Dataset Overview
RBPNONO
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR398HXV
PlatformHiSeq
Pubmed ID32252787

NONO - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of NONO
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of NONO


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr348632596AG0.00666.FALSE
chr1144833382CT0.00325NBPF20+FALSEL1MEcSINE,Alu
chr596110613TA0.00993ERAP1-FALSE
chr153289686AG0.00029ZYG11B+TRUEAluSzSINE,Alu
chr2162268108GA0.00091PSMD14+FALSE
chr10104417853TA0.00393TRIM8+FALSE(AAT)nSINE,Alu
chr1590820104AG4.84304E-05.FALSEAluYSINE,Alu
chr1145512073AG0.00131NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr285775237TC6.42894E-05GGCX-TRUEAluSx4SINE,Alu
chr1738974612TC0.00963KRT10-FALSE
chr128826128AG0.00060PHACTR4+TRUEAluJbSINE,Alu
chr5150827303TG0.00718SLC36A1+FALSE
chr10117823568TA0.00483GFRA1-FALSE(ATC)nSINE,Alu
chr1176176230GA0.00091RFWD2-FALSE
chr393780109GC8.09346E-05DHFR2-FALSE
chr174856580TC0.00922ENO3+FALSE
chr1201488771AG0.00062.FALSEAluSq2SINE,Alu
chr261277463AG0.00826PEX13+TRUEAluSxSINE,Alu
chr1180943529CT0.00297STX6-FALSE
chr1298943162AG5.01524E-05TMPO+TRUEAluSzSINE,Alu
chr323958355CT0.00997NKIRAS1,RPL15+,-FALSE
chr3179506482AG0.00017USP13+FALSEMER33SINE,Alu
chr2200792307GA0.00596C2orf69+FALSE
chr1900717CT0.00661KLHL17+FALSE(TTTA)nSINE,Alu
chr153288924AG0.00099ZYG11B+TRUEAluJoSINE,Alu
chr42940098TC0.00034NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr5125962169AG0.00013PHAX+TRUEAluScSINE,Alu
chr1150190851GT0.00339ANP32E-FALSE
chr1145512078AG0.00907NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr19328213AG0.00404H6PD+TRUEAluJrSINE,Alu
chr6166824706AT0.00048RPS6KA2-FALSE(T)nSINE,Alu
chr1298942808AG0.00019TMPO+TRUEAluScSINE,Alu
chr18045340CA0.00056PARK7+FALSE
chr154493197TC0.00064TMEM59-TRUEAluSz6SINE,Alu
chr438016395TG0.00537TBC1D1+FALSE
chr347036756CG0.00091NBEAL2+FALSE
chr167874689TC0.00146SERBP1-TRUEAluSx3SINE,Alu
chr49909923GA0.00416SLC2A9-FALSE
chr237327590TC0.00681.FALSE
chr4843695AG0.00602GAK-FALSE
chr140539208AT2.90582E-07PPT1-FALSE
chr135319605AC0.00226SMIM12-FALSEAluSgSINE,Alu
chr117394775GA0.00103PADI2-FALSE
chr1101354038TC0.00565EXTL2-TRUEL1MB2SINE,Alu
chr153289686AG0.00063ZYG11B+TRUEAluSzSINE,Alu
chr1144932220GT0.00449NBPF20,PDE4DIP+,-FALSE
chr16583457TC0.00233NOL9-TRUEAluSqSINE,Alu
chr110517313TC0.00015.FALSEAluJrSINE,Alu
chr12133298025AG6.18330E-06PGAM5+TRUEAluJoSINE,Alu
chr127434251GA0.00504SLC9A1-FALSE
chr457326315AG0.00281PAICS+TRUEAluJrSINE,Alu
chr119542456TC0.00135LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr116921146TC0.00353NBPF1-FALSE
chr1099504630GT0.00544ZFYVE27+FALSE
chr273301687GA0.00618RAB11FIP5-FALSE
chr8146200271TC0.00182ZNF252P-TRUEAluScSINE,Alu
chr2217123958TC0.00012MARCH4-FALSE
chr1179044206AG0.00458FAM20B+TRUEAluSxSINE,Alu
chr237331745TC0.00097.FALSEAluJbSINE,Alu
chr124289896TG0.00051PNRC2+FALSE
chr1201846635AT0.00293IPO9+FALSE(CA)nSINE,Alu
chr16283305TC0.00129ICMT-TRUEAluSx3SINE,Alu
chr1109465167TA0.00233GPSM2+FALSE
chr4128958127AG0.00556ABHD18+TRUEAluSx3SINE,Alu
chr531553968TC0.00555C5orf22+FALSE
chrX23721458TA0.00413.FALSEAluSc8SINE,Alu
chr12125269489CT0.00817SCARB1-FALSE
chr2206984202TC0.00849.FALSEAluSxSINE,Alu
chr296915238TC2.48142E-05.FALSEAluJrSINE,Alu
chr16583109TC6.65543E-05NOL9-TRUEAluSx4SINE,Alu
chr116945409TA0.00290CROCCP2-FALSE
chr363996262CT0.00273PSMD6-AS2,PSMD6+,-FALSE
chr2220308581AC0.00029SPEG+FALSE
chr1230416038GA0.00626GALNT2+FALSE
chr285776765TC0.00426GGCX-TRUEAluSz6SINE,Alu
chr116529004AC3.00007E-07ARHGEF19-FALSE
chr191486839TC0.00329ZNF644-FALSE
chr127876482CA0.00687AHDC1-FALSE
chr5115165591TC0.00407ATG12-TRUEAluSq2SINE,Alu
chr138174366GT0.00879CDCA8+FALSE
chr135650162CA0.00106SFPQ-FALSE
chr2206986314TC0.00936.FALSEAluSzSINE,Alu
chr1201438095CG3.49736E-05PHLDA3-FALSE
chr1148595665AG0.00378NBPF15+TRUEL1MC4SINE,Alu
chr1541590999AG0.00049OIP5-AS1+TRUEAluSx1SINE,Alu
chr110519912TC0.00185.FALSEAluJrSINE,Alu
chr535058804AT0.00836PRLR-FALSE
chr110520378TC0.00145.FALSEAluSx1SINE,Alu
chr456291623GT0.00490TMEM165+FALSE
chr596366330GC0.00251.FALSE(TG)nSINE,Alu
chr140361783GC0.00023MYCL-FALSE
chr210567337GC0.00940HPCAL1+FALSE
chr11337734CT3.46713E-05MRPL20-FALSE
chr841399823AG0.00172LOC102723729,GINS4+,-FALSEAluSx3SINE,Alu
chr1674655591TG0.00652RFWD3-FALSEAluSxSINE,Alu
chr133147947AG0.00345SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr1585184841TC0.00016WDR73,SCAND2P+,-FALSEAluSzSINE,Alu
chr153679610GA0.00217CPT2+FALSEAluSzSINE,Alu
chr827661035TA0.00314ESCO2+FALSEA-richSINE,Alu
chr314175262TC3.06250E-10TMEM43+FALSE
chr1919793729AG0.00124ZNF101+TRUEAluSc8SINE,Alu
chr1540954864AG0.00636KNL1+TRUE
chr484525974TC0.00255GPAT3+FALSE(TTGTT)nSINE,Alu
chr2239972080TA0.00136HDAC4-FALSE
chr13731959CT0.00089CEP104-FALSE
chr136386884CT0.00024AGO1+FALSE
chr119934679GA0.00354MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr345721874AG0.00314LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr116933625AG0.00536NBPF1-FALSEGA-richSINE,Alu
chr1681744038TC6.34278E-05CMIP+FALSE(CCGC)nSINE,Alu
chr1114306372AG0.00443RSBN1-FALSE
chr110520684TC0.00125DFFA-TRUEAluSc8SINE,Alu
chr577655330TC0.00050SCAMP1-AS1-TRUEAluSx4SINE,Alu
chr5118173627TC0.00075DTWD2-TRUE
chr2132481526CA0.00040C2orf27A+FALSE
chr1939433138GA0.00276FBXO17-FALSEAluJbSINE,Alu
chr111084103TA0.00162TARDBP+FALSE
chr19161011TC0.00190.FALSEAluJbSINE,Alu
chr14103372464CA0.00577TRAF3+FALSE(AC)nSINE,Alu
chr237331207TC0.00745.FALSEAluSx1SINE,Alu
chr237429626AG0.00385CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr417804847TC0.00512DCAF16-TRUEAluSxSINE,Alu
chr168902411AG0.00357PMM2+FALSE
chr3189713205TC4.97145E-05P3H2-FALSE
chr42940397TC0.00010NOP14-AS1,NOP14+,-FALSEAluJoSINE,Alu
chr581571878AT8.61300E-05RPS23-FALSE
chr119543459TC0.00395LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr10104417856TA0.00616TRIM8+FALSE(AAT)nSINE,Alu
chr132372360CT0.00697PTP4A2-FALSE(CA)nSINE,Alu
chr1222802926CT0.00035MIA3+FALSE
chr2217366901AG0.00143.FALSEAluSz6SINE,Alu
chr2191067763AT0.00038C2orf88+FALSE
chr136068231TC0.00508PSMB2-TRUEAluScSINE,Alu
chr579923361TC0.00050DHFR-TRUEAluJrSINE,Alu
chr191457883CG2.74690E-05APC2+FALSE
chr275887834TC0.00024MRPL19+FALSEL1MB4SINE,Alu
chr111084345CT0.00558TARDBP+FALSE
chr116932783GC0.00843NBPF1-FALSEL1MC2SINE,Alu
chr19161011TC7.97270E-05.FALSEAluJbSINE,Alu
chr1590375419TC0.00521C15orf38-AP3S2,AP3S2-TRUEAluJrSINE,Alu
chr1220231254TC0.00974RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr115899630TC0.00082AGMAT-TRUEAluSq2SINE,Alu
chr1203771852GT0.00883ZC3H11A+FALSE(T)nSINE,Alu
chr5175802154CT0.00883.FALSE(CATC)nSINE,Alu
chr3139086995CA0.00743COPB2-FALSE
chr1773885274TC0.00143TRIM65-TRUEAluSgSINE,Alu
chr1155032752AG0.00347LOC100505666,ADAM15+,-FALSE
chr4169911112CA0.00142CBR4-FALSE
chr132508397TC0.00166KHDRBS1+FALSE
chr1161088583TG0.00822NIT1+FALSE
chr1253435276TG4.45732E-05EIF4B+FALSE
chr140214261AG0.00879PPIE+TRUEAluSq2SINE,Alu
chr237331221TC1.68149E-05.FALSEAluSx1SINE,Alu
chr1120839683GA0.00875FAM72B+FALSE
chr7107788257CT0.00068NRCAM-FALSE
chr3191114309AT1.88175E-05CCDC50+FALSE
chr110519936TC0.00349.FALSEAluJrSINE,Alu
chr613789467TC0.00019MCUR1-TRUEAluSgSINE,Alu
chr151820588GA0.00807EPS15-FALSE
chr12100562932GT0.00079GOLGA2P5-FALSEAluSgSINE,Alu
chr110520153TC0.00398.FALSEAluSxSINE,Alu
chr110520117TC0.00078.FALSEAluSxSINE,Alu
chr128261657CT0.00327SMPDL3B+FALSE
chr1743248581CT0.00012LOC105371795-FALSE
chr217965699CT0.00497GEN1+FALSEL1M4SINE,Alu
chr133149363AG0.00237SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr127107948GA0.00177ARID1A+FALSE
chr19910358TC0.00083CTNNBIP1-FALSE
chr194335333GT0.00258DNTTIP2-FALSE
chr11595048TC0.00495CDK11B,SLC35E2B-TRUEAluSgSINE,Alu
chr6116600810GA0.00028DSE,TSPYL1+,-FALSE
chr116890130AC0.00728NBPF1-FALSE
chr5122165512CA0.00276SNX2+FALSE
chr133148211AG9.09328E-07SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr540830050TC0.00042.FALSEAluSpSINE,Alu
chr154691921GA0.00909SSBP3-FALSE
chr373115126AT0.00228PPP4R2+FALSE
chr132374019GA0.00297PTP4A2-FALSE
chr145452227GC0.00279EIF2B3-FALSE
chr652267967AC0.00424PAQR8+FALSE
chr534906156TC2.52494E-05RAD1-TRUEAluSx1SINE,Alu
chr1214524044TC0.00242PTPN14-TRUEAluSxSINE,Alu
chr315113885TC0.00094RBSN-TRUEAluSz6SINE,Alu
chr1229795330TC0.00334URB2+FALSE
chr160340527GA0.00027HOOK1+FALSE
chr145975269AG0.00827MMACHC+TRUEAluSg7SINE,Alu
chr163881552CT0.00293ALG6+FALSE
chr145975345AG0.00614MMACHC+TRUEAluSg7SINE,Alu
chr189447715TG0.00137KYAT3,RBMXL1-FALSE
chr116200163AG0.00078SPEN+FALSE
chr1327441AG1.08612E-09.FALSE
chr12125114CT1.71441E-12FAAP20-FALSE
chr1205719141CT0.00021NUCKS1-FALSE
chr12125512540AG7.43833E-09.FALSE
chr4103809241AT0.00073CISD2,SLC9B1+,-FALSE
chr225962254AT0.00375ASXL2-FALSE
chr127205359TC0.00301.FALSEAluScSINE,Alu
chr1145284138GA0.00382NBPF20,NOTCH2NL+FALSE(TG)nSINE,Alu
chr1209605640AC0.00581MIR205HG+FALSE(AGC)nSINE,Alu
chr1217688165CA0.00343GPATCH2-FALSE
chr7100804140CT0.00377AP1S1+FALSE
chr3172115474AG0.00012FNDC3B+FALSE(A)nSINE,Alu
chr1749041866TC0.00153SPAG9-TRUEAluSxSINE,Alu
chr629912348AG0.00429.FALSE
chr128661576AG0.00625MED18+TRUEAluSgSINE,Alu
chr6158517308AG0.00959SYNJ2+FALSE
chr1163309219AT0.00023NUF2+FALSE
chr1165404866TG0.00664PCNX3+FALSE(T)nSINE,Alu

Differential Expression Gene Analysis