Dataset Overview
RBP
EEF2
Knock-Method
shRNA
RBP Family
GTP_EFTU
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR477TRX
Platform
HiSeq
Pubmed ID
32252787
EEF2 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of EEF2
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
8.64
12.84
0.34754
0.00679
0.01565
A1CF
29.82
44.66
0.67650
3.09167E-13
4.51559E-12
A2M-AS1
0.37
0.68
0.84718
0.03533
0.06597
AAAS
30.03
37.97
0.26949
0.00539
0.01277
AADAC
0.56
2.09
1.68708
1.38925E-07
8.50939E-07
AADAT
7.03
8.29
0.29172
0.03950
0.07269
AAED1
5.35
5.25
-0.46912
0.00031
0.00098
AAK1
3.2
5.36
0.57120
2.86824E-05
0.00012
AAMP
132.44
113.93
-0.27770
0.00182
0.00487
AARS
50.74
40.8
-0.32956
0.00248
0.00641
Showing 1 to 10 of 7,547 entries
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Function Analysis of Target Genes of EEF2
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AFP
74320952_74321007_74319481_74319614_74321347_74321891
0.00168
0.007
DataSet_01_272
View details
AGAP1
236839408_236839567_236817381_236817550_236877105_236877267
0.00012
0.17
DataSet_01_272
View details
AHSG
186337570_186337729_186336324_186336426_186338374_186339107
0.00152
-0.02
DataSet_01_272
View details
ALB
74270837_74270890_74270003_74270123_74272345_74272478
0.00000
0.029
DataSet_01_272
View details
ALB
74270663_74270890_74270003_74270123_74272345_74272478
0.00101
0.009
DataSet_01_272
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APOC1
45417928_45417990_45417503_45417746_45418128_45418206
0.00000
0.1
DataSet_01_272
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APOC3
116701291_116701353_116700607_116700656_116701488_116701595
0.00332
0.012
DataSet_01_272
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APOC3
116701208_116701353_116700630_116700656_116701488_116701612
0.00346
0.008
DataSet_01_272
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ARHGEF40
21555159_21555264_21553847_21554025_21555478_21555622
0.00806
-0.2
DataSet_01_272
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ATAT1
30609564_30609647_30608153_30608199_30609952_30610024
0.00750
0.581
DataSet_01_272
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Showing 1 to 10 of 92 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACSL3
223791734_223791907_223793579_223793654_223789173_223789313
0.00818
0.052
DataSet_01_272
View details
ADD1
2877622_2877837_2883624_2883787_2845583_2845751
0.00357
-0.165
DataSet_01_272
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AFP
74303890_74304023_74316331_74316470_74302876_74302928
0.00017
-0.088
DataSet_01_272
View details
AHSG
186334975_186335164_186337645_186337729_186334231_186334316
0.00000
0.19
DataSet_01_272
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AHSG
186334975_186335139_186337645_186337729_186334231_186334316
0.00000
0.109
DataSet_01_272
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AHSG
186336079_186336280_186336324_186336426_186334975_186335139
0.00045
-0.01
DataSet_01_272
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AHSG
186334972_186335139_186336079_186336280_186334231_186334316
0.00046
0.282
DataSet_01_272
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AHSG
186336324_186336426_186337645_186337729_186334972_186335139
0.00247
0.069
DataSet_01_272
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AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00600
-0.006
DataSet_01_272
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AP2M1
183894738_183894855_183896644_183896910_183892642_183892747
0.00055
-0.135
DataSet_01_272
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Showing 1 to 10 of 94 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AL136419.6
24682614_24683357_24683199_24683357_24680885_24681035
0.00435
-0.095
DataSet_01_272
View details
BCL2L2-PABPN1
23793346_23793537_23793346_23793498_23794455_23794578
0.00022
0.123
DataSet_01_272
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EEF1B2
207024657_207024783_207024657_207024742_207025280_207025434
0.00038
0.021
DataSet_01_272
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EIF4G2
10823207_10823756_10823595_10823756_10822496_10822634
0.00205
0.084
DataSet_01_272
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FKBP10
39976605_39976851_39976605_39976713_39977198_39977341
0.00000
-0.067
DataSet_01_272
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GNB2L1
180669173_180669345_180669285_180669345_180668491_180668639
0.00130
0.011
DataSet_01_272
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HCCS
11139026_11139152_11139026_11139113_11139731_11141198
0.00621
0.209
DataSet_01_272
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NOP56
2636756_2636962_2636756_2636860_2637046_2637195
0.00459
0.033
DataSet_01_272
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PPCS
42922231_42922473_42922231_42922299_42922917_42923021
0.00234
-0.313
DataSet_01_272
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RP11-986E7.7
95078633_95078784_95078633_95078780_95080770_95081421
0.00495
0.052
DataSet_01_272
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Showing 1 to 10 of 12 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACTG1
79478928_79479168_79478928_79479141_79479257_79479386
0.00551
0.013
DataSet_01_272
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ARGLU1
107209906_107209999_107209906_107209964_107211779_107212005
0.00237
-0.285
DataSet_01_272
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ATP6V1G2-DDX39B
31508190_31508343_31508190_31508311_31509726_31509925
0.00190
0.165
DataSet_01_272
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C17orf76-AS1
16342894_16343567_16343498_16343567_16342640_16342728
0.00605
0.051
DataSet_01_272
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DDX39B
31508098_31508441_31508098_31508311_31509726_31510225
0.00045
0.088
DataSet_01_272
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DHRS2
24110874_24112428_24112360_24112428_24108967_24109104
0.00402
-0.035
DataSet_01_272
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FRG1B
29623128_29623254_29623167_29623254_29614260_29614327
0.00629
-0.205
DataSet_01_272
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FTCD
47558793_47558966_47558793_47558837_47565330_47565435
0.00201
-0.087
DataSet_01_272
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FTH1
61732458_61732584_61732458_61732577_61732840_61732915
0.00040
0.017
DataSet_01_272
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GPX4
1106240_1106462_1106398_1106462_1105656_1105808
0.00051
-0.187
DataSet_01_272
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Showing 1 to 10 of 22 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
CCS
66366586_66367107_66366586_66366724_66366929_66367107
0.00486
0.185
DataSet_01_272
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ERBB3
56487882_56488340_56487882_56487973_56488185_56488340
0.00080
-0.084
DataSet_01_272
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ETV4
41622641_41623036_41622641_41622735_41622925_41623036
0.00229
-0.139
DataSet_01_272
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FTH1
61732458_61732987_61732458_61732577_61732840_61732987
0.00042
0.032
DataSet_01_272
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GNB2L1
180668491_180669345_180668491_180668639_180669285_180669345
0.00005
0.02
DataSet_01_272
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MLXIPL
73010693_73011119_73010693_73010809_73010968_73011119
0.00030
-0.153
DataSet_01_272
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NOTUM
79916810_79917442_79916810_79916871_79917346_79917442
0.00027
-0.028
DataSet_01_272
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PI4KAP1
20397877_20398336_20397877_20397985_20398184_20398336
0.00612
-0.067
DataSet_01_272
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PNPLA2
823693_824130_823693_823855_823997_824130
0.00869
-0.024
DataSet_01_272
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UBC
125396193_125398320_125396193_125397780_125398008_125398320
0.00557
0.021
DataSet_01_272
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
23636275
G
T
0.00185
HNRNPR
-
FALSE
chr1
1419768
A
G
0.00189
ATAD3B
+
TRUE
AluYk2
SINE,Alu
chr1
179041705
A
T
0.00068
FAM20B
+
FALSE
chr1
28834586
G
A
0.00044
SNHG3,RCC1
+
FALSE
FRAM
SINE,Alu
chr1
39305002
A
T
0.00089
RRAGC
-
FALSE
chr1
10041422
A
G
0.00115
NMNAT1
+
TRUE
AluYj4
SINE,Alu
chr1
46159809
T
A
0.00605
TMEM69
+
FALSE
chr1
150548877
C
G
0.00071
MCL1
-
FALSE
chr1
11347152
A
T
0.00401
UBIAD1
+
FALSE
chr1
104097685
C
T
0.00028
RNPC3,AMY2B
+
FALSE
Showing 1 to 10 of 446 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression