Dataset Overview
RBP
FTO
Knock-Method
shRNA
RBP Family
FTO_NTD
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR389HFU
Platform
HiSeq
Pubmed ID
32252787
FTO - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of FTO
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1CF
34.93
29.64
0.87951
1.80091E-05
0.00014
A2M
2480.13
3991.85
0.57589
0.00131
0.00528
AAAS
18.44
11.82
-0.38902
0.03690
0.08154
AADAC
0.25
2.66
4.02016
1.27456E-23
1.94399E-21
AADAT
10.61
6.74
-0.52594
0.01461
0.03866
AAED1
3.77
3.81
0.49200
0.02362
0.05694
AAGAB
9.8
9.64
0.48461
0.02719
0.06399
AAK1
6.63
8.05
0.83911
9.57661E-06
7.91533E-05
AARS2
5.75
2.76
-0.75596
0.00013
0.00074
AASDH
4.35
3.78
0.42486
0.03621
0.08034
Showing 1 to 10 of 6,300 entries
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Function Analysis of Target Genes of FTO
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC2
101556531_101556610_101554169_101554225_101556853_101557853
0.00124
0.315
DataSet_01_276
View details
AC003002.6
57902089_57902213_57901251_57901482_57905555_57905591
0.00124
-0.306
DataSet_01_276
View details
AC093838.4
132277386_132277515_132277107_132277239_132277669_132277994
0.00221
0.277
DataSet_01_276
View details
ACAA1
38173086_38173129_38170780_38170879_38173416_38173496
0.00732
-0.069
DataSet_01_276
View details
ACBD4
43216387_43216527_43215279_43215355_43220809_43221539
0.00565
-0.431
DataSet_01_276
View details
ACIN1
23540333_23540395_23538684_23538826_23540635_23540747
0.00578
0.206
DataSet_01_276
View details
ACSL3
223791734_223791960_223789173_223789313_223793579_223793654
0.00025
-0.071
DataSet_01_276
View details
ACSL3
223791734_223791907_223789173_223789313_223793579_223793654
0.00424
-0.017
DataSet_01_276
View details
ACTR1A
104250305_104250370_104248819_104248895_104262356_104262468
0.00783
0.031
DataSet_01_276
View details
ADAM22
87815929_87816016_87811272_87811339_87822430_87822554
0.00821
0.552
DataSet_01_276
View details
Showing 1 to 10 of 454 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9231839_9231927_9232234_9232411_9230296_9230453
0.00001
-0.069
DataSet_01_276
View details
ABAT
8829555_8829666_8839857_8839955_8768421_8768568
0.00000
-0.232
DataSet_01_276
View details
ABCF1
30548182_30548296_30550170_30550284_30547707_30547782
0.00000
0.21
DataSet_01_276
View details
ABHD14A
52012274_52012390_52014408_52014644_52011886_52012098
0.00000
0.36
DataSet_01_276
View details
ABLIM1
116207638_116207785_116211382_116211430_116205070_116205162
0.00181
0.117
DataSet_01_276
View details
AC003002.6
57902089_57902213_57904168_57904316_57901251_57901482
0.00258
-0.375
DataSet_01_276
View details
ACADVL
7126451_7126556_7126962_7127049_7125985_7126184
0.00000
-0.185
DataSet_01_276
View details
ACSL3
223791734_223791907_223793579_223793654_223789173_223789313
0.00077
-0.053
DataSet_01_276
View details
ACSS3
81528594_81528783_81532909_81533044_81503338_81503483
0.00068
-0.146
DataSet_01_276
View details
ADAM9
38940159_38940240_38940486_38940592_38934746_38934930
0.00486
0.143
DataSet_01_276
View details
Showing 1 to 10 of 394 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC6P1
18584198_18584419_18584198_18584382_18585641_18585757
0.00375
-0.181
DataSet_01_276
View details
ARFIP2
6499270_6499428_6499285_6499428_6498947_6499122
0.00014
-0.082
DataSet_01_276
View details
ARIH2
48962150_48962404_48962150_48962272_48964894_48965246
0.00256
-0.087
DataSet_01_276
View details
ATP5J2-PTCD1
99063733_99063787_99063751_99063787_99057708_99057816
0.00975
-0.086
DataSet_01_276
View details
BCL2L2-PABPN1
23793346_23793537_23793346_23793498_23794455_23794578
0.00113
-0.097
DataSet_01_276
View details
CALD1
134617738_134618828_134617738_134618141_134625842_134625988
0.00125
0.178
DataSet_01_276
View details
CCHCR1
31112405_31112565_31112463_31112565_31111038_31111190
0.00165
0.098
DataSet_01_276
View details
CFB
31915732_31915971_31915732_31915858_31916150_31916289
0.00460
0.028
DataSet_01_276
View details
CSNK1G2
1979493_1979642_1979493_1979617_1979750_1979834
0.00524
-0.089
DataSet_01_276
View details
CTNND1
57529268_57529591_57529268_57529518_57556508_57556627
0.00132
0.157
DataSet_01_276
View details
Showing 1 to 10 of 63 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABLIM1
116207638_116207785_116207638_116207779_116211382_116211430
0.00913
0.132
DataSet_01_276
View details
ACLY
40070037_40070167_40070037_40070149_40075132_40075240
0.00009
0.167
DataSet_01_276
View details
ACTG1
79478928_79479168_79478928_79479141_79479257_79479386
0.00029
-0.024
DataSet_01_276
View details
AP1G2
24031170_24031316_24031170_24031262_24031496_24031624
0.00589
-0.088
DataSet_01_276
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APOC4
45451957_45452117_45452019_45452117_45451722_45451790
0.00250
-0.022
DataSet_01_276
View details
ARL2BP
57282326_57282555_57282448_57282555_57279978_57280053
0.00787
0.184
DataSet_01_276
View details
ATG9A
220074951_220075020_220074951_220074992_220075102_220075197
0.00946
-0.043
DataSet_01_276
View details
ATP6V1G2-DDX39B
31508190_31508343_31508190_31508311_31509726_31509925
0.00731
-0.12
DataSet_01_276
View details
ATXN2L
28842282_28842393_28842305_28842393_28841935_28842111
0.00360
-0.086
DataSet_01_276
View details
AUP1
74754862_74754983_74754862_74754965_74755066_74755133
0.00537
-0.015
DataSet_01_276
View details
Showing 1 to 10 of 91 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAD8
134129501_134131073_134129501_134129639_134130937_134131073
0.00312
0.403
DataSet_01_276
View details
ACADVL
7125985_7126556_7125985_7126184_7126451_7126556
0.00001
0.183
DataSet_01_276
View details
ACTB
5568791_5569294_5568791_5569031_5569165_5569294
0.00002
0.019
DataSet_01_276
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ACTB
5567634_5568350_5567634_5567816_5567911_5568350
0.00131
0.008
DataSet_01_276
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ACTG1
79477952_79478652_79477952_79478134_79478213_79478652
0.00000
0.018
DataSet_01_276
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ADRBK1
67049741_67050013_67049741_67049836_67049905_67050013
0.00344
-0.06
DataSet_01_276
View details
AKR1B1
134132049_134132813_134132049_134132133_134132731_134132813
0.00997
0.067
DataSet_01_276
View details
ANXA4
70035037_70037805_70035037_70035128_70037725_70037805
0.00248
0.036
DataSet_01_276
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AP1G2
24031170_24031624_24031170_24031262_24031496_24031624
0.00177
-0.096
DataSet_01_276
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APEX1
20923384_20923862_20923384_20923548_20923736_20923862
0.00094
0.013
DataSet_01_276
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
212515613
C
T
0.00286
PPP2R5A
+
FALSE
chr1
149581854
C
A
0.00175
LINC00623,LINC00869,LOC103091866
+
FALSE
L2b
SINE,Alu
chr1
23636277
A
T
0.00295
HNRNPR
-
FALSE
chr1
169799880
G
T
0.00118
C1orf112
+
FALSE
chr1
143399333
T
A
0.00339
.
FALSE
L1MC4
SINE,Alu
chr1
145273302
A
G
0.00504
NBPF20,NOTCH2NL
+
FALSE
chr1
19543247
T
C
5.23836E-05
LOC101927895,EMC1
+,-
FALSE
AluJb
SINE,Alu
chr1
145512166
T
A
0.00823
NBPF20,NBPF10,RBM8A,GNRHR2
+,-
FALSE
AluY
SINE,Alu
chr1
93297590
C
A
0.00325
.
FALSE
chr1
113672640
A
G
0.00629
.
FALSE
AluJb
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression