Dataset Overview
RBPEIF3A
Knock-MethodshRNA
RBP FamilyNon-canonical_RBP
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR258VGD
PlatformHiSeq
Pubmed ID32252787

EIF3A - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of EIF3A
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of EIF3A


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1109475569AG0.00046GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr2191224981GT0.00676INPP1+FALSE
chr1256215099TA0.00227DNAJC14-FALSE
chr13545199GC0.00188TPRG1L+FALSE
chr110520684TC0.00125DFFA-TRUEAluSc8SINE,Alu
chr1542859452AG0.00123HAUS2+TRUEAluJbSINE,Alu
chr517276080AC0.00298BASP1+FALSE(TC)nSINE,Alu
chr269548320CT7.68354E-05GFPT1-FALSE
chr239009425AG0.00607.FALSEAluSx3SINE,Alu
chr3195961254CT0.00119.FALSE
chr262095566CT0.00471CCT4-FALSE
chr11668168GT0.00344SLC35E2-FALSEAluSzSINE,Alu
chr765888510TC0.00519.FALSE
chr3184766301TC0.00648VPS8+FALSE
chr138278949CA0.00664MTF1-FALSEAluSpSINE,Alu
chr1098281496TC0.00509TM9SF3-FALSE
chr39821914CT7.78954E-06TADA3-FALSE
chr174672474GA0.00014FPGT-TNNI3K,FPGT+FALSEX12_DNASINE,Alu
chr1113243048CT0.00023MOV10+FALSE
chr1939220786CA0.00303ACTN4+FALSEA-richSINE,Alu
chr5178986978CG0.00341RUFY1+FALSE
chr3181430334GA0.00305SOX2-OT,SOX2+FALSE
chr155207982CA0.00063MROH7-TTC4,TTC4+FALSE
chr1145329095CG0.00261NBPF20,NBPF10+FALSE
chr120519808GA0.00882UBXN10+FALSE
chr1760522250AG0.00267METTL2A+FALSE
chr6149915565AG0.00198RPS18P9+FALSE
chr1256215097AT0.00051DNAJC14-FALSE
chr136642420TC0.00358MAP7D1+FALSE
chr611577085CT1.34362E-05TMEM170B+FALSE
chr413583889TC2.08207E-10BOD1L1-FALSE
chr237331269TC0.00781.FALSEAluSx1SINE,Alu
chr128834154GT0.00012SNHG3,RCC1+FALSEAluSgSINE,Alu
chr5179665201CT0.00037MAPK9-FALSEAluSx4SINE,Alu
chr1114940228CT0.00252TRIM33-FALSE(T)nSINE,Alu
chr552393421CT0.00144MOCS2-FALSEL1MA9SINE,Alu
chr1175526481CA0.00995UVRAG+FALSE
chr110519982TC0.00572.FALSEAluJrSINE,Alu
chr119543353TC0.00077LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr117766126AG0.00017RCC2-FALSE
chr841798912TC0.00892KAT6A-FALSE
chr13806074GA0.00809C1orf174-FALSEAluSpSINE,Alu
chr613788045TC0.00157MCUR1-TRUE
chr1186946912GA0.00414PLA2G4A+FALSE
chr1145283718GA0.00897NBPF20,NOTCH2NL+FALSE
chr154691921GA0.00010SSBP3-FALSE
chr7156763332AG0.00090NOM1+TRUEAluSxSINE,Alu
chr495586727GT0.00996PDLIM5+FALSE
chr111084103TA0.00146TARDBP+FALSE
chr261386572CG0.00821C2orf74+FALSEAluSzSINE,Alu
chr11118947634CT0.00276VPS11+FALSE
chr247401264CG9.89170E-05CALM2-FALSE
chr439552022TC0.00015UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr1148252049AC0.00666NBPF8,NBPF14,NBPF9-FALSE
chr1156613517CA0.00011BCAN+FALSE
chr1117945040GA0.00181MAN1A2+FALSE
chr1120164994CT0.00829ZNF697-FALSE
chr151434560GA0.00685CDKN2C+FALSE
chr2206987632TC0.00671.FALSEAluJbSINE,Alu
chr1121134169AT0.00660SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSE(TTTCCT)nSINE,Alu
chr3184429718AG0.00914MAGEF1-FALSE
chr110518826TC0.00292.FALSEAluSx1SINE,Alu
chr1153533813AT0.00451S100A2-FALSE
chr2128602974AT4.23982E-05.FALSEAluSpSINE,Alu
chrX119572534CA0.00387LAMP2-FALSE
chr5154194420GA0.00137LARP1+FALSE
chr45830393CT0.00220CRMP1-FALSE
chr570248478GA0.00229SMN1,SMN2+FALSEL1MC5aSINE,Alu
chr153289892AG0.00079ZYG11B+TRUEFRAMSINE,Alu
chr147840938AG0.00089CMPK1+FALSE
chr356654248TG3.99921E-06CCDC66,FAM208A+,-FALSE
chr291843471CT0.00095LOC654342-FALSE
chr1204526795AG0.00199MDM4+TRUEAluSxSINE,Alu
chr344791554TC7.29341E-07KIAA1143-FALSEAluJrSINE,Alu
chr1153617980AG8.13079E-05CHTOP+FALSE
chr167451522AT0.00883MIER1+FALSE
chr1144815953AG0.00348NBPF20,NBPF9+FALSE
chr42940085TC0.00801NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr11650797AG0.00325CDK11B,CDK11A-FALSE
chr1158631171AC0.00815SPTA1-FALSE
chr120510981GC0.00197UBXN10-AS1-FALSE
chr1149913733TC0.00143OTUD7B-TRUEMER96BSINE,Alu
chr8101269589AT0.00281RNF19A-FALSE
chr285772407TA0.00232GGCX-FALSE
chr128835934AG0.00596SNHG3,RCC1+TRUEAluSx4SINE,Alu
chrX118672577TC0.00080CXorf56-TRUEAluSxSINE,Alu
chr1738798073TG0.00692SMARCE1-FALSE
chr495173779TC0.00771SMARCAD1+FALSE
chr128608338AG0.00341SESN2+FALSE
chr119542415TC0.00204LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr2120980896TG0.00132TMEM185B-FALSE
chr1274934944AG0.00094ATXN7L3B+FALSE
chr8146035211TC0.00116ZNF517+FALSEAluSx1SINE,Alu
chr119543247TC5.23836E-05LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr238971639AT0.00019SRSF7-FALSE
chr1047221465TC0.00201.FALSEAluJbSINE,Alu
chr170718273AT0.00256.FALSE
chr11419775AG0.00090ATAD3B+TRUEAluYk2SINE,Alu
chr1450792837AG0.00550ATP5S+TRUEAluSxSINE,Alu
chr120826788AT6.12716E-05MUL1-FALSE
chr457326873AG0.00034PAICS+TRUEAluSx1SINE,Alu
chr3126755556CT0.00303PLXNA1+FALSE
chr1228881129AG0.00199RHOU+FALSE
chr12123347005TA0.00268HIP1R+FALSE
chr2174090332AC0.00918ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr18413839AG0.00776RERE-FALSE
chr11595602AG9.14189E-05CDK11B,SLC35E2B-FALSEAluJrSINE,Alu
chr345959759TC0.00818FYCO1-FALSE
chr111159823TC0.00186EXOSC10,LOC105376736+,-FALSE
chr1326499AG0.00583.FALSE
chr110521238TC0.00797DFFA-TRUEAluYSINE,Alu
chr1774561213AG0.00241SNHG16+FALSE
chr194351064AT0.00620GCLM-FALSE
chr1373651653GT0.00532KLF5+FALSE
chr116913612GA0.00145NBPF1-FALSE
chr124746451AG0.00683NIPAL3+TRUEAluScSINE,Alu
chr579279309TG0.00167MTX3-FALSE
chr146077268AG0.00012NASP+TRUEAluSc8SINE,Alu
chr239212567TG0.00546SOS1-FALSE
chr5126171974CT0.00867LMNB1+FALSE
chr6109785909TC0.00556MICAL1,ZBTB24-TRUEAluJrSINE,Alu
chr1118552269TA0.00066.FALSEAluJrSINE,Alu
chr158999651TG0.00980OMA1-FALSE
chr136773405TG0.00546SH3D21+FALSE
chr159124223GA0.00327MYSM1-FALSEMIR3SINE,Alu
chr1734942575GA0.00374GGNBP2+FALSEA-richSINE,Alu
chr456295161TA0.00075CLOCK-FALSE(T)nSINE,Alu
chr19161011TC7.97270E-05.FALSEAluJbSINE,Alu
chr540829980TC0.00752.FALSEAluSpSINE,Alu
chr2134728099AG1.57787E-05IFNAR1+TRUEAluScSINE,Alu
chr2239355561AG0.00343ASB1+FALSE
chr333481400GC1.12603E-05UBP1-FALSE
chr110516656CT0.00808.FALSE
chr2105964472CT0.00398C2orf49+FALSE(TTTCTCC)nSINE,Alu
chr1145116142AT0.00570NBPF20,SEC22B+FALSE
chr2128064448GT0.00602MAP3K2-FALSE(GT)nSINE,Alu
chr3195694465TC0.00300SDHAP1-FALSE
chr174665493GA0.00128FPGT-TNNI3K,FPGT+FALSE
chr126774225AG0.00614DHDDS+TRUEAluSz6SINE,Alu
chr9131093336TC0.00397COQ4+FALSEAluYSINE,Alu
chr6158093827CT0.00201ZDHHC14+FALSE
chr1523282589AG0.00291HERC2P2-FALSE
chr1475202856AG3.12821E-09FCF1+TRUEAluSxSINE,Alu
chr116717888GA0.00979SZRD1+FALSE
chr190152146CT1.61967E-05LRRC8C+FALSE
chr1611929653CT0.00333RSL1D1-FALSELTR14BSINE,Alu
chr629911970GA0.00284.FALSE
chr1154321623GA0.00782ATP8B2+FALSE
chr179115905TC0.00113IFI44+FALSE
chr417802783TC6.83941E-07DCAF16-TRUEAluSzSINE,Alu
chr274333235CT0.00022TET3+FALSE
chr5177023119TA0.00295TMED9+FALSE
chr12123253851AG0.00470DENR+FALSE(AT)nSINE,Alu
chr2035521049GA0.00711TLDC2,SAMHD1+,-FALSE
chr11344998AG0.00461.FALSEAluSgSINE,Alu
chr1819445881TA0.00224MIB1+FALSE
chr13110407579TG0.00751IRS2-FALSE(T)nSINE,Alu
chr328390351AG1.14010E-06AZI2-FALSE
chr3155660279AG0.00594.FALSE
chr1161488421GT0.00588FCGR2A+FALSEAluSz6SINE,Alu
chr1204525548AG0.00501MDM4+TRUEAluSzSINE,Alu
chr3156259288TC0.00072SSR3-TRUEAluSq2SINE,Alu
chr626095642AG0.00332.FALSEAluYSINE,Alu
chr4190878580AG0.00097FRG1+FALSE
chr133147928AG9.58446E-05SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr3195243006CA7.17300E-06PPP1R2-FALSE
chr4152020782CT0.00989RPS3A+FALSE
chr1563616883AT0.00036CA12-FALSE
chr1681064494AG8.13539E-06CENPN+TRUEAluSgSINE,Alu
chr125169201GT0.00341CLIC4+FALSE
chr1745761110GT0.00816.FALSE
chr1204521160AG0.00231MDM4+TRUEAluSpSINE,Alu
chr42943361TC7.19955E-07NOP14-AS1,NOP14+,-FALSE
chr143391826GT0.00202SLC2A1-FALSE
chr794060360TG0.00014COL1A2+FALSE
chr2191556844TA0.00261NAB1+FALSE
chr1150937961AC0.00060CERS2-FALSEG-richSINE,Alu
chr128835937AG0.00061SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr4113198883GT0.00905TIFA-FALSE
chr227293349CT0.00503AGBL5,OST4+,-FALSE
chr1118167524CT0.00902FAM46C+FALSE
chr1075008731TC8.90942E-06DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr537291636TC0.00518.FALSEAluSx3SINE,Alu
chr1229736656GC0.00793TAF5L-FALSE
chr2204301753TA0.00012RAPH1-FALSE
chr417803604TC0.00206DCAF16-TRUEAluYSINE,Alu
chr116889127AG0.00213NBPF1-FALSEL1MC4SINE,Alu
chr386991597TG0.00481VGLL3-FALSE
chr1201846675CT0.00145IPO9+FALSE
chr1118066459AG1.18472E-05MAN1A2+FALSE
chr1145291217CT0.00075NBPF20+FALSE
chr861655619CT0.00475CHD7+FALSE
chr11571802GA0.00067CDK11B-FALSE
chr5122359499CA0.00277PPIC-FALSE(AC)nSINE,Alu
chr133145959TG0.00755SYNC,RBBP4+,-FALSE(T)nSINE,Alu
chr1114443618AG0.00910AP4B1-AS1,AP4B1+,-FALSEAluSpSINE,Alu
chr145242978AG0.00604RPS8+TRUEAluSzSINE,Alu
chr543609343CT0.00556NNT+FALSE
chr128261658TG0.00280SMPDL3B+FALSE
chr5132232315GA0.00573AFF4-FALSE
chr1180247474TC0.00022.FALSE
chr194352553CT0.00136GCLM-FALSEAluSx1SINE,Alu
chr333185037AC0.00144CRTAP+FALSEL2aSINE,Alu
chr16283434TC0.00285ICMT-TRUEAluSx3SINE,Alu
chr488059664TG0.00178AFF1+FALSE(GT)nSINE,Alu
chr12336210CT0.00206RER1+FALSE
chr1179042544AG0.00722FAM20B+TRUEAluSx1SINE,Alu
chr165897981GA0.00071LEPR,LEPROT+FALSE
chr5442075CA0.00962EXOC3-AS1-FALSE
chr2202030311TA0.00732CFLAR+FALSESVA_ASINE,Alu
chr1959093998AG2.36787E-07CENPBD1P1+TRUEAluYSINE,Alu
chr237327677TC0.00019.FALSE
chr642047426AG0.00676TAF8+TRUEAluSz6SINE,Alu
chr237327702TC2.28397E-07.FALSE
chr117199259GA0.00217LOC440570+FALSE
chr2128064446GT0.00652MAP3K2-FALSE(GT)nSINE,Alu
chr933466219AC0.00148NOL6-FALSE
chr220450819TC0.00807PUM2-TRUE
chr1100657328AG0.00682DBT-FALSE(AC)nSINE,Alu
chr133149376AG0.00424SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr4177252238AG9.63526E-05SPCS3+TRUE
chr1207943211GA0.00248CD46+FALSEAluSx1SINE,Alu
chr1206580084CG0.00104SRGAP2+FALSE
chr1155582104TA0.00099MSTO1+FALSE
chr123833608GA0.00890E2F2-FALSE
chr3196079293TC0.00308.FALSEAluSxSINE,Alu
chr1226333556CA0.00977ACBD3-FALSE(CAAAA)nSINE,Alu
chr3195435168TG0.00111LINC00969+FALSE
chr120977599CG0.00489PINK1,PINK1-AS+,-FALSE
chr140214313AG0.00330PPIE+TRUEAluSq2SINE,Alu
chr11573181CA0.00038CDK11B-FALSE
chr299812447AG0.00501MRPL30+TRUEAluSxSINE,Alu
chr417804785TC0.00083DCAF16-TRUEAluSxSINE,Alu
chr642856917AG0.00148RPL7L1+TRUEAluSpSINE,Alu
chr185113229AG0.00687SSX2IP-FALSE
chr1120612163CA0.00566NOTCH2-FALSE
chr1958420152CA0.00322ZNF417-FALSE
chr114159457AG0.00764RRM1+FALSE
chr7137561078GA0.00558CREB3L2-FALSE(GT)nSINE,Alu
chr2242176182GA2.43141E-09HDLBP-FALSE
chr1474431191AG0.00670ENTPD5-FALSE
chr110521172TC0.00295DFFA-TRUEAluYSINE,Alu
chr153291434AG0.00108ZYG11B+TRUEAluJrSINE,Alu
chr697592897AC0.00144MMS22L-FALSE
chr457326875AG1.03861E-05PAICS+TRUEAluSx1SINE,Alu
chr1453242425TC0.00473GNPNAT1-TRUEAluJoSINE,Alu
chr3109045430GA4.43689E-05DPPA4-FALSE
chr211323079TA0.00586ROCK2-FALSE(TA)nSINE,Alu
chr9111781030CT0.00413TMEM245-FALSEAluJbSINE,Alu
chr2167168093CT0.00789SCN9A-FALSE
chr119586294AG0.00048MRTO4+FALSE
chr145244053AG0.00202RPS8+FALSE
chr110519119TC0.00892.FALSEAluSx3SINE,Alu
chr128564195TC0.00113ATPIF1+FALSE
chr426433556AC3.10862E-15RBPJ+FALSE
chr116891365GA0.00475NBPF1-FALSE
chr115993514CT6.34808E-08.FALSEAluSx4SINE,Alu
chr185785557TA0.00141DDAH1-FALSE
chr11419130AG0.00107ATAD3B+FALSEAluSzSINE,Alu
chr1590819655AG0.00174.FALSEAluSxSINE,Alu
chr540828060TC0.00253LOC100506548-FALSE
chr120945264AC0.00605CDA+FALSE
chr6160101723TC0.00234SOD2-TRUEAluSzSINE,Alu
chr16651728CT0.00118KLHL21-FALSE
chr2206987629TC0.00208.FALSEAluJbSINE,Alu
chr1109818159GT0.00419CELSR2+FALSE
chr16683581AC0.00504PHF13+FALSE
chr128607959CA0.00230SESN2+FALSE
chr193827991AC0.00533DR1+FALSE
chr16582176TC0.00893NOL9-TRUEAluSq4SINE,Alu
chr6160526910AT0.00672IGF2R+FALSE
chr121810903AG0.00154NBPF3+FALSEL1MC4SINE,Alu
chr1648386442AG0.00964LONP2,MIR5095+TRUEAluSz6SINE,Alu
chr574072648TA0.00036NSA2+FALSE
chr417803604TC0.00172DCAF16-TRUEAluYSINE,Alu
chr2189877305TC0.00612COL3A1+FALSE
chr1431916462TC0.00059LOC101927124,DTD2+,-FALSEFLAM_CSINE,Alu
chr119542455TC0.00263LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1206578650GC0.00159SRGAP2+FALSE
chr232532840AG0.00243.FALSEAluSx1SINE,Alu
chr9115446659TC0.00410INIP-TRUEAluJrSINE,Alu
chr1180169330CT0.00374FLJ23867+FALSEMIRSINE,Alu
chr3183861243AG0.00049EIF2B5+FALSE
chr1220323448CT0.00223RAB3GAP2-FALSE
chr110519112TC0.00333.FALSEAluSx3SINE,Alu
chr133086876TC0.00672ZBTB8OS-TRUEAluYSINE,Alu
chr124175288CG0.00646FUCA1-FALSE
chr298388811CG0.00123TMEM131-FALSE
chr4190873405CT0.00325FRG1+FALSE
chr5177576463AT0.00554.FALSE
chr5159492107AT0.00332TTC1+FALSE
chr116133987TC0.00707UQCRHL-FALSE
chr1145281633CA0.00059NBPF20,NOTCH2NL+FALSE
chr1145511988AG0.00965NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr9132268942AG0.00104LINC00963+TRUEAluYf1SINE,Alu
chr5180663940AG0.00331RACK1-FALSE
chrX133930368TG0.00126FAM122B-FALSEG-richSINE,Alu
chr1298942644AG0.00133TMPO+TRUEAluScSINE,Alu
chr1204526713AG0.00078MDM4+TRUEAluSxSINE,Alu
chr121671943TG0.00471ECE1-FALSE(GCTCCCG)nSINE,Alu
chr136068364TC9.25575E-05PSMB2-TRUEAluScSINE,Alu
chr110517952CA0.00341.FALSE
chr1118066459AG1.18146E-05MAN1A2+FALSE
chr1168218543AG7.78857E-07.FALSEAluSzSINE,Alu
chr1214529320TG0.00365PTPN14-FALSEAluJbSINE,Alu
chr3127790249AG0.00057RUVBL1,SEC61A1+,-FALSE
chr2206988452AT0.00669NDUFS1-FALSE
chr1160967856TC0.00027F11R-TRUEAluSpSINE,Alu
chr16582689TC4.44823E-05NOL9-TRUEAluSgSINE,Alu
chr187379494AT0.00364SEP15-FALSE
chr629910604CA0.00144.FALSE
chr119934742GT8.15259E-08MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr210711446TC0.00014NOL10-FALSEMSTASINE,Alu

Differential Expression Gene Analysis