Dataset Overview
RBPCNOT7
Knock-MethodshRNA
RBP FamilyCAF1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR113PYX
PlatformHiSeq
Pubmed ID32252787

CNOT7 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of CNOT7
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of CNOT7


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr140537924GA0.00404CAP1+FALSE(A)nSINE,Alu
chr1939669597TC0.00610PAK4+FALSE(TG)nSINE,Alu
chr2128603114TC0.00143.FALSEAluSpSINE,Alu
chr132638096CT0.00857KPNA6+FALSE
chr1269237077AG0.00445MDM2+TRUE(GA)nSINE,Alu
chr317201882CT0.00259TBC1D5-FALSE
chr296934504TC0.00021CIAO1+FALSE
chr315114318TC0.00067RBSN-TRUEAluYSINE,Alu
chr189479063GA0.00076GBP3-FALSE
chr186852362CA0.00073ODF2L-FALSEAluSzSINE,Alu
chr116889044TA0.00256NBPF1-FALSE
chr5145666114GT0.00766RBM27+FALSE
chr1160112392GA0.00701ATP1A2+FALSEAluSx3SINE,Alu
chr344791547TC0.00184KIAA1143-TRUEAluJrSINE,Alu
chr629910583CT4.95604E-05.FALSE
chr116929327CT0.00304NBPF1-FALSEERVL-E-intSINE,Alu
chr1211918115CT0.00979LPGAT1-FALSEMER63DSINE,Alu
chr248602186AG0.00870FOXN2+FALSE
chr136068276TC0.00110PSMB2-TRUEAluScSINE,Alu
chr810689212CT3.39921E-05PINX1-FALSE
chr11650832AG0.00241CDK11B,CDK11A-FALSE
chr11001422GT0.00998.FALSELTR13ASINE,Alu
chr1180167090CT0.00607QSOX1+FALSE
chr49998493AG5.94150E-05SLC2A9-FALSE
chr1225684742TC0.00518ENAH-FALSE
chr19163502TC0.00366.FALSEAluSpSINE,Alu
chr2188330198CA0.00091TFPI-FALSEAluJbSINE,Alu
chr1450792966AT0.00852.FALSEAluSxSINE,Alu
chr16747231TG0.00269FBXL16-FALSE
chr1184761365AG0.00758FAM129A-FALSEAluJoSINE,Alu
chr1060047612AG0.00015CISD1+FALSE(A)nSINE,Alu
chr6105546950TC0.00443BVES-TRUEAluJbSINE,Alu
chr18045340CA0.00056PARK7+FALSE
chr127202982TC0.00850.FALSEAluSq2SINE,Alu
chr5180262080AG0.00259LINC00847+TRUEMLT2B3SINE,Alu
chr1145511983AG0.00596NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr133139061TC0.00079RBBP4+FALSEAluSx3SINE,Alu
chr110520725TC0.00795DFFA-TRUEAluSc8SINE,Alu
chr1145283718GA0.00989NBPF20,NOTCH2NL+FALSE
chr1228675570GC0.00298RNF187+FALSE
chr356763316GA0.00830ARHGEF3-FALSE
chr193603188AG0.00374MTF2+FALSE
chr11677253TC0.00145SLC35E2-FALSE
chr2174090630CA0.00025ZAK,MLK7-AS1+,-FALSE
chr76501833AT0.00937KDELR2-FALSE
chr1148556087GC0.00486.FALSE
chr2128620438CA0.00230AMMECR1L-FALSE
chr2217366901AG0.00143.FALSEAluSz6SINE,Alu
chr128939803CT1.27013E-09TAF12-FALSE
chr342636141GA0.00224SEC22C,SS18L2+,-FALSE
chr145244414TA0.00456.FALSE
chr128861636GA0.00754RCC1+FALSE(GCATGT)nSINE,Alu
chr1201846617AC0.00380IPO9+FALSE(CA)nSINE,Alu
chr3197611106AG0.00137.FALSEAluSx1SINE,Alu
chr2010036845AG0.00110SNAP25-AS1,ANKEF1+,-FALSE
chr5126889370CT0.00713PRRC1+FALSE
chr1244219904TG0.00482ZBTB18+FALSE
chr1179042550AG0.00831FAM20B+TRUEAluSx1SINE,Alu
chr1142804438GT0.00522.FALSE
chr3150262002GT0.00016SERP1-FALSE
chr729961939GT1.47033E-05SCRN1-FALSE
chr35257975AT9.78592E-05EDEM1+FALSE
chr1160967857TC0.00806F11R-TRUEAluSpSINE,Alu
chr1919791273AG0.00121ZNF101+TRUEAluSq2SINE,Alu
chr1680636297CG0.00161CDYL2-FALSE
chr1133694645TC2.61039E-05KIAA1549L+FALSE
chr12133297934AG9.03426E-06PGAM5+TRUEAluJoSINE,Alu
chr369038160GA0.00557EOGT-FALSE
chr837613106TC0.00626ERLIN2+FALSE
chr145280109AG0.00251.FALSEAluYk3SINE,Alu
chr115989141CG0.00677.FALSE
chr373431830AG0.00157PDZRN3-FALSE
chr1765334802TC1.10547E-05PSMD12-TRUEAluSqSINE,Alu
chr145244419TA0.00027.FALSE
chr16659505GA0.00196KLHL21-FALSE
chr129095757GT0.00739YTHDF2+FALSE
chr1919792288AG0.00379ZNF101+TRUEAluJbSINE,Alu
chr154692674AG0.00864SSBP3-FALSE
chr187379494AT0.00364SEP15-FALSE
chr417803616TC1.55934E-06DCAF16-TRUEAluYSINE,Alu
chr12125511311AG0.00299THRIL-FALSEAluSx1SINE,Alu
chr110520487TC0.00257.FALSEAluSx1SINE,Alu
chr210050947TC0.00273TAF1B+FALSE
chr310192596AG7.92003E-05VHL+TRUEAluSx1SINE,Alu
chr310193797AG0.00261VHL+TRUEAluSxSINE,Alu
chr2201774244TC0.00332.FALSEAluSzSINE,Alu
chr1145512950AG0.00996NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr19162933CT0.00088.FALSE
chr1109475635TC0.00458GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr132377391GA0.00439PTP4A2-FALSE
chr830536437TC0.00062GSR-FALSEAluSpSINE,Alu
chr136068210TC0.00178PSMB2-TRUEAluScSINE,Alu
chr237076498AC0.00797STRN-FALSE
chr1109746825AG0.00281KIAA1324+TRUEAluJbSINE,Alu
chr132697109AG0.00015EIF3I+FALSEAluSpSINE,Alu
chr146075777AG0.00268NASP+TRUEAluSx4SINE,Alu
chr1156613632GA0.00187BCAN+FALSE
chr234080819AC0.00815LINC01317+FALSEMSTDSINE,Alu
chr12124146569AG0.00013GTF2H3+TRUEAluSq2SINE,Alu
chr1015120306TC0.00323ACBD7-TRUEL1PA7SINE,Alu
chr211674374AG0.00559GREB1+FALSETigger9bSINE,Alu
chr138002068CT0.00962SNIP1-FALSE
chr1145512950AG2.03454E-08NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr119542458TC1.01966E-05LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1205683407TA0.00034NUCKS1-FALSE
chr275888160AC0.00599MRPL19+FALSEL1MB4SINE,Alu
chr3188603007CG0.00785LPP+FALSE
chr9116022896TC9.26547E-05SLC31A1+FALSE
chr399463810GT0.00496MIR548G,COL8A1+,-FALSE
chr159246520AC7.56706E-05JUN-FALSE
chr110517659TC0.00010.FALSEAluSx1SINE,Alu
chr122854931CA7.08508E-09ZBTB40+FALSEA-richSINE,Alu
chr777409288AG7.47972E-05.FALSEAluScSINE,Alu
chr674303531TC0.00487SLC17A5-TRUEAluJrSINE,Alu
chr254888359AG3.08576E-05SPTBN1+FALSE
chr3194789663TC0.00754XXYLT1-FALSEMARNASINE,Alu
chr6149915565AG0.00198RPS18P9+FALSE
chr133148284AG0.00793SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1144606838AG0.00988NBPF20+FALSE
chr159142713TC0.00246MYSM1-FALSE
chr128060574AG0.00206FAM76A+FALSE
chr194982784TA0.00179ABCD3+FALSE
chr232532809AG0.00255.FALSEAluSx1SINE,Alu
chr2176791250TC0.00078LNPK-TRUEMSTDSINE,Alu
chr1109479978GT0.00057CLCC1-FALSE
chr131905887AC0.00245SERINC2+FALSE
chr848889672AG0.00091MCM4+TRUEAluSx3SINE,Alu
chr140229368AG0.00154BMP8B,PPIE+,-FALSE
chr1811852628CT0.00048GNAL,CHMP1B+FALSE
chr5118174745TC0.00084DTWD2-TRUEAluYSINE,Alu
chr6107113953CG0.00300QRSL1+FALSEAluSgSINE,Alu
chr720178420TC0.00053MACC1,LOC101927668-TRUEAluYSINE,Alu
chr1176733946AG0.00725ACER3+FALSEA-richSINE,Alu
chr1475202857AG2.23354E-05FCF1+TRUEAluSxSINE,Alu
chr16259025CT0.00700RPL22-FALSE
chr1339598616GA2.18804E-06PROSER1-FALSE
chr1214524576TC0.00337PTPN14-TRUEAluSgSINE,Alu
chr13545183AT0.00347TPRG1L+FALSE
chr1667715890TC9.92672E-05GFOD2-TRUEAluJrSINE,Alu
chr349315592TC0.00127USP4-FALSE
chr1120165038AG0.00926ZNF697-FALSE
chr135648711AC0.00377SFPQ-FALSE
chr3160213318TG0.00215KPNA4-FALSE
chr123847464CA0.00895E2F2-FALSE
chr132739982GA0.00300LCK+FALSE
chr2239069181TC0.00346CBY1+FALSE
chr232535747AG0.00250.FALSEAluJbSINE,Alu
chr110044137AG2.83529E-05NMNAT1+TRUEAluSx1SINE,Alu
chr3184429718AG0.00914MAGEF1-FALSE
chr19160900TC0.00542.FALSEAluJbSINE,Alu
chr10120801785TA0.00665EIF3A-FALSE
chrX123045405AG0.00551XIAP+TRUEAluJoSINE,Alu
chr3183476685GA0.00032YEATS2+FALSE
chr126755494AG0.00874LIN28A+TRUEAluScSINE,Alu
chr185785548CT0.00353DDAH1-FALSE
chr1148251083TC0.00041NBPF8,NBPF14,NBPF9-FALSEL1MC4SINE,Alu
chr357612314TC0.00529DENND6A,PDE12+,-FALSEAluSpSINE,Alu
chr1145282799GA0.00081NBPF20,NOTCH2NL+FALSE
chr16160958AG0.00967KCNAB2+FALSE
chr140219065CT0.00232PPIE+FALSE
chr422404391GA0.00338ADGRA3-FALSE
chr444176960TC0.00043KCTD8-FALSE
chr112677547GA0.00015DHRS3-FALSE(A)nSINE,Alu
chr173512398TC0.00709SHPK,TRPV1-TRUEAluSxSINE,Alu
chr349506286GT0.00052DAG1+FALSEAluJbSINE,Alu
chr18938276TA0.00178ENO1-FALSE
chr237333930TC0.00073EIF2AK2-FALSEAluSzSINE,Alu
chr4177249593TG0.00038SPCS3+FALSE(T)nSINE,Alu
chr110519932TC5.00916E-05.FALSEAluJrSINE,Alu
chr581571875AT0.00072RPS23-FALSE
chr799636950AG0.00927ZKSCAN1+FALSEAluSx1SINE,Alu
chr39848222AT0.00083ARPC4,ARPC4-TTLL3+FALSE
chr353265766CT0.00088TKT-FALSE
chr322424406AT0.00760.FALSE
chr132687473TG0.00892TMEM234,EIF3I+,-FALSE
chr154692334TC5.22151E-05SSBP3-FALSE(T)nSINE,Alu
chr1180855948GA0.00218XPR1+FALSE
chr175171751TC0.00563CRYZ-FALSE
chr1399056476AT0.00535FARP1+FALSE
chr1176733943AG0.00925ACER3+FALSEA-richSINE,Alu
chr2217366866AG0.00247.FALSEAluSz6SINE,Alu
chr272968438GT0.00147EXOC6B-FALSE
chr120978304TA0.00018PINK1-AS,DDOST-FALSEAluYSINE,Alu
chr1117644949CG0.00862TTF2+FALSE
chr131532379AG0.00092PUM1-FALSE
chr29629298GC0.00590ADAM17-FALSE(TGT)nSINE,Alu
chr119542301TC0.00032LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr147746678GC0.00328STIL-FALSE
chr237327589TC0.00253.FALSE
chr237327662TC0.00220.FALSE
chr362189314CT0.00018PTPRG+FALSE
chr174672474GA0.00014FPGT-TNNI3K,FPGT+FALSEX12_DNASINE,Alu
chr226616356AG0.00030EPT1+FALSE
chr270316226AC0.00426PCBP1+FALSE
chr1121133995GC0.00575SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr110519888TC0.00878.FALSEAluJrSINE,Alu
chr1100440553AG0.00179SLC35A3+TRUEAluJbSINE,Alu
chr127202845TC0.00034.FALSEAluSq2SINE,Alu
chr1144594232CT2.29859E-05NBPF20+FALSE
chr112677525GA0.00122DHRS3-FALSE(A)nSINE,Alu
chr7128293103AC0.00313LINC01000+FALSE
chr373025345AG0.00219.FALSEAluSzSINE,Alu
chr110518733TC0.00399.FALSEAluSx1SINE,Alu
chr170696395AT0.00364SRSF11+FALSE
chr11593750AG0.00191CDK11B,SLC35E2B-FALSE
chr3172115590AG0.00355FNDC3B+FALSE
chr11597423CT1.10134E-13CDK11B,SLC35E2B-FALSE
chr133148196AG0.00303SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr119542433TC0.00076LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr744841236GA0.00819PPIA+FALSE
chr76442891GA0.00134RAC1+FALSE
chr286947783CT0.00515RNF103-CHMP3,RMND5A+,-FALSE
chr123833607AT0.00818E2F2-FALSE
chr3122283289CA0.00072DTX3L,PARP9+,-FALSE
chr154493197TC0.00064TMEM59-TRUEAluSz6SINE,Alu
chr1114939633GA0.00188TRIM33-FALSE
chr4144475125TG0.00133SMARCA5+FALSE
chr568858545CG0.00268GTF2H2C,GTF2H2C_2+FALSEAluSzSINE,Alu
chr439460539GA0.00323RPL9-FALSE
chr1450792961GA0.00547.FALSEAluSxSINE,Alu
chr1180144485GA0.00665QSOX1+FALSE
chr23597974TC1.93309E-05RNASEH1-FALSE
chr1154321623GA0.00782ATP8B2+FALSE
chr1206581246TC0.00210SRGAP2+FALSE
chr1204524400AG0.00029MDM4+TRUEAluYSINE,Alu
chr3158320703CA0.00841MLF1+FALSE
chr12125511952AG0.00138THRIL-FALSEAluSx1SINE,Alu
chr146828653TA0.00920NSUN4+FALSE
chr136068295TC0.00393PSMB2-TRUEAluScSINE,Alu
chr42940347TC0.00466NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr7100031502CT0.00091MEPCE+FALSE
chr495588274GA0.00095PDLIM5+FALSE
chr115736752GA0.00170EFHD2+FALSE
chr2134729931AG0.00040IFNAR1+TRUEAluSg7SINE,Alu
chr1145282600AC0.00391NBPF20,NOTCH2NL+FALSEMER126SINE,Alu
chr1115249843GA0.00218NRAS-FALSE
chr1114455907GA0.00705DCLRE1B+FALSE
chr2201774279TC9.55391E-05.FALSEAluSzSINE,Alu
chr120826781CT0.00110MUL1-FALSE
chr120978457TC0.00036PINK1-AS,DDOST-TRUEAluYSINE,Alu
chr2170488325AG0.00698PPIG+FALSE
chr1118066724AT0.00979MAN1A2+FALSE
chr119543973TC0.00236LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr3160969268CT0.00835NMD3+FALSE
chr1164084160CT0.00895ESRRA,TRMT112+,-FALSE
chr439550085TC3.55103E-05UGDH-AS1,SMIM14+,-FALSEFLAM_CSINE,Alu
chr766421684TG0.00042TMEM248+FALSEAluJrSINE,Alu
chr1207943285AG0.00011CD46+TRUEAluSx1SINE,Alu
chr9115447580TC2.95057E-05INIP-TRUEAluJbSINE,Alu
chr128826118AG0.00341PHACTR4+TRUEAluJbSINE,Alu
chr1145689812AG0.00431NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr11667419AC0.00028SLC35E2-FALSEAluSgSINE,Alu
chr457326315AG0.00281PAICS+TRUEAluJrSINE,Alu

Differential Expression Gene Analysis