Dataset Overview
RBPSAFB2
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR770LYW
PlatformHiSeq
Pubmed ID32252787

SAFB2 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of SAFB2
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of SAFB2


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr2201774775TC0.00872.FALSEAluJr4SINE,Alu
chr112628188TC6.05765E-06DHRS3-FALSE
chr119585545GA0.00696MRTO4+FALSEAluSc8SINE,Alu
chr116895634TG0.00472NBPF1-FALSE
chr255516902GA0.00011CCDC88A-FALSE(GA)nSINE,Alu
chr417633798AG0.00053FAM184B-FALSEAluSzSINE,Alu
chr128836974AG9.88453E-07SNHG3,RCC1+TRUEAluScSINE,Alu
chr1743364288AG0.00345MAP3K14-FALSE
chr5126889370CT0.00713PRRC1+FALSE
chr19160963TC0.00098.FALSEAluJbSINE,Alu
chr120976023TC1.28334E-05PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr561683960AG0.00491.FALSE
chr830643549GC0.00257PPP2CB-FALSE
chr1144595935GA0.00860NBPF20+FALSEAluJbSINE,Alu
chr636894341GA0.00575C6orf89+FALSEGA-richSINE,Alu
chr145280500AG0.00857.FALSEAluSxSINE,Alu
chr1117078729AG0.00983CD58-FALSE
chr1160967899TC0.00661F11R-TRUEAluSpSINE,Alu
chr452888499GA0.00366SGCB-FALSE
chr19642828TA0.00148SLC25A33+FALSE
chr453463566CT5.12751E-05USP46-FALSE
chr194352553CT0.00136GCLM-FALSEAluSx1SINE,Alu
chr1179326278AG0.00379SOAT1+TRUE
chr1075632760CT0.00013CAMK2G-FALSE
chr535064460GC0.00920PRLR-FALSE
chr11252349AG0.00798CPSF3L-FALSEAluJrSINE,Alu
chr1900720AT0.00711KLHL17+FALSE(TTTA)nSINE,Alu
chr1109746825AG0.00281KIAA1324+TRUEAluJbSINE,Alu
chr19165685GA7.66901E-05GPR157-FALSE
chr1165179819TC0.00038FRMD8+FALSE
chr237331275TC0.00884.FALSEAluSx1SINE,Alu
chr791630345GA0.00473AKAP9+FALSE
chr1150771703TC0.00500CTSK-FALSE
chr4124237124AG0.00119SPATA5+TRUEAluJrSINE,Alu
chr120978294TA0.00985PINK1-AS,DDOST-FALSE
chr268402794TG0.00630PNO1+FALSE
chr5177576460CT0.00635.FALSE
chr1475202722AG0.00022FCF1+TRUEAluScSINE,Alu
chr13371368CG0.00689ARHGEF16+FALSE
chr2103333654AT0.00488MFSD9-FALSEAluYm1SINE,Alu
chr1179326925CT0.00284SOAT1+FALSEAluJoSINE,Alu
chr3172115590AG0.00355FNDC3B+FALSE
chr7115898442GC2.36867E-05TES+FALSEAluSxSINE,Alu
chr237330476TC2.74271E-05.FALSEAluSq2SINE,Alu
chr145280426AG0.00802.FALSEAluSxSINE,Alu
chr145244432TA0.00154.FALSE
chr247562582GA0.00484LOC101927043-FALSEBC200SINE,Alu
chr63022544TC7.02821E-06HTATSF1P2-TRUEAluJrSINE,Alu
chr457327092AG0.00091PAICS+TRUEAluSx1SINE,Alu
chr1687440117CT1.93168E-06ZCCHC14-FALSE
chr110520331CT0.00527.FALSEAluSx1SINE,Alu
chr3183476685GA0.00032YEATS2+FALSE
chr12121118CT0.00234FAAP20-FALSE
chr116703162AT0.00726MRPL17-FALSE
chr3128339057AT0.00535RPN1-FALSE(A)nSINE,Alu
chr177759578AG0.00031AK5+FALSE
chr226477130TC0.00501HADHB+FALSE
chr3182614493TC0.00036ATP11B+FALSE
chr1148556087GC0.00486.FALSE
chr1114940246CA0.00628TRIM33-FALSE
chr121795388AG0.00732NBPF3+FALSE
chr830536152TC0.00015GSR-TRUEAluJrSINE,Alu
chr439550549TC0.00014UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr1179843781TC0.00888TOR1AIP2-TRUEAluJbSINE,Alu
chr1201845903AG0.00041IPO9+FALSE
chr1942375586AG0.00404.FALSEAluSxSINE,Alu
chr1453242425TC0.00473GNPNAT1-TRUEAluJoSINE,Alu
chr115909744CT0.00100AGMAT-FALSE
chr1013320111GT0.00571PHYH-FALSE
chr7128294489GT0.00354LINC01000+FALSE
chr1549454018CT0.00053GALK2+FALSEAluSx1SINE,Alu
chr119586520AG0.00659MRTO4+TRUEAluSzSINE,Alu
chr1160966434TC0.00175F11R-TRUEAluSgSINE,Alu
chr237431521AG0.00783CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr299812429AG0.00504MRPL30+TRUEAluSxSINE,Alu
chr19160900TC0.00628.FALSEAluJbSINE,Alu
chr163924020CT0.00139ITGB3BP-FALSE
chr136067760TC0.00052PSMB2-TRUEAluSzSINE,Alu
chr5118175182TC0.00205DTWD2-TRUEAluJrSINE,Alu
chr1206566948GA0.00568SRGAP2+FALSE
chr13100638107AT0.00841ZIC2+FALSE
chr132508397TC0.00166KHDRBS1+FALSE
chr791742141TC0.00100CYP51A1-FALSEAluSx3SINE,Alu
chr2134728113AG0.00531IFNAR1+TRUEAluScSINE,Alu
chr153288894AG8.27269E-06ZYG11B+TRUEAluJoSINE,Alu
chr1181026558GA0.00217MR1+FALSE
chr314986080TC4.44089E-16FGD5-AS1-TRUEFLAM_CSINE,Alu
chr114150032CT0.00163PRDM2+FALSE
chr110518921CT0.00398.FALSEAluSx3SINE,Alu
chr1185069687CT0.00072RNF2+FALSE
chr856985608AT0.00077RPS20-FALSE
chr1228520973CG0.00875OBSCN+FALSE
chr345722287AG0.00197LIMD1,LIMD1-AS1+,-FALSEAluSzSINE,Alu
chr2118854088CT0.00543INSIG2+FALSE
chr75410425GC0.00043TNRC18-FALSE(CACCGC)nSINE,Alu
chr5141690819GA0.00062SPRY4-FALSE
chr2101893247CA0.00237RNF149-FALSE(A)nSINE,Alu
chr1742880118TC0.00140GJC1-TRUEAluJbSINE,Alu
chr1212515613CT0.00286PPP2R5A+FALSE
chr261705067AT0.00084.FALSE
chr340503557TC0.00746RPL14+FALSE
chr1958356524AG0.00026ZNF587B+TRUEAluSxSINE,Alu
chr1114443474AG9.14620E-06AP4B1-AS1,AP4B1+,-FALSEAluSpSINE,Alu
chr811701458TC1.82355E-06CTSB-TRUEAluSx1SINE,Alu
chr2216300795CG0.00641.FALSE
chr1171561859AT0.00439PRRC2C+FALSE
chr110520117TC0.00188.FALSEAluSxSINE,Alu
chr344791062TC0.00035KIAA1143-FALSE
chr193603196GA0.00627MTF2+FALSE
chr110517672TC0.00070.FALSEAluSx1SINE,Alu
chr115905501GA0.00359AGMAT-FALSE
chr1110466466TC0.00377CSF1+FALSE
chr641888827CG0.00936MED20-FALSE
chr1145512951AG0.00180NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr116891365GA1.42078E-05NBPF1-FALSE
chr1184661942TG0.00343EDEM3-FALSE
chr7100031496TA0.00119MEPCE+FALSE
chr126226610CT0.00955STMN1-FALSE
chr11662694TC0.00398SLC35E2-TRUEAluYSINE,Alu
chr12101295434AG0.00695ANO4+FALSE
chr921863618TC0.00148MTAP+FALSEAluYSINE,Alu
chr1931935TC0.00913.FALSE
chr189447720GA0.00521KYAT3,RBMXL1-FALSE
chr186049362CA0.00140CYR61+FALSE
chr275883878TC0.00838MRPL19+FALSEHAL1SINE,Alu
chr128864731AG0.00477RCC1+FALSE
chr153716416GA0.00967LRP8-FALSE
chr9131094270AG0.00686COQ4+TRUEAluSxSINE,Alu
chr830536544TC0.00122GSR-TRUEAluSpSINE,Alu
chr3122283294GC0.00066DTX3L,PARP9+,-FALSE
chr110517623TC8.06723E-05.FALSEAluSx1SINE,Alu
chr720178562TC1.84789E-06MACC1,LOC101927668-TRUEAluYSINE,Alu
chr310192704AG0.00091VHL+TRUEAluSx1SINE,Alu
chr299812446AG0.00461MRPL30+TRUEAluSxSINE,Alu
chr273460310GC0.00091PRADC1-FALSE(CGGCGC)nSINE,Alu
chr1158066834AG0.00609KIRREL+FALSE
chr310192747AG0.00893VHL+TRUEAluSx1SINE,Alu
chr144072066CT0.00846PTPRF+FALSE
chr42516790GT0.00141RNF4+FALSE
chr344692564CG0.00182ZNF35+FALSE
chr1145512123AG3.10159E-05NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1741144250GT0.00025RUNDC1+FALSE
chr6150047430TC0.00568NUP43-TRUEAluScSINE,Alu
chr3193854148TA0.00106HES1+FALSE
chr126449340GA0.00711PDIK1L+FALSE
chr1206566904TC0.00322SRGAP2+FALSE
chr1144595886GA0.00205NBPF20+FALSEAluJbSINE,Alu
chr120826781CT0.00110MUL1-FALSE
chr16282400TC0.00601ICMT-TRUEAluSzSINE,Alu
chr116889413TC8.21040E-06NBPF1-TRUEL1MC4SINE,Alu
chr1156565056CT0.00498GPATCH4-FALSE
chr116944953TG0.00158CROCCP2-FALSE
chrX123047295AG9.23037E-05XIAP+FALSEAluSxSINE,Alu
chr1143186597GA0.00644LOC102723769-FALSE
chr146093161CT0.00628GPBP1L1-FALSE
chr153289892AG0.00505ZYG11B+TRUEFRAMSINE,Alu
chr1224621934GC0.00245WDR26-FALSE(GGA)nSINE,Alu
chr19331227AG0.00181H6PD+TRUEAluSxSINE,Alu
chr2136542427TA0.00075UBXN4+FALSEL1ME4bSINE,Alu
chr3185646406AT0.00023TRA2B-FALSE
chr120977907AG3.34679E-05PINK1,PINK1-AS+,-FALSE
chr1748155425GA0.00603ITGA3+FALSE
chr116932931CA0.00191NBPF1-FALSEL1MC2SINE,Alu
chr733060946AG0.00542NT5C3A-FALSE
chr8145159713GC0.00137MAF1+FALSE
chr342594019CT3.51223E-05SEC22C-FALSE
chr165898263AG0.00767LEPR,LEPROT+FALSEMIRcSINE,Alu
chr131405694GA0.00986PUM1-FALSE
chr116932783GC0.00843NBPF1-FALSEL1MC2SINE,Alu
chr237330534TC6.35640E-05.FALSEAluSq2SINE,Alu
chr1252710721GC0.00519KRT83-FALSE
chr193308168TA0.00314FAM69A-FALSE
chr18931947TC0.00059ENO1-FALSE
chr11152309AT0.00035SDF4-FALSE
chr744918672TC0.00150PURB-TRUEAluSgSINE,Alu
chr1205501469AG0.00113CDK18+FALSE
chr110520174TC0.00158.FALSEAluSxSINE,Alu
chr6150045852TC0.00204NUP43-TRUEAluSqSINE,Alu
chr228636644AG0.00918FOSL2+FALSE
chr5140482871TG0.00650PCDHB3+FALSE
chr1120539742GA0.00469NOTCH2-FALSE
chr237330146CG2.68632E-05.FALSE
chr99442082TG0.00052PTPRD-FALSE7SLRNASINE,Alu
chr9116022893CA0.00060SLC31A1+FALSE
chr1194801632CA0.00194SRSF8+FALSE
chr1945406538CG0.00119TOMM40+FALSE
chr1114306369AT0.00834RSBN1-FALSE
chr194982784TA0.00179ABCD3+FALSE
chr210194192TC0.00715KLF11+FALSE
chr110517613TC0.00499.FALSEAluSx1SINE,Alu
chr285132775CG7.25564E-06TMSB10+FALSE
chr1120839682AG0.00073FAM72B+FALSE
chr153291435AG0.00790ZYG11B+TRUEAluJrSINE,Alu
chr1757281060AG0.00026PRR11+TRUEAluSzSINE,Alu
chr170718278CG0.00663.FALSE
chr4160280309GT0.00770RAPGEF2+FALSE(T)nSINE,Alu
chr155316322AG0.00266DHCR24-FALSE
chr488061645TA0.00049AFF1+FALSE(TATAT)nSINE,Alu
chr489181451TC8.32748E-05PPM1K-TRUEAluSx1SINE,Alu
chr46675519AC0.00064LOC105374366-FALSE
chr1148004525CT0.00541NBPF8-FALSE
chr140537924GA0.00476CAP1+FALSE(A)nSINE,Alu
chr224225006AG0.00141.FALSEAluSxSINE,Alu
chr133148361GC0.00428SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr5125961447AG0.00242PHAX+TRUEAluSz6SINE,Alu
chr1153617980AG0.00272CHTOP+FALSE
chr1256215097AT0.00051DNAJC14-FALSE
chr119543973TC0.00236LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr457326291AG0.00424PAICS+TRUEAluJrSINE,Alu
chr261405795GT0.00061AHSA2+FALSE
chr16582558TC0.00030NOL9-TRUEAluSx1SINE,Alu
chr3195963395AG0.00028.FALSE
chr126755643AG0.00955LIN28A+FALSEAluScSINE,Alu
chr239009427AG1.04745E-05.FALSEAluSx3SINE,Alu
chr624719384AC0.00215C6orf62-FALSE(A)nSINE,Alu
chr417802890TC0.00303DCAF16-TRUEAluSzSINE,Alu
chr128662157AG0.00159MED18+TRUEAluSq2SINE,Alu
chr1145689533AG0.00618NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr197084638AG0.00508ZNF557+TRUEAluJbSINE,Alu
chr1742113064AG0.00014LSM12-FALSE(A)nSINE,Alu
chr116892135GA0.00221NBPF1-FALSE
chr116889566TC0.00305NBPF1-TRUE
chr135650022CA0.00762SFPQ-FALSE
chr145279900TC0.00073.FALSE(TCTT)nSINE,Alu
chr1145441838CG0.00790NBPF20,NBPF10,TXNIP+FALSE
chr2113334241AG0.00388POLR1B+TRUE
chr1220231946TC0.00439RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr135648712GA0.00298SFPQ-FALSE
chr1207247477TC2.68116E-05PFKFB2+FALSEMER5BSINE,Alu
chr2206986949TC0.00693.FALSEAluJrSINE,Alu
chr540826638CA0.00749LOC100506548-FALSELTR78SINE,Alu
chr352084040CT4.81509E-06DUSP7-FALSE
chr417804785TC0.00083DCAF16-TRUEAluSxSINE,Alu
chr3122293773AT0.00852DTX3L+FALSE
chr12335348CT0.00018RER1+FALSE
chrX3526615GT0.00820PRKX-FALSE
chr110368093CA0.00131KIF1B+FALSE
chr116574382AC0.00704FBXO42-FALSE
chr2234775941AG0.00161MSL3P1-FALSE
chr2219146868TC0.00764PNKD,TMBIM1+,-FALSE
chr1246931057AG0.00048SCCPDH+FALSE
chr112628188TC3.43513E-08DHRS3-FALSE

Differential Expression Gene Analysis