Dataset Overview
RBPPHF6
Knock-MethodshRNA
RBP FamilyNon-canonical_RBP
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR681SMT
PlatformHiSeq
Pubmed ID32252787

PHF6 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PHF6
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PHF6


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1674698531TC0.00702RFWD3-TRUEAluSx3SINE,Alu
chr4113346996GA0.00191ALPK1+FALSE
chr119542410TC0.00270LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr299813020AG0.00015MRPL30+TRUEAluJbSINE,Alu
chr116889413TC1.64789E-05NBPF1-TRUEL1MC4SINE,Alu
chrX150573750AT0.00887VMA21+FALSE
chr57878179CT0.00014MTRR+FALSE
chr1254634283TC0.00047CBX5-TRUEAluJrSINE,Alu
chr825272425CT0.00605DOCK5+FALSE
chr7102016322AG0.00223LOC100289561,LOC100630923+FALSE
chr1145689028AG9.93195E-07NBPF20,NBPF10+TRUEAluSc8SINE,Alu
chr1120612163CA0.00812NOTCH2-FALSE
chr110518052TC0.00179.FALSEAluJrSINE,Alu
chr1114940227TC0.00852TRIM33-FALSE(T)nSINE,Alu
chr1144053664AC0.00050.FALSE
chr1765334758TC1.31160E-05PSMD12-TRUEAluSqSINE,Alu
chr145975740CG0.00096MMACHC+FALSEAluSx4SINE,Alu
chr536143392CT0.00151LMBRD2-FALSE
chr144072018CT0.00783PTPRF+FALSE
chr136522603AG0.00012.FALSEAluScSINE,Alu
chr6138413269AG0.00743PERP-FALSE
chr119545147TG0.00510LOC101927895,EMC1+,-FALSE
chr170717293GA0.00716SRSF11+FALSE
chr1155582104TA0.00099MSTO1+FALSE
chr315113042CT4.09809E-05RBSN-FALSE
chr1206566948GA0.00879SRGAP2+FALSE
chr145975266AG0.00345MMACHC+TRUEAluSg7SINE,Alu
chr1168220489AG0.00126.FALSEAluSz6SINE,Alu
chr794297293GT0.00573PEG10+FALSE
chr1109818162TC0.00316CELSR2+FALSE
chr2183643905AT0.00841DNAJC10+FALSE
chr1227848053AT0.00090PPFIBP1+FALSE
chr193307479CA0.00019FAM69A,RPL5+,-FALSE
chr11309464CT1.11022E-16AURKAIP1-FALSE
chr3136573440AG0.00038NCK1-AS1,SLC35G2+,-FALSE
chr123631625AG0.00536HNRNPR-FALSEUCON44SINE,Alu
chr297494866CT0.00069CNNM3+FALSE
chr43076659AC0.00401HTT+FALSE(CAG)nSINE,Alu
chr76501830GA0.00110KDELR2-FALSE
chr674134075TC0.00018.FALSEAluYSINE,Alu
chr1108113839TC0.00027VAV3-FALSE
chr115993013GA1.16652E-10.FALSE
chr133149256AG0.00010SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1688763958GA7.55606E-05RNF166-FALSE
chr1100654813TC0.00352DBT-TRUEAluSzSINE,Alu
chr642981526CG0.00129MEA1-FALSE
chr365341374TA0.00029MAGI1-FALSE
chr236706788CG0.00481CRIM1+FALSE
chr9114696428GT0.00163UGCG+FALSE(TGTTTTT)nSINE,Alu
chr140759231AG0.00168ZMPSTE24+FALSE
chr398515569CT3.10862E-15DCBLD2-FALSE
chr1737006214TC0.00706.FALSEAluSxSINE,Alu
chr17263417CT0.00675LOC105371430,C17orf97+,-FALSE
chr717384440AG0.00271AHR+TRUEAluSxSINE,Alu
chr19643195AG0.00294.FALSEAluSxSINE,Alu
chr1214638296GA3.68085E-08PTPN14-FALSE
chr119981865AG0.00213MINOS1-NBL1,NBL1+FALSE
chr1143464946TC0.00109.FALSE
chr194428790AT0.00000CHAF1A+FALSE
chr18212601CA0.00189USP14+FALSEAluSzSINE,Alu
chr2128064446GT0.00652MAP3K2-FALSE(GT)nSINE,Alu
chr154563156AG3.59804E-06TCEANC2+FALSE
chr1757279167AG6.96573E-05PRR11+TRUEAluSq2SINE,Alu
chr116889866GA0.00995NBPF1-FALSE
chr9131872857CG0.00151CRAT-FALSE
chr1942375627AG0.00058.FALSEAluSxSINE,Alu
chr119543361AT0.00076LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr237230734CT0.00025HEATR5B-FALSE
chr140537937AC0.00091CAP1+FALSE(A)nSINE,Alu
chr1757279281AG0.00918PRR11+TRUEAluSq2SINE,Alu
chr246612340GT0.00094EPAS1+FALSE
chr1201438096GT1.87636E-05PHLDA3-FALSE
chr116112795AG1.78234E-05FBLIM1+FALSE
chr349506286GT0.00052DAG1+FALSEAluJbSINE,Alu
chr1168218574AG0.00898.FALSEAluSzSINE,Alu
chr1149913727TC0.00721OTUD7B-TRUEMER96BSINE,Alu
chr110521254TC2.63330E-05DFFA-TRUEAluYSINE,Alu
chr541917694TC0.00784C5orf51+FALSE
chr1765335445TC0.00084PSMD12-TRUEAluSxSINE,Alu
chr1450053315GA0.00150.FALSE7SLRNASINE,Alu
chr11597423CT2.12697E-10CDK11B,SLC35E2B-FALSE
chr116891365GA0.00475NBPF1-FALSE
chr1109865630CT0.00647SORT1-FALSE
chr1450792961GA0.00547.FALSEAluSxSINE,Alu
chr1118502087CT0.00585WDR3,SPAG17+,-FALSE
chrX16782911AG0.00051.FALSEAluJbSINE,Alu
chr161922437GT0.00359NFIA+FALSE
chr119953129TA0.00934MINOS1,MINOS1-NBL1+FALSE
chr186049391TA0.00019CYR61+FALSE
chrM10307AC0.00046.FALSE
chr2113334178AT0.00654POLR1B+FALSEL1MA10SINE,Alu
chr128661576AG0.00625MED18+TRUEAluSgSINE,Alu
chr1623682631CT0.00960DCTN5+FALSE
chr1205111761AC0.00497DSTYK-FALSE
chr1145511796TG0.00173NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSE(T)nSINE,Alu
chr344791406TC0.00598KIAA1143-TRUEAluJrSINE,Alu
chr116952481AG0.00093CROCCP2-FALSE
chr1179042482AG0.00079FAM20B+TRUEAluSx1SINE,Alu
chr186049363CT0.00064CYR61+FALSE
chr2128602366TC0.00236.FALSEAluSq2SINE,Alu
chr17909317GA0.00766ABR-FALSE
chr19162223TC0.00778.FALSEAluSxSINE,Alu
chr138326547CT0.00212INPP5B-FALSEAluJrSINE,Alu
chr2218572728AG0.00050PEX26+TRUEAluYf1SINE,Alu
chr2134728113AG0.00531IFNAR1+TRUEAluScSINE,Alu
chr1688789702GA0.00125PIEZO1-FALSE
chr3169988286CT0.00029PRKCI+FALSE
chr1183218868TG0.00091NMNAT2-FALSE
chr136529575AG2.40551E-05.FALSEAluJrSINE,Alu
chr1144053661TG0.00232.FALSE
chr76501833AT0.00937KDELR2-FALSE
chr125893928TA0.00388LDLRAP1+FALSE
chr1109465174AC0.00234GPSM2+FALSE
chr5125961463AG0.00323PHAX+TRUEAluSz6SINE,Alu
chr1222802926CT0.00035MIA3+FALSE
chr4170017406AT0.00534SH3RF1-FALSE
chr1148556087GC0.00106.FALSE
chr1681064492AG0.00935CENPN+TRUEAluSgSINE,Alu
chr165330637CT0.00047JAK1-FALSE
chr110517313TC0.00015.FALSEAluJrSINE,Alu
chr1535272171TC0.00183ZNF770-FALSE
chr136067677TC5.01583E-07PSMB2-TRUEAluSzSINE,Alu
chr42841551AG0.00258SH3BP2+TRUEAluJrSINE,Alu
chr1227574427AG7.32829E-06ARNTL2,ARNTL2-AS1+,-FALSEAluSzSINE,Alu
chr3150261002CT0.00044SERP1-FALSE
chr131342374AC0.00446SDC3-FALSE(A)nSINE,Alu
chr110520888CT0.00960DFFA-FALSE
chr7128143945AG0.00607.FALSEAluSq2SINE,Alu
chr132661600CT0.00235TXLNA+FALSE(T)nSINE,Alu
chr417803568TC0.00044DCAF16-TRUEAluYSINE,Alu
chr1540462780GA0.00251BUB1B+FALSE
chr193811476GC0.00663.FALSE
chr587566384AT0.00584TMEM161B-AS1+FALSE
chr1168215575GA0.00688ANKRD36BP1-FALSE
chr1117078729AG0.00983CD58-FALSE
chr261369944TC0.00024LOC339803-TRUEAluSxSINE,Alu
chr1861565062CG0.00207SERPINB2+FALSE
chr19161203TC0.00235.FALSEAluSxSINE,Alu
chr116932912TC0.00525NBPF1-FALSEL1MC2SINE,Alu
chr1939433140GT0.00260FBXO17-FALSEAluJbSINE,Alu
chr2018468351TC0.00169RBBP9-TRUEAluSz6SINE,Alu
chr1254526562AT0.00119LOC400043+FALSEL2aSINE,Alu
chr652442880GT5.05556E-08TRAM2-AS1+FALSE
chr1101444071GA0.00963SLC30A7+FALSEMIR3SINE,Alu
chr110596341CT0.00552PEX14+FALSE
chr1145323668GC0.00241NBPF20,NBPF10+FALSE
chr1298942665AG1.31028E-05TMPO+TRUEAluScSINE,Alu
chr128662105AG9.98367E-05MED18+TRUEAluSq2SINE,Alu
chr175671215CT0.00019SLC44A5-FALSE
chr16282361TC0.00634ICMT-TRUEAluSzSINE,Alu
chr1234542410CA0.00832TARBP1-FALSE
chr177759578AG0.00492AK5+FALSE
chr125655853AG0.00147RSRP1,RHD+,-FALSEAluSzSINE,Alu
chr144035352CT0.00170PTPRF+FALSE
chr1179042482AG1.77761E-07FAM20B+TRUEAluSx1SINE,Alu
chr128825427AG0.00484PHACTR4+TRUEAluSgSINE,Alu
chr1778294253AG0.00031RNF213+TRUEAluSpSINE,Alu
chr173512398TC0.00709SHPK,TRPV1-TRUEAluSxSINE,Alu
chr1913054924AC0.00982CALR+FALSE
chr1143189476AG0.00160LOC102723769-FALSE
chr76501830GA0.00217KDELR2-FALSE
chr1145688983AG0.00101NBPF20,NBPF10,RNF115+TRUEAluSc8SINE,Alu
chr352289298GT0.00059WDR82-FALSE
chr120982631GA0.00133DDOST-FALSE
chr238522141GT0.00109ATL2-FALSE
chr189225976TC0.00586PKN2+FALSE
chr11498747TC0.00847SSU72-TRUEAluSg7SINE,Alu
chr19811933CT0.00026PTBP1+FALSE
chr1153914500GA3.11507E-05DENND4B-FALSE
chr5118175329TC2.47285E-05DTWD2-TRUEAluJrSINE,Alu
chr111084105TA0.00116TARDBP+FALSE
chr1145281656AT0.00839NBPF20,NOTCH2NL+FALSE
chr51574319TA0.00158SDHAP3-FALSE
chr830643547TA0.00748PPP2CB-FALSE
chr315114318TC0.00067RBSN-TRUEAluYSINE,Alu
chr170718278CG0.00663.FALSE
chr1237065326CT0.00376MTR+FALSE
chr333907915AG3.74419E-09PDCD6IP+FALSE
chr1220970028AG0.00444MARC1+FALSE
chr1266516911AT0.00067LLPH-FALSE
chr1071993094TG0.00078PPA1-FALSE
chr1204525667AG3.94227E-05MDM4+TRUEAluSzSINE,Alu
chr439550715TC0.00995UGDH-AS1,SMIM14+,-FALSEAluSx1SINE,Alu
chr1779838088TC6.81311E-05.FALSEAluSxSINE,Alu
chr7105162562GC0.00096PUS7-FALSE
chr128825465AG0.00756PHACTR4+TRUEAluSgSINE,Alu
chrX77083845TC0.00102MAGT1-TRUEAluSzSINE,Alu
chr110520764TC0.00542DFFA-TRUEAluSc8SINE,Alu
chr146075192AC0.00045NASP+FALSEA-richSINE,Alu
chr544826677GT0.00941.FALSE(T)nSINE,Alu
chr2202242616GA0.00880TRAK2-FALSE
chr8144662353GA0.00951EEF1D-FALSE
chr116841972GA1.76809E-05.FALSEMER41ESINE,Alu
chr1202993198CA0.00754TMEM183A+FALSE
chr6114181220AG0.00265MARCKS+FALSE
chr16583701TC0.00029NOL9-FALSE
chr2176792535TG0.00211LNPK-FALSE
chr564964627TC0.00998SGTB-TRUEAluSx1SINE,Alu
chr42516791TG4.75740E-05RNF4+FALSE
chr19427842AG0.00923SPSB1+FALSE
chr8144940327GA0.00989EPPK1-FALSE
chr110520058TC0.00907.FALSEAluSxSINE,Alu
chr1629707549AG0.00025QPRT+TRUEAluJrSINE,Alu
chr1151092839AG0.00135GABPB2+TRUEAluSpSINE,Alu
chr2130807905GT0.00634FAR2P1-FALSE
chr1719091395CT0.00852.FALSEU3SINE,Alu
chr116932429CG0.00076NBPF1-FALSEL1MC2SINE,Alu
chr3172115474AG0.00012FNDC3B+FALSE(A)nSINE,Alu
chr1916661541TC0.00120SLC35E1-TRUEAluSzSINE,Alu
chr358308214GA0.00113.FALSELTR49SINE,Alu
chr146159823TA0.00823TMEM69+FALSE
chr119586520AG6.58771E-06MRTO4+TRUEAluSzSINE,Alu
chr140705200GA3.20116E-08RLF+FALSE
chr1145693060AG2.60299E-05NBPF20,NBPF10+TRUEAluSz6SINE,Alu
chr131732599TG0.00827SNRNP40-FALSE
chr2152334349AG0.00171.FALSEAluSqSINE,Alu
chr3115528809TG0.00087LSAMP-FALSE
chr898739208AG0.00686MTDH+TRUEAluSg4SINE,Alu
chr237327670TC5.08697E-08.FALSE
chr1610626624TC0.00334EMP2-FALSE(T)nSINE,Alu
chr11344893AG7.94078E-08.FALSEAluSgSINE,Alu
chr238971641TA0.00071SRSF7-FALSE
chr16283430TC0.00751ICMT-TRUEAluSx3SINE,Alu
chr1100489992AG0.00938SLC35A3+TRUEAluSgSINE,Alu
chr120978516TC0.00774PINK1-AS,DDOST-FALSEAluYSINE,Alu
chr116890598TA0.00428NBPF1-FALSE
chr3195243012AC0.00128PPP1R2-FALSE
chr146075189CA0.00597NASP+FALSEA-richSINE,Alu
chr1148556726GT0.00023.FALSE
chr11595048TC0.00399CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr127205632TC0.00471.FALSEFLAM_ASINE,Alu
chr9140709880CT0.00178EHMT1+FALSE
chr3150262004AT0.00167SERP1-FALSE
chr357126615TC0.00460IL17RD-FALSEAluYSINE,Alu
chr11251631TC0.00256CPSF3L-TRUEAluSzSINE,Alu
chr117393889AG0.00390PADI2-FALSE
chr110520702TC0.00883DFFA-TRUEAluSc8SINE,Alu
chr133148216AG0.00321SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr3179116220TC0.00343GNB4-TRUEAluSz6SINE,Alu
chr919376249GT5.55883E-05.FALSE
chr133219771GC0.00256KIAA1522+FALSE
chr1919793709AG0.00700ZNF101+TRUEAluSc8SINE,Alu
chr2025428588AG0.00068GINS1+TRUEAluJbSINE,Alu
chr237328082TC1.18454E-08.FALSE
chr1474179051TC0.00982PNMA1-FALSECharlie15bSINE,Alu
chr357199227AC0.00638IL17RD-FALSE

Differential Expression Gene Analysis