Dataset Overview
RBPPPIG
Knock-MethodshRNA
RBP FamilyNon-canonical_RBP
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR620HAA
PlatformHiSeq
Pubmed ID32252787

PPIG - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PPIG
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PPIG


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr291805816GA2.75786E-10.FALSE
chr1206579798TC0.00476SRGAP2+FALSE
chr2217366590AG0.00013.FALSEAluSzSINE,Alu
chr996438974CG0.00303PHF2+FALSE(CTCCAC)nSINE,Alu
chr2206987136TC0.00189.FALSEAluSxSINE,Alu
chr192976590GA0.00768EVI5-FALSE
chr388104162TC0.00106CGGBP1-FALSE
chr1138980GT0.00608LOC729737-FALSE
chr237328097TC0.00091.FALSE
chr153291434AG0.00545ZYG11B+TRUEAluJrSINE,Alu
chr1530781885CT0.00380.FALSE
chr101086810TA0.00245IDI2-AS1,IDI1+,-FALSE
chr1118409491AT0.00471GDAP2-FALSE(A)nSINE,Alu
chr16747230CG0.00269FBXL16-FALSE
chr1949468569GT0.00266FTL+FALSE
chr11595586TC0.00206CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr2206982257TC0.00023.FALSEAluSg7SINE,Alu
chr1918476232AG0.00189PGPEP1+TRUEAluJbSINE,Alu
chr6166824702CT0.00587RPS6KA2-FALSE(T)nSINE,Alu
chr517276088CA0.00171BASP1+FALSE(TC)nSINE,Alu
chr3122283293CG0.00071DTX3L,PARP9+,-FALSE
chr146125880TC0.00686GPBP1L1-FALSE
chr1121133995GC0.00575SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr11252180TC0.00021CPSF3L-TRUEAluSxSINE,Alu
chr129464350GC0.00209LOC642846+FALSE
chr1204374665GA0.00717PPP1R15B-FALSE
chr111298093CT1.54321E-14MTOR-FALSE
chr1583685469TC0.00976BTBD1-FALSE
chr129848629AG0.00027CLEC2D+FALSE
chr1280168993GT0.00513PPP1R12A-FALSE
chr1144917841TC4.47769E-05NBPF20,PDE4DIP+,-FALSE
chr1953914807AG4.44644E-06ZNF765+TRUEAluSpSINE,Alu
chr133148006AG0.00110SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr2220416942GC0.00100OBSL1-FALSE
chr15102512797AG0.00080WASH3P+FALSE
chr1231154921CT0.00773FAM89A-FALSE(T)nSINE,Alu
chr473923056TC0.00077COX18-TRUEAluSzSINE,Alu
chr110517653TC0.00776.FALSEAluSx1SINE,Alu
chr132827843GC0.00275FAM229A-FALSE
chr647594192CT0.00591CD2AP+FALSE
chr237331555TC0.00171.FALSEAluJbSINE,Alu
chr3122283289CA0.00072DTX3L,PARP9+,-FALSE
chr116892277GT0.00021NBPF1-FALSE
chr125570692CT0.00095RSRP1-FALSE
chr1179084080TG0.00926ABL2-FALSE
chr153288897AG0.00439ZYG11B+TRUEAluJoSINE,Alu
chr2178482698AG0.00408TTC30A-FALSE
chr540829980TC0.00752.FALSEAluSpSINE,Alu
chr1919792288AG0.00379ZNF101+TRUEAluJbSINE,Alu
chr1269159400GA0.00173SLC35E3+FALSE(AT)nSINE,Alu
chr89639522AG0.00823TNKS+TRUEMER53SINE,Alu
chr1749042289GT0.00737SPAG9-FALSEAluJbSINE,Alu
chr2025428669AG0.00023GINS1+TRUEAluJbSINE,Alu
chr358306638AG0.00988.FALSEAluSzSINE,Alu
chr3169810385CT0.00621PHC3-FALSE
chr11417974CT0.00677ATAD3B+FALSE
chr146078630AG0.00131NASP+FALSE
chr1681064656AG0.00120CENPN+TRUEAluSgSINE,Alu
chr3196557274CT0.00285PAK2+FALSE
chr1918477337AG0.00085PGPEP1+TRUEAluSx1SINE,Alu
chr1913884096AG0.00049MRI1+TRUEAluSzSINE,Alu
chr116889127AG0.00213NBPF1-FALSEL1MC4SINE,Alu
chr2160084473AC0.00101TANC1+FALSE
chr138279683AT0.00685MTF1-FALSE
chr1541590288GT0.00349OIP5-AS1+FALSE
chr125169634AG0.00531CLIC4+FALSE
chr1146647196TC0.00241.FALSETHE1DSINE,Alu
chr5176863519GC0.00567GRK6+FALSE
chr116932845TG0.00732NBPF1-FALSEL1MC2SINE,Alu
chr12123253723AG0.00371DENR+TRUE(AT)nSINE,Alu
chr1213069114CA0.00681FLVCR1+FALSE
chr1111969752AG0.00531OVGP1-FALSE
chr1160965379TC0.00477F11R-TRUEAluScSINE,Alu
chr1332973012AC0.00231BRCA2+FALSE
chr116892918TC0.00158NBPF1-FALSE
chr1298943187AG2.29648E-09TMPO+TRUEAluSzSINE,Alu
chr1109419841CT0.00057GPSM2+FALSE
chr3196557357GT0.00615PAK2+FALSE
chr110520532TC0.00142.FALSEAluSx1SINE,Alu
chr123408016CA4.80633E-05KDM1A+FALSE
chr143629982CT0.00733EBNA1BP2-FALSE
chr11337334GT0.00549LOC148413,MRPL20+,-FALSE
chr119543456TC0.00011LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1847918818AG3.50049E-05SKA1+TRUEAluJbSINE,Alu
chr1100549715TA0.00765SASS6-FALSE
chr5139931622TA0.00881SRA1-FALSE
chr141088377CT8.47840E-10RIMS3-FALSE
chr1541590932AG0.00055OIP5-AS1+TRUEAluSx1SINE,Alu
chr1450053348GA0.00067.FALSE7SLRNASINE,Alu
chr2113513825TC2.13681E-05CKAP2L-FALSE
chr11595048TC0.00495CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr1131452788AG0.00239DNAJC24+TRUEAluSx1SINE,Alu
chr1121115958TC0.00818SRGAP2-AS1,SRGAP2D,SRGAP2B,SRGAP2C+,-FALSE
chr1118503786AG0.00135SPAG17-FALSEAluSx3SINE,Alu
chr1179326296AG0.00171SOAT1+TRUE
chr23627302AT0.00021RPS7+FALSE
chr643582795AG0.00087POLH+TRUEAluSx1SINE,Alu
chr193603177TC0.00364MTF2+FALSE
chr636894337GA0.00607C6orf89+FALSEGA-richSINE,Alu
chr261369774TC0.00267LOC339803-TRUEAluSxSINE,Alu
chr116933625AG0.00536NBPF1-FALSEGA-richSINE,Alu
chr11337735TG3.46713E-05MRPL20-FALSE
chr477057501AG0.00547NUP54-FALSE
chr5122165501AT0.00051SNX2+FALSE(AC)nSINE,Alu
chr1157043632CT0.00085.FALSE
chr5149363219AG0.00866SLC26A2+FALSEAluJrSINE,Alu
chr13548832GC0.00464WRAP73-FALSE
chr229170763GA5.21672E-05WDR43+FALSE
chr3129286413GC2.51503E-06PLXND1-FALSE
chr110517689TC0.00504.FALSEAluSx1SINE,Alu
chr116932144AC0.00559NBPF1-FALSE
chr811700444CG0.00042CTSB-FALSEAluSq2SINE,Alu
chr1144595886GA0.00242NBPF20+FALSEAluJbSINE,Alu
chr362189465CT2.69664E-05PTPRG+FALSE
chr119542239TC0.00043LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1110173775GT0.00038AMPD2+FALSE
chr128921019AG0.00030RAB42+TRUEAluSxSINE,Alu
chr315114395TC0.00333RBSN-TRUEAluYSINE,Alu
chr1179326879AG0.00232SOAT1+TRUEAluJoSINE,Alu
chr298409998GT0.00261TMEM131-FALSE
chr1179811936TC0.00229TOR1AIP2-FALSEAluYSINE,Alu
chr9130268408TC6.51633E-05FAM129B-FALSE(CTCA)nSINE,Alu
chr310192784AG1.73909E-05VHL+TRUEAluSx1SINE,Alu
chr1160231910AT0.00051DCAF8-FALSE
chr14103372464CA0.00577TRAF3+FALSE(AC)nSINE,Alu
chr19161245TC0.00071.FALSEAluSxSINE,Alu
chr2206858904CT0.00783INO80D-FALSE
chr848890109AG0.00750MCM4+TRUEAluJbSINE,Alu
chr1226171340TC0.00462SDE2-TRUEBC200SINE,Alu
chr756079033TC0.00300PSPH-TRUEAluYm1SINE,Alu
chr856985609GT0.00134RPS20-FALSE
chr1246831356GA0.00616CNST+FALSE
chr124286327GA0.00053PNRC2+FALSE
chr2103333653TC0.00426MFSD9-FALSEAluYm1SINE,Alu
chr5180682611CA9.20591E-05CTC-338M12.4+FALSE
chr417804740TC0.00015DCAF16-TRUEAluSxSINE,Alu
chr67289958CG0.00893SSR1-FALSE
chr121102502CA0.00021HP1BP3-FALSE
chr124288535AT0.00271PNRC2+FALSE
chr3195963500CT0.00014.FALSE
chr398307696TG3.25383E-09CPOX-FALSE
chr543574976TC0.00613NNT-AS1-TRUEAluSq2SINE,Alu
chr333138549GA0.00612GLB1-FALSE
chr1117117182CT0.00270IGSF3-FALSE
chr5125961534AG0.00233PHAX+TRUEAluSz6SINE,Alu
chr1109181304CA0.00592FAM102B+FALSE
chr1183486859GA0.00831SMG7+FALSE
chr2234203547TC0.00476ATG16L1+FALSE
chr1180854783TC0.00292XPR1+FALSE
chr11018144TC0.00019C1orf159-FALSE
chr132799530CA8.96009E-06MARCKSL1-FALSE
chr611577085CT1.34362E-05TMEM170B+FALSE
chr1396506664AG5.36176E-05UGGT2-FALSE
chr146076468AG0.00069NASP+TRUEAluSxSINE,Alu
chr1241794056CA0.00753OPN3,CHML-FALSE
chr2178084651AG1.09207E-09HNRNPA3+FALSE
chr4123816376AT0.00445FGF2,NUDT6+,-FALSE
chr145120664CT0.00437TMEM53-FALSE
chr110043053AG0.00042NMNAT1+TRUEAluScSINE,Alu
chr12133297956AG4.23080E-06PGAM5+TRUEAluJoSINE,Alu
chr2176042866AT0.00596ATP5G3-FALSE
chr1143399383TA0.00053.FALSEL1MC4SINE,Alu
chr136067833TC3.75622E-05PSMB2-TRUEAluSzSINE,Alu
chr2231375020TA0.00990TUG1+FALSE
chr12120898554AG0.00124GATC+TRUEAluYSINE,Alu
chr1118068558GA0.00644.FALSE
chr11683565GA7.19943E-05NADK-FALSE
chr1819445881TA0.00224MIB1+FALSE
chr153288974AT0.00265ZYG11B+FALSEAluJoSINE,Alu
chr1100654769TC0.00318DBT-TRUEAluSzSINE,Alu
chr127248275CT0.00047NUDC+FALSE
chr140219065CT0.00232PPIE+FALSE
chr1113212974AT0.00424CAPZA1+FALSE
chr145975286AG0.00200MMACHC+TRUEAluSg7SINE,Alu
chr110519947TC0.00323.FALSEAluJrSINE,Alu
chr2206985727CT0.00786.FALSEMIRcSINE,Alu
chr5149363214AG0.00040SLC26A2+TRUEAluJrSINE,Alu
chr1176176230GA0.00091RFWD2-FALSE
chr159122059GA0.00476MYSM1-FALSE
chr537290493TC3.58668E-05.FALSEAluSzSINE,Alu
chr744917281TC0.00222PURB-TRUEAluSzSINE,Alu
chr1179042551AG0.00336FAM20B+TRUEAluSx1SINE,Alu
chr3181430334GA0.00305SOX2-OT,SOX2+FALSE
chr1247319707CT3.10675E-05ZNF124-FALSE
chr5149829072GT0.00816RPS14-FALSE
chr3197362030CT0.00302.FALSE
chr173561396CT0.00322CTNS+FALSE
chr133148118AG0.00374SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1061549818AG0.00879CCDC6-FALSE
chr1227953264AT0.00688KLHL42+FALSE
chr16282401TC0.00806ICMT-TRUEAluSzSINE,Alu
chr1860998527CG0.00078KDSR-FALSE(AGAGAGAC)nSINE,Alu
chr1753239140CT0.00954STXBP4+FALSEMIRSINE,Alu
chr1100656265CT0.00318DBT-FALSE
chr5157185319AG0.00100LSM11+TRUEAluSqSINE,Alu
chr3196080528TC0.00700UBXN7-TRUEAluSxSINE,Alu
chr4113198883GT0.00905TIFA-FALSE
chr1154554946CG0.00488ADAR-FALSE
chr1900719TA0.00436KLHL17+FALSE(TTTA)nSINE,Alu
chr145975584TC0.00327MMACHC+FALSEAluSx4SINE,Alu
chr16282324TC0.00142ICMT-TRUEAluSzSINE,Alu
chr11252248AG0.00503CPSF3L-FALSEAluSxSINE,Alu
chr786816663AG0.00103DMTF1+TRUEAluJrSINE,Alu
chr426433556AC3.10862E-15RBPJ+FALSE
chr119542464TC0.00140LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1155695985AG0.00031DAP3+TRUEAluSpSINE,Alu
chr1610625108TC7.88488E-10EMP2-TRUEAluSx3SINE,Alu
chr128825337AG0.00099PHACTR4+TRUEAluSgSINE,Alu
chr5122359498AC0.00362PPIC-FALSE(AC)nSINE,Alu
chr199164434GA0.00309SNX7+FALSE
chr1149885583AG0.00030SV2A-FALSE
chr255516908AG0.00016CCDC88A-FALSE(GA)nSINE,Alu
chr1742877584TC0.00489GJC1-TRUEAluSgSINE,Alu
chr57878179CT0.00014MTRR+FALSE
chr729960462GA5.89775E-06SCRN1-FALSE
chr3148748197TA0.00026HLTF-FALSE
chr19330479CT0.00352H6PD+FALSE
chr2242512138AG9.62871E-05BOK+FALSE
chr116889502TC0.00516NBPF1-TRUEL1MC4SINE,Alu
chr7100957851TC0.00028LOC101927746,IFT22+,-FALSEMADE1SINE,Alu
chr1631469051TC0.00278.FALSEAluSzSINE,Alu

Differential Expression Gene Analysis