Dataset Overview
RBP
PNPT1
Knock-Method
shRNA
RBP Family
RNase_PH
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR880DEH
Platform
HiSeq
Pubmed ID
32252787
PNPT1 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of PNPT1
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1CF
30.66
18.68
-0.71179
3.86555E-12
3.22497E-11
A2M
2149.68
2526.12
0.50507
5.34336E-07
2.28542E-06
A4GALT
0.85
1.31
0.95337
0.00232
0.00511
AAAS
25.65
14.0
-0.80210
4.96430E-12
4.07958E-11
AADAT
4.81
1.29
-1.80727
2.14669E-20
4.07221E-19
AAED1
6.5
6.61
0.37584
0.00686
0.01365
AAK1
2.42
4.89
1.33463
4.13825E-19
6.88749E-18
AAMDC
23.01
26.84
0.43884
0.00341
0.00726
AARS
64.38
156.38
1.48764
1.41730E-44
1.54205E-42
AARS2
4.86
2.08
-1.03695
1.03222E-12
9.20680E-12
Showing 1 to 10 of 8,235 entries
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Function Analysis of Target Genes of PNPT1
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC2
101556540_101556610_101554169_101554225_101556853_101557853
0.00371
0.101
DataSet_01_241
View details
ABCC2
101576820_101576911_101572774_101572901_101577064_101577241
0.00873
0.117
DataSet_01_241
View details
AC007246.3
39701667_39701768_39681437_39681506_39743554_39743682
0.00378
-0.261
DataSet_01_241
View details
AC027612.6
91831165_91831379_91805185_91806180_91842945_91843023
0.00675
-0.092
DataSet_01_241
View details
AC093838.4
132277386_132277551_132277107_132277239_132277669_132279145
0.00721
0.326
DataSet_01_241
View details
ACAD10
112148076_112148241_112147329_112147488_112150301_112150461
0.00819
0.619
DataSet_01_241
View details
ACADM
76252384_76252550_76251717_76251959_76253181_76253260
0.00065
0.084
DataSet_01_241
View details
ACADM
76252384_76252539_76251717_76251959_76253181_76253260
0.00163
0.07
DataSet_01_241
View details
ACADM
76252384_76252601_76251717_76251959_76253181_76253260
0.00212
0.069
DataSet_01_241
View details
ACADM
76252384_76252482_76251717_76251959_76253181_76253260
0.00247
0.089
DataSet_01_241
View details
Showing 1 to 10 of 463 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9264754_9264807_9264904_9265132_9262909_9262930
0.00000
-0.223
DataSet_01_241
View details
ACAD10
112148076_112148241_112150301_112150461_112147329_112147488
0.00752
0.603
DataSet_01_241
View details
ACTR1B
98277033_98277109_98278344_98278409_98275814_98275940
0.00683
-0.177
DataSet_01_241
View details
AHSG
186336351_186336426_186337645_186337702_186334975_186335139
0.00000
-0.199
DataSet_01_241
View details
AHSG
186336285_186336426_186337645_186337735_186334975_186335139
0.00000
-0.19
DataSet_01_241
View details
AHSG
186336300_186336426_186337645_186337735_186334975_186335139
0.00000
-0.184
DataSet_01_241
View details
AHSG
186334975_186335164_186337645_186337729_186334231_186334316
0.00129
0.113
DataSet_01_241
View details
AHSG
186336285_186336426_186337645_186337702_186334975_186335139
0.00136
-0.075
DataSet_01_241
View details
AHSG
186336300_186336426_186337645_186337702_186334975_186335139
0.00158
-0.07
DataSet_01_241
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AHSG
186336079_186336280_186336351_186336426_186334975_186335139
0.00680
-0.003
DataSet_01_241
View details
Showing 1 to 10 of 113 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACSS2
33509588_33509795_33509588_33509669_33511125_33511234
0.00116
0.045
DataSet_01_241
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AHSA2
61411846_61412059_61411846_61411935_61412636_61412881
0.00270
0.036
DataSet_01_241
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ALB
74275071_74275183_74275071_74275140_74276028_74276126
0.00210
0.014
DataSet_01_241
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ARPC4-TTLL3
9874787_9874957_9874787_9874929_9876364_9877085
0.00450
-0.54
DataSet_01_241
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ATG4B
242610726_242610966_242610726_242610820_242611605_242612007
0.00583
0.084
DataSet_01_241
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BRD2
32945902_32946165_32945902_32946091_32947604_32947909
0.00612
0.026
DataSet_01_241
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CALD1
134617738_134618828_134617738_134618141_134625842_134625988
0.00000
0.117
DataSet_01_241
View details
CERS4
8320705_8320920_8320705_8320763_8321119_8321170
0.00089
0.126
DataSet_01_241
View details
CHPT1
102120071_102120295_102120071_102120182_102122678_102122852
0.00000
0.194
DataSet_01_241
View details
CHPT1
102120071_102120275_102120071_102120182_102122678_102122852
0.00006
0.153
DataSet_01_241
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Showing 1 to 10 of 42 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABLIM1
116207638_116207785_116207638_116207779_116211382_116211430
0.00819
0.156
DataSet_01_241
View details
AC040977.1
6915927_6916096_6915927_6916076_6916984_6917062
0.00070
0.06
DataSet_01_241
View details
AC040977.1
6915927_6916080_6915927_6916076_6916984_6917062
0.00077
0.052
DataSet_01_241
View details
AP1G2
24033254_24033430_24033254_24033368_24033541_24033597
0.00051
0.149
DataSet_01_241
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APOA2
161192707_161192820_161192707_161192784_161193139_161193215
0.00065
0.066
DataSet_01_241
View details
APOA2
161192707_161193056_161192707_161192784_161193139_161193215
0.00194
0.018
DataSet_01_241
View details
ARFGEF2
47589681_47589821_47589782_47589821_47588862_47588962
0.00910
-0.2
DataSet_01_241
View details
ATP6V1G2-DDX39B
31508190_31508343_31508190_31508311_31509726_31509925
0.00645
0.16
DataSet_01_241
View details
BBS2
56532348_56532608_56532348_56532480_56533689_56533819
0.00150
0.145
DataSet_01_241
View details
BPHL
3129220_3129432_3129278_3129432_3127475_3127642
0.00330
0.194
DataSet_01_241
View details
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACADVL
7125985_7126556_7125985_7126184_7126451_7126556
0.00131
-0.106
DataSet_01_241
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AFMID
76201576_76201819_76201576_76201599_76201683_76201819
0.00010
-0.16
DataSet_01_241
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AKR1B1
134132049_134132813_134132049_134132133_134132731_134132813
0.00060
0.088
DataSet_01_241
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AKT1
105237081_105238789_105237081_105237184_105238701_105238789
0.00804
-0.025
DataSet_01_241
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ANKZF1
220098854_220100034_220098854_220099010_220099547_220100034
0.00092
-0.13
DataSet_01_241
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AP1G2
24030720_24031624_24030720_24030844_24031170_24031624
0.00105
0.137
DataSet_01_241
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ARFGAP1
61918915_61921140_61918915_61920848_61921029_61921140
0.00284
-0.13
DataSet_01_241
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ATF4
39916568_39917676_39916568_39916756_39917358_39917676
0.00000
-0.042
DataSet_01_241
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C17orf76-AS1
16342350_16342728_16342350_16342374_16342640_16342728
0.00003
0.097
DataSet_01_241
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CBS
44473300_44474093_44473300_44473757_44473971_44474093
0.00156
-0.132
DataSet_01_241
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
89447854
G
T
0.00310
KYAT3,RBMXL1
-
FALSE
chr1
150937771
T
A
0.00026
CERS2
-
FALSE
(ATTTTTT)n
SINE,Alu
chr1
160965379
T
C
0.00477
F11R
-
TRUE
AluSc
SINE,Alu
chr1
67874697
T
C
0.00642
SERBP1
-
TRUE
AluSx3
SINE,Alu
chr1
16945780
C
T
0.00034
CROCCP2
-
FALSE
chr1
10517550
T
C
0.00457
.
FALSE
AluSx1
SINE,Alu
chr1
9162247
T
C
0.00549
.
FALSE
AluSx
SINE,Alu
chr1
9328120
A
G
0.00386
H6PD
+
TRUE
AluJr
SINE,Alu
chr1
32697071
C
A
0.00134
EIF3I
+
FALSE
AluSp
SINE,Alu
chr1
67874849
T
C
0.00169
SERBP1
-
TRUE
AluSx
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression