Dataset Overview
RBPLMNB1
Knock-MethodsiRNA
RBP FamilyNon-canonical_RBP
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR656ZOI
PlatformHiSeq
Pubmed ID32252787

LMNB1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of LMNB1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of LMNB1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr320025661CT4.83976E-05RAB5A,PP2D1+,-FALSE
chr1184675814GA0.00730EDEM3-FALSE
chr1117530217CT0.00048PTGFRN+FALSE
chr2191745652AT1.16463E-05GLS+FALSE
chr1148189152AC0.00050PTPRJ+FALSE
chr110520819TC0.00022DFFA-TRUEAluSc8SINE,Alu
chr772480095AG0.00590PMS2P2+FALSE
chr3172117457CA0.00037FNDC3B+FALSE
chr144818525TC0.00235ERI3-FALSE
chr1214524566TC0.00040PTPN14-TRUEAluSgSINE,Alu
chr1193054574GT0.00511TROVE2+FALSE(ATTTT)nSINE,Alu
chr1101541172AG6.48917E-05LOC102606465+TRUEMLT1KSINE,Alu
chr5179048449TG0.00394HNRNPH1-FALSE
chr439528976CT8.52335E-05UGDH-FALSE
chr5175802154CT0.00883.FALSE(CATC)nSINE,Alu
chr123381596TC0.00762KDM1A+FALSE
chrX152916230AC1.62471E-05DUSP9+FALSE
chr717384437AG0.00192AHR+TRUEAluSxSINE,Alu
chr1024873171GT0.00329ARHGAP21-FALSE
chr136068369TC5.31121E-05PSMB2-TRUEAluScSINE,Alu
chr674493432AC0.00611CD109+FALSE
chr3194789330GT0.00150XXYLT1-FALSEAluJrSINE,Alu
chr178414285TA0.00179FUBP1-FALSE
chr823049112TC0.00774TNFRSF10A-TRUE
chr1150621090GA0.00212GOLPH3L-FALSE
chr6143382538AT0.00145AIG1+FALSE
chr237330172TG0.00972.FALSE
chr1666765441GT4.44089E-16DYNC1LI2-FALSEL2cSINE,Alu
chr1144821900CG6.24876E-05NBPF20,NBPF9+FALSE
chr193297607CT0.00016RPL5+FALSE
chr1757281021AG1.37320E-05PRR11+TRUEAluSzSINE,Alu
chr3179117242TC0.00011GNB4-TRUEAluSzSINE,Alu
chr1725640295TA0.00154WSB1+FALSE
chr145187511TC7.71832E-06C1orf228+FALSEU5SINE,Alu
chr11653046TA0.00686CDK11B,CDK11A-FALSE
chr5134086670CA0.00585CAMLG+FALSE
chr744841646AC0.00316PPIA+FALSEAluJrSINE,Alu
chrX135300092TC0.00075MAP7D3-TRUEAluSzSINE,Alu
chr163924020CT0.00139ITGB3BP-FALSE
chr537290504TC0.00410.FALSEAluSzSINE,Alu
chr1475202722AG0.00022FCF1+TRUEAluScSINE,Alu
chr1200375418CT0.00671ZNF281-FALSE
chr2238678002CG0.00711LRRFIP1+FALSE
chr310191943GA2.29886E-07VHL+FALSE
chr139470978TA0.00378AKIRIN1+FALSEAluSx1SINE,Alu
chr299812978AG0.00475MRPL30+TRUEAluJbSINE,Alu
chr6150046734TC0.00248NUP43-FALSE
chr190152146CT1.61967E-05LRRC8C+FALSE
chr16283264TC0.00287ICMT-TRUEAluSx3SINE,Alu
chr1542860120AG0.00045HAUS2+TRUEAluSgSINE,Alu
chr2112252464GA2.95640E-06MIR4435-2HG-FALSE
chr3197611262AG0.00208.FALSEAluSx1SINE,Alu
chr1156262653AC0.00128GLMP-FALSE
chr168168152CT0.00258GNG12-FALSE
chr16314171GA0.00855GPR153-FALSE
chr138423183CT0.00210SF3A3-FALSEAluJoSINE,Alu
chr3195411991CA0.00058SDHAP2+FALSE
chr1154128838GT0.00062TPM3-FALSE
chr132638906CT4.63739E-10KPNA6+FALSE
chr119585553AG0.00558MRTO4+TRUEAluSc8SINE,Alu
chr129395329GA0.00814LINC00987+FALSE
chr238971642GC0.00013SRSF7-FALSE
chr1100549600GT0.00181SASS6-FALSE
chr274333231CT0.00073TET3+FALSE
chr1688891240CA0.00826GALNS-FALSE
chr1298943149AG0.00019TMPO+TRUEAluSzSINE,Alu
chr1144828683CG3.91144E-05NBPF20,NBPF9+FALSE
chr1233518885TC0.00021MLK4+FALSE(TTTC)nSINE,Alu
chr642048297AG0.00307TAF8+TRUEAluSq2SINE,Alu
chr116945504CT0.00995CROCCP2-FALSE
chr18045340CA0.00217PARK7+FALSE
chr1681064543AG0.00066CENPN+TRUEAluSgSINE,Alu
chr5122359494GC0.00043PPIC-FALSE
chr3195415462GA0.00140LINC00969,SDHAP2+FALSE
chr1924104040AG0.00476ZNF726+TRUEAluSg4SINE,Alu
chr1949608GA0.00435ISG15+FALSE
chr274442407AG0.00384MTHFD2+FALSE
chr340578815AG0.00041ZNF621+FALSEAluJrSINE,Alu
chr186815303TC0.00571ODF2L-FALSE
chr8145159712AG0.00402MAF1+FALSE
chr136068231TC0.00022PSMB2-TRUEAluScSINE,Alu
chr1110950295CA0.00359LAMTOR5-FALSE
chr1229586611TC0.00794NUP133-TRUEAluSzSINE,Alu
chr3167727417CT2.31470E-08GOLIM4-FALSE
chr4187509420GA0.00121FAT1-FALSE
chr348787219AG0.00024PRKAR2A-FALSE
chr1051612914TC0.00063TIMM23B,TIMM23+,-FALSE
chr1148558269AG0.00538NBPF15+FALSEAluJbSINE,Alu
chr537289051TC0.00014.FALSEAluSpSINE,Alu
chr525415881TC0.00911.FALSE
chr5128430757TC0.00338ISOC1+FALSE
chr1109476780CT0.00990GPSM2,CLCC1+,-FALSE
chr310168785TC0.00198BRK1+FALSE
chr110520045TC0.00085.FALSEAluSxSINE,Alu
chr192946618AG0.00062GFI1-FALSE
chr126755643AG0.00728LIN28A+FALSEAluScSINE,Alu
chr126449327AG0.00330PDIK1L+FALSE
chr210586899GA0.00312ODC1,SNORA80B-FALSE
chr765844062TA0.00733LINC00174-FALSE
chr128566320TC0.00309.FALSEAluSx1SINE,Alu
chr124086786AC0.00812TCEB3+FALSE
chr110318652CG0.00047KIF1B+FALSE
chr255516940AC0.00389CCDC88A-FALSE(GA)nSINE,Alu
chr133149363AG0.00237SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1148003752TC3.77288E-10NBPF8-TRUEL1MC4SINE,Alu
chr1143399383TA0.00198.FALSEL1MC4SINE,Alu
chr517276088CA0.00171BASP1+FALSE(TC)nSINE,Alu
chr116890320TC0.00045NBPF1-FALSE
chr1146495576GC0.00107LOC728989-FALSE
chr9136209400AG0.00328MED22-FALSE
chr5174956493TA0.00466SFXN1+FALSE
chr119585553AG4.91829E-14MRTO4+TRUEAluSc8SINE,Alu
chr1542550445TC0.00360TMEM87A-FALSE
chr164125439AC3.63698E-07PGM1+FALSE
chr565453894TA0.00211SREK1+FALSE
chr42940147TC0.00061NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr152520864AT0.00041TXNDC12-FALSE
chr1145368461AC0.00542NBPF20,NBPF10+FALSE
chr132096265AG0.00208PEF1-FALSE
chr122419434TG0.00649CDC42+FALSE
chr170904800GT0.00020CTH+FALSE
chr310192717AG3.16601E-05VHL+TRUEAluSx1SINE,Alu
chr1742877749TC0.00287GJC1-TRUEAluSgSINE,Alu
chr3179116220TC0.00233GNB4-TRUEAluSz6SINE,Alu
chr136770601GT0.00055THRAP3+FALSE(T)nSINE,Alu
chr7128142395AC0.00300METTL2B+FALSE
chr133149443AG2.90388E-05SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1911257644TC0.00991SPC24-TRUEAluSpSINE,Alu
chr116918783CT0.00252NBPF1-FALSE
chr153289892AG0.00079ZYG11B+TRUEFRAMSINE,Alu
chr116946336GA0.00409CROCCP2-FALSE
chr165900357GT0.00851LEPR,LEPROT+FALSE
chr1157044418GC0.00707.FALSE
chr1075534488CT0.00025FUT11+FALSE
chr151873951GA0.00591EPS15-FALSE
chr310192747AG0.00893VHL+TRUEAluSx1SINE,Alu
chr3100084203CG0.00484TOMM70-FALSE
chr1254634283TC0.00047CBX5-TRUEAluJrSINE,Alu
chr128825331AG0.00563PHACTR4+TRUEAluSgSINE,Alu
chr16583270CG0.00026NOL9-FALSE
chr76501829TA0.00124KDELR2-FALSE
chr19324451CT0.00266H6PD+FALSE
chr133148045AG0.00264SYNC,RBBP4+,-FALSEAluSxSINE,Alu
chr261764916AC0.00189XPO1-FALSE(AC)nSINE,Alu
chr848890293AG0.00125MCM4+TRUEAluJbSINE,Alu
chr13545199GC0.00188TPRG1L+FALSE
chr9136209404GA0.00361MED22-FALSE(CAGGG)nSINE,Alu
chr273460316GT0.00368PRADC1-FALSE(CGGCGC)nSINE,Alu
chr121102502CA0.00021HP1BP3-FALSE
chr1162497663GA0.00365UHMK1+FALSE
chr7135291501TC0.00627NUP205+FALSE
chr133148213AG0.00958SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1179042482AG1.77761E-07FAM20B+TRUEAluSx1SINE,Alu
chr1109856378CA0.00804SORT1-FALSE
chr1118166096CT0.00861FAM46C+FALSE
chr1150937771TA0.00026CERS2-FALSE(ATTTTTT)nSINE,Alu
chr1164084160CT0.00895ESRRA,TRMT112+,-FALSE
chr1120163247TC0.00365ZNF697-FALSE
chr199673113TC0.00330.FALSEAluSx3SINE,Alu
chr15102516512GA0.00041WASH3P+FALSE
chr488059194CT0.00681AFF1+FALSE
chr116926980TC0.00062NBPF1-FALSE
chr127107650TA3.71504E-05ARID1A+FALSE
chr237872508GA5.12140E-05CDC42EP3-FALSE
chr143629979GT0.00470EBNA1BP2-FALSE
chr136068210TC0.00812PSMB2-TRUEAluScSINE,Alu
chr138174987TC0.00032CDCA8+FALSE
chr1117531179GA0.00116PTGFRN+FALSE
chr2113289701TG0.00994TTL+FALSE
chr269688754TC0.00319AAK1-TRUEAluSq2SINE,Alu
chr1470838369TC0.00015SYNJ2BP-COX16,SYNJ2BP-TRUEAluSgSINE,Alu
chr333430398TA0.00025UBP1-FALSE
chr9108152702GA2.83018E-05SLC44A1+FALSE
chr1179811337CA0.00670TOR1AIP2-FALSEAluSpSINE,Alu
chr3155660873AG0.00018.FALSEAluSzSINE,Alu
chr246852033AG0.00543CRIPT+FALSE
chrX16781156AG0.00061.FALSEAluJoSINE,Alu
chr136522460AG0.00407.FALSEAluScSINE,Alu
chr12106460001GA2.23324E-05NUAK1-FALSE
chr128661576AG0.00021MED18+TRUEAluSgSINE,Alu
chr261764922GC0.00679XPO1-FALSE
chr232447868AG0.00663SLC30A6+FALSE
chr644417136AG0.00644CDC5L+TRUEFLAM_CSINE,Alu
chr133086876TC0.00672ZBTB8OS-TRUEAluYSINE,Alu
chr110519932TC0.00547.FALSEAluJrSINE,Alu
chr116889414TC0.00384NBPF1-TRUEL1MC4SINE,Alu
chr10124815149CG0.00993ACADSB+FALSETHE1A-intSINE,Alu
chr287821033CA0.00474.FALSE
chr103208557AG0.00128PITRM1-FALSE
chr276672504AG2.97414E-06.FALSE7SKSINE,Alu
chr1109535128GA0.00063WDR47-FALSE
chr121810693AG0.00370NBPF3+FALSEL1MC4SINE,Alu
chr3101399945AG0.00965RPL24-FALSE
chr310193358AG0.00317VHL+TRUEL1ME4aSINE,Alu
chr1145369556AG0.00061NBPF20,NBPF10+TRUEL1MC4SINE,Alu
chr136770073AT4.33965E-05THRAP3+FALSE
chr5130537761AG0.00126LYRM7+FALSEAluJbSINE,Alu
chr13729587AG0.00580CEP104-FALSE(AT)nSINE,Alu
chr7129251289CT0.00808.FALSE
chr159122056GC1.57132E-06MYSM1-FALSE
chr146075187AC0.00024NASP+FALSEA-richSINE,Alu
chr11650832AG0.00241CDK11B,CDK11A-FALSE
chr237431604AG0.00876CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr1145688664AT0.00081NBPF20,NBPF10,RNF115+FALSE
chr1667715404TC0.00102GFOD2-TRUEAluSzSINE,Alu
chr171486543GC0.00452SLC43A2-FALSE
chr1154128827AT0.00724TPM3-FALSE
chr310192826AG0.00037VHL+TRUEAluSx1SINE,Alu
chr1765334726TC7.47982E-07PSMD12-TRUEAluSqSINE,Alu
chr1144594170CT0.00636NBPF20+FALSE
chr611577085CT1.34362E-05TMEM170B+FALSE
chr211323108TA0.00100ROCK2-FALSE(TA)nSINE,Alu
chr1541591457AG1.25234E-05OIP5-AS1+TRUEAluSxSINE,Alu
chr4152020780CT0.00925RPS3A+FALSE
chr1933470874AG0.00119RHPN2-FALSE
chr2203741032TC0.00282.FALSEAluJrSINE,Alu
chr228002599TA0.00566MRPL33+FALSE
chr3195411239AC5.03065E-05SDHAP2+FALSE
chr110043043AG0.00529NMNAT1+TRUEAluScSINE,Alu
chr199164434GA0.00309SNX7+FALSE
chr119585207GA0.00672MRTO4+FALSE
chrX77083939TC5.71267E-05MAGT1-TRUEAluSzSINE,Alu
chr348787052TC0.00866PRKAR2A-TRUEAluSx3SINE,Alu
chr165696034GC0.00803AK4+FALSE
chr187328400CT0.00755SEP15-FALSE
chr123636452AG0.00294HNRNPR-FALSE
chr1256510696AT0.00767RPL41+FALSE
chr1214529170TC0.00670PTPN14-TRUE
chr42940098TC0.00034NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr116889639TC0.00350NBPF1-TRUE
chr110041432AG0.00132NMNAT1+TRUEAluYj4SINE,Alu
chr314526653GT0.00936SLC6A6+FALSE
chr128864435AG0.00088RCC1+FALSE

Differential Expression Gene Analysis