Dataset Overview
RBPCPSF6
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR384BDV
PlatformHiSeq
Pubmed ID32252787

CPSF6 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of CPSF6
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of CPSF6


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr2217366919AG0.00709.FALSEAluSz6SINE,Alu
chr2206982255TC0.00431.FALSEAluSg7SINE,Alu
chr1155695998AG0.00574DAP3+TRUEAluSpSINE,Alu
chr344791062TC0.00035KIAA1143-FALSE
chr1113213004GT0.00206CAPZA1+FALSE
chr349315592TC0.00127USP4-FALSE
chr11668943AC0.00640SLC35E2-FALSE
chr1206516261CT0.00228SRGAP2+FALSE
chr192862896AG6.86172E-05.FALSEAluJrSINE,Alu
chr110517352TC0.00311.FALSEAluJrSINE,Alu
chr357613144TC0.00959DENND6A,PDE12+,-FALSEAluSzSINE,Alu
chr3189675266GT0.00781P3H2-FALSE(TG)nSINE,Alu
chr5137354051CT0.00098FAM13B-FALSE
chr1207942482AG0.00715CD46+TRUEAluSg4SINE,Alu
chr1929703961AC0.00376UQCRFS1-FALSE
chr126608016GA1.44245E-06.FALSE
chr237327662TC0.00022.FALSE
chr1532820880CG0.00672WHAMMP1-FALSE
chr136067811TC0.00439PSMB2-TRUEAluSzSINE,Alu
chr1234561498TC2.33971E-05TARBP1-FALSE
chr1120694990CA0.00325.FALSEA-richSINE,Alu
chr128661831AG9.37902E-09MED18+TRUEAluSgSINE,Alu
chr133149443AG0.00897SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1204524555AG1.07581E-05MDM4+TRUEAluYSINE,Alu
chr1075009579TC3.24788E-05DNAJC9-AS1,MRPS16+,-FALSEAluScSINE,Alu
chr2018469054TC0.00522RBBP9-TRUEAluJrSINE,Alu
chr2132481470CT0.00594C2orf27A+FALSE
chr237330534TC6.35640E-05.FALSEAluSq2SINE,Alu
chr147184569GC0.00027EFCAB14-FALSE
chr116928737CT0.00796NBPF1-FALSEERVL-E-intSINE,Alu
chr3196729939CT0.00862MELTF,MFI2-AS1+,-FALSEG-richSINE,Alu
chr138326704TC0.00328INPP5B-TRUEAluJrSINE,Alu
chr133071096AG0.00692ZBTB8A+TRUEAluSx1SINE,Alu
chr1149913727TC1.10479E-05OTUD7B-TRUEMER96BSINE,Alu
chr167875011GT0.00359SERBP1-FALSE
chr1184762524TC0.00471FAM129A-TRUEAluSzSINE,Alu
chr848890109AG8.88178E-16MCM4+TRUEAluJbSINE,Alu
chr167874705TC0.00015SERBP1-TRUEAluSx3SINE,Alu
chr1153520954CT0.00910LOC101928034,S100A3+,-FALSE
chr9132268957AG0.00316LINC00963+TRUEAluYf1SINE,Alu
chr5135513089TA7.47633E-06SMAD5+FALSE
chr399517483CT0.00070MIR548G-FALSE(TG)nSINE,Alu
chr122159774GA0.00257HSPG2-FALSE
chr186049363CT0.00064CYR61+FALSE
chr119542239TC0.00032LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr4185309396GA0.00199IRF2-FALSE(GGGAT)nSINE,Alu
chr110521237TC0.00200DFFA-TRUEAluYSINE,Alu
chr1464951277TC0.00077ZBTB25-TRUEAluSpSINE,Alu
chr7129472355GC0.00246UBE2H-FALSE
chr2204298783AC0.00179RAPH1-FALSE(AT)nSINE,Alu
chr119586520AG0.00305MRTO4+TRUEAluSzSINE,Alu
chr989626918AG0.00048LOC440173-FALSE
chr76442892CA0.00675RAC1+FALSE
chr5177019196GC0.00509TMED9+FALSE(GCG)nSINE,Alu
chr110521254TC0.00522DFFA-TRUEAluYSINE,Alu
chr16427820CT0.00240TMEM8A-FALSE
chr1990280CT0.00243AGRN+FALSE
chr1061548859AC0.00011CCDC6-FALSE
chr8100890376GT0.00920COX6C-FALSE
chr1148752615CA0.00042.FALSE
chr128825466AG0.00701PHACTR4+TRUEAluSgSINE,Alu
chr349396588TC0.00239RHOA-FALSE
chr238971643TA0.00013SRSF7-FALSE
chr2236677551TC7.06365E-05MYH9-FALSE
chr125775374CT0.00710TMEM57+FALSE
chr19165685GA7.66901E-05GPR157-FALSE
chr116889414TC0.00384NBPF1-TRUEL1MC4SINE,Alu
chr765618786AG3.58027E-08CRCP+TRUEAluSx3SINE,Alu
chr1100440563AG0.00732SLC35A3+FALSEAluJbSINE,Alu
chr2237035915CG0.00348AGAP1+FALSE
chr4119551832GA0.00522LOC729218+FALSE
chr116892275CT0.00230NBPF1-FALSE
chr2025428384AG0.00195GINS1+TRUEAluSzSINE,Alu
chr12133297961AG1.06136E-06PGAM5+TRUEAluJoSINE,Alu
chr1945406538CG0.00119TOMM40+FALSE
chr9139299673GC0.00710SDCCAG3-FALSE
chr2206983115TC0.00992.FALSEAluJbSINE,Alu
chr1224927968GA0.00695CNIH3+FALSE
chr110520378TC0.00047.FALSEAluSx1SINE,Alu
chr1320247038AG0.00391MPHOSPH8+TRUEAluJbSINE,Alu
chr286252112TC0.00233POLR1A-TRUEAluSq2SINE,Alu
chr19329289CT0.00303H6PD+FALSE
chr4177252238AG9.63526E-05SPCS3+TRUE
chr1921366997AG0.00727ZNF431+TRUEAluScSINE,Alu
chr1610623639TC0.00392EMP2-TRUEAluSpSINE,Alu
chr314986110TC0.00691FGD5-AS1-TRUEFLAM_CSINE,Alu
chr1168523338TC0.00817CPT1A-TRUEAluSqSINE,Alu
chr1773886219TC8.52474E-05TRIM65-TRUEFRAMSINE,Alu
chr237331275TC0.00884.FALSEAluSx1SINE,Alu
chr1919793876AG0.00080ZNF101+TRUEAluSc8SINE,Alu
chr136068275TC0.00048PSMB2-TRUEAluScSINE,Alu
chr210942687CT0.00082PDIA6-FALSE
chr2160084473AC0.00101TANC1+FALSE
chr13114748384CT0.00050RASA3-FALSE
chr7100031498TC0.00110MEPCE+FALSE
chr1234744480GA0.00409IRF2BP2-FALSE
chr167874859TC0.00374SERBP1-TRUEAluSxSINE,Alu
chr110520702TC0.00883DFFA-TRUEAluSc8SINE,Alu
chr133066960AG0.00079ZBTB8A+TRUEAluSq4SINE,Alu
chr5149823795AT0.00722RPS14-FALSE
chr1150548904AT0.00052MCL1-FALSE
chr398518160TA0.00197DCBLD2-FALSE
chr1060047609AG0.00979CISD1+FALSE(A)nSINE,Alu
chr165900357GT0.00851LEPR,LEPROT+FALSE
chr119542679TC1.36514E-06LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr1142660333GA8.80387E-05.FALSE
chr237327589TC0.00253.FALSE
chr2134728144AG2.75061E-05IFNAR1+TRUEAluScSINE,Alu
chr5121362874AG0.00022SRFBP1+TRUEFRAMSINE,Alu
chr10119038371CT0.00058SLC18A2+FALSE(ATTTGGCA)nSINE,Alu
chr11650832AG0.00241CDK11B,CDK11A-FALSE
chr1109818159GT0.00419CELSR2+FALSE
chr76501836AC0.00081KDELR2-FALSE
chr642045563AG4.21139E-05TAF8+TRUEAluSzSINE,Alu
chr3101579158AG0.00022NFKBIZ+FALSEAluJoSINE,Alu
chr579923424TC0.00054DHFR-TRUEAluJrSINE,Alu
chr1075009585TC2.45347E-10DNAJC9-AS1,MRPS16+,-FALSEAluScSINE,Alu
chr194352570GT0.00097GCLM-FALSEAluSx1SINE,Alu
chr233046027GC0.00397TTC27+FALSE
chr136388197CT0.00315AGO1+FALSE
chr286272758GA0.00023POLR1A-FALSE
chr127662666AG0.00799TMEM222+FALSE
chr261416411TG0.00146USP34-FALSEAluSc8SINE,Alu
chr314986137TC1.37684E-08FGD5-AS1-TRUEFLAM_CSINE,Alu
chr146827769CT0.00103NSUN4+FALSE
chr193603188AG0.00374MTF2+FALSE
chr126755229AG0.00318LIN28A+FALSEAluSx1SINE,Alu
chr1115119377AT0.00157BCAS2-FALSE
chr1144614931GA0.00469NBPF20+FALSE
chr3196660052GA0.00200SENP5+FALSEAluSzSINE,Alu
chr634254585GT0.00519.FALSEAluSq2SINE,Alu
chr12133298254AG0.00849PGAM5+TRUEAluSpSINE,Alu
chr18045340CA0.00056PARK7+FALSE
chr76370194CT0.00029FAM220A-FALSE
chr314985983AT6.81677E-14FGD5-AS1-FALSE
chr631324643GC5.95617E-06.FALSE
chr128800380CA0.00186PHACTR4+FALSE
chr1144594373CG0.00354NBPF20+FALSE
chr29770610AG0.00466YWHAQ-FALSE
chr549692280TC9.73531E-05EMB-FALSEL2cSINE,Alu
chr224225006AG0.00078.FALSEAluSxSINE,Alu
chr2242176182GA2.43141E-09HDLBP-FALSE
chr12125513788AG0.00592.FALSEAluSx1SINE,Alu
chr439551976TC0.00041UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr7100279005CA0.00176GIGYF1-FALSE(A)nSINE,Alu
chr126801736AT0.00578HMGN2+FALSE(T)nSINE,Alu
chr11595602AG9.14189E-05CDK11B,SLC35E2B-FALSEAluJrSINE,Alu
chr2217366897AG0.00440.FALSEAluSz6SINE,Alu
chr143629979GT0.00470EBNA1BP2-FALSE
chr175175797GA0.00203CRYZ-FALSE
chr1145689717AG0.00696NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr189447720GA0.00029KYAT3,RBMXL1-FALSE
chr5149823794GT0.00204RPS14-FALSE
chr596368471GT3.92809E-06.FALSE
chr3155572129CT0.00082SLC33A1-FALSE
chr1114306372AG0.00243RSBN1-FALSE
chr346623292TC0.00408TDGF1+FALSEAluSx3SINE,Alu
chr5115165731TC0.00410ATG12-TRUEAluSq2SINE,Alu
chr110221302GA0.00119UBE4B+FALSE
chr46718811AG1.36854E-07BLOC1S4+FALSEFLAM_ASINE,Alu
chr399515750AG0.00216MIR548G-FALSE
chr192426238TG0.00129TIMM13,TMPRSS9+,-FALSE
chr1215035081TC0.00951MGP-FALSE
chr1352327020GA0.00019WDFY2+FALSE
chr286252043TC0.00909POLR1A-TRUEAluSq2SINE,Alu
chr1120163247TC0.00365ZNF697-FALSE
chr145975498AG9.09033E-05MMACHC+TRUEAluSx4SINE,Alu
chr2127826533AG0.00104BIN1-FALSE
chr642856029AG7.18756E-05RPL7L1+TRUEAluSzSINE,Alu
chr116939857CT0.00542NBPF1-FALSE
chr2128064448GT0.00602MAP3K2-FALSE(GT)nSINE,Alu
chr2191799592AG0.00010GLS+TRUE
chr1156692054AT0.00471ISG20L2-FALSEAluYSINE,Alu
chr116577908GC0.00686FBXO42-FALSE
chr128836973AG0.00289SNHG3,RCC1+TRUEAluScSINE,Alu
chr1150704418TC0.00420CTSS-TRUEAluJoSINE,Alu
chr730544360GA0.00170GGCT-FALSE
chr1119683390GA0.00283LOC101929147+FALSE
chr5290324TA0.00729PDCD6+FALSE
chr119232017TG0.00519IFFO2-FALSE
chr3169810385CT0.00621PHC3-FALSE
chr11126147713CG0.00384FOXRED1+FALSE
chr333138549GA0.00612GLB1-FALSE
chr232539582AG0.00419.FALSEAluSpSINE,Alu
chr261152521GA0.00134REL+FALSE
chr1954627915CT0.00015PRPF31+FALSE
chr116893841CT0.00272NBPF1-FALSE
chr178483452CT0.00045DNAJB4+FALSEL1MB7SINE,Alu
chr136067784TC1.68158E-09PSMB2-TRUEAluSzSINE,Alu
chr3141667690TC0.00018TFDP2-TRUEAluYSINE,Alu
chr1150937961AC0.00060CERS2-FALSEG-richSINE,Alu
chr2174090636TA0.00043ZAK,MLK7-AS1+,-FALSE
chr168943486CT0.00079DEPDC1-FALSE(TTCTCTT)nSINE,Alu
chr110520532TC0.00142.FALSEAluSx1SINE,Alu
chr1179829595TC0.00188TOR1AIP2-TRUEAluJrSINE,Alu
chr153289892AG0.00070ZYG11B+TRUEFRAMSINE,Alu
chr187573327TC0.00571HS2ST1+FALSE(AT)nSINE,Alu
chr3196557357GT0.00615PAK2+FALSE
chr345721905AG0.00238LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr310192652AG0.00155VHL+TRUEAluSx1SINE,Alu
chr122854931CA0.00238ZBTB40+FALSEA-richSINE,Alu
chr3160969268CT0.00835NMD3+FALSE
chr532586387TC0.00569SUB1+FALSE
chr159246520AC7.56706E-05JUN-FALSE
chr193603196GA0.00627MTF2+FALSE
chr6158613390TC0.00416GTF2H5+FALSE
chr1322711AG0.00149.FALSE
chr398299365TG0.00133CPOX-FALSE
chr128566320TC0.00309.FALSEAluSx1SINE,Alu
chr1542192345TC0.00039EHD4-TRUE
chr1120539687TC0.00179NOTCH2-FALSE
chr233812352AG0.00223FAM98A-FALSE
chr11125526125AG0.00374CHEK1+TRUEFRAMSINE,Alu
chr1148252049AC0.00042NBPF8,NBPF14,NBPF9-FALSE
chr144171144TA0.00108KDM4A-AS1,KDM4A+,-FALSE
chr1181057874TG0.00099IER5+FALSE
chr1476045220TC0.00421LOC102724153,FLVCR2+,-FALSE
chr119542305TC0.00085LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr116889575TC0.00969NBPF1-TRUE
chr1619513719TA0.00730GDE1-FALSEAluJrSINE,Alu
chr1953997266AG0.00173ZNF813+FALSEL1M3SINE,Alu
chr112677547GA0.00543DHRS3-FALSE(A)nSINE,Alu
chr133087433CT0.00687ZBTB8OS-FALSE
chr315113783TC0.00127RBSN-FALSEAluSz6SINE,Alu
chr2201774209TC0.00534.FALSEAluSzSINE,Alu
chr116889864CA0.00598NBPF1-FALSE
chr274090064AT0.00197STAMBP+FALSE
chr1728963296AG0.00572LOC107133515+TRUEAluJr4SINE,Alu
chr286249961TC0.00292LOC90784-TRUEAluJrSINE,Alu
chr140759231AG0.00168ZMPSTE24+FALSE
chr1165544575TC0.00200AP5B1-TRUEAluJbSINE,Alu
chr1757279258AG0.00095PRR11+TRUEAluSq2SINE,Alu
chr2202031433AG0.00611CFLAR+FALSESVA_ASINE,Alu
chr1328240417CG6.17934E-05POLR1D+FALSE
chr126755643AG0.00068LIN28A+FALSEAluScSINE,Alu
chr765844562TC0.00695LINC00174-FALSE
chr61395043TC0.00055FOXF2+FALSE
chr19161137TC0.00087.FALSEAluSxSINE,Alu
chr177166017GA0.00627.FALSE
chr1165877575AC0.00675UCK2+FALSE
chr178029102GA0.00086ZZZ3-FALSE
chr116918783CT0.00252NBPF1-FALSE
chr1109605647GA0.00019.FALSEAluYSINE,Alu
chr339452772AG0.00127RPSA+FALSE
chr1681064611AG0.00075CENPN+TRUEAluSgSINE,Alu
chr115668319GA0.00489FHAD1+FALSE
chr63021360TC0.00321HTATSF1P2-TRUEAluJr4SINE,Alu
chr1918476232AG0.00189PGPEP1+TRUEAluJbSINE,Alu
chr142008521GT0.00882HIVEP3-FALSE
chr8124262075GT7.79989E-05ZHX1-C8orf76,ZHX1-FALSE
chr1116943511TC0.00236ATP1A1,ATP1A1-AS1+,-FALSE
chr152375424TC0.00109RAB3B-FALSE
chr1939874945TC0.00335SAMD4B+FALSE
chr579923912TC0.00037DHFR-TRUEAluSpSINE,Alu
chr1154987526CT0.00043ZBTB7B+FALSE
chr439550978TC0.00023UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr1675479474TC2.06057E-06TMEM170A-TRUEAluJbSINE,Alu
chr1541593352AG0.00083.FALSEAluSz6SINE,Alu
chr11252513TC0.00043CPSF3L-TRUEAluSpSINE,Alu
chr191457883CG2.74690E-05APC2+FALSE
chr3195243007AC3.91570E-06PPP1R2-FALSE
chr457326315AG0.00025PAICS+TRUEAluJrSINE,Alu
chr3112299732AG0.00189SLC35A5+FALSE
chr119586458AG1.61978E-09MRTO4+TRUEAluSzSINE,Alu
chr1475202857AG2.23354E-05FCF1+TRUEAluSxSINE,Alu
chr11344757AG0.00024.FALSEAluSx1SINE,Alu
chr1206580084CG0.00104SRGAP2+FALSE
chr1541591021AG0.00427OIP5-AS1+TRUEAluSx1SINE,Alu
chr417802956TC0.00351DCAF16-TRUEAluSzSINE,Alu
chr1179829508TC0.00048TOR1AIP2-TRUEAluJrSINE,Alu
chr1185069687CT0.00072RNF2+FALSE
chr5149829068CT0.00038RPS14-FALSE
chr19328255AG0.00729H6PD+TRUEAluJrSINE,Alu
chr38922054TC0.00300RAD18-FALSE
chr74809333AG0.00067FOXK1+TRUEAluSx1SINE,Alu
chr110041422AG0.00115NMNAT1+TRUEAluYj4SINE,Alu
chr237328034TC6.77479E-07.FALSE
chr19161668TC0.00456.FALSE
chr19160975TC0.00858.FALSEAluJbSINE,Alu
chr116893686GC0.00171NBPF1-FALSE
chr11252441TC0.00602CPSF3L-TRUEAluJrSINE,Alu
chr19643195AG0.00294.FALSEAluSxSINE,Alu
chr132697085TC0.00366EIF3I+FALSEAluSpSINE,Alu
chr1144852167GT0.00352NBPF20,PDE4DIP+,-FALSE
chr1145512024AG0.00247NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1184761350TC0.00219FAM129A-TRUEAluJoSINE,Alu
chr124296856TG0.00564.FALSEAluSgSINE,Alu
chr1610625300TC0.00178EMP2-TRUEAluSxSINE,Alu
chr373116347TA0.00109PPP4R2+FALSE
chr1209602381GA0.00075MIR205HG+FALSEAluJbSINE,Alu
chr579923788TC0.00693DHFR-TRUEAluSpSINE,Alu
chr2175711942CT8.43847E-05CHN1-FALSE
chr1155838369GC0.00346SYT11+FALSE
chr540832557GT5.89786E-05RPL37-FALSE
chr812286573GA0.00052FAM86B2-FALSE

Differential Expression Gene Analysis