Dataset Overview
RBPPUS1
Knock-MethodshRNA
RBP FamilyPseudoU_synth_1
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR296ERI
PlatformHiSeq
Pubmed ID32252787

PUS1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PUS1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PUS1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr830536078TC0.00509GSR-FALSEAluJrSINE,Alu
chr9140709880CT0.00178EHMT1+FALSE
chr12133298121AG1.85542E-11PGAM5+TRUEAluJoSINE,Alu
chr133149399AG0.00148SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr119499560TC0.00100UBR4-FALSE
chr344791553TC0.00298KIAA1143-TRUEAluJrSINE,Alu
chr1231557255CG0.00056EGLN1-FALSE(GCC)nSINE,Alu
chr3195415493CT0.00126LINC00969,SDHAP2+FALSEL1ME2SINE,Alu
chr127212513TC0.00260GPN2-FALSE
chr2217366570AG0.00332.FALSEAluSzSINE,Alu
chr127992823AC0.00087IFI6-FALSEFAMSINE,Alu
chr744841237TA8.97456E-05PPIA+FALSE
chr1610623544TC2.29348E-06EMP2-TRUEAluSpSINE,Alu
chr1100549715TA0.00765SASS6-FALSE
chr19328120AG0.00024H6PD+TRUEAluJrSINE,Alu
chr116909208CG0.00482NBPF1-FALSE
chr1420940606GA0.00710PNP+FALSE
chr110519148TC0.00611.FALSEAluSx3SINE,Alu
chr3195411498GA0.00722SDHAP2+FALSE
chr1552202957GT0.00094TMOD3+FALSE(T)nSINE,Alu
chr1179044252AG0.00801FAM20B+TRUEAluSxSINE,Alu
chr16730782CT0.00807DNAJC11-FALSE
chr136770602TG0.00441THRAP3+FALSE(T)nSINE,Alu
chr11309464CT3.88389E-12AURKAIP1-FALSE
chr1148561089TC0.00975NBPF15+FALSE
chr159004766GT0.00213OMA1-FALSE
chr410076658TC6.66134E-16WDR1-FALSE
chr5126889370CT0.00713PRRC1+FALSE
chr2174090338AC0.00250ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr12125511242AG0.00015THRIL-FALSEAluSx1SINE,Alu
chr4177252326AG0.00554SPCS3+TRUE
chr1942376675AG0.00085.FALSE
chr7127947979TC0.00257.FALSEAluJrSINE,Alu
chr111785234AG0.00339.FALSEAluJrSINE,Alu
chr7300512GA3.09252E-06FAM20C+FALSE
chr126144435CG4.88757E-05SEPN1+FALSE
chr2200813126TC0.00713TYW5-FALSE
chr120977221AT0.00116PINK1,PINK1-AS+,-FALSE
chr133148691AG0.00207SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr63114457CT0.00320RIPK1+FALSE
chr398298600CT3.56177E-11CPOX-FALSE
chr774169234GT8.95897E-05GTF2I+FALSE
chr2201774264TC0.00099.FALSEAluSzSINE,Alu
chr579923292CG0.00305DHFR-FALSEAluJrSINE,Alu
chr110518052TC0.00831.FALSEAluJrSINE,Alu
chr1760522252GA0.00187METTL2A+FALSE
chr167874689TC0.00053SERBP1-TRUEAluSx3SINE,Alu
chr1109535117CT0.00211WDR47-FALSE
chr1109818161CT0.00382CELSR2+FALSE
chr128826150AG0.00047PHACTR4+TRUEAluJbSINE,Alu
chr116929327CT0.00315NBPF1-FALSEERVL-E-intSINE,Alu
chr128661576AG0.00021MED18+TRUEAluSgSINE,Alu
chr1741133087AG0.00141RUNDC1+FALSE
chr398541116GA1.05300E-07DCBLD2-FALSE
chr116927039CT0.00040NBPF1-FALSE
chr1149913733TC0.00143OTUD7B-TRUEMER96BSINE,Alu
chr3105266274TC4.07026E-07ALCAM+FALSE
chr145244053AG0.00562RPS8+FALSE
chr1788840TC0.00415LINC01128+FALSE
chr110520588TC0.00341.FALSEAluSc8SINE,Alu
chr1453109823TC2.25911E-06ERO1A-TRUEMER53SINE,Alu
chr165898251AT0.00143LEPR,LEPROT+FALSEMIRcSINE,Alu
chr119953120GA0.00027MINOS1,MINOS1-NBL1+FALSE
chr128826085AG0.00153PHACTR4+TRUEAluJbSINE,Alu
chr5125961463AG0.00323PHAX+TRUEAluSz6SINE,Alu
chr3126755556CT0.00303PLXNA1+FALSE
chr6160526910AT0.00672IGF2R+FALSE
chr16282371TC0.00897ICMT-TRUEAluSzSINE,Alu
chr136067817TC1.59583E-06PSMB2-TRUEAluSzSINE,Alu
chr540832557GT5.89786E-05RPL37-FALSE
chr324019989CT0.00339NR1D2+FALSE
chr140219280TC8.82951E-05PPIE+FALSE
chr457326126AG0.00790PAICS+TRUEAluJrSINE,Alu
chr1953914807AG4.44644E-06ZNF765+TRUEAluSpSINE,Alu
chr439551008TC0.00017UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr332496328CA0.00013CMTM7+FALSE
chr146075663AG0.00068NASP+TRUEAluSx4SINE,Alu
chr2133032035TA1.90109E-05SOD1+FALSE
chr133071159AG0.00947ZBTB8A+TRUEAluSx1SINE,Alu
chr11419690AG0.00464ATAD3B+TRUEAluYk2SINE,Alu
chr1571124666CA4.50846E-10LARP6-FALSE
chr224223159AG0.00717UBXN2A+TRUEAluScSINE,Alu
chr133149443AG2.90388E-05SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1117530477GA0.00223PTGFRN+FALSE
chr399463810GT0.00599MIR548G,COL8A1+,-FALSE
chr373115390CT0.00462PPP4R2+FALSE(AT)nSINE,Alu
chr514696117TC0.00807OTULIN+FALSE
chr1179042544AG0.00722FAM20B+TRUEAluSx1SINE,Alu
chr168167935AG0.00390GNG12-FALSE
chr541917720TG0.00727C5orf51+FALSE
chr120978516TC0.00774PINK1-AS,DDOST-FALSEAluYSINE,Alu
chr644222157GA0.00856SLC35B2-FALSE
chr119585917TA0.00308MRTO4+FALSEAluJrSINE,Alu
chr1022824831CT0.00702PIP4K2A-FALSE
chr127202844TC0.00076.FALSEAluSq2SINE,Alu
chr116891333CT0.00011NBPF1-FALSE
chr217962998TA0.01000GEN1+FALSE
chr246839477TC0.00033PIGF-FALSE
chr575469427GA0.00155SV2C+FALSE
chr345721827CA0.00142LIMD1,LIMD1-AS1+,-FALSEAluJbSINE,Alu
chr1757279257AG0.00362PRR11+TRUEAluSq2SINE,Alu
chr12125511942AG0.00596THRIL-FALSEAluSx1SINE,Alu
chr194423353GA0.00057CHAF1A+FALSEGA-richSINE,Alu
chr564964314TC0.00208SGTB-TRUEAluScSINE,Alu
chr116944809GC9.47535E-05CROCCP2-FALSE
chr825222165AG0.00019DOCK5+FALSE
chrX16781186AG0.00220.FALSEAluJoSINE,Alu
chr933046889TA0.00932SMU1-FALSEAluSzSINE,Alu
chr9131872853CG0.00108CRAT-FALSE
chr1748828384GT0.00283LUC7L3+FALSE
chr3188602081AC7.06828E-05LPP+FALSEMIRcSINE,Alu
chr1013320236CT0.00011PHYH-FALSE
chr101086804TA0.00821IDI2-AS1,IDI1+,-FALSE
chr1145512073AG0.00285NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr636894337GA0.00607C6orf89+FALSEGA-richSINE,Alu
chr150883798TC0.00156DMRTA2-FALSE
chr1742877584TC0.00489GJC1-TRUEAluSgSINE,Alu
chr125655853AG0.00147RSRP1,RHD+,-FALSEAluSzSINE,Alu
chr140435513CA0.00656MFSD2A+FALSE
chr250147866GA0.00130NRXN1-FALSE(GT)nSINE,Alu
chr7137612915GA0.00057CREB3L2-FALSE
chr3100083427TA0.00456TOMM70-FALSEFAMSINE,Alu
chr19328213AG0.00404H6PD+TRUEAluJrSINE,Alu
chr286272758GA0.00489POLR1A-FALSE
chr848890288AG0.00210MCM4+TRUEAluJbSINE,Alu
chr299812465AG0.00367MRPL30+TRUEAluSxSINE,Alu
chr11634860GT0.00659CDK11B,CDK11A-FALSE
chr2133974088AG0.00057C21orf59-FALSE
chr19910358TC0.00083CTNNBIP1-FALSE
chr7105162562GC0.00096PUS7-FALSE
chr195658346TA0.00961TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr1146649884TA0.00338PDIA3P1+FALSE
chr310192704AG0.00091VHL+TRUEAluSx1SINE,Alu
chr728860031AT0.00017CREB5+FALSE
chr1179326847AG0.00031SOAT1+TRUEAluJoSINE,Alu
chr110517508TC0.00034.FALSEAluSx1SINE,Alu
chr657034841GT0.00581ZNF451,LOC101927211+,-FALSE
chr2018468339TC0.00062RBBP9-TRUEAluSz6SINE,Alu
chr274645427AG0.00011C2orf81-FALSE
chr716823610TG0.00765TSPAN13+FALSE
chr190152146CT1.61967E-05LRRC8C+FALSE
chr642854664AG5.02680E-07RPL7L1+TRUEAluScSINE,Alu
chr3160969268CT0.00375NMD3+FALSE
chr185785550CA0.00156DDAH1-FALSE
chr1726672364CG0.00645TNFAIP1+FALSE
chr2144329971AG9.72102E-05.FALSEAluSx3SINE,Alu
chr116933135GT2.86961E-06NBPF1-FALSEL1MC2SINE,Alu
chr3156259348GA0.00899SSR3-FALSEAluSq2SINE,Alu
chr1180169330CT0.00374FLJ23867+FALSEMIRSINE,Alu
chr439551140TC1.44695E-08UGDH-AS1,SMIM14+,-FALSEAluSzSINE,Alu
chr167874696TC0.00420SERBP1-TRUEAluSx3SINE,Alu
chr5125961810AG3.92353E-06PHAX+TRUEFLAM_CSINE,Alu
chr2187544218TG0.00796ITGAV+FALSE
chr12125513906CA0.00464.FALSEAluSx1SINE,Alu
chr110519888TC0.00878.FALSEAluJrSINE,Alu
chr9127711532TC0.00018SCAI-TRUEAluSpSINE,Alu
chr345722287AG0.00197LIMD1,LIMD1-AS1+,-FALSEAluSzSINE,Alu
chr145187511TC7.71832E-06C1orf228+FALSEU5SINE,Alu
chr5174956218AG0.00953SFXN1+TRUEAluSpSINE,Alu
chr1779004271TC0.00200BAIAP2-AS1-FALSEAluSq2SINE,Alu
chr1160966352TC1.19601E-07F11R-TRUEAluSgSINE,Alu
chr2025428308AG0.00185GINS1+TRUEAluSzSINE,Alu
chr2239973454TC0.00091HDAC4-FALSE
chr315112612TC0.00634RBSN-TRUEAluSq2SINE,Alu
chr3196670095CA1.97381E-07NCBP2-AS2+FALSE
chr110518591AT0.00030.FALSE
chr19160982TC0.00695.FALSEAluJbSINE,Alu
chr1204525649AG0.00191MDM4+TRUEAluSzSINE,Alu
chr1193466866GT0.00559MIR1304-FALSEAluJrSINE,Alu
chr1064911911AG0.00908NRBF2+FALSE
chr13697550CA0.00078LRRC47-FALSEAluScSINE,Alu
chr1245008386GC0.00041.FALSEMER2SINE,Alu
chr3181430144CT0.00043SOX2-OT,SOX2+FALSE
chr1688789703CG0.00498PIEZO1-FALSE
chr232532809AG0.00255.FALSEAluSx1SINE,Alu
chr1201489569GA0.00145RPS10P7+FALSE
chr19664845CT1.14015E-08TMEM201+FALSE
chr2025427856AG0.00094GINS1+FALSEAluSzSINE,Alu
chr1210025751GA0.00067DIEXF+FALSETigger4aSINE,Alu
chr642855972AG3.93003E-05RPL7L1+TRUEAluSzSINE,Alu
chr120826781CT0.00296MUL1-FALSE
chr441673604TC0.00580LIMCH1+FALSE
chr19162423TC0.00074.FALSEAluSxSINE,Alu
chr124289896TG0.00051PNRC2+FALSE
chr119585553AG4.91829E-14MRTO4+TRUEAluSc8SINE,Alu
chr315296357AT3.39714E-05SH3BP5,SH3BP5-AS1+,-FALSE
chr6158093827CT0.00201ZDHHC14+FALSE
chr175196073CT0.00159CRYZ-FALSE
chr1623536684TC0.00012EARS2-FALSE
chr155319888TG0.00000DHCR24-FALSE
chr1204095426CT0.00481SOX13+FALSE
chr119586532AG7.13982E-05MRTO4+TRUEAluSzSINE,Alu
chr2179368982AC0.00530MIR548N,PLEKHA3+FALSE
chr3183861750AC1.09807E-05EIF2B5+FALSE
chr5133918133AC0.00413JADE2+FALSE
chr116958833TA0.00765.FALSE
chr136068294TC0.00321PSMB2-TRUEAluScSINE,Alu
chr116945570AG0.00131CROCCP2-FALSE
chr193599279GA0.00849MTF2+FALSE
chr1201438098TG2.75480E-05PHLDA3-FALSE
chr311598816CA0.00118ATG7,VGLL4+,-FALSE
chr1203713133GA0.00984ATP2B4+FALSE
chr110240859GT0.00312UBE4B+FALSE
chr145975498AG0.00018MMACHC+TRUEAluSx4SINE,Alu
chr642856045AG0.00428RPL7L1+TRUEAluSzSINE,Alu
chr140539211AT0.00105PPT1-FALSE
chr11252513TC0.00043CPSF3L-TRUEAluSpSINE,Alu
chr110517486TC0.00626.FALSEAluSx1SINE,Alu
chr764435683TA0.00239ZNF117-FALSE
chr136068210TC0.00178PSMB2-TRUEAluScSINE,Alu
chr116893813AG7.34801E-05NBPF1-FALSE
chr4170017406AT0.00534SH3RF1-FALSE
chr1100657416CT0.00228DBT-FALSEAluJbSINE,Alu
chr176252687TC0.00021RABGGTB+FALSE
chr489625427GC0.00025HERC3+FALSE
chr1151092875AG0.00154GABPB2+TRUEAluSpSINE,Alu
chr1152884247AG0.00642IVL+FALSE
chr250147867TA0.00896NRXN1-FALSE(GT)nSINE,Alu
chr1810691357GA0.00082PIEZO2-FALSE
chr438946824CT0.00250FAM114A1+FALSE
chr133149486AG0.00874SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr3196659892TG0.00620SENP5+FALSEAluSzSINE,Alu
chr1120612194CG0.00561NOTCH2-FALSE(CCG)nSINE,Alu
chr556177851AT0.00796MAP3K1+FALSE(CAA)nSINE,Alu
chr1810752666CT1.68498E-05PIEZO2-FALSE
chr11469787CT0.00010ATAD3A+FALSE
chr133086876TC0.00399ZBTB8OS-TRUEAluYSINE,Alu
chr237331750TC0.00067.FALSEAluJbSINE,Alu
chr1245006499CG0.00171COX20+FALSE
chr16651728CT0.00118KLHL21-FALSE
chr110518591AT0.00545.FALSE
chr110520683TC0.00582DFFA-TRUEAluSc8SINE,Alu
chr4109542624GA0.00048RPL34+FALSEMIRbSINE,Alu
chr1254634284TC0.00247CBX5-TRUEAluJrSINE,Alu
chr119943823CA0.00752MINOS1,MINOS1-NBL1+FALSE
chr275882576TC0.00328MRPL19+FALSE
chr76202056GA0.00019CYTH3-FALSE
chr228635740TC0.00358FOSL2+FALSE
chr1161930908GA0.00664ATF6+FALSE
chr147844403CA0.00511CMPK1+FALSE
chr1109818151TC0.00855CELSR2+FALSE
chr11647814TC0.00123CDK11B,CDK11A-FALSE
chr110517691TC9.61087E-05.FALSEAluSx1SINE,Alu
chr23192912GA0.00168TSSC1-FALSE
chr110517276TC0.00779.FALSEAluJrSINE,Alu
chr153366576AG0.00484ECHDC2-FALSEAluJbSINE,Alu
chr11768386TC0.00208PDDC1-TRUEAluScSINE,Alu
chr135223881GA0.00228GJB5+FALSE
chr2206987108TC0.00015.FALSEAluSxSINE,Alu
chr1298943033AG0.00346TMPO+TRUEAluSzSINE,Alu
chr133148196AG0.00529SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr86615608CG0.00017AGPAT5+FALSE
chr2172412008CG0.00982CYBRD1+FALSE
chr642855057AG0.00034RPL7L1+TRUEAluSpSINE,Alu
chr440138676AG0.00157N4BP2+FALSE
chr129041856AG0.00756GMEB1+TRUEAluSq4SINE,Alu
chr145975740CG0.00096MMACHC+FALSEAluSx4SINE,Alu
chr1200941185TG0.00729KIF21B-FALSE
chr8144357975CT0.00444GLI4+FALSE
chr138174987TC0.00350CDCA8+FALSE
chr116889044TA0.00256NBPF1-FALSE
chr1269237020AG0.00378MDM2+TRUE
chr103208557AG0.00128PITRM1-FALSE
chr328390351AG0.00200AZI2-FALSE
chr10124815149CG0.00993ACADSB+FALSETHE1A-intSINE,Alu
chr161921200AT0.00177NFIA+FALSE
chr3195461650AG0.00062.FALSEAluSzSINE,Alu
chr5118174757TC0.00032DTWD2-TRUEAluYSINE,Alu
chr1145689812AG0.00431NBPF20,NBPF10+TRUEAluJbSINE,Alu
chr357542173CT0.00020PDE12+FALSE
chr1492585231TC0.00023NDUFB1-TRUEAluSgSINE,Alu
chr1138266CT0.00802LOC729737-FALSE
chr345960560TA0.00201FYCO1-FALSE
chr553841240AG0.00416SNX18+FALSE
chr319992312AG0.00798RAB5A+FALSE
chr165299558CT0.00161JAK1-FALSE
chr1156163906CT0.00130SLC25A44+FALSE
chr729961437TG6.91541E-06SCRN1-FALSE
chr1077157784CT0.00027ZNF503-FALSE(T)nSINE,Alu
chr35257971CT7.48062E-05EDEM1+FALSE
chr439551975TC5.31269E-07UGDH-AS1,SMIM14+,-FALSEAluSxSINE,Alu
chr1186946912GA0.00414PLA2G4A+FALSE
chr192941357AG0.00296GFI1-FALSE
chr163790503TC0.00289FOXD3+FALSE
chr1232532499AT0.00119.FALSE
chr116892279CA0.00326NBPF1-FALSE
chr5179020622TC2.11448E-05RUFY1+FALSE
chr12133298254AG0.00849PGAM5+TRUEAluSpSINE,Alu
chr116889513TC0.00777NBPF1-TRUEL1MC4SINE,Alu
chr16283448TC0.00827ICMT-TRUEAluSx3SINE,Alu
chr553840199GT0.00857SNX18+FALSE
chr153679610GA0.00073CPT2+FALSEAluSzSINE,Alu
chr47764501TA5.61153E-09AFAP1,AFAP1-AS1+,-FALSE
chr417802824TC0.00594DCAF16-TRUEAluSzSINE,Alu
chr730616247TC0.00887LOC401320-FALSETHE1BSINE,Alu
chr187213182AT0.00072SH3GLB1+FALSE
chr838829416AG0.00695PLEKHA2+TRUEAluYcSINE,Alu
chr2220404381AG0.00268CHPF-FALSE
chr348556339GA6.87729E-06PFKFB4-FALSE
chr116577908GC0.00686FBXO42-FALSE
chr145975266AG0.00345MMACHC+TRUEAluSg7SINE,Alu
chr595236459CT0.00330ELL2-FALSE
chr128825830AG0.00549PHACTR4+TRUEAluSpSINE,Alu
chr6100005419AG2.18273E-06CCNC-FALSEAluSgSINE,Alu
chr146075720AG0.00105NASP+TRUEAluSx4SINE,Alu
chr123833607AT0.00818E2F2-FALSE

Differential Expression Gene Analysis