Dataset Overview
RBPSBDS
Knock-MethodshRNA
RBP FamilySBDS_C
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR219DXZ
PlatformHiSeq
Pubmed ID32252787

SBDS - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of SBDS
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of SBDS


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr3195451488CT1.73907E-06MUC20+FALSE
chr2128605225GA0.00401POLR2D-FALSE
chr1157092835GA0.00595.FALSE
chrX118672561TC2.49155E-08CXorf56-TRUEAluSxSINE,Alu
chr1150548887CT0.00014MCL1-FALSE
chr3197024681TC0.00018DLG1-FALSE
chr237431604AG0.00876CEBPZOS,CEBPZ+,-FALSEAluScSINE,Alu
chr1112266787GT0.00873FAM212B-FALSE
chr178029905TA0.00256ZZZ3-FALSE
chr176252687TC0.00021RABGGTB+FALSE
chr129395329GA0.00814LINC00987+FALSE
chr1327407AG3.55459E-07.FALSE
chr3156259348GA0.00899SSR3-FALSEAluSq2SINE,Alu
chr146076468AG0.00069NASP+TRUEAluSxSINE,Alu
chr7100958270TC0.00087LOC101927746,IFT22+,-FALSE
chr1252710715GA0.00729KRT83-FALSE
chr1148577409CA0.00897NBPF15+FALSE
chr4142945451TC0.00585.FALSE
chr287755101CT0.00431LINC00152+FALSE
chr1690037828GA0.00029CENPBD1-FALSETigger12SINE,Alu
chr579923990TC0.00812DHFR-TRUEAluSpSINE,Alu
chr1145513112AG0.00080NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr1788795TG0.00333LINC01128+FALSECharlie19aSINE,Alu
chr144088117GT0.00731PTPRF+FALSE(T)nSINE,Alu
chr111734730CT7.77156E-16MAD2L2-FALSE
chr1145283718GA0.00897NBPF20,NOTCH2NL+FALSE
chr144423703CT1.17684E-14IPO13+FALSE
chr1100489571GA1.40531E-05SLC35A3+FALSEAluScSINE,Alu
chr537288767TC0.00928.FALSEFLAM_CSINE,Alu
chr128662253AG0.00117MED18+TRUEAluSq2SINE,Alu
chr4109542624GA0.00048RPL34+FALSEMIRbSINE,Alu
chr9114696428GT0.00163UGCG+FALSE(TGTTTTT)nSINE,Alu
chr1236702210AG0.00153LGALS8+FALSE
chr7143003517TA0.00251CASP2+FALSEAluYSINE,Alu
chr5290324TA0.00729PDCD6+FALSE
chr8143763622CT0.00470PSCA+FALSE
chr674133914TC0.00014.FALSEAluYSINE,Alu
chr3196670095CA1.97381E-07NCBP2-AS2+FALSE
chr2018468512TC0.00072RBBP9-TRUEAluSz6SINE,Alu
chr1115592820TC0.00107TSPAN2-FALSE
chr136068243TC0.00217PSMB2-TRUEAluScSINE,Alu
chr116812082AG0.00545CROCCP3-FALSE
chr2172179003TC0.00192METTL8-TRUEAluYSINE,Alu
chr775677504CT0.00768MDH2+FALSE
chr1016554732TA0.00706PTER+FALSE
chr237331107TC0.00020.FALSEAluSx1SINE,Alu
chr1541591021AG0.00427OIP5-AS1+TRUEAluSx1SINE,Alu
chr1541597437TA0.00217.FALSEAluSz6SINE,Alu
chr5126171974CT0.00867LMNB1+FALSE
chr1179829401TC0.00118TOR1AIP2-TRUEAluJrSINE,Alu
chr1113511408AG0.00738.FALSEAluYSINE,Alu
chr11309464CT3.88389E-12AURKAIP1-FALSE
chr3196670099AC6.06146E-06NCBP2-AS2+FALSE
chr171683647TC0.00763SMYD4-TRUEAluJbSINE,Alu
chr1352327020GA0.00019WDFY2+FALSE
chr613790964TC5.10728E-05MCUR1-TRUEAluSx1SINE,Alu
chr2136541072TC0.00496UBXN4+FALSE
chr596350710GA0.00302LNPEP+FALSE
chr5140240514AG0.00151PCDHA1,PCDHA2,PCDHA3,PCDHA4,PCDHA5,PCDHA6,PCDHA7,PCDHA8,PCDHA9,PCDHA10+FALSEAluYSINE,Alu
chr159246520AC7.56706E-05JUN-FALSE
chr125570566CG0.00326RSRP1-FALSEAluSINE,Alu
chr1272096318AG0.00547TMEM19+TRUEAluSz6SINE,Alu
chr579923292CG0.00305DHFR-FALSEAluJrSINE,Alu
chr1116609833GA0.00773SLC22A15+FALSE
chr16603884CG0.00118CAPN15+FALSE
chr1789187CG5.07459E-05LINC01128+FALSE
chr1942375564AG0.00117.FALSEAluSxSINE,Alu
chr946687845GC0.00389FGF7P6,LOC554249,LOC102724238+,-FALSE
chr174928416AG0.00941KIF1C+TRUEAluSzSINE,Alu
chr2223807817AC0.00991ACSL3+FALSE(A)nSINE,Alu
chr228635740TC0.00358FOSL2+FALSE
chr1591044383GT0.00440IQGAP1+FALSE
chr5110463621GT0.00786WDR36+FALSE(T)nSINE,Alu
chr2206987738TC0.00859.FALSEAluJbSINE,Alu
chr115736656AG0.00958EFHD2+FALSE
chr119542250TC9.94571E-09LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr342266360TC0.00279TRAK1+FALSE
chr1718111804TG0.00487ALKBH5+FALSE(TTTTGTT)nSINE,Alu
chr340503561AT0.00012RPL14+FALSE
chr1120162587GA0.00730ZNF697-FALSE
chr273460316GT0.00368PRADC1-FALSE(CGGCGC)nSINE,Alu
chr9136209399AT0.00011MED22-FALSE
chr1150937961AC0.00060CERS2-FALSEG-richSINE,Alu
chr285773623TC0.00203GGCX-TRUEAluSx1SINE,Alu
chr136386884CT0.00024AGO1+FALSE
chr1245008386GC0.00041.FALSEMER2SINE,Alu
chr5149364144AG0.00014SLC26A2+TRUEAluSc8SINE,Alu
chr126608019TA3.63623E-05.FALSE
chr237331116TC0.00481.FALSEAluSx1SINE,Alu
chr457801150AT0.00462REST+FALSE
chr372426059TA0.00417RYBP-FALSE
chr16161107AT0.00218KCNAB2+FALSE
chr275118856TC1.43220E-05HK2+FALSE(ATTTTA)nSINE,Alu
chr7100031496TA0.00119MEPCE+FALSE
chr1741144251TG0.00014RUNDC1+FALSE
chr237331275TC0.00884.FALSEAluSx1SINE,Alu
chr1565442506TC0.00088CLPX-TRUEAluSg4SINE,Alu
chr1163394020AT0.00175ATL3-FALSE
chr9115447528TC0.00112INIP-TRUEAluJbSINE,Alu
chr2131131424GC0.00845PTPN18+FALSE
chr115015GC0.00809WASH7P-FALSE
chr3101369192CT0.00761ZBTB11-FALSE
chr299812817AG0.00018MRPL30+TRUEAluJbSINE,Alu
chr177556766TA0.00576PIGK-FALSE
chr1121133998TA0.00171SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr1117645998AG0.00057.FALSE
chr16582701TC1.54245E-05NOL9-TRUEAluSgSINE,Alu
chr1200521412GA0.00292KIF14-FALSE
chr19416568CT0.00061SPSB1+FALSE
chr175288079AC0.00085RABEP1+FALSE
chr3172117459CA0.00791FNDC3B+FALSE
chr2217366191TA0.00306.FALSE
chr19328120AG1.75282E-05H6PD+TRUEAluJrSINE,Alu
chr286364710TC0.00056PTCD3+FALSE
chr5130537154AG0.00951LYRM7+TRUEAluSpSINE,Alu
chr1113239382GA0.00519MOV10+FALSE
chr41193026AG0.00471SPON2,LOC100130872-FALSEAluSpSINE,Alu
chr110521237TC0.00348DFFA-TRUEAluYSINE,Alu
chr7128144035AG0.00054.FALSEAluSq2SINE,Alu
chr129464178GA0.00081LOC642846+FALSE
chr765992665TC2.17687E-05.FALSEAluJrSINE,Alu
chr1253807911AT0.00355SP1+FALSE
chr3195964298AG0.00263.FALSE
chr1145375869GA0.00480NBPF20,NBPF10+FALSE
chr211323276TC0.00219ROCK2-FALSE
chr7117825681AG1.90524E-05LSM8+FALSE
chr8145159705GA0.00383MAF1+FALSE
chr136614708CT0.00201TRAPPC3-FALSE
chr1154323557CT0.00018ATP8B2+FALSE
chr552388459AT0.00052ITGA2+FALSE
chr1773819348TC0.00213UNK+FALSE
chr570503890AT0.00188.FALSE
chr110519912TC5.10285E-06.FALSEAluJrSINE,Alu
chr1880052CT0.00231NOC2L-FALSE
chr16314743CT6.72719E-05GPR153-FALSE
chr171946503CG0.00154DPH1,OVCA2+FALSE
chr1118066459AG0.00788MAN1A2+FALSE
chr119543783TC0.00822LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr194930345GA0.00223ABCD3+FALSE
chr7137561077CA0.00995CREB3L2-FALSE
chr1144917546AG0.00614NBPF20,PDE4DIP+,-FALSE
chr1767539228GC0.00200.FALSE
chr236776053TC0.00029CRIM1+FALSE
chr119542679TC1.36514E-06LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr187200770CT0.00623SH3GLB1+FALSE
chr136534086AG0.00157.FALSEFLAM_ASINE,Alu
chr192946618AG0.00062GFI1-FALSE
chr1593198678TC0.00064FAM174B-FALSE(GCCGCT)nSINE,Alu
chr1109475629AG0.00305GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chr124134721TC0.00113HMGCL-FALSE
chr1150190851GT0.00339ANP32E-FALSE
chr110520764TC0.00542DFFA-TRUEAluSc8SINE,Alu
chr1153533813AT0.00451S100A2-FALSE
chr2118583874CG0.00569DDX18+FALSE
chr126449882AG0.00783PDIK1L+FALSE
chr131342374AC0.00446SDC3-FALSE(A)nSINE,Alu
chr1145500919CT0.00029NBPF20,NBPF10,LIX1L+FALSE
chr237327677TC0.00019.FALSE
chr349396751TC0.00000RHOA-FALSE
chr1118552273CT0.00243.FALSE
chr315112501TC2.98131E-05RBSN-TRUEAluSq2SINE,Alu
chr111783295GA0.00977.FALSEMER58BSINE,Alu
chr632789807CT0.00281.FALSE
chr119238556GA6.03260E-07IFFO2-FALSE
chr1150548883AC0.00255MCL1-FALSE
chr352084404AT0.00032DUSP7-FALSE(A)nSINE,Alu
chr1119427687GC0.00823TBX15-FALSE
chr237331077TC0.00937.FALSEAluSx1SINE,Alu
chr11650797AG3.70820E-05CDK11B,CDK11A-FALSE
chr132799437CT0.00318MARCKSL1-FALSE
chr168940887TG0.00293DEPDC1-FALSEMIRSINE,Alu
chr1111969752AG0.00531OVGP1-FALSE
chr1563363388GT0.00096TPM1+FALSE
chr5134670071AT0.00405C5orf66,H2AFY+,-FALSE
chrX9863112AG0.00498SHROOM2+FALSE
chr16283260TC0.00402ICMT-TRUEAluSx3SINE,Alu
chr136067760TC0.00258PSMB2-TRUEAluSzSINE,Alu
chr167874696TC0.00014SERBP1-TRUEAluSx3SINE,Alu
chr2179973026TC0.00210SESTD1-FALSE
chr315114421TC0.00353RBSN-TRUEAluYSINE,Alu
chr2201842492TC0.00107FAM126B-TRUEAluJbSINE,Alu
chr237328034TC0.00047.FALSE
chr1211921702TC0.00014LPGAT1-FALSE
chr178483452CT0.00094DNAJB4+FALSEL1MB7SINE,Alu
chr799917927TC0.00320SPDYE3+FALSEAluJbSINE,Alu
chr1246829616TC0.00029CNST+FALSE
chr1146467146AG0.00510NBPF20,NBPF25P,NBPF12+TRUEL1MC4SINE,Alu
chr1089004545TC0.00192NUTM2A-AS1-FALSEMSTASINE,Alu
chr1156044222GT0.00758MEX3A-FALSE(T)nSINE,Alu
chr1206516261CT0.00179SRGAP2+FALSE
chr1120163831AG0.00706ZNF697-FALSE
chr123519504TA3.21384E-05HTR1D-FALSE
chr21636938CT0.00072PXDN-FALSE(T)nSINE,Alu
chr1200827638AG0.00665CAMSAP2+FALSE
chr133149373AG0.00264SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr324019977AC0.00281NR1D2+FALSE
chr2242173247GA0.00345HDLBP-FALSE
chr145474230GA0.00012HECTD3-FALSE
chr1117530477GA0.00223PTGFRN+FALSE
chr476568479TA0.00825G3BP2-FALSE
chr5130536847AG0.00917LYRM7+TRUEAluSx4SINE,Alu
chr1220231963TC0.00343RNU5F-1,BPNT1+,-FALSEAluSzSINE,Alu
chr540832550CT7.98859E-06RPL37-FALSE
chr138326704TC0.00328INPP5B-TRUEAluJrSINE,Alu
chr110221287AG0.00961UBE4B+FALSE
chr167874697TC0.00022SERBP1-TRUEAluSx3SINE,Alu
chr186049392CA0.00322CYR61+FALSE
chr269688754TC0.00319AAK1-TRUEAluSq2SINE,Alu
chr2128620436CT0.00342AMMECR1L-FALSE
chr2173461888AG0.00110PDK1+TRUEAluJrSINE,Alu
chr1110551680CT0.00415AHCYL1+FALSE
chr11337841CA0.00186MRPL20-FALSE
chr1144606963GT0.00080NBPF20+FALSE
chr116891365GA0.00475NBPF1-FALSE
chr116577794CT0.00805FBXO42-FALSE
chr345721891AG0.00417LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr131732603AC0.00164SNRNP40-FALSE
chr1246714587GA0.00150TFB2M-FALSE
chr39848198GT0.00295ARPC4,ARPC4-TTLL3+FALSE(T)nSINE,Alu
chr5179382563TC0.00704RNF130-FALSE
chr115755248CT0.00405EFHD2+FALSE
chr16283306TC2.62084E-05ICMT-TRUEAluSx3SINE,Alu
chr6158613395CA0.00031GTF2H5+FALSE
chr177123232CG0.00250DLG4,ACADVL+,-FALSE
chr46689813CA0.00141.FALSEL2bSINE,Alu
chrX24095325AG7.48023E-10EIF2S3+TRUEAluSxSINE,Alu
chr4663908AG0.00320PDE6B+FALSE
chr128662186AG0.00774MED18+TRUEAluSq2SINE,Alu
chr167874696TC0.00420SERBP1-TRUEAluSx3SINE,Alu
chr1145512925AG0.00238NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr113942885CA0.00038PDPN+FALSE
chr2206988075GA0.00672NDUFS1-FALSE
chr1205687213TA0.00950NUCKS1-FALSE
chr1230975454AG0.00438C1orf198-FALSE

Differential Expression Gene Analysis