Dataset Overview
RBPRBFOX2
Knock-MethodshRNA
RBP FamilyFox-1_C
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR767LLP
PlatformHiSeq
Pubmed ID32252787

RBFOX2 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of RBFOX2
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of RBFOX2


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr19162224TC0.00523.FALSEAluSxSINE,Alu
chr1145586403GT0.00075NBPF20,NBPF10,PIAS3+FALSE
chr2113287200CT0.00087TTL+FALSE(T)nSINE,Alu
chr1101444071GA0.00963SLC30A7+FALSEMIR3SINE,Alu
chr132742441GA2.50972E-10LCK+FALSE
chr7138740037GC0.00598ZC3HAV1-FALSE
chr1563356574GA0.00845TPM1+FALSE
chr417803026TC0.00396DCAF16-TRUEAluSzSINE,Alu
chr116576295GA0.00139FBXO42-FALSEA-richSINE,Alu
chr136024788CT5.60663E-14NCDN+FALSE
chr136602178AT0.00764TRAPPC3-FALSE
chr642045545AG0.00440TAF8+TRUEAluSzSINE,Alu
chr46302519GA0.00195WFS1+FALSE
chr1160967890TC0.00876F11R-TRUEAluSpSINE,Alu
chr138280010CT0.00393MTF1-FALSE
chr23592638TC0.00941RNASEH1-TRUEAluSz6SINE,Alu
chr1207247477TC2.68116E-05PFKFB2+FALSEMER5BSINE,Alu
chr19331254AG0.00793H6PD+TRUEAluSxSINE,Alu
chr42940085TC8.20099E-05NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr193804952GA0.00421CCDC18-AS1-FALSE
chr237331546TC0.00936.FALSEAluJbSINE,Alu
chr1753470462CT0.00230MMD-FALSE
chr110520532TC0.00142.FALSEAluSx1SINE,Alu
chr1145375869GA0.00480NBPF20,NBPF10+FALSE
chr3160969268CT0.00835NMD3+FALSE
chr165147002CT6.62669E-07CACHD1+FALSE
chr3120115286TG0.00077FSTL1-FALSE
chr1675479474TC2.06057E-06TMEM170A-TRUEAluJbSINE,Alu
chr299812988AG8.76694E-05MRPL30+TRUEAluJbSINE,Alu
chr116112795AG0.00499FBLIM1+FALSE
chr2206861649TA0.00066INO80D-FALSE
chr2215674224GA9.97816E-05BARD1-FALSE
chr1109855150AC0.00251SORT1-FALSEA-richSINE,Alu
chr112058869CT0.00027MFN2+FALSE
chr110519912TC0.00750.FALSEAluJrSINE,Alu
chr1183596136AG0.00123ARPC5-FALSE
chr1206579936AG0.00424SRGAP2+FALSE
chr136067886TC0.00925PSMB2-TRUEAluSzSINE,Alu
chr598128999GA0.00663RGMB+FALSE
chr119542455TC0.00048LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr168167935AG0.00390GNG12-FALSE
chr13731965GA0.00209CEP104-FALSE
chr119934900GA0.00605MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr2217366570AG0.00332.FALSEAluSzSINE,Alu
chr299813003AG0.00370MRPL30+TRUEAluJbSINE,Alu
chr244459528GA0.00100PPM1B+FALSE
chr1168214098TG0.00134.FALSE
chr1949619561TC2.39173E-05LIN7B+FALSE
chr153291382AG0.00114ZYG11B+TRUEAluJrSINE,Alu
chr1144598755GA0.00044NBPF20+FALSE
chr4144442611TC0.00899SMARCA5+FALSE
chr167874731TC0.00125SERBP1-TRUEAluSx3SINE,Alu
chr2206983267TC0.00133.FALSEAluJbSINE,Alu
chr197116159GT0.00368INSR-FALSE
chr136068295TC2.11660E-05PSMB2-TRUEAluScSINE,Alu
chr123381596TC0.00762KDM1A+FALSE
chr3195962244GT0.00083.FALSE
chr1155106227AT0.00214EFNA1+FALSE
chr371005566CT0.00209FOXP1-FALSE(T)nSINE,Alu
chr3196662641TC0.00089NCBP2-FALSE
chr2217366195CA0.00929.FALSE
chr1053456599AG0.00339PRKG1,CSTF2T+,-FALSE
chr1256510709GA0.00047RPL41+FALSE
chr2180810264AT1.24157E-05CWC22-FALSE
chr1552203664AC0.01000TMOD3+FALSE
chr3186505900TG1.87786E-07EIF4A2+FALSE
chr194352553CT0.00136GCLM-FALSEAluSx1SINE,Alu
chr1942375554AG0.00458.FALSEAluSxSINE,Alu
chr189648329TC0.00093GBP4-TRUEAluYg6SINE,Alu
chr2035521047TA0.00064TLDC2,SAMHD1+,-FALSE
chr1419686228CT0.00106DUXAP10+FALSE
chr110519912TC0.00185.FALSEAluJrSINE,Alu
chr1153587308CT0.00077S100A14-FALSE
chr286364710TC0.00273PTCD3+FALSE
chr11595527TC0.00139CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr51574319TA0.00158SDHAP3-FALSE
chr5125961649AG3.29658E-05PHAX+TRUEAluSz6SINE,Alu
chr2113289701TG0.00994TTL+FALSE
chr1120839682AG0.00073FAM72B+FALSE
chr119585493AG3.52757E-05MRTO4+TRUEAluSc8SINE,Alu
chr51317949CT0.00173CLPTM1L-FALSE
chr116889414TC0.00384NBPF1-TRUEL1MC4SINE,Alu
chr256611541GA0.00521CCDC85A+FALSE
chr261705068AT0.00103.FALSE
chr145244411CA0.00362RPS8+FALSE
chr1155429590GT0.00356ASH1L-FALSE
chr1423300663GA0.00120MRPL52+FALSEMIRbSINE,Alu
chr1117530213GT0.00256PTGFRN+FALSE
chr110520153TC0.00907.FALSEAluSxSINE,Alu
chr646128910AG0.00782ENPP5-FALSE(GT)nSINE,Alu
chr1648387238AG0.00013LONP2,MIR5095+TRUEAluJbSINE,Alu
chr1757281125AG0.00204PRR11+TRUEAluSzSINE,Alu
chr126901090CT0.00952RPS6KA1+FALSE
chr2216148871TG0.00071.FALSETigger1SINE,Alu
chr145975266AG0.00188MMACHC+TRUEAluSg7SINE,Alu
chr1162354203AG0.00956C1orf226+FALSE
chr590074268GA0.00240ADGRV1+FALSE
chr1184761312TC0.00443FAM129A-TRUEAluJoSINE,Alu
chr417802819TC0.00316DCAF16-TRUEAluSzSINE,Alu
chr11572530AC0.00425CDK11B-FALSE
chr540835311AT0.00632RPL37-FALSE
chr19161365TC4.68504E-05.FALSEAluSxSINE,Alu
chr1118503786AG0.00135SPAG17-FALSEAluSx3SINE,Alu
chr38922054TC0.00464RAD18-FALSE
chr1156565045CA0.00995GPATCH4-FALSE
chr191981317TA0.00539CSNK1G2+FALSE
chr132638906CT5.73102E-10KPNA6+FALSE
chr717384395AG0.00856AHR+TRUEAluSxSINE,Alu
chr613788342TC0.00048MCUR1-TRUEAluSxSINE,Alu
chr339137793CT0.00363WDR48+FALSE
chr119586455AG0.00772MRTO4+TRUEAluSzSINE,Alu
chr110517688TC0.00020.FALSEAluSx1SINE,Alu
chr3123332546CG0.00964MYLK-AS1,MYLK+,-FALSE
chr246524711CT0.00513EPAS1+FALSE
chr146075783AG0.00755NASP+TRUEAluSx4SINE,Alu
chr189447856AG0.00465KYAT3,RBMXL1-FALSE
chr136531781GA0.00288.FALSE
chr349142142GT6.70614E-05QARS-FALSE
chr315114759GA1.99109E-05RBSN-FALSE
chr1569492TC0.00336.FALSE
chr128826085AG0.00281PHACTR4+TRUEAluJbSINE,Alu
chr1567783TC0.00817MIR6723-FALSE
chr142886523TC0.00649RIMKLA+FALSEMIRcSINE,Alu
chr131426815AG0.00797PUM1-FALSE
chr5130540369CA0.00196LYRM7+FALSETigger4aSINE,Alu
chr777409288AG7.47972E-05.FALSEAluScSINE,Alu
chr1565442506TC0.00088CLPX-TRUEAluSg4SINE,Alu
chr629704336GA0.00207.FALSEL1ME3ASINE,Alu
chr119542463TC0.00060LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr310193732AG0.00472VHL+TRUEAluJrSINE,Alu
chr126604691GC0.00043CEP85+FALSE
chr264687665CA0.00976LGALSL+FALSE
chr1680636808CT0.00881CDYL2-FALSE
chr285772404CA0.00015GGCX-FALSE
chr42940371TC0.00905NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr131902343TC1.48709E-05SERINC2+FALSE
chr349397323TC0.00000RHOA-TRUE
chr2242384368GA0.00096FARP2+FALSEAluJrSINE,Alu
chr185733095GA0.00651BCL10-FALSE
chr165897981GA0.00025LEPR,LEPROT+FALSE
chr315114385TC0.00146RBSN-TRUEAluYSINE,Alu
chr439550981TC5.85020E-07UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr159004766GT0.00213OMA1-FALSE
chr110521172TC1.01590E-06DFFA-TRUEAluYSINE,Alu
chr140214333AG0.00112PPIE+TRUEAluSq2SINE,Alu
chr271298486TC0.00408NAGK+FALSE
chr1675479467TC0.00160TMEM170A-TRUEAluJbSINE,Alu
chr4120979673TC0.00074.FALSEAluSgSINE,Alu
chr19163290TC0.00130.FALSEAluSpSINE,Alu
chr250147865TA0.00112NRXN1-FALSE(GT)nSINE,Alu
chr111982580GA2.06927E-05KIAA2013-FALSE
chr310005392TC8.76084E-06EMC3-FALSEAluSg7SINE,Alu
chr11119533726AG0.00169NECTIN1-FALSE
chr1145689025AG0.00541NBPF20,NBPF10+TRUEAluSc8SINE,Alu
chr41006333GA0.00117FGFRL1+FALSE(CTG)nSINE,Alu
chr111298093CT1.54321E-14MTOR-FALSE
chr133148214AG0.00734SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr115989141CG0.00364.FALSE
chr5118174757TC0.00032DTWD2-TRUEAluYSINE,Alu
chr131732602CA0.00336SNRNP40-FALSE
chr124022910GA0.00702RPL11+FALSE
chr381539382CT1.63276E-05GBE1-FALSE
chr128939803CT1.99823E-11TAF12-FALSE
chr124022914AG0.00347RPL11+FALSE
chr16354955GA0.00282ACOT7-FALSE
chr1120101744CA0.00540NAV2+FALSE
chr1149913733TC0.00143OTUD7B-TRUEMER96BSINE,Alu
chr1211918115CT0.00979LPGAT1-FALSEMER63DSINE,Alu
chr1201845903AG0.00041IPO9+FALSE
chr29629954TC0.00308ADAM17-FALSE
chr229135468CG0.00262WDR43+FALSE
chr285132775CG7.25564E-06TMSB10+FALSE
chr110520117TC0.00188.FALSEAluSxSINE,Alu
chr116890176AC0.00753NBPF1-FALSE
chr345266555TC1.22536E-07TMEM158-FALSE
chr116889575TC0.00969NBPF1-TRUE
chr1569991TG0.00980.FALSE
chr132799508AC8.53764E-05MARCKSL1-FALSE
chr2191799592AG0.00010GLS+TRUE
chr4169911126CA0.00122CBR4-FALSE
chr1205737659CT0.00024RAB29-FALSEAluSq2SINE,Alu
chr136068166TC0.00686PSMB2-TRUEAluScSINE,Alu
chr2220406239TG0.00014CHPF-FALSEMIRbSINE,Alu
chr1158631171AC0.00815SPTA1-FALSE
chr1207219603TC0.00341YOD1-FALSE
chr348787042TC1.97898E-05PRKAR2A-TRUEAluSx3SINE,Alu
chr1144614931GA0.00469NBPF20+FALSE
chr123636031TA0.00965HNRNPR-FALSE
chr1145512944AG0.00171NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1121133779CG2.29819E-05SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr136770605CT8.58098E-05THRAP3+FALSE(T)nSINE,Alu
chr261764916AC0.00189XPO1-FALSE(AC)nSINE,Alu
chr131837516GC5.10721E-05ZCCHC17+FALSE
chr1144902696AT0.00997NBPF20,PDE4DIP+,-FALSE
chr2183642878GA0.00373DNAJC10+FALSE
chr1203277245GA0.00115BTG2+FALSE
chr2035521048AT0.00727TLDC2,SAMHD1+,-FALSE
chr2216903544TC0.00929PECR-TRUEAluSx3SINE,Alu
chr1563445744AT0.00539RPS27L-FALSE
chr299812429AG0.00504MRPL30+TRUEAluSxSINE,Alu
chr410443059AT0.00187ZNF518B-FALSE
chrX2824916TC6.31541E-06ARSD-TRUEAluSx1SINE,Alu
chr116889050AC0.00669NBPF1-FALSE
chr128835847AG4.14471E-06SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr237328082TC1.18454E-08.FALSE
chr1112266790CT0.00892FAM212B-FALSE
chr1153591278GT0.00119S100A13-FALSE
chr2198572076AC0.00532MARS2+FALSE
chr2208619742AG0.00500CCNYL1+TRUEAluJbSINE,Alu
chr410076658TC6.66134E-16WDR1-FALSE
chr116933629AG0.00310NBPF1-FALSEGA-richSINE,Alu
chr1180943529CT0.00297STX6-FALSE
chr255516911AG0.00719CCDC88A-FALSE(GA)nSINE,Alu
chr1156084582TC0.00195LMNA+FALSE
chr372424929AG0.00988RYBP-FALSE
chr3188602081AC7.06828E-05LPP+FALSEMIRcSINE,Alu
chr2221304408AG0.00967CRKL+FALSE
chr310302056AG0.00018TATDN2+FALSE
chr12125511242AG0.00015THRIL-FALSEAluSx1SINE,Alu
chr791502407CG0.00183MTERF1-FALSE
chr1847919174AG0.00820SKA1+TRUEAluYk4SINE,Alu
chr5125961611AG0.00113PHAX+TRUEAluSz6SINE,Alu
chr131905888CA0.00667SERINC2+FALSE
chr1203822584TC5.41257E-07ZC3H11A+FALSE
chr1145291494AG0.00738NBPF20+FALSEMIRbSINE,Alu
chr1201350983CT0.00768LAD1-FALSE
chr165900357GT0.00041LEPR,LEPROT+FALSE
chr439550978TC0.00023UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr11595602AG9.14189E-05CDK11B,SLC35E2B-FALSEAluJrSINE,Alu
chr1144932199CA0.00584NBPF20,PDE4DIP+,-FALSE
chr345153708GA4.36430E-08CDCP1-FALSE
chr1109746728AG0.00171KIAA1324+TRUEAluJbSINE,Alu
chr1169101269TG0.00207ATP1B1+FALSE(T)nSINE,Alu
chr116945409TA0.00105CROCCP2-FALSE
chr826492397CT0.00709DPYSL2+FALSE
chr223865260TC0.00262KLHL29+FALSE
chr42940413TC0.00311NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr720178562TC1.84789E-06MACC1,LOC101927668-TRUEAluYSINE,Alu
chr1180991777TC0.00629STX6-FALSE
chr11118880839AG0.00922CCDC84+TRUEAluJbSINE,Alu
chr47761211CT8.70555E-11AFAP1,AFAP1-AS1+,-FALSE
chr116841561GA0.00025.FALSE
chr1145281633CA0.00059NBPF20,NOTCH2NL+FALSE
chr110520154TC0.00380.FALSEAluSxSINE,Alu
chr3148748339GT0.00666HLTF-FALSE
chrM9988TC0.00011.FALSE
chr642856156AG0.00105RPL7L1+TRUEAluSzSINE,Alu
chr110518733TC0.00541.FALSEAluSx1SINE,Alu
chr11595540TC0.00048CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr1155695985AG0.00031DAP3+TRUEAluSpSINE,Alu
chr1120458004AT0.00247NOTCH2-FALSE
chr440138676AG0.00157N4BP2+FALSE
chr124933701AG0.00372NCMAP+TRUEAluJrSINE,Alu
chr237329352TC0.00403.FALSEAluJr4SINE,Alu
chr237075013TA0.00754STRN-FALSE
chr74809333AG0.00067FOXK1+TRUEAluSx1SINE,Alu
chr1161338504CG0.00343.FALSE
chr899053985TG4.76792E-05RPL30-FALSE
chr1225706943CT0.00229ENAH-FALSE
chr310192744AG3.36147E-05VHL+TRUEAluSx1SINE,Alu
chr145975269AG0.00827MMACHC+TRUEAluSg7SINE,Alu
chr132373437GA3.32434E-12PTP4A2-FALSE
chr2114352238GA1.72390E-05WASH2P+FALSE
chr128825427AG0.00484PHACTR4+TRUEAluSgSINE,Alu
chr473923605TC0.00366COX18-TRUEAluSq2SINE,Alu
chr1194801637TC0.00726SRSF8+FALSE
chr1958374130CT0.00124ZNF587+FALSE

Differential Expression Gene Analysis