TC0.00732ABCB10-FALSE
chr2174090321CA0.00563ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr1119184951GA0.00066ZDHHC13+FALSE
chr525415881TC0.00911.FALSE
chr128826085AG0.00212PHACTR4+TRUEAluJbSINE,Alu
chr595130804CT0.00792RHOBTB3+FALSEAluSzSINE,Alu
chr116889639TC0.00350NBPF1-TRUE
chr5130540369CA0.00196LYRM7+FALSETigger4aSINE,Alu
chr1180169330CT0.00015FLJ23867+FALSEMIRSINE,Alu
chr2101622884CA0.00387RPL31+FALSE
chr674133914TC0.00014.FALSEAluYSINE,Alu
chr310302172GA0.00202TATDN2+FALSE
chr115993713AT7.45571E-05.FALSEAluSx4SINE,Alu
chr537290492TC8.25709E-07.FALSEAluSzSINE,Alu
chr110519888TC0.00878.FALSEAluJrSINE,Alu
chr124022910GA0.00702RPL11+FALSE
chr1161559466CA0.00491FCGR2C+FALSE
chr1474388908TC0.00835ZNF410+FALSE
chr540715440AC0.00646TTC33-FALSE
chr1145511998AG0.00715NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr152882970AG0.00533PRPF38A+FALSE
chr1205687351TC2.02150E-05NUCKS1-FALSE(T)nSINE,Alu
chr120977599CG0.00489PINK1,PINK1-AS+,-FALSE
chr138174583AC0.00644CDCA8+FALSE
chr1160965379TC0.00081F11R-TRUEAluScSINE,Alu
chr2101622700AG0.00387RPL31+FALSE
chr1205056476TC0.00096RBBP5-FALSEAluSxSINE,Alu
chr1120839681CA0.00125FAM72B+FALSE
chr1202993198CA0.00754TMEM183A+FALSE
chr1100731820GA0.00771RTCA+FALSE
chr138326547CT0.00212INPP5B-FALSEAluJrSINE,Alu
chr5151041877CA1.29615E-05SPARC-FALSE
chr642856917AG0.00280RPL7L1+TRUEAluSpSINE,Alu
chr3194124624CT0.00502ATP13A3-FALSE
chr237334146TC0.00039EIF2AK2-TRUEAluSzSINE,Alu
chr1298943103AG0.00306TMPO+TRUEAluSzSINE,Alu
chr1224380498AG6.58460E-05DEGS1+TRUEAluSxSINE,Alu
chr1431916770TC0.00153LOC101927124,DTD2+,-FALSEAluSc8SINE,Alu
chr126801731GT0.00325HMGN2+FALSE(T)nSINE,Alu
chr39517369CT0.00395SETD5+FALSE
chr1145512078AG0.00099NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr119542250TC0.00859LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr744917351TC0.00338PURB-TRUEAluSzSINE,Alu
chr1109181304CA0.00592FAM102B+FALSE
chr226612465GA0.00270EPT1+FALSE
chr312613866TC0.00043MKRN2+FALSE
chr193827764AG0.00056DR1+FALSE
chr110517635TC0.00553.FALSEAluSx1SINE,Alu
chr167874696TC0.00420SERBP1-TRUEAluSx3SINE,Alu
chr9136209398GA0.00150MED22-FALSE
chr186118417TG0.00653ZNHIT6-FALSE
chr1145293469GC0.00888NBPF20,NBPF10+FALSE
chr1684778690CT0.00799USP10+FALSE
chr642094498TC0.00931C6orf132-TRUEAluSq2SINE,Alu
chr11345002AG0.00141.FALSEAluSgSINE,Alu
chr1738788606GT1.11022E-15SMARCE1-FALSE
chr1266546100AG0.00849TMBIM4-FALSE
chr725161424TC0.00669CYCS-TRUEAluSz6SINE,Alu
chr1474526945TC2.53258E-07BBOF1,ALDH6A1+,-FALSEAluJoSINE,Alu
chr120976759CT2.31016E-05PINK1,PINK1-AS+,-FALSE
chr129508350CT0.00859SRSF4-FALSE(GGC)nSINE,Alu
chr1153617980AG0.00272CHTOP+FALSE
chr1298942824AG2.17067E-06TMPO+TRUEAluScSINE,Alu
chr1148251952CA0.00905NBPF8,NBPF14,NBPF9-FALSE
chr1202992954TC0.00042TMEM183A+FALSE
chr145244413TA0.00750.FALSE
chr6150047376TC0.00102NUP43-TRUEAluScSINE,Alu
chr2176790393CT0.00282LNPK-FALSEAluSpSINE,Alu
chr110519912TC0.00750.FALSEAluJrSINE,Alu
chr16948076CT0.00221CAMTA1+FALSEL2aSINE,Alu
chr128939803CT1.27013E-09TAF12-FALSE
chr3179116220TC0.00343GNB4-TRUEAluSz6SINE,Alu
chr314986447TC2.03372E-08FGD5-AS1-TRUEAluSq2SINE,Alu
chr1110201699TC0.00513GSTM4+FALSE
chr453732381CT0.00433RASL11B+FALSE(TTTCTTT)nSINE,Alu
chr840011786CA0.00196C8orf4+FALSE
chr224224134AG0.00333.FALSEAluSpSINE,Alu
chr310005159AT0.00939EMC3-FALSE(AT)nSINE,Alu
chr6109001947AG0.00359FOXO3+FALSE(A)nSINE,Alu
chr310193743TC0.00456VHL+FALSEAluJrSINE,Alu
chr1109474776AG0.00088GPSM2,CLCC1+,-FALSEAluSzSINE,Alu
chr133071159AG0.00947ZBTB8A+TRUEAluSx1SINE,Alu
chr1201975173GT0.00053RNPEP+FALSE
chr348787640TC0.00320PRKAR2A-TRUEAluSpSINE,Alu
chr237331560TC6.28398E-05.FALSEAluJbSINE,Alu
chr2176789478TC0.00219LNPK-TRUEMSTB1SINE,Alu
chr126603883GA0.00088CEP85+FALSE
chr2217366541AG0.00071.FALSEAluSzSINE,Alu
chr110519048TC0.00728.FALSEAluSx3SINE,Alu
chr2218571431AG0.00158PEX26+TRUEAluSzSINE,Alu
chr7120740103GT0.00601CPED1+FALSE
chr153291435AG0.00790ZYG11B+TRUEAluJrSINE,Alu
chr121086062GT0.00847RAD52-FALSEL2SINE,Alu
chr1916661421TC0.00427SLC35E1-TRUEAluSzSINE,Alu
chr413583889TC2.08207E-10BOD1L1-FALSE
chr315296358AT4.17447E-06SH3BP5,SH3BP5-AS1+,-FALSE
chr1742879245TC0.00834GJC1-TRUEAluSx1SINE,Alu
chr388104073GC0.00887CGGBP1-FALSE
chr3179117646GA0.00812GNB4-FALSE
chr1150937961AC0.00060CERS2-FALSEG-richSINE,Alu
chr5115165591TC0.00407ATG12-TRUEAluSq2SINE,Alu
chr116892135GA0.00221NBPF1-FALSE
chr261386572CG0.00821C2orf74+FALSEAluSzSINE,Alu
chr1160966376TC0.00996F11R-TRUEAluSgSINE,Alu
chr165297861TC0.00895RAVER2+FALSE
chr1153963246GA6.32081E-05RPS27+FALSE
chr7100031495CT0.00475MEPCE+FALSE
chr178483452CT0.00045DNAJB4+FALSEL1MB7SINE,Alu
chr398518158AT1.44910E-06DCBLD2-FALSE
chr13730400TC0.00457CEP104-TRUEAluSx3SINE,Alu
chr342252924GC0.00079TRAK1+FALSE
chr1148251083TC0.00041NBPF8,NBPF14,NBPF9-FALSEL1MC4SINE,Alu
chr1165877575AC0.00839UCK2+FALSE
chr247398328GA0.00434CALM2-FALSE
chr1145513114AG0.00026NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr766105163CG0.00594KCTD7+FALSE
chr2204301753TA0.00012RAPH1-FALSE
chr1148251079TC0.00880NBPF8,NBPF14,NBPF9-FALSEL1MC4SINE,Alu
chr186049362CA0.00140CYR61+FALSE
chr5130537666AG0.00329LYRM7+TRUEAluJbSINE,Alu
chr2152132130AG6.12116E-05NMI-FALSE
chr14102547384AT0.00403HSP90AA1-FALSE
chr1150446673AG2.11627E-07RPRD2+FALSE
chr165147002CT6.62669E-07CACHD1+FALSE
chr1149819554TC0.00137.FALSEMLT1C2SINE,Alu
chr1681064629AG6.04166E-07CENPN+TRUEAluSgSINE,Alu
chr3191115082GC0.00980CCDC50+FALSE
chr119586520AG0.00305MRTO4+TRUEAluSzSINE,Alu
chr1475202532AG1.20675E-07FCF1+TRUEAluScSINE,Alu
chr1179326296AG0.00171SOAT1+TRUE
chr2201676441GA0.00140LOC101927795,BZW1+,-FALSE
chr72274221TC0.00579MRM2-TRUEAluJrSINE,Alu

Differential Expression Gene Analysis