Dataset Overview
RBPDDX3X
Knock-MethodshRNA
RBP FamilyDEAD
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR637JLM
PlatformHiSeq
Pubmed ID32252787

DDX3X - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of DDX3X
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of DDX3X


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr14834606TC0.00647AJAP1+FALSE
chr1145688663TG0.00081NBPF20,NBPF10,RNF115+FALSE
chr1465400786TG0.00077CHURC1-FNTB,CHURC1+FALSEAluSxSINE,Alu
chr1148251875TC0.00436NBPF8,NBPF14,NBPF9-FALSE
chr3148748199CA3.38210E-05HLTF-FALSE
chr722983890TC0.00097FAM126A-FALSE
chr1226809316GA0.00150ITPR2-FALSE
chr2191829133GA0.00097GLS+FALSE
chr2029631604GA0.00045FRG1BP+FALSE
chr110519200TC0.00059.FALSEAluSx3SINE,Alu
chr114604AG0.00304WASH7P-FALSE
chr2198339559GT0.00712COQ10B+FALSE
chr168940566AC0.00126DEPDC1-FALSE
chr2187544223TG0.00254ITGAV+FALSE
chr128661656AG0.00012MED18+TRUEAluSgSINE,Alu
chr49909923GA0.00416SLC2A9-FALSE
chr287777087TC0.00737LINC00152+FALSE
chr1569782TC0.00010.FALSE
chr220192696GA0.00400MATN3,LOC101928222+,-FALSE
chr119542621TC1.78455E-05LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr1146650289CT0.00024PDIA3P1+FALSE
chr286850798AG0.00267RNF103-CHMP3,RNF103-FALSE
chr3100043289CT0.00049TBC1D23+FALSE
chr1154323557CT0.00018ATP8B2+FALSE
chr3183900836GA0.00658AP2M1+FALSE
chr1179042550AG0.00831FAM20B+TRUEAluSx1SINE,Alu
chr110520117TC0.00188.FALSEAluSxSINE,Alu
chr1013687171TC0.00033FRMD4A-FALSE
chr110517290TC0.00437.FALSEAluJrSINE,Alu
chr1143399333TA0.00339.FALSEL1MC4SINE,Alu
chr310192720AG0.00110VHL+TRUEAluSx1SINE,Alu
chr132372387AC0.00757PTP4A2-FALSE(CA)nSINE,Alu
chr123833607AT0.00831E2F2-FALSE
chr211323276TC0.00219ROCK2-FALSE
chr775115154CT0.00405POM121C-FALSE
chr2029631627TC0.00040FRG1BP+FALSE
chr1145512073AG0.00131NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1778091513GA0.00810GAA+FALSE
chr192862896AG6.86172E-05.FALSEAluJrSINE,Alu
chr1150594611GT0.00329ENSA-FALSE
chr159004766GT0.00213OMA1-FALSE
chr167874697TC4.44446E-05SERBP1-TRUEAluSx3SINE,Alu
chr120238573TC0.00204OTUD3+FALSE
chr1743002237CA0.00141KIF18B-FALSE
chr273957124AG2.00679E-05TPRKB-FALSE
chr1298943103AG0.00528TMPO+TRUEAluSzSINE,Alu
chr123833607AT0.00890E2F2-FALSE
chr72278515TC0.00937MRM2-TRUEAluSx1SINE,Alu
chr116889864CA0.00094NBPF1-FALSE
chr121793735CG0.00099NBPF3+FALSE
chr1109780743CA0.00643SARS+FALSE
chr9125887702CT0.00019STRBP-FALSE
chr356763316GA0.00830ARHGEF3-FALSE
chr145975574AG0.00050MMACHC+TRUEAluSx4SINE,Alu
chr1159887904AT8.82173E-05TAGLN2-FALSE
chr13731959CT0.00089CEP104-FALSE
chr126608012CA0.00564SH3BGRL3+FALSE
chr29629293TG0.00426ADAM17-FALSE(TGT)nSINE,Alu
chr136068325TC0.00065PSMB2-TRUEAluScSINE,Alu
chr1113212976CT0.00904CAPZA1+FALSE
chr5139931632CG0.00052SRA1-FALSE
chr237329307TC0.00201.FALSEAluJr4SINE,Alu
chr1160966352TC3.14235E-07F11R-TRUEAluSgSINE,Alu
chr5149823791GT0.00480.FALSE
chr128087457GT0.00178FAM76A+FALSE(T)nSINE,Alu
chr1120163248GA0.00204ZNF697-FALSE
chr1113212976CT0.00332CAPZA1+FALSE
chr349067809TA0.00022QRICH1-FALSE
chr13546137AC0.00778TPRG1L+FALSEAluSzSINE,Alu
chr349315592TC0.00127USP4-FALSE
chr1168220341AG0.00179.FALSEAluSz6SINE,Alu
chr16282401TC0.00806ICMT-TRUEAluSzSINE,Alu
chr627425185CA0.00577ZNF184-FALSE
chr2223765491CT0.00689ACSL3+FALSE
chr136067925TC0.00397PSMB2-TRUEAluSzSINE,Alu
chr3196293764GC0.00392WDR53-FALSE
chr231557839GT0.00145XDH-FALSEAluJrSINE,Alu
chr1148932848AG0.00496LOC645166+FALSE
chr35258280AG4.07938E-08EDEM1+FALSE
chr122854702CT4.66415E-11ZBTB40+FALSE
chr1475202669AG1.13156E-05FCF1+TRUEAluScSINE,Alu
chr124134721TC0.00448HMGCL-FALSE
chr1110912873TC0.00116SLC16A4-FALSE
chr271376999GA0.00546MPHOSPH10+FALSE
chr13697486CG0.00110LRRC47-FALSEAluScSINE,Alu
chr270506337TC0.00313PCYOX1+FALSE
chr5139931634TG6.28154E-05SRA1-FALSE
chr165692499CT0.00516AK4+FALSE(T)nSINE,Alu
chr12120898553AG0.00233GATC+TRUEAluYSINE,Alu
chr738764332TC0.00209VPS41-TRUEAluSpSINE,Alu
chr121086062GT0.00847RAD52-FALSEL2SINE,Alu
chr6170887693GC0.00045PDCD2-FALSE
chr1231468953GA0.00085EXOC8-FALSE
chr775677504CT0.00768MDH2+FALSE
chr312942851CG0.00013IQSEC1-FALSE
chr1220871123AG0.00854C1orf115+FALSE
chr1197125427TC0.00331ZBTB41-FALSE
chr442022464CA0.00059SLC30A9+FALSE
chr1490865627TC0.00162CALM1+FALSE
chr185113229AG0.00687SSX2IP-FALSE
chr119586458AG0.00333MRTO4+TRUEAluSzSINE,Alu
chr5118174735TC0.00046DTWD2-TRUEAluYSINE,Alu
chr236777209TC0.00299CRIM1+FALSE(TG)nSINE,Alu
chr237331107TC0.00020.FALSEAluSx1SINE,Alu
chr2101623611AC0.00826RPL31+FALSE
chr11431502GA0.00127ATAD3B+FALSE
chr1209602381GA0.00057MIR205HG+FALSEAluJbSINE,Alu
chr116889014CA0.00473NBPF1-FALSE
chr2120980896TG0.00132TMEM185B-FALSE
chr119586520AG6.58771E-06MRTO4+TRUEAluSzSINE,Alu
chr211321778GT0.00402ROCK2-FALSEAluSx1SINE,Alu
chr1957818376AG0.00031.FALSEAluJrSINE,Alu
chr29558812GT0.00427ITGB1BP1-FALSE
chr115989141CG0.00677.FALSE
chr119411087CT0.00226UBR4-FALSE
chr1156692054AT0.00471ISG20L2-FALSEAluYSINE,Alu
chr11718810GA5.85228E-05GNB1-FALSE
chr5128430757TC0.00338ISOC1+FALSE
chr110518797TC0.00421.FALSEAluSx1SINE,Alu
chr110502831AG0.00193APITD1,APITD1-CORT+FALSE
chr136522603AG0.00012.FALSEAluScSINE,Alu
chr6114181220AG0.00265MARCKS+FALSE
chr135817022TA0.00072ZMYM4+FALSE
chr4189020293GA0.00361TRIML2-FALSE
chr6107113955AG0.00265QRSL1+TRUEAluSgSINE,Alu
chr1156613632GA0.00187BCAN+FALSE
chr186049361AG0.00036CYR61+FALSE
chr133149443AG0.00897SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr117522430AG0.00684.FALSE
chr3195635455TC0.00158TNK2-FALSE
chr1946053393TC0.00514OPA3-TRUEAluSx1SINE,Alu
chr171946503CG0.00154DPH1,OVCA2+FALSE
chr1117945049GA0.00120MAN1A2+FALSE
chr76501828CA0.00110KDELR2-FALSE
chr19163334TC0.00074.FALSEAluSpSINE,Alu
chr1225678910TC2.51322E-05ENAH-TRUEAluSx1SINE,Alu
chr399515750AG2.61553E-11MIR548G-FALSE
chr153289892AG0.00079ZYG11B+TRUEFRAMSINE,Alu
chr1109747437AG0.00104KIAA1324+TRUEAluJr4SINE,Alu
chr110318652CG0.00047KIF1B+FALSE
chr477057501AG0.00547NUP54-FALSE
chr72274221TC0.00579MRM2-TRUEAluJrSINE,Alu
chr1490509587GT0.00203TDP1+FALSE
chr6109785909TC0.00556MICAL1,ZBTB24-TRUEAluJrSINE,Alu
chr1204525669AG0.00169MDM4+TRUEAluSzSINE,Alu
chr1171751051AG0.00522METTL13+FALSE
chr2206987229TC0.00743.FALSEAluSxSINE,Alu
chr298264656TA0.00993COX5B+FALSE
chr369026314GA0.00881EOGT-FALSEAluSz6SINE,Alu
chr1144931101GA0.00012NBPF20,PDE4DIP+,-FALSE
chr1321547673GA0.00974LATS2-FALSE(TG)nSINE,Alu
chr1179989742GC0.00019CEP350+FALSE
chr119934793GA0.00068MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr1060047611GA0.00855CISD1+FALSE(A)nSINE,Alu
chr146806550CT0.00105NSUN4+FALSE
chr224522807CT0.00079ITSN2-FALSE
chr6114182783AG0.00442MARCKS+FALSE
chr136067760TC0.00203PSMB2-TRUEAluSzSINE,Alu
chr1144595943AG0.00050NBPF20+FALSEAluJbSINE,Alu
chr1206579936AG0.00747SRGAP2+FALSE
chr19162223TC0.00778.FALSEAluSxSINE,Alu
chr6158505088AG0.00083SYNJ2+FALSE
chr340503561AT0.00012RPL14+FALSE
chr1204524842AG0.00044MDM4+TRUEAluSxSINE,Alu
chr1161088583TG0.00745NIT1+FALSE
chr110517653TC0.00776.FALSEAluSx1SINE,Alu
chr826435509TC0.00121DPYSL2+FALSE(TC)nSINE,Alu
chr153291435AG0.00044ZYG11B+TRUEAluJrSINE,Alu
chr9137330714AC0.00030RXRA+FALSE
chr1946052975TC0.00652OPA3-TRUEAluSz6SINE,Alu
chrX77083548TC0.00205MAGT1-TRUEAluSz6SINE,Alu
chr111979815AC0.00274KIAA2013-FALSE
chr1155161702GC0.00020MUC1-FALSE
chr2128620435CA0.00602AMMECR1L-FALSE
chr110517635TC0.00523.FALSEAluSx1SINE,Alu
chr140537922AG0.00686CAP1+FALSE(A)nSINE,Alu
chr3195451488CT1.73907E-06MUC20+FALSE
chr617557416GT0.00885CAP2+FALSE
chr1144815953AG0.00348NBPF20,NBPF9+FALSE
chr1144053567CT0.00037.FALSE
chr4145031951TA0.00377GYPA-FALSE(TG)nSINE,Alu
chr9103064530GA0.00036TEX10-FALSE
chr1352952575GA0.00030THSD1-FALSE
chr179126336CG1.94494E-06IFI44+FALSE
chr1158067060TA0.00114KIRREL+FALSE
chr175171751TC0.00563CRYZ-FALSE
chr629704336GA0.00207.FALSEL1ME3ASINE,Alu
chr261764922GC0.00679XPO1-FALSE
chr8145159712AG0.00402MAF1+FALSE
chr2025428646AG9.98122E-05GINS1+TRUEAluJbSINE,Alu
chr2110842200CA0.00131MALL-FALSE
chr1165877666TC0.00327UCK2+FALSE(T)nSINE,Alu
chr1742876808TC0.00147GJC1-TRUEAluSz6SINE,Alu
chr146076543AG0.00989NASP+TRUEAluSxSINE,Alu
chr1765334725TC2.56338E-07PSMD12-TRUEAluSqSINE,Alu
chr1109884775TG0.00026SORT1-FALSE
chr2224622277TC0.00138AP1S3-TRUEAluSx1SINE,Alu
chr1495572111AC0.00409DICER1-FALSE
chr2174090320TA0.00174ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr261315734AG0.00396KIAA1841+TRUEAluSgSINE,Alu
chr3156259229TC1.62025E-06SSR3-TRUEAluSq2SINE,Alu
chr5125961810AG3.92353E-06PHAX+TRUEFLAM_CSINE,Alu
chr3122283293CG0.00071DTX3L,PARP9+,-FALSE
chr1931939GA0.00428.FALSE
chr1146650289CT0.00736PDIA3P1+FALSE
chr1475202705AG0.00017FCF1+TRUEAluScSINE,Alu
chr2202029998TA0.00350CFLAR+FALSE(TTA)nSINE,Alu
chr540832552GT1.14652E-07RPL37-FALSE
chr1450361170CT0.00096ARF6+FALSE(T)nSINE,Alu
chr110520532TC0.00011.FALSEAluSx1SINE,Alu
chr131344952CT0.00544SDC3-FALSE
chr1143186597GA0.00644LOC102723769-FALSE
chr1144053661TG0.00232.FALSE
chr1145283718GA0.00897NBPF20,NOTCH2NL+FALSE
chr5133956668GA0.00419SAR1B-FALSE
chr764023371TC0.00824ZNF680-FALSE
chr146165437TC0.00090IPP-TRUEFRAMSINE,Alu
chr119071752TC0.00503PAX7+FALSE
chr285548074TC0.00428TGOLN2-FALSE
chr6114181223AG0.00365MARCKS+FALSE
chr237328034TC0.00046.FALSE
chr189649522TC0.00358GBP4-TRUEAluJbSINE,Alu
chr237327670TC5.08697E-08.FALSE
chr1145369589TC0.00128NBPF20,NBPF10+FALSEL1MC4SINE,Alu
chr1168218735AG0.00924.FALSEAluSzSINE,Alu
chr3170021210CA0.00015PRKCI+FALSE
chr21652354GA0.00114PXDN-FALSE
chr595130802AT0.00123RHOBTB3+FALSEAluSzSINE,Alu
chr146662492GA9.93078E-05POMGNT1-FALSE
chr11572530AC0.00425CDK11B-FALSE
chr349714225TC0.00023APEH+FALSE
chr1475202372AG8.84130E-05FCF1+TRUEAluScSINE,Alu
chr1453243434TC0.00421GNPNAT1-TRUEAluSx3SINE,Alu
chr16282237TC0.00395ICMT-TRUEAluSzSINE,Alu
chr2217366897AG0.00440.FALSEAluSz6SINE,Alu
chr12336210CT0.00206RER1+FALSE
chr117735266GA0.00471RCC2-FALSE
chr12133298349AG0.00000PGAM5+TRUEAluSpSINE,Alu
chr1950410816GT0.00050IL4I1,NUP62-FALSEAluSzSINE,Alu
chr16283306TC0.00558ICMT-TRUEAluSx3SINE,Alu
chr115993603GA0.00103.FALSEAluSx4SINE,Alu
chr5115428334GT0.00265COMMD10+FALSE
chr146828700AG0.00805NSUN4+FALSE
chr1149581854CA0.00175LINC00623,LINC00869,LOC103091866+FALSEL2bSINE,Alu
chr5171533782TC0.00039STK10-FALSE
chr365341374TA0.00029MAGI1-FALSE
chr1232532505GA0.00385.FALSE
chr12520435GC0.00041FAM213B+FALSE
chr1154987526CT0.00043ZBTB7B+FALSE
chr127074517CT0.00369PHB2-FALSE
chr111141187CG0.00814EXOSC10-FALSE
chr717384354AG0.00908AHR+TRUEAluSxSINE,Alu
chr16257826TC0.00560RPL22-FALSE
chr1523313171AG0.00257HERC2P2-FALSE
chrM10307AC0.00046.FALSE
chr1160966353TC0.00011F11R-TRUEAluSgSINE,Alu
chr1475202857AG2.23354E-05FCF1+TRUEAluSxSINE,Alu
chr2178406764CT0.00416AGPS+FALSE
chr146075715AG0.00842NASP+TRUEAluSx4SINE,Alu
chr11597356GC0.00995CDK11B,SLC35E2B-FALSE
chr136068369TC5.31121E-05PSMB2-TRUEAluScSINE,Alu
chr1298943202AG6.48893E-05TMPO+TRUEAluSzSINE,Alu
chr1120163007GA0.00573ZNF697-FALSE
chr1474431191AG0.00670ENTPD5-FALSE
chr471683841TC8.62096E-05GRSF1-TRUEAluSzSINE,Alu
chr3196079305TC0.00161.FALSEAluSxSINE,Alu
chrX2825114TC0.00738ARSD-TRUEAluSx1SINE,Alu

Differential Expression Gene Analysis