Dataset Overview
RBPFTO
Knock-MethodshRNA
RBP FamilyFTO_NTD
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR389HFU
PlatformHiSeq
Pubmed ID32252787

FTO - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of FTO
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of FTO


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr2109401286GT0.00087RANBP2+FALSE
chr1212515613CT0.00286PPP2R5A+FALSE
chr7286402AG1.78989E-09FAM20C+FALSE
chr333186111TC0.00349CRTAP+FALSELTR16A1SINE,Alu
chr5130538304AG0.00050LYRM7+TRUEFAMSINE,Alu
chr237327662TC0.00220.FALSE
chr1149581854CA0.00175LINC00623,LINC00869,LOC103091866+FALSEL2bSINE,Alu
chr1591044383GT0.00440IQGAP1+FALSE
chr123636277AT0.00295HNRNPR-FALSE
chr5151041873AG0.00136SPARC-FALSE
chr1169799880GT0.00118C1orf112+FALSE
chr1143399333TA0.00339.FALSEL1MC4SINE,Alu
chr1145273302AG0.00504NBPF20,NOTCH2NL+FALSE
chr1256510709GA0.00047RPL41+FALSE
chr344791406TC0.00598KIAA1143-TRUEAluJrSINE,Alu
chr119543247TC5.23836E-05LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr1145512166TA0.00823NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr2025428750AG3.17139E-06GINS1+TRUEAluJbSINE,Alu
chr6160113872AG0.00863SOD2-FALSE
chr193297590CA0.00325.FALSE
chr2191556844TC0.00024NAB1+FALSE
chr13111301048TC0.00037CARS2-FALSE
chr1113672640AG0.00629.FALSEAluJbSINE,Alu
chr1492585231TC0.00023NDUFB1-TRUEAluSgSINE,Alu
chr12125511961AG1.08093E-06THRIL-FALSEAluSx1SINE,Alu
chr1144607387GC0.00016NBPF20+FALSE
chr122445725CG0.00913WNT4-FALSE
chr1153920564AG0.00323CRTC2-FALSE
chr5133738270TC0.00067CDKN2AIPNL-TRUEFRAMSINE,Alu
chr642045563AG4.21139E-05TAF8+TRUEAluSzSINE,Alu
chr1144828795CG0.00887NBPF20,NBPF9+FALSE
chr1179326315AG0.00187SOAT1+TRUE
chr197084578AG0.00346ZNF557+TRUEAluJbSINE,Alu
chr237328042TC6.80414E-06.FALSE
chr4114135223AT5.22810E-05ANK2+FALSE
chr119934930TC0.00026MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr119633555GA0.00219AKR7A2-FALSE
chr128836975AG0.00023SNHG3,RCC1+TRUEAluScSINE,Alu
chr136068276TC0.00110PSMB2-TRUEAluScSINE,Alu
chr138279987TC0.00980MTF1-FALSE
chr132697109AG0.00015EIF3I+FALSEAluSpSINE,Alu
chr744618353TC0.00168TMED4-TRUEAluSq2SINE,Alu
chr19643107AG0.00859.FALSEAluSxSINE,Alu
chr2170403030TC0.00294FASTKD1-FALSE
chr23607238CT0.00222RNASEH1-AS1+FALSE
chr1151092875AG0.00154GABPB2+TRUEAluSpSINE,Alu
chr2227662565AC0.00028IRS1-FALSE
chr236704035CA0.00012CRIM1+FALSE
chr12133298053AG7.95391E-05PGAM5+TRUEAluJoSINE,Alu
chr1746024807CT0.00295PNPO+FALSE
chr1180247474TC0.00022.FALSE
chr1145513125AG0.00274NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr162628606AG0.00164PATJ+TRUEAluSg4SINE,Alu
chr153679610GA0.00217CPT2+FALSEAluSzSINE,Alu
chr3195243024CA0.00729PPP1R2-FALSE
chr3194361768CT1.49766E-06LSG1-FALSEMSTASINE,Alu
chr136602202TC0.00122TRAPPC3-FALSE
chr131732602CA0.00148SNRNP40-FALSE
chrX77083673TC0.00090MAGT1-TRUEAluSz6SINE,Alu
chr128826128AG0.00483PHACTR4+TRUEAluJbSINE,Alu
chr1183094547TC0.00277LAMC1+FALSE
chr146830257CT0.00208NSUN4+FALSEAluSx1SINE,Alu
chr132372387AC0.00757PTP4A2-FALSE(CA)nSINE,Alu
chr310192720AG0.00110VHL+TRUEAluSx1SINE,Alu
chr227001973CT0.00327SLC35F6+FALSEAluSxSINE,Alu
chr315114759GA1.99109E-05RBSN-FALSE
chr121810586CT0.00540NBPF3+FALSE
chr152520864AT0.00041TXNDC12-FALSE
chr1144917841TC4.47769E-05NBPF20,PDE4DIP+,-FALSE
chr9100777799GA0.00675ANP32B+FALSE
chr1179326847AG0.00021SOAT1+TRUEAluJoSINE,Alu
chr119542631TC0.00198LOC101927895,EMC1+,-FALSEFRAMSINE,Alu
chr1450361171CT0.00017ARF6+FALSE(T)nSINE,Alu
chr140307166GA0.00026TRIT1-FALSE
chr348485493AG7.09932E-12TMA7+FALSE
chr5134302899AG0.00025.FALSEAluSq2SINE,Alu
chr237327665TC2.45403E-06.FALSE
chr110520258TC0.00152.FALSEAluSxSINE,Alu
chrX3523061CG0.00023PRKX-FALSE(AC)nSINE,Alu
chr671298815TA0.00287.FALSE
chr1148252049AC0.00042NBPF8,NBPF14,NBPF9-FALSE
chr186986259GA5.32960E-05LAMA1-FALSE
chr1113243096GT0.00114MOV10+FALSE
chr537290323TC0.00029.FALSEAluSzSINE,Alu
chr1419686329GA0.00117DUXAP10+FALSE
chr19324451CT0.00266H6PD+FALSE
chr1935741552CT0.00165LSR+FALSE
chr41380585AG0.00644UVSSA+TRUEAluJrSINE,Alu
chr1144053663AT0.00155.FALSE
chr110520174TC0.00163.FALSEAluSxSINE,Alu
chr298264656TA0.00993COX5B+FALSE
chr1320246634TG0.00071MPHOSPH8+FALSE
chr16582701TC1.54245E-05NOL9-TRUEAluSgSINE,Alu
chr11490771CT0.00600PTDSS2+FALSE
chr1138356CA0.00481LOC729737-FALSE
chr4177252327AG2.51883E-09SPCS3+TRUE
chr1159887904AT8.82173E-05TAGLN2-FALSE
chr274332837GT4.72839E-05TET3+FALSE
chr3100428460GC5.60949E-08TFG+FALSE
chr634254585GT0.00519.FALSEAluSq2SINE,Alu
chr110518688TC0.00341.FALSEAluSx1SINE,Alu
chr791630345GA0.00473AKAP9+FALSE
chr110517314TC0.00073.FALSEAluJrSINE,Alu
chr145976723TC0.00733MMACHC,PRDX1+,-FALSE
chr119428086GT0.00449UBR4-FALSE
chr187213182AT0.00072SH3GLB1+FALSE
chr1201438098TG2.75480E-05PHLDA3-FALSE
chr12100562935GT0.00074GOLGA2P5-FALSEAluSgSINE,Alu
chr1629454768AG0.00564SMG1P6,BOLA2-SMG1P6-FALSE
chr1757279281AG0.00055PRR11+TRUEAluSq2SINE,Alu
chr127202982TC0.00850.FALSEAluSq2SINE,Alu
chr1681064494AG8.13539E-06CENPN+TRUEAluSgSINE,Alu
chr12125511404AG0.00201THRIL-FALSEAluSx1SINE,Alu
chr1543767774GC0.00057TP53BP1-FALSE
chr116890130AC0.00412NBPF1-FALSE
chr1168218573AG0.00202.FALSEAluSzSINE,Alu
chr4109733172TC0.00480COL25A1-FALSE
chr830536146TC1.15312E-06GSR-TRUEAluJrSINE,Alu
chr177166017GA0.00627.FALSE
chr119670869AG0.00568CAPZB-FALSE
chr119238556GA6.03260E-07IFFO2-FALSE
chr1117531621AG0.00577PTGFRN+FALSE
chr286249961TC0.00067LOC90784-TRUEAluJrSINE,Alu
chr1151742798TC0.00626OAZ3+FALSE
chr1150446056GA0.00945RPRD2+FALSE(A)nSINE,Alu
chr1214529742TC6.22071E-05PTPN14-TRUE
chr38922054TC0.00464RAD18-FALSE
chr11421186CT0.00834ATAD3B+FALSE
chr175196073CT0.00159CRYZ-FALSE
chr1118167515CT3.85037E-05FAM46C+FALSE
chr1939982631AG0.00316TIMM50+TRUEAluJrSINE,Alu
chr5114547295CA0.00294PGGT1B-FALSE
chr12133298349AG0.00000PGAM5+TRUEAluSpSINE,Alu
chr110042987AG0.00149NMNAT1+TRUEAluScSINE,Alu
chr349453834CT0.00518TCTA+FALSE
chr110518052TC7.90759E-05.FALSEAluJrSINE,Alu
chr1230415244TC0.00780GALNT2+FALSE
chr314986098TC3.23580E-05FGD5-AS1-TRUEFLAM_CSINE,Alu
chr192975262CA0.00238EVI5-FALSE
chr210074384GA0.00765TAF1B+FALSE
chr565120054CT0.00625NLN+FALSE
chr320025677GT0.00116RAB5A,PP2D1+,-FALSE
chr166058513AG0.00091LEPR+FALSE
chr1145688944AG0.00359NBPF20,NBPF10,RNF115+TRUEAluSc8SINE,Alu
chr7152551581TA0.00313ACTR3B+FALSE
chr154493259TC0.00203TMEM59-TRUEAluSz6SINE,Alu
chr1206557430CT0.00011SRGAP2+FALSE
chr229135468CG0.00262WDR43+FALSE
chr2128604232AT0.00652POLR2D-FALSE
chr34403394AG0.00388SUMF1-FALSE
chr514769103GA0.00104ANKH-FALSE
chr262095534TC0.00021CCT4-FALSE
chr1269237021AG0.00229MDM2+TRUE
chr937503313AG0.00584POLR1E+TRUEAluJbSINE,Alu
chr5122359494GC0.00043PPIC-FALSE
chr5205565GA0.00593CCDC127-FALSE
chr133961147TG0.00196ZSCAN20+FALSE
chr342266349CT0.00942TRAK1+FALSE
chr2242512138AG9.62871E-05BOK+FALSE
chr119665566AC0.00028CAPZB-FALSE
chr1223945582GT0.00304CAPN2+FALSEAluSxSINE,Alu
chr1937236432TC0.00333ZNF850-TRUEAluSpSINE,Alu
chr72274221TC0.00579MRM2-TRUEAluJrSINE,Alu
chr7102004748TC0.00050LOC100289561,LOC100630923+FALSE
chr1582336939GA2.47536E-05MEX3B-FALSE
chr11255400TC0.00224CPSF3L-FALSE
chr7102016321CT0.00201LOC100289561,LOC100630923+FALSE
chr4165998226TC0.00754TMEM192-TRUEAluSxSINE,Alu
chr7100957851TC0.00028LOC101927746,IFT22+,-FALSEMADE1SINE,Alu
chr1154128837GT0.00032TPM3-FALSE
chr1185069687CT0.00072RNF2+FALSE
chr347554503TG0.00720ELP6-FALSEAluSxSINE,Alu
chr233623905GT0.00262LTBP1+FALSE
chr5125961611AG0.00113PHAX+TRUEAluSz6SINE,Alu
chr2217366499AG0.00063.FALSEAluSzSINE,Alu
chr3184766301TC0.00025VPS8+FALSE
chr1541590288GT0.00349OIP5-AS1+FALSE
chr15102512797AG0.00080WASH3P+FALSE
chr210580506AT0.00294ODC1-FALSE
chr10129910475TG0.00061MKI67-FALSE
chr1118170485TC0.00281FAM46C+FALSE(TG)nSINE,Alu
chr16583701TC0.00029NOL9-FALSE
chr830536152TC0.00015GSR-TRUEAluJrSINE,Alu
chr128825418AG0.00525PHACTR4+TRUEAluSgSINE,Alu
chr159123655CT0.00655MYSM1-FALSE
chr136068295TC0.00057PSMB2-TRUEAluScSINE,Alu
chr110519912TC5.10285E-06.FALSEAluJrSINE,Alu
chr119543457TC0.00059LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr5154194420GA0.00137LARP1+FALSE
chr342592902TC0.00934SEC22C-FALSEAluJrSINE,Alu
chr344791062TC0.00035KIAA1143-FALSE
chr117326540GA0.00120ATP13A2-FALSE
chr1144595886GA0.00242NBPF20+FALSEAluJbSINE,Alu
chr1197093361GA8.55632E-06ASPM-FALSE
chr631236900GA0.00167.FALSE
chr1919791273AG0.00121ZNF101+TRUEAluSq2SINE,Alu
chr153378536TC0.00075ECHDC2-TRUEAluSpSINE,Alu
chr132638775AT0.00949KPNA6+FALSE(A)nSINE,Alu
chr2233446265TC0.00177EIF4E2+FALSE
chr154571491AG0.00538TCEANC2+TRUEAluScSINE,Alu
chr1774560725TC0.00476SNHG16+FALSETHE1BSINE,Alu
chr1148595665AG0.00062NBPF15+TRUEL1MC4SINE,Alu
chr128261658TG0.00280SMPDL3B+FALSE
chr128564252AG0.00118ATPIF1+FALSE
chr11447756GC0.00343ATAD3A+FALSE
chr1201438097GC2.75480E-05PHLDA3-FALSE
chr1120163248GA4.97770E-06ZNF697-FALSE
chr165298626TA0.00580RAVER2+FALSEX12_DNASINE,Alu
chr476568676TA0.00051G3BP2-FALSE
chr3170114078AC0.00219SKIL+FALSE
chr1205115428CT4.25965E-05DSTYK-FALSE
chr4129795663TA0.00165JADE1+FALSE
chr1161088583TG0.00822NIT1+FALSE
chr1165404868TG0.00022PCNX3+FALSE
chr119542463TC0.00060LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1936575645GA0.00590WDR62+FALSE
chr540829780TC0.00753.FALSELTR66SINE,Alu
chr6111591610AG0.00105.FALSEFLAM_ASINE,Alu
chr120978304TA0.00018PINK1-AS,DDOST-FALSEAluYSINE,Alu
chr447593283GC0.00110ATP10D+FALSE
chr136755235AG0.00562THRAP3+FALSE
chr342689777TG0.00696NKTR,LOC101928323+,-FALSEMLT1E3SINE,Alu
chr337094679GA7.98870E-06LRRFIP2-FALSE
chr3180694878AT0.00431FXR1+FALSE(T)nSINE,Alu
chr154231849CT0.00812NDC1-FALSE
chr18412989AG0.00190RERE-FALSE
chr136067821TC8.78017E-05PSMB2-TRUEAluSzSINE,Alu
chr1475202402AG0.00141FCF1+TRUEAluScSINE,Alu
chr3188597556AG0.00309LPP+FALSE
chr285773376TC0.00607GGCX-TRUEAluYSINE,Alu
chr1155161737GC0.00482MUC1-FALSE
chr1148753279GT0.00358.FALSE
chr154571380AG0.00332TCEANC2+TRUEAluScSINE,Alu
chr237327685TC0.00057.FALSE
chr1918476232AG0.00189PGPEP1+TRUEAluJbSINE,Alu
chr16283448TC0.00827ICMT-TRUEAluSx3SINE,Alu
chr11647871TC0.00906CDK11B,CDK11A-FALSE
chr119542250TC0.00015LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1142700116CT0.00081ANKRD20A12P-FALSE
chr116200163AG0.00078SPEN+FALSE
chr574072634TA0.00187NSA2+FALSE
chr1541597559AG0.00127.FALSEAluSz6SINE,Alu
chr3112720120TG0.00573GTPBP8+FALSE
chr348787042TC0.00799PRKAR2A-TRUEAluSx3SINE,Alu
chr1610623545TC0.00142EMP2-TRUEAluSpSINE,Alu
chr110521254TC0.00023DFFA-TRUEAluYSINE,Alu
chr6150046495TC0.00076NUP43-TRUEAluSq2SINE,Alu
chr7152343700TC0.00061XRCC2-TRUEAluSx3SINE,Alu
chr1169101257AT0.00144ATP1B1+FALSE
chrX54587254AG0.00019GNL3L+TRUEAluSq2SINE,Alu
chr1120163831AG0.00706ZNF697-FALSE
chr574072648TA0.00036NSA2+FALSE
chr1204524400AG0.00029MDM4+TRUEAluYSINE,Alu
chr19328242AG0.00116H6PD+TRUEAluJrSINE,Alu
chr14834606TC0.00647AJAP1+FALSE
chr1541590982AG0.00327OIP5-AS1+TRUEAluSx1SINE,Alu
chr146828460CT0.00101NSUN4+FALSE
chr116890320TC0.00045NBPF1-FALSE
chr1148004548TC0.00110NBPF8-FALSE
chr1180169330CT0.00015FLJ23867+FALSEMIRSINE,Alu
chr5180682606CA0.00042CTC-338M12.4+FALSE
chr830536583TC0.00031GSR-TRUEAluSpSINE,Alu
chr7127941334CT0.00440MGC27345-FALSEMIR3SINE,Alu
chr1109818158CT0.00212CELSR2+FALSE
chr7131241085GA0.00600PODXL-FALSE(GCA)nSINE,Alu
chr110520174TC0.00158.FALSEAluSxSINE,Alu
chr16283260TC0.00054ICMT-TRUEAluSx3SINE,Alu
chr3127790249AG0.00056RUVBL1,SEC61A1+,-FALSE
chr153288897AG0.00299ZYG11B+TRUEAluJoSINE,Alu
chr145504720GC0.00759ZSWIM5-FALSE
chr1939433140GT0.00260FBXO17-FALSEAluJbSINE,Alu
chrX77083982TC0.00086MAGT1-TRUEAluSzSINE,Alu
chr123636277AT0.00632HNRNPR-FALSE
chr1155851645AG4.46102E-05SYT11+TRUEAluSq2SINE,Alu
chr136067838TC2.61513E-05PSMB2-TRUEAluSzSINE,Alu
chr3195243012AC0.00128PPP1R2-FALSE
chr1675480021TC0.00270TMEM170A-TRUEAluSg4SINE,Alu
chr16682037GA0.00302PHF13+FALSE
chr126755494AG0.00874LIN28A+TRUEAluScSINE,Alu
chr11252687TC0.00459CPSF3L-TRUEAluSpSINE,Alu
chr133071159AG0.00947ZBTB8A+TRUEAluSx1SINE,Alu
chr136067760TC0.00052PSMB2-TRUEAluSzSINE,Alu
chr128825418AG0.00046PHACTR4+TRUEAluSgSINE,Alu
chr5115165731TC5.24208E-07ATG12-TRUEAluSq2SINE,Alu
chr1269237019AG2.84819E-05MDM2+TRUE
chr310976876AG0.00343SLC6A11+FALSE
chr128825427AG0.00484PHACTR4+TRUEAluSgSINE,Alu
chr261369944TC0.00024LOC339803-TRUEAluSxSINE,Alu
chr237478348TA0.00392PRKD3-FALSE
chr261369774TC0.00267LOC339803-TRUEAluSxSINE,Alu
chr286250013TC0.00867LOC90784-TRUEAluSxSINE,Alu
chr286364707GT0.00131PTCD3+FALSE
chr131532312CT0.00215PUM1-FALSE
chr237076498AC0.00797STRN-FALSE
chr145975345AG0.00127MMACHC+TRUEAluSg7SINE,Alu
chr1063954812AC0.00641RTKN2-FALSE
chr1184661932AG0.00063EDEM3-FALSE
chr744918772TC0.00026PURB-FALSEAluSgSINE,Alu
chr197116159GT0.00368INSR-FALSE
chr139470979CA0.00160AKIRIN1+FALSEAluSx1SINE,Alu
chr2178406762GT0.00708AGPS+FALSE
chr261413040TA0.00675AHSA2+FALSE(ATTTTAT)nSINE,Alu
chr339453160GA0.00000RPSA+FALSE
chr5115428334GT0.00265COMMD10+FALSE
chr18413839AG0.00776RERE-FALSE
chr11344893AG0.00186.FALSEAluSgSINE,Alu
chr152381350TG4.39398E-08RAB3B-FALSE
chr1203277242TC0.00023BTG2+FALSE
chr1610625266TC0.00587EMP2-TRUEAluSxSINE,Alu
chr11662764TC0.00505SLC35E2-TRUEAluYSINE,Alu
chr3156258230TC0.00176SSR3-TRUEAluYk3SINE,Alu
chr357913810GA0.00477SLMAP+FALSE
chr11668943AC0.00640SLC35E2-FALSE
chr399463810GT0.00496MIR548G,COL8A1+,-FALSE
chr29629290TG0.00180ADAM17-FALSE(TGT)nSINE,Alu
chr1421929044TC3.48024E-06RAB2B-TRUEAluSpSINE,Alu
chr3194124624CT0.00502ATP13A3-FALSE
chr1022824831CT0.00702PIP4K2A-FALSE
chr210933249CT0.00889PDIA6-FALSE
chr2191184475AG0.00895HIBCH-FALSE
chr2203744240TC0.00595.FALSEAluSxSINE,Alu
chr136530674AG0.00603.FALSEAluSgSINE,Alu
chr3195243007AC3.91570E-06PPP1R2-FALSE
chr111783105AG4.69824E-05.FALSEAluSxSINE,Alu
chr1150548881GA9.52924E-05MCL1-FALSE
chr124786GA0.00285WASH7P-FALSE
chr2043706946AG0.00434STK4+TRUEAluSx4SINE,Alu
chr1569983GA0.00076.FALSE
chr46710356TC0.00046MRFAP1L1-FALSE
chr1145512078AG0.00615NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr18045340CA0.00217PARK7+FALSE
chr174665493GA0.00128FPGT-TNNI3K,FPGT+FALSE
chr1151374016AG0.00822PSMB4+FALSE
chr489181456TC0.00024PPM1K-TRUEAluSx1SINE,Alu
chr1352989863CT0.00132VPS36-FALSE
chr1559428230GA0.00891MYO1E-FALSEMLT1BSINE,Alu
chr1151966348CT0.00511S100A10-FALSE

Differential Expression Gene Analysis