Dataset Overview
RBP
KHDRBS1
Knock-Method
shRNA
RBP Family
KH_1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR784FTX
Platform
HiSeq
Pubmed ID
32252787
KHDRBS1 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of KHDRBS1
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
15.89
20.05
0.51483
0.00016
0.00044
A1CF
30.66
27.89
-0.47580
1.52704E-09
9.49830E-09
A2M
2149.68
2578.72
0.30529
6.54945E-05
0.00020
AAAS
25.65
19.23
-0.53938
2.15993E-10
1.50409E-09
AADAT
4.81
2.5
-1.03483
1.92610E-12
1.75909E-11
AAGAB
8.9
5.92
-0.55477
9.29891E-07
3.85002E-06
AAK1
2.42
3.17
0.65748
1.00241E-06
4.12730E-06
AAMP
118.35
89.93
-0.21287
0.00731
0.01448
AAR2
19.98
16.72
-0.31429
9.88579E-05
0.00029
AARS
64.38
132.97
0.99811
3.09694E-33
1.81986E-31
Showing 1 to 10 of 8,400 entries
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Function Analysis of Target Genes of KHDRBS1
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACSM2B
20586743_20586829_20585446_20585967_20587528_20587606
0.00824
0.497
DataSet_01_220
View details
AFMID
76200711_76200822_76198783_76198832_76200908_76200933
0.00063
0.259
DataSet_01_220
View details
AFMID
76200736_76200822_76198783_76198832_76200908_76200933
0.00326
0.173
DataSet_01_220
View details
AHSG
186336079_186336280_186334975_186335139_186337645_186337729
0.00032
-0.171
DataSet_01_220
View details
AHSG
186336079_186336177_186334975_186335139_186336324_186336426
0.00861
-0.007
DataSet_01_220
View details
AK2
33497144_33497262_33490042_33490168_33502336_33502503
0.00400
0.025
DataSet_01_220
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ALB
74270837_74271056_74270003_74270123_74272345_74272478
0.00012
-0.045
DataSet_01_220
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ALDH3A2
19576463_19576588_19575033_19575269_19578808_19578812
0.00226
0.104
DataSet_01_220
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ANKLE2
133318394_133318575_133318004_133318071_133319739_133319862
0.00053
0.21
DataSet_01_220
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ANKRD10
111546455_111546549_111545044_111545610_111558379_111558471
0.00071
0.243
DataSet_01_220
View details
Showing 1 to 10 of 254 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9264754_9264807_9264904_9265132_9262909_9262930
0.00000
-0.211
DataSet_01_220
View details
ABCC2
101595900_101596047_101601723_101601850_101594136_101594292
0.00088
-0.022
DataSet_01_220
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ACSL1
185691408_185691486_185691552_185691630_185689469_185689604
0.00868
0.068
DataSet_01_220
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ACTN4
39200896_39200982_39201915_39202001_39200034_39200116
0.00041
-0.053
DataSet_01_220
View details
ADAM9
38940486_38940592_38948777_38948865_38940159_38940240
0.00000
0.241
DataSet_01_220
View details
AHSG
186334975_186335164_186337645_186337729_186334231_186334316
0.00000
0.114
DataSet_01_220
View details
AHSG
186336079_186336280_186336324_186336426_186334975_186335139
0.00000
-0.013
DataSet_01_220
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AHSG
186336324_186336426_186337645_186337729_186334231_186334316
0.00132
-0.007
DataSet_01_220
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AHSG
186336079_186336280_186336285_186336426_186334975_186335139
0.00147
-0.006
DataSet_01_220
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AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00171
-0.006
DataSet_01_220
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Showing 1 to 10 of 88 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACADM
76252384_76252601_76252384_76252482_76253181_76253260
0.00907
0.215
DataSet_01_220
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AP1G2
24035024_24035369_24035272_24035369_24034814_24034910
0.00988
-0.089
DataSet_01_220
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BTF3
72794232_72794411_72794232_72794383_72794958_72795027
0.00899
0.008
DataSet_01_220
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DDX56
44612161_44612343_44612172_44612343_44611945_44612036
0.00276
0.131
DataSet_01_220
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DICER1
95577643_95577793_95577653_95577793_95574660_95574840
0.00705
0.239
DataSet_01_220
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DNAJC16
15892576_15892905_15892576_15892675_15893593_15893764
0.00470
-0.132
DataSet_01_220
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ENO2
7025834_7025998_7025834_7025893_7026201_7026423
0.00366
-0.059
DataSet_01_220
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GRN
42428730_42428828_42428730_42428756_42428917_42429163
0.00375
-0.15
DataSet_01_220
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LRRC37BP1
28958772_28959117_28958772_28958945_28960115_28960408
0.00921
-0.207
DataSet_01_220
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ODAM
71066213_71066441_71066213_71066318_71067974_71068046
0.00030
0.345
DataSet_01_220
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Showing 1 to 10 of 17 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABLIM1
116207638_116207785_116207638_116207779_116211382_116211430
0.00978
-0.128
DataSet_01_220
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ACIN1
23533563_23533697_23533563_23533694_23535174_23535217
0.00222
0.074
DataSet_01_220
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APOA2
161192707_161192840_161192707_161192784_161193139_161193215
0.00390
-0.009
DataSet_01_220
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CCBL1
131600496_131600742_131600496_131600646_131607631_131607690
0.00684
-0.483
DataSet_01_220
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CHD4
6711125_6711341_6711125_6711320_6711541_6711663
0.00667
-0.136
DataSet_01_220
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CHD6
40101961_40102157_40101961_40102046_40111948_40112159
0.00684
-0.2
DataSet_01_220
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EIF3G
10229763_10229931_10229763_10229847_10230329_10230376
0.00794
0.013
DataSet_01_220
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EPS8L3
110294616_110294815_110294616_110294772_110295307_110295342
0.00014
0.073
DataSet_01_220
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FN1
216236631_216237098_216236631_216236738_216238044_216238134
0.00220
-0.005
DataSet_01_220
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FN1
216236831_216237047_216236831_216237023_216238044_216238134
0.00278
0.079
DataSet_01_220
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AMBRA1
46563494_46564948_46563494_46564531_46564801_46564948
0.00093
-0.281
DataSet_01_220
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ANKZF1
220098854_220100034_220098854_220099010_220099547_220100034
0.00084
-0.138
DataSet_01_220
View details
AP1G2
24034814_24035369_24034814_24034910_24035024_24035369
0.00044
0.099
DataSet_01_220
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AP1G2
24035024_24035369_24035024_24035101_24035272_24035369
0.00088
0.213
DataSet_01_220
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AP1G2
24030958_24031103_24030958_24030970_24031061_24031103
0.00303
-0.238
DataSet_01_220
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BCL2L1
30309457_30310400_30309457_30310133_30310219_30310400
0.00018
-0.151
DataSet_01_220
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CANT1
76993073_76994045_76993073_76993726_76993921_76994045
0.00300
0.24
DataSet_01_220
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CDC37
10505903_10506219_10505903_10506019_10506110_10506219
0.00092
0.073
DataSet_01_220
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CERS2
150939231_150939678_150939231_150939338_150939549_150939678
0.00199
0.015
DataSet_01_220
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DNAJC2
102962957_102963241_102962957_102963079_102963149_102963241
0.00513
0.143
DataSet_01_220
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
180991776
C
A
0.00664
STX6
-
FALSE
chr1
53289547
A
G
0.00646
ZYG11B
+
TRUE
AluSz
SINE,Alu
chr1
71531596
A
G
0.00016
ZRANB2-AS1,ZRANB2
+,-
FALSE
chr1
36067851
T
C
0.00269
PSMB2
-
TRUE
AluSz
SINE,Alu
chr1
26608009
T
A
0.00496
SH3BGRL3
+
FALSE
chr1
10421878
A
G
7.26627E-05
KIF1B
+
FALSE
chr1
36067838
T
C
1.55029E-07
PSMB2
-
TRUE
AluSz
SINE,Alu
chr1
144606838
A
G
0.00988
NBPF20
+
FALSE
chr1
17085028
G
A
0.00803
MST1L,LOC102724562
-
FALSE
chr1
39794147
A
C
9.03176E-05
MACF1
+
FALSE
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression