Dataset Overview
RBP
PUM2
Knock-Method
shRNA
RBP Family
PUF
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR210DML
Platform
HiSeq
Pubmed ID
32252787
PUM2 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of PUM2
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
15.89
7.79
-0.94365
4.87349E-09
3.46931E-08
A2M
2149.68
1500.09
-0.53713
2.44193E-07
1.33026E-06
A4GALT
0.85
2.54
1.69839
3.38466E-12
3.50732E-11
AADAC
0.57
1.09
0.88305
0.00648
0.01446
AADAT
4.81
7.56
0.40220
0.00281
0.00688
AAED1
6.5
4.16
-0.82794
4.30142E-10
3.47700E-09
AAGAB
8.9
15.81
0.63231
2.24534E-07
1.22856E-06
AAK1
2.42
4.35
0.87953
4.22928E-10
3.42249E-09
AAMDC
23.01
19.09
-0.37708
0.02235
0.04281
AAR2
19.98
16.82
-0.38674
4.88879E-05
0.00018
Showing 1 to 10 of 7,965 entries
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Function Analysis of Target Genes of PUM2
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCB1
87196100_87196212_87195385_87195557_87199487_87199539
0.00702
-0.141
DataSet_01_242
View details
ABCG5
44041408_44041459_44039698_44040448_44041615_44041728
0.00952
0.082
DataSet_01_242
View details
AC093838.4
132277386_132277515_132277107_132277239_132277669_132277994
0.00729
-0.172
DataSet_01_242
View details
ACAA1
38173086_38173129_38170780_38170879_38173416_38173496
0.00005
-0.16
DataSet_01_242
View details
ACADM
76252384_76252482_76251717_76251959_76253181_76253260
0.00720
0.086
DataSet_01_242
View details
ACADSB
124797244_124797363_124793871_124794031_124799981_124800188
0.00333
0.055
DataSet_01_242
View details
ACSF2
48541886_48541960_48541608_48541655_48548388_48548761
0.00002
0.2
DataSet_01_242
View details
AFP
74320952_74321007_74319481_74319614_74321347_74321891
0.00168
0.007
DataSet_01_242
View details
AHSG
186336351_186336426_186334975_186335139_186338374_186339107
0.00000
0.212
DataSet_01_242
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AHSG
186336285_186336426_186334975_186335139_186338374_186339107
0.00001
0.121
DataSet_01_242
View details
Showing 1 to 10 of 262 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52603747_52603882_52619601_52619745_52601621_52601752
0.00529
-0.129
DataSet_01_242
View details
ACAA1
38169276_38169357_38170780_38170879_38168000_38168191
0.00000
-0.161
DataSet_01_242
View details
ACAA1
38173416_38173496_38175442_38175500_38170780_38170879
0.00672
-0.187
DataSet_01_242
View details
ACAA1
38170780_38170879_38173086_38173129_38167652_38168191
0.00909
-0.482
DataSet_01_242
View details
ACADVL
7126451_7126556_7126962_7127049_7126078_7126184
0.00001
-0.083
DataSet_01_242
View details
ACLY
40052872_40052902_40054001_40054092_40049285_40049427
0.00042
0.143
DataSet_01_242
View details
AGMAT
15904179_15904359_15905353_15905549_15901251_15901336
0.00412
0.181
DataSet_01_242
View details
AHSG
186336079_186336280_186336324_186336426_186334975_186335139
0.00001
-0.011
DataSet_01_242
View details
AHSG
186336079_186336280_186336351_186336426_186334975_186335139
0.00001
-0.241
DataSet_01_242
View details
AHSG
186336079_186336280_186336285_186336426_186334975_186335139
0.00004
-0.171
DataSet_01_242
View details
Showing 1 to 10 of 116 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACP1
271892_272065_271892_271939_272191_272305
0.00588
-0.099
DataSet_01_242
View details
APEX1
20923423_20923535_20923423_20923429_20923736_20923831
0.00025
-0.201
DataSet_01_242
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C11orf74
36616062_36616191_36616062_36616142_36631630_36631789
0.00799
-0.356
DataSet_01_242
View details
C14orf159
91681748_91682137_91681748_91681900_91691027_91691699
0.00204
0.506
DataSet_01_242
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C17orf76-AS1
16342640_16343017_16342640_16342728_16343498_16343567
0.00622
0.097
DataSet_01_242
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CALD1
134617738_134618828_134617738_134618141_134625842_134625988
0.00682
0.046
DataSet_01_242
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DHRS2
24113617_24113763_24113617_24113704_24114035_24114091
0.00215
-0.109
DataSet_01_242
View details
DPY19L1P1
32662972_32663051_32662984_32663051_32660624_32660684
0.00888
0.154
DataSet_01_242
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FGFR4
176513905_176514034_176513905_176514019_176516550_176516694
0.00589
0.078
DataSet_01_242
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FKBP10
39974639_39974854_39974639_39974779_39975461_39975651
0.00000
0.173
DataSet_01_242
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Showing 1 to 10 of 25 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCD4
74759450_74759635_74759450_74759572_74759856_74759951
0.00393
-0.218
DataSet_01_242
View details
ABHD14A-ACY1
52020968_52021077_52021003_52021077_52020620_52020677
0.00666
0.051
DataSet_01_242
View details
ALAD
116154398_116154615_116154398_116154449_116155726_116155914
0.00407
0.177
DataSet_01_242
View details
APOA2
161193139_161193247_161193139_161193215_161193384_161193421
0.00538
0.043
DataSet_01_242
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ASNS
97483891_97484066_97483891_97483992_97484664_97484771
0.00688
-0.025
DataSet_01_242
View details
C17orf76-AS1
16342894_16343567_16343498_16343567_16342640_16342728
0.00094
0.145
DataSet_01_242
View details
C1orf63
25570040_25570715_25570040_25570124_25570944_25570989
0.00873
-0.194
DataSet_01_242
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CERS2
150939231_150939373_150939231_150939338_150939549_150939678
0.00484
0.021
DataSet_01_242
View details
CNOT11
101874252_101874417_101874299_101874417_101869263_101869940
0.00067
-0.121
DataSet_01_242
View details
DDB1
61070517_61070727_61070517_61070627_61071336_61071507
0.00451
0.494
DataSet_01_242
View details
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCF3
183905184_183905549_183905184_183905231_183905451_183905549
0.00258
0.156
DataSet_01_242
View details
ABHD14A-ACY1
52020968_52021212_52020968_52021077_52021162_52021212
0.00573
0.167
DataSet_01_242
View details
ACADVL
7125985_7126556_7125985_7126184_7126451_7126556
0.00013
0.13
DataSet_01_242
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AP1G2
24032924_24033430_24032924_24033065_24033254_24033430
0.00579
-0.105
DataSet_01_242
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BHLHE40
5021646_5022093_5021646_5021716_5021985_5022093
0.00084
0.037
DataSet_01_242
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C17orf76-AS1
16342640_16343567_16342640_16342728_16342894_16343567
0.00739
-0.074
DataSet_01_242
View details
C17orf76-AS1
16342640_16343567_16342640_16343017_16343498_16343567
0.00594
-0.025
DataSet_01_242
View details
CCNG1
162864576_162864810_162864576_162864670_162864770_162864810
0.00760
-0.141
DataSet_01_242
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CFB
31915721_31916289_31915721_31915858_31916150_31916289
0.00028
-0.045
DataSet_01_242
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CHMP2A
59062932_59063334_59062932_59063143_59063272_59063334
0.00434
0.072
DataSet_01_242
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
179077613
T
C
0.00731
ABL2
-
FALSE
chr1
10520378
T
C
0.00743
.
FALSE
AluSx1
SINE,Alu
chr1
62627128
A
G
0.00087
PATJ
+
TRUE
AluSx
SINE,Alu
chr1
110136329
G
T
0.00993
GNAI3
+
FALSE
chr1
26143697
G
C
0.00778
SEPN1
+
FALSE
chr1
3416449
C
A
0.00748
MEGF6
-
FALSE
chr1
117644949
C
G
0.00862
TTF2
+
FALSE
chr1
67451522
A
T
0.00949
MIER1
+
FALSE
chr1
160967833
T
C
0.00717
F11R
-
TRUE
AluSp
SINE,Alu
chr1
109192040
T
C
6.39517E-05
HENMT1
-
TRUE
AluJr
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression