Dataset Overview
RBPGPKOW
Knock-MethodshRNA
RBP FamilyKOW
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR968YWY
PlatformHiSeq
Pubmed ID32252787

GPKOW - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of GPKOW
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of GPKOW


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1231398555AG0.00401GNPAT+FALSE
chr11662754TC0.00856SLC35E2-TRUEAluYSINE,Alu
chr744841239TA0.00199PPIA+FALSE
chr119543465TC0.00117LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr125812110TC0.00639TMEM57+FALSE
chr5150827307GT0.00708SLC36A1+FALSE
chr135648710GC0.00377SFPQ-FALSE
chr2120439459CA0.00273TMEM177+FALSE
chr652860743TG1.01575E-05.FALSE7SKSINE,Alu
chr315113736TC0.00641RBSN-TRUEAluSz6SINE,Alu
chr131342611AC0.00145SDC3-FALSE
chr333138549GA0.00612GLB1-FALSE
chr1118066459AG1.18472E-05MAN1A2+FALSE
chr286979093GA0.00591RMND5A+FALSE
chr2206986926TC0.00913.FALSEAluJrSINE,Alu
chr1152884247AG0.00642IVL+FALSE
chr16282301TC0.00480ICMT-TRUEAluSzSINE,Alu
chr211674374AG0.00559GREB1+FALSETigger9bSINE,Alu
chr146828700AG0.00012NSUN4+FALSE
chr128826023AG0.00342PHACTR4+FALSEAluJbSINE,Alu
chr643582795AG0.00087POLH+TRUEAluSx1SINE,Alu
chr16683582CA0.00152PHF13+FALSE
chr128662057AG3.94650E-05MED18+TRUEAluSq2SINE,Alu
chr1148561089TC0.00975NBPF15+FALSE
chr1269237056AG0.00372MDM2+TRUE
chr1100490000AG0.00066SLC35A3+TRUEAluSgSINE,Alu
chr153711218AT0.00838LRP8-FALSE
chr2110373938TG0.00413SOWAHC+FALSE(GAAT)nSINE,Alu
chr1942375584AG0.00021.FALSEAluSxSINE,Alu
chr138174583AC0.00644CDCA8+FALSE
chr110519048TC0.00089.FALSEAluSx3SINE,Alu
chr1204521576AG0.00021MDM4+TRUEAluSgSINE,Alu
chr344487862GA0.00262ZNF445-FALSE
chr110520692TC0.00973DFFA-TRUEAluSc8SINE,Alu
chr3156259229TC0.00225SSR3-TRUEAluSq2SINE,Alu
chr237431485AG0.00339CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr1423795204GT0.00938BCL2L2-PABPN1,PABPN1+FALSE
chr2102484490GT0.00635MAP4K4+FALSE
chr124999101GT0.00100SRRM1+FALSE
chr2238499528TG0.00332RAB17-FALSE
chr1168169452GA0.00600TIPRL+FALSE
chr2131131424GC0.00845PTPN18+FALSE
chr1918475356AG0.00360PGPEP1+TRUEAluSx1SINE,Alu
chr1421929014TC0.00749RAB2B-TRUEAluSpSINE,Alu
chr457801196GA0.00485REST+FALSE
chr1183515428GA0.00232SMG7+FALSE
chr122419433TG0.00200CDC42+FALSE
chr2178406765TA0.00325AGPS+FALSE
chr15102512797AG0.00080WASH3P+FALSE
chr119543247TC5.35430E-06LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr179110518AG0.00997IFI44L+FALSE
chr195658344GA0.00100TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr1780899281GA0.00053TBCD+FALSE
chr4119553307TC0.00096LOC729218+FALSE
chr1033189606AG0.00011ITGB1-FALSE
chr756079033TC0.00300PSPH-TRUEAluYm1SINE,Alu
chr8143739343TC0.00999JRK-FALSE
chr131905889AG0.00565SERINC2+FALSE
chr1117945049GA0.00030MAN1A2+FALSE
chr2105881071CA0.00851TGFBRAP1-FALSE
chr4186081819CT3.85218E-06CFAP97-FALSE
chr914810CG0.00709WASH1-FALSE
chr1118502732CT0.00151WDR3,SPAG17+,-FALSE
chr5178508569CT0.00571ZNF354C+FALSE
chr116891333CT0.00011NBPF1-FALSE
chr136067749TC0.00748PSMB2-TRUEAluSzSINE,Alu
chr116945504CT0.00665CROCCP2-FALSE
chr110520099TC6.30717E-05.FALSEAluSxSINE,Alu
chr6160100882TC0.00494SOD2-TRUEAluSzSINE,Alu
chr13730400TC0.00584CEP104-TRUEAluSx3SINE,Alu
chr732529936GC0.00027LSM5-FALSE
chr116892277GT0.00164NBPF1-FALSE
chr1113672691AG0.00515.FALSEAluJbSINE,Alu
chr5149364144AG0.00014SLC26A2+TRUEAluSc8SINE,Alu
chr1109180686CT1.31584E-05FAM102B+FALSE
chr110520684TC0.00842DFFA-TRUEAluSc8SINE,Alu
chr540832555AT5.95918E-06RPL37-FALSE
chr226613948AG0.00218EPT1+FALSE
chr1298943192AG0.00011TMPO+FALSEAluSzSINE,Alu
chr237330435TC3.14905E-06.FALSEAluSq2SINE,Alu
chr153291344AG0.00088ZYG11B+FALSE(A)nSINE,Alu
chr1610623553TC0.00024EMP2-TRUEAluSpSINE,Alu
chr1109967950TA0.00096PSMA5-FALSE
chr5125961816AG0.00013PHAX+TRUEFLAM_CSINE,Alu
chr642060429TC0.00017.FALSEAluSz6SINE,Alu
chr1145369556AG0.00373NBPF20,NBPF10+TRUEL1MC4SINE,Alu
chr2203744658TC0.00112.FALSEAluSx1SINE,Alu
chr1200521412GA0.00110KIF14-FALSE
chr110221302GA0.00119UBE4B+FALSE
chr4103809328GT0.00284CISD2,SLC9B1+,-FALSE
chr138327545TC0.00602INPP5B-TRUEAluSx3SINE,Alu
chr132799508AC8.53764E-05MARCKSL1-FALSE
chr1207943325AG0.00158CD46+TRUEAluSx1SINE,Alu
chr237330517TC0.00324.FALSEAluSq2SINE,Alu
chr239212565TG0.00662SOS1-FALSE
chr128662254AG0.00290MED18+TRUEAluSq2SINE,Alu
chr2174090338AC0.00250ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr8143763622CT0.00470PSCA+FALSE
chr1256815652CT1.92663E-05TIMELESS-FALSE
chr10121588038AC0.00100INPP5F+FALSE
chr375475670AC0.00506FAM86DP-FALSE
chr11337841CA0.00186MRPL20-FALSE
chr131345785TA0.00962SDC3-FALSE
chr1900720AT0.00065KLHL17+FALSE(TTTA)nSINE,Alu
chr1924104040AG0.00476ZNF726+TRUEAluSg4SINE,Alu
chr5134086670CA0.00585CAMLG+FALSE
chr1114226255GA0.00381MAGI3+FALSE
chr237330507TC9.86666E-05.FALSEAluSq2SINE,Alu
chr7102277600TC0.00240POLR2J2,UPK3BL-TRUEAluScSINE,Alu
chr2128604232AT0.00652POLR2D-FALSE
chr77283569GA0.00032C1GALT1+FALSE(AT)nSINE,Alu
chr1211918115CT7.42155E-06LPGAT1-FALSEMER63DSINE,Alu
chr2203744240TC0.00595.FALSEAluSxSINE,Alu
chr11477244TC0.00365SSU72-FALSE
chr119585493AG3.52757E-05MRTO4+TRUEAluSc8SINE,Alu
chr152520867TA7.48778E-05TXNDC12-FALSE
chr1533064148TC1.59288E-05FMN1-FALSE
chr195362514GT0.00279CNN3-FALSE
chr1165877575AC0.00675UCK2+FALSE
chr126755643AG0.00068LIN28A+FALSEAluScSINE,Alu
chr11419888AG0.00630ATAD3B+TRUEAluSpSINE,Alu
chr3128215735GA0.00734GATA2-AS1+FALSE
chr224223159AG0.00717UBXN2A+TRUEAluScSINE,Alu
chr153291420AG0.00011ZYG11B+TRUEAluJrSINE,Alu
chr842882287AG0.00771HOOK3+TRUEAluSx1SINE,Alu
chr236777209TC0.00299CRIM1+FALSE(TG)nSINE,Alu
chr1144521099AG0.00049NBPF20+FALSE
chr128826118AG0.00948PHACTR4+TRUEAluJbSINE,Alu
chr16477671GT0.00620HES2-FALSEAluSxSINE,Alu
chr151822219GA0.00223EPS15-FALSE
chr417629434AG0.00661.FALSEAluSx3SINE,Alu
chr1109192051TC0.00124HENMT1-TRUEAluJrSINE,Alu
chr1269237021AG0.00229MDM2+TRUE
chr117326540GA0.00120ATP13A2-FALSE
chr116890484GC0.00704NBPF1-FALSE
chr1765334766TC4.45484E-05PSMD12-TRUEAluSqSINE,Alu
chr5159520661TC0.00776PWWP2A-FALSE
chr12125512507AG0.00276.FALSEAluYSINE,Alu
chr110520117TC0.00188.FALSEAluSxSINE,Alu
chr1153907287GC0.00122DENND4B-FALSE(CTG)nSINE,Alu
chr2158636910GA0.00160ACVR1-FALSE
chr13745924GA0.00612CEP104-FALSE
chr193826611CG0.00072DR1+FALSE
chr11595077TC0.00031CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr410442610TC0.00174ZNF518B-FALSE
chr1590820068AG0.00194.FALSEAluYSINE,Alu
chr125894462AG0.00101LDLRAP1+FALSEMIRbSINE,Alu
chr1204521625AG0.00808MDM4+TRUEAluSgSINE,Alu
chr1749041897TC4.67707E-06SPAG9-TRUEAluSxSINE,Alu
chr1563356574GA0.00845TPM1+FALSE
chr119543456TC0.00386LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr146159809TA0.00605TMEM69+FALSE
chr1150937771TA0.00026CERS2-FALSE(ATTTTTT)nSINE,Alu
chr6150047430TC0.00568NUP43-TRUEAluScSINE,Alu
chr11717473AC0.00925GNB1-FALSE
chr132638096CT0.00857KPNA6+FALSE
chr1155161736GA0.00088MUC1-FALSE
chr1214529320TG0.00365PTPN14-FALSEAluJbSINE,Alu
chr2018468404TC0.00301RBBP9-TRUEAluSz6SINE,Alu
chr652860743TG1.89710E-05.FALSE7SKSINE,Alu
chr43770069GC0.00018ADRA2C+FALSE
chr1942375624AG0.00339.FALSEAluSxSINE,Alu
chr128661576AG0.00625MED18+TRUEAluSgSINE,Alu
chr1118068558GA0.00876.FALSE
chr1163394018CA0.00103ATL3-FALSE
chr1143398850GT0.00639.FALSE
chr1185014720AG0.00989RNF2+FALSE
chr5180682604AT0.00037CTC-338M12.4+FALSE
chr439552022TC0.00015UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr118707397TA0.00046RPL27A+FALSE
chr119984098CG0.00826MINOS1-NBL1,NBL1+FALSE
chr349396751TC0.00311RHOA-FALSE
chr114150116CT7.82303E-05PRDM2+FALSE
chr116933327CT6.62916E-05NBPF1-FALSE
chr1241795525AG0.00165OPN3,CHML-FALSETHE1BSINE,Alu
chr16683581AC0.00189PHF13+FALSE
chr1112003957GA0.01000ATP5F1+FALSEHelitron2Na_MamSINE,Alu
chr46689813CA0.00141.FALSEL2bSINE,Alu
chr1168218735AG0.00924.FALSEAluSzSINE,Alu
chr132637063CT0.00071KPNA6+FALSE
chrX123046290AG0.00524XIAP+TRUEAluJbSINE,Alu
chr315112630CT0.00017RBSN-FALSEAluSq2SINE,Alu
chr1180991776CA0.00664STX6-FALSE
chr115668319GA0.00489FHAD1+FALSE
chr422404391GA0.00338ADGRA3-FALSE
chr119542463TC0.00746LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr132661578CT0.00623TXLNA+FALSE(T)nSINE,Alu
chr1542860107AG0.00194HAUS2+TRUEAluSgSINE,Alu
chr417803545TC0.00710DCAF16-TRUEAluYSINE,Alu
chr457326291AG0.00279PAICS+TRUEAluJrSINE,Alu
chr1160966301TC8.33949E-06F11R-TRUEAluSgSINE,Alu
chr3183534913AG0.00367MAP6D1-FALSE
chr4177249593TG0.00038SPCS3+FALSE(T)nSINE,Alu
chr140705200GA3.20116E-08RLF+FALSE
chr123519110GA0.00268HTR1D-FALSEAluScSINE,Alu
chr110520219TC0.00201.FALSEAluSxSINE,Alu
chr1610623545TC0.00142EMP2-TRUEAluSpSINE,Alu
chr10104417853TA0.00393TRIM8+FALSE(AAT)nSINE,Alu
chr1936033460CT0.00622GAPDHS,TMEM147-AS1+,-FALSE
chr12160436CT0.00488SKI+FALSE(CGC)nSINE,Alu
chr286731654GA0.00931CHMP3,RNF103-CHMP3-FALSEAluJrSINE,Alu
chr642857179CA0.00492RPL7L1+FALSEAluSpSINE,Alu
chr35026729CT0.00539BHLHE40+FALSE
chr315456307TC0.00939METTL6-TRUEAluJrSINE,Alu
chr165898263AG0.00767LEPR,LEPROT+FALSEMIRcSINE,Alu
chr140229368AG0.00154BMP8B,PPIE+,-FALSE
chrM8859GA0.00929.FALSE
chr119953120GA0.00212MINOS1,MINOS1-NBL1+FALSE
chr1148558269AG0.00538NBPF15+FALSEAluJbSINE,Alu
chr4165998019TC0.00849TMEM192-TRUEAluSxSINE,Alu
chr116890607GA0.00869NBPF1-FALSE
chr5149823791GT0.00480.FALSE
chr153289759AG0.00060ZYG11B+TRUEAluSzSINE,Alu
chr1569874CT0.00076.FALSE
chr118707396CA0.00081RPL27A+FALSE
chr348787118TC0.00359PRKAR2A-TRUEAluSx3SINE,Alu
chr110517276TC0.00079.FALSEAluJrSINE,Alu
chr197084638AG0.00508ZNF557+TRUEAluJbSINE,Alu
chr210076828AG0.00026.FALSEAluJrSINE,Alu
chr1145292925CT0.00817NBPF20+FALSE
chr3196082911TC0.00250UBXN7-FALSE
chr1450053348GA0.00067.FALSE7SLRNASINE,Alu
chr119542631TC0.00031LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr296850885TC0.00699STARD7-FALSE
chr1179326588AG0.00563SOAT1+TRUEAluSgSINE,Alu
chr5149829071TC0.00407RPS14-FALSE
chr186119441GA0.00905ZNHIT6-FALSE
chr179125148GA0.00203IFI44+FALSE
chr556177849CG0.00921MAP3K1+FALSE(CAA)nSINE,Alu
chr111084103TA0.00162TARDBP+FALSE
chr192426238TG0.00129TIMM13,TMPRSS9+,-FALSE
chr190478690AC0.00035ZNF326+FALSE
chr255459824CT0.00763RPS27A+FALSE
chr2128061053AG0.00184MAP3K2-FALSE
chr220401854AT2.80783E-05SDC1-FALSE
chr1011912065CG0.00191PROSER2-AS1,PROSER2+,-FALSE
chr76064015AT0.00746EIF2AK1-FALSE
chr1128134974CA0.00479METTL15+FALSE
chr12133298121AG0.00026PGAM5+TRUEAluJoSINE,Alu
chr1965146GA0.00761WASH5P-FALSE

Differential Expression Gene Analysis