Dataset Overview
RBPSUB1
Knock-MethodshRNA
RBP FamilyPC4
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR997FOT
PlatformHiSeq
Pubmed ID32252787

SUB1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of SUB1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of SUB1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1108113839TC0.00027VAV3-FALSE
chr344791398TC0.00204KIAA1143-TRUEAluJrSINE,Alu
chr1648386442AG0.00964LONP2,MIR5095+TRUEAluSz6SINE,Alu
chr3121351277AT0.00388HCLS1-FALSE
chr19643028AG0.00017.FALSEAluSxSINE,Alu
chr2127826533AG0.00104BIN1-FALSE
chr3178954055TC0.00308PIK3CA+FALSE
chr144088568GA0.00274PTPRF+FALSEA-richSINE,Alu
chr238971637GA2.13337E-05SRSF7-FALSE
chr2178406768TA0.00416AGPS+FALSE
chr155316322AG0.00172DHCR24-FALSE
chr133086876TC0.00075ZBTB8OS-TRUEAluYSINE,Alu
chr154571374AG0.00280TCEANC2+TRUEAluScSINE,Alu
chr128824041TA0.00872PHACTR4+FALSEAluSxSINE,Alu
chr1585185045TC0.00210WDR73,SCAND2P+,-FALSEAluSzSINE,Alu
chr12336210CT0.00206RER1+FALSE
chr1063829539CT0.00918ARID5B+FALSE
chr5140720886AG0.00980PCDHGA1,PCDHGA2+FALSE
chr366024384GC0.00096MAGI1-FALSE
chr1648387215AG0.00864LONP2,MIR5095+TRUEAluJbSINE,Alu
chr345721891AG0.00163LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr27181560GA0.00599RNF144A+FALSE
chr159121768GC0.00196MYSM1-FALSE
chr2045839076AT0.00178ZMYND8-FALSE(T)nSINE,Alu
chr119543465TC0.00117LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1953155674TC1.27993E-05ZNF83-TRUEAluSgSINE,Alu
chr1205686523GT2.43057E-05NUCKS1-FALSE
chr1145369709AG0.00258NBPF20,NBPF10+TRUEL1MC4SINE,Alu
chr120811795GC0.00047CAMK2N1-FALSE
chr138002251GC0.00624SNIP1-FALSE
chr116890639CT5.60894E-05NBPF1-FALSE
chr1109605648AG0.00033.FALSEAluYSINE,Alu
chr153289940AG0.00245ZYG11B+TRUEFRAMSINE,Alu
chr2018468339TC0.00062RBBP9-TRUEAluSz6SINE,Alu
chr1182353198AT0.00985GLUL-FALSE
chr189649462TC2.70922E-05GBP4-TRUEAluJbSINE,Alu
chr136068052GT1.69686E-12PSMB2-FALSEL1ME4bSINE,Alu
chr644417159AG0.00959CDC5L+TRUEFLAM_CSINE,Alu
chr236704034AG9.89157E-05CRIM1+FALSE
chr1110201699TC0.00513GSTM4+FALSE
chr2113334241AG0.00388POLR1B+TRUE
chr186817074GT9.65311E-06ODF2L-FALSEL1PA7SINE,Alu
chr1475202402AG0.00141FCF1+TRUEAluScSINE,Alu
chr3176739663AG5.46505E-07TBL1XR1-FALSE
chr1475202373AG0.00019FCF1+FALSEAluScSINE,Alu
chr1128134974CA0.00479METTL15+FALSE
chr114113455GA0.00647PRDM2+FALSE
chr2217366196TA0.00207.FALSE
chr145987539CA0.00660PRDX1-FALSE
chr1776799795GA0.00363USP36-FALSE
chr1168218522AG0.00153.FALSEAluSzSINE,Alu
chr19162223TC0.00997.FALSEAluSxSINE,Alu
chr1179327008AG0.00168SOAT1+TRUE
chr1051613297AG0.00347TIMM23B,TIMM23+,-FALSE
chr2216908679CT0.00988PECR-FALSE
chr122852880GC0.00247ZBTB40+FALSE
chr1205738302GA0.00247RAB29-FALSE
chr3197612334AG0.00070.FALSEAluSpSINE,Alu
chrX123045407AG0.00153XIAP+TRUEAluJoSINE,Alu
chr42940147TC0.00036NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr229135468CG0.00262WDR43+FALSE
chr1148753329AG7.42327E-05.FALSE
chr140219280TC8.82951E-05PPIE+FALSE
chr1490509582TC0.00017TDP1+FALSE
chr2216148871TG0.00071.FALSETigger1SINE,Alu
chr347628808AT0.00792SMARCC1-FALSE
chr136067760TC0.00024PSMB2-TRUEAluSzSINE,Alu
chr127107650TA3.71504E-05ARID1A+FALSE
chr1229652587TC0.00732ABCB10-FALSE
chr1114940228CT0.00734TRIM33-FALSE(T)nSINE,Alu
chr1109865630CT0.00647SORT1-FALSE
chr540832557GT5.89786E-05RPL37-FALSE
chr2128060859TA0.00016MAP3K2-FALSE
chr193121451CT0.00567GNA11+FALSE
chr13545194CG0.00044TPRG1L+FALSE
chr1773702478GC8.31704E-05SAP30BP+FALSE
chr116891365GA1.42078E-05NBPF1-FALSE
chr2203741602TC0.00581.FALSEAluJrSINE,Alu
chr3176739694TC1.91391E-08TBL1XR1-FALSE
chr314986447TC2.03372E-08FGD5-AS1-TRUEAluSq2SINE,Alu
chr110521172TC0.00244DFFA-TRUEAluYSINE,Alu
chr1013320126TA0.00830PHYH-FALSE
chr145671434GC0.00819ZSWIM5-FALSE
chr5125962175AG0.00020PHAX+TRUEAluScSINE,Alu
chr1942376710AG1.82395E-05.FALSEAluSpSINE,Alu
chr1942376675AG0.00085.FALSE
chr1725640011AG0.00228WSB1+TRUEAluSxSINE,Alu
chr115904318CT0.00109AGMAT-FALSE
chr1114306369AT0.00834RSBN1-FALSE
chr342826041TG0.00019HIGD1A-FALSE
chr237330506TC0.00140.FALSEAluSq2SINE,Alu
chr1179044100AG0.00487FAM20B+TRUEAluSxSINE,Alu
chr2234183368AG0.00369ATG16L1+FALSE
chr2172413267GC0.00938CYBRD1+FALSE
chr2217366674AG0.00219.FALSEAluSzSINE,Alu
chr1089005496TG0.00138NUTM2A-AS1-FALSEMSTB1SINE,Alu
chr133149495AG0.00675SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr4113198883GT0.00905TIFA-FALSE
chr146075171AC0.00280NASP+FALSEA-richSINE,Alu
chr110517564TC0.00371.FALSEAluSx1SINE,Alu
chr126802457CA0.00962HMGN2+FALSE
chr1157963370CG0.00445KIRREL+FALSE
chr1144053664AC0.00050.FALSE
chr194351063AT0.00907GCLM-FALSE
chr1100203693GA0.00142FRRS1-FALSE
chr1681064534AG0.00480CENPN+TRUEAluSgSINE,Alu
chr540832553AT0.00121RPL37-FALSE
chr1231377081CT6.17358E-06GNPAT+FALSE
chr1210025751GA0.00067DIEXF+FALSETigger4aSINE,Alu
chr644222158TA0.00781SLC35B2-FALSE
chr274333235CT0.00022TET3+FALSE
chr1201438095CG3.49736E-05PHLDA3-FALSE
chr116912029CG0.00177NBPF1-FALSE
chr1214524178TC0.00265PTPN14-TRUEAluSxSINE,Alu
chr116952481AG0.00093CROCCP2-FALSE
chr642048128GT0.00604TAF8+FALSEAluSq2SINE,Alu
chr764435678TA0.00256ZNF117-FALSE
chr1765335459TC5.16289E-08PSMD12-TRUEAluSxSINE,Alu
chr5149823795AT0.00261RPS14-FALSE
chr4144442611TC0.00899SMARCA5+FALSE
chr1350102992TC0.00956SETDB2-PHF11,PHF11+FALSEL2aSINE,Alu
chr15102516512GA0.00041WASH3P+FALSE
chr9125609943AG0.00247.FALSE
chr3141667460TG0.00193TFDP2-FALSE
chr744918732TC0.00039PURB-FALSEAluSgSINE,Alu
chr349395695AC0.00159GPX1-FALSE
chr2113287200CT0.00087TTL+FALSE(T)nSINE,Alu
chr1144851999AC0.00385NBPF20,PDE4DIP+,-FALSE
chr1179044206AG0.00458FAM20B+TRUEAluSxSINE,Alu
chr193803490TC0.00572CCDC18-AS1-FALSEAluJrSINE,Alu
chr116921146TC0.00382NBPF1-FALSE
chr120976174TC0.00103PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr11647814TC0.00123CDK11B,CDK11A-FALSE
chr41228741GA0.00095CTBP1-FALSE
chr7115898258AT0.00314TES+FALSE(T)nSINE,Alu
chr5179720333AG0.00308.FALSE
chr1225358969TG0.00965KRAS-FALSE
chr12133297961AG1.06136E-06PGAM5+TRUEAluJoSINE,Alu
chr1114443474AG9.14620E-06AP4B1-AS1,AP4B1+,-FALSEAluSpSINE,Alu
chr1145322843CT0.00271NBPF20,NBPF10+FALSE
chr439550085TC3.55103E-05UGDH-AS1,SMIM14+,-FALSEFLAM_CSINE,Alu
chr456282224AG0.00485TMEM165+TRUEAluJbSINE,Alu
chr1475202287TC0.00757FCF1+FALSEAluScSINE,Alu
chr5134302899AG0.00025.FALSEAluSq2SINE,Alu
chr3196556843GA4.00732E-06PAK2+FALSE
chr1235392546TC0.00312ARID4B-FALSE
chr7100804140CT0.00377AP1S1+FALSE
chr823087535AG0.00491LOC389641+FALSEAluSx1SINE,Alu
chr167518534CT0.00030SLC35D1-FALSE
chr143272842AT5.86577E-06SVBP-FALSE
chr1109967951AC0.00095PSMA5-FALSE
chr299772827AG0.00108LIPT1+TRUEAluSx1SINE,Alu
chr5140482871TG0.00650PCDHB3+FALSE
chr119653870TC0.00477PQLC2+FALSE
chr2191556844TC0.00024NAB1+FALSE
chr454244053GC0.00726FIP1L1+FALSE(CGGAG)nSINE,Alu
chr29558812GT0.00427ITGB1BP1-FALSE
chr133147722GA1.17176E-11SYNC,RBBP4+,-FALSE
chr11252749TC0.00875CPSF3L-TRUEAluSpSINE,Alu
chr232532849AG0.00909.FALSEAluSx1SINE,Alu
chr138002068CT0.00962SNIP1-FALSE
chrX123045381AG0.00893XIAP+TRUEAluJoSINE,Alu
chr1118502757GA0.00793WDR3,SPAG17+,-FALSE(GT)nSINE,Alu
chr121602602AG8.31525E-05ERC1+FALSEAluSxSINE,Alu
chr72294401AG0.00035SNX8-FALSE
chr1145369550AG0.00031NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr641900765AG0.00256BYSL+FALSE
chr386991598GT0.00179VGLL3-FALSE
chr1298943103AG0.00528TMPO+TRUEAluSzSINE,Alu
chr674133990TC0.00201.FALSEAluYSINE,Alu
chr7100072031TC0.00238TSC22D4-FALSE
chr457326291AG0.00017PAICS+TRUEAluJrSINE,Alu
chr20309186AG0.00665SOX12+FALSEA-richSINE,Alu
chr121085978TA0.00421RAD52-FALSEL2SINE,Alu
chr7156764972GA0.00871NOM1+FALSE
chr1194606941TC0.00699AMOTL1+FALSE
chr1681064492AG0.00935CENPN+TRUEAluSgSINE,Alu
chr59546451GA0.00030SNHG18+FALSE
chr1144828795CG0.00887NBPF20,NBPF9+FALSE
chr220449068AG0.00014PUM2-FALSE
chr3160286646CT0.00086.FALSE
chr1923542157TC0.00140ZNF91-TRUEAluYSINE,Alu
chr11252443TC8.33820E-06CPSF3L-TRUEAluJrSINE,Alu
chr366419942AG0.00284SLC25A26+FALSE
chr1179044169AG0.00039FAM20B+TRUEAluSxSINE,Alu
chr5125961455AG0.00029PHAX+TRUEAluSz6SINE,Alu
chr1115259768TC0.00156CSDE1-FALSE
chr1179876988CG0.00045TOR1AIP1+FALSE
chr111347152AT0.00401UBIAD1+FALSE
chr643582750AG0.00844POLH+TRUEAluSx1SINE,Alu
chr110520684TC0.00842DFFA-TRUEAluSc8SINE,Alu
chr3184766301TC0.00025VPS8+FALSE
chr178414329GA0.00874FUBP1-FALSEA-richSINE,Alu
chr937503490AG0.00612POLR1E+TRUEAluJbSINE,Alu
chr1160967816TC0.00162F11R-TRUEAluSpSINE,Alu
chr1212254067GA0.00714DTL+FALSE
chr5126889370CT0.00713PRRC1+FALSE
chr1114515717GA0.00018HIPK1+FALSE
chr146075612AG0.00153NASP+TRUEAluSx4SINE,Alu
chr128661657AG0.00910MED18+TRUEAluSgSINE,Alu
chr224225542AG0.00348.FALSEAluSq2SINE,Alu
chr1959095573AG0.00169CENPBD1P1+TRUEAluJbSINE,Alu
chr1749042216TC0.00746SPAG9-TRUEAluJbSINE,Alu
chr399517483CT0.00070MIR548G-FALSE(TG)nSINE,Alu
chr136770605CT8.58098E-05THRAP3+FALSE(T)nSINE,Alu
chr21636053AG0.00189PXDN-FALSE
chr378646942TG0.00093ROBO1-FALSE
chr116890130AC0.00728NBPF1-FALSE
chr631132911CT0.00000.FALSE
chr187811103TG0.00028LMO4+FALSE
chr4185549875AT0.00616CASP3-FALSE
chr247604176CT0.00328EPCAM+FALSE
chr3113604709TC0.00012GRAMD1C+FALSE
chr261405795GT0.00061AHSA2+FALSE
chr1913054905TC0.00324CALR+FALSE(T)nSINE,Alu
chr2105883650TG0.00086TGFBRAP1-FALSE
chr190401562CA0.00057LRRC8D+FALSE
chr1201845903AG0.00041IPO9+FALSE
chr1469708241GA0.00748EXD2+FALSE
chr1116234083TA0.00477VANGL1+FALSE
chr191981317TA0.00539CSNK1G2+FALSE
chr2234749258TC0.00710HJURP-FALSE
chr153290298AG0.00063ZYG11B+TRUEAluSg4SINE,Alu
chrX133930368TG0.00126FAM122B-FALSEG-richSINE,Alu
chr128662182AG0.00402MED18+TRUEAluSq2SINE,Alu
chr1075009585TC2.45347E-10DNAJC9-AS1,MRPS16+,-FALSEAluScSINE,Alu
chr310193797AG0.00199VHL+TRUEAluSxSINE,Alu
chr19161090AG0.00068.FALSEAluJbSINE,Alu
chr3196080531TC0.00952UBXN7-TRUEAluSxSINE,Alu
chr116929100CT0.00249NBPF1-FALSELTR16B2SINE,Alu
chr116929327CT0.00315NBPF1-FALSEERVL-E-intSINE,Alu
chr791742141TA0.00620CYP51A1-FALSEAluSx3SINE,Alu
chr1197093361GA8.55632E-06ASPM-FALSE
chr2219460472TC0.00187CNOT9+FALSE
chr3124950421TA0.00713ZNF148-FALSE
chr230748507CT0.00103LCLAT1+FALSE
chr1109818158CT0.00628CELSR2+FALSE
chr2232574807CG0.00134PTMA+FALSE
chr1150704483TC0.00028CTSS-TRUEAluJoSINE,Alu
chr237331065TC0.00017.FALSEAluSx1SINE,Alu
chr189851328AG0.00028GBP6+FALSEAluSzSINE,Alu
chr2025427756AG0.00396GINS1+TRUEAluSzSINE,Alu
chr3122293773AT0.00147DTX3L+FALSE
chr2132481508CG0.00093C2orf27A+FALSE
chr1475202412AG5.03546E-10FCF1+TRUEAluScSINE,Alu
chr1910795968CT0.00700ILF3+FALSE
chr132801745AG0.00357MARCKSL1-FALSE
chr2191556849AT0.00158NAB1+FALSE
chr720177519TC0.00885MACC1,LOC101927668-TRUEAluSxSINE,Alu
chr1149943157GA0.00024OTUD7B-FALSE
chr1235715523AG0.00660GNG4-FALSE
chr115909744CT0.00100AGMAT-FALSE
chr2206983491TC0.00505.FALSEAluSxSINE,Alu

Differential Expression Gene Analysis