Dataset Overview
RBPPHF6
Knock-MethodshRNA
RBP FamilyNon-canonical_RBP
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR322XVS
PlatformHiSeq
Pubmed ID32252787

PHF6 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of PHF6
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of PHF6


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr19331227AG0.00181H6PD+TRUEAluSxSINE,Alu
chr16282401TC0.00665ICMT-TRUEAluSzSINE,Alu
chr1118167515CT0.00852FAM46C+FALSE
chr139305021GT0.00046RRAGC-FALSE
chr1544055281TC0.00580PDIA3+FALSE
chr724731065CT0.00414MPP6+FALSE(TGTATG)nSINE,Alu
chr4120219239TA0.00707C4orf3-FALSE
chr3107763040GA1.74111E-05CD47-FALSE
chr339452123GA0.00093RPSA+FALSE
chr190496700AG0.00486ZNF326+FALSE
chr153679610GA0.00084CPT2+FALSEAluSzSINE,Alu
chr1541593268AG0.00084.FALSEAluSz6SINE,Alu
chr3101399945AG0.00965RPL24-FALSE
chr28996326CT0.00077MBOAT2-FALSE
chr146076467AG0.00118NASP+TRUEAluSxSINE,Alu
chr227001973CT0.00327SLC35F6+FALSEAluSxSINE,Alu
chr1144931392GA0.00172NBPF20,PDE4DIP+,-FALSE
chr1220231276TC0.00937RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr1761897188GT0.00465FTSJ3-FALSE
chr1932005AG0.00110.FALSE
chr4142945451TC0.00585.FALSE
chr133071159AG0.00947ZBTB8A+TRUEAluSx1SINE,Alu
chr7128143606AG4.95106E-06.FALSEAluJr4SINE,Alu
chr4113346996GA0.00191ALPK1+FALSE
chr581571271TG0.00827RPS23-FALSE
chr119984346AG0.00071MINOS1-NBL1,NBL1+FALSE
chr572801329TA0.00073BTF3+FALSE
chr1957804719AC0.00361ZNF460+FALSE
chr2231375015AT0.00990TUG1+FALSE
chr625600772AG0.00269CARMIL1+FALSE
chr841399722AG0.00065LOC102723729,GINS4+,-FALSEAluSx3SINE,Alu
chr2110373919GA0.00669SOWAHC+FALSE
chr310192652AG0.00155VHL+TRUEAluSx1SINE,Alu
chr1143915879AC0.00097.FALSE
chr310193797AG0.00199VHL+TRUEAluSxSINE,Alu
chr211323276TC0.00219ROCK2-FALSE
chr1423300663GA0.00120MRPL52+FALSEMIRbSINE,Alu
chr633269307TC0.00645.FALSEAluSxSINE,Alu
chr1153617980AG0.00272CHTOP+FALSE
chr1298942808AG0.00019TMPO+TRUEAluScSINE,Alu
chr110520684TC0.00842DFFA-TRUEAluSc8SINE,Alu
chr116717888GA0.00979SZRD1+FALSE
chr310192785AG0.00741VHL+TRUEAluSx1SINE,Alu
chr1913883923AG0.00493MRI1+TRUEAluSzSINE,Alu
chr16681544TC0.00031PHF13+FALSE
chr11431295TC3.55878E-05ATAD3B+FALSE
chr195362514GT7.06346E-05CNN3-FALSE
chr136068281TC0.00331PSMB2-TRUEAluScSINE,Alu
chr315114759GA0.00595RBSN-FALSE
chr264863970CT9.52027E-09SERTAD2-FALSE
chr1990773CT0.00486AGRN+FALSE
chr2232328545CT0.00581NCL-FALSE
chr8104343686GA0.00031FZD6+FALSE
chr1077807027TC0.00089C10orf11+FALSE
chr1207943285AG0.00011CD46+TRUEAluSx1SINE,Alu
chr1160990906GA0.00270F11R-FALSE
chr1749042216TC0.00746SPAG9-TRUEAluJbSINE,Alu
chr2025428616AG0.00817GINS1+FALSEAluJbSINE,Alu
chr110520378TC0.00047.FALSEAluSx1SINE,Alu
chr2042933642TC0.00275FITM2-TRUEAluJoSINE,Alu
chr116890644CT0.00533NBPF1-FALSE
chr4119555142AG4.95460E-05LOC729218+FALSE
chr128661656AG0.00026MED18+TRUEAluSgSINE,Alu
chr144088547CA0.00927PTPRF+FALSEA-richSINE,Alu
chr1237065326CT0.00376MTR+FALSE
chr346007825TC4.58354E-06FYCO1-FALSE
chr133149486AG5.00374E-05SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr2201253956AG0.00071SPATS2L+FALSE
chr120978324TG0.00153PINK1-AS,DDOST-FALSEAluYSINE,Alu
chr1117531813TC0.00751PTGFRN+FALSE
chr138182333GT0.00063EPHA10-FALSEL2d2SINE,Alu
chr1156163906CT0.00130SLC25A44+FALSE
chr830536143TC0.00883GSR-TRUEAluJrSINE,Alu
chr541919747CT0.00814C5orf51+FALSEL2cSINE,Alu
chr10114209888AG0.00386VTI1A+TRUEAluSx3SINE,Alu
chr636894338AG0.00607C6orf89+FALSEGA-richSINE,Alu
chr237328097TC3.71887E-07.FALSE
chr1326539AG0.00450.FALSE
chr9132268942AG0.00104LINC00963+TRUEAluYf1SINE,Alu
chr642855962AG0.00781RPL7L1+TRUEAluSzSINE,Alu
chr116861804GA0.00903LOC100132147-FALSEtRNA-Glu-GAASINE,Alu
chr110520258TC0.00396.FALSEAluSxSINE,Alu
chr131732602CA0.00336SNRNP40-FALSE
chr2237035915CG0.00348AGAP1+FALSE
chr153711218AT0.00838LRP8-FALSE
chr3100467676AT0.00067TFG+FALSE
chr1765335362TC3.02375E-05PSMD12-TRUEAluSxSINE,Alu
chr136068276TC0.00110PSMB2-TRUEAluScSINE,Alu
chr131732601AT0.00175SNRNP40-FALSE
chr3197611106AG0.00137.FALSEAluSx1SINE,Alu
chr312598618CT0.00812MKRN2+FALSE
chr170610735TC0.00259LRRC40-FALSE
chr119934742GT8.15259E-08MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr1179043553GA0.00238FAM20B+FALSE
chr193803490TC0.00572CCDC18-AS1-FALSEAluJrSINE,Alu
chr1179044239AG0.00143FAM20B+TRUEAluSxSINE,Alu
chr174930749AG0.00025KIF1C+TRUEFLAM_ASINE,Alu
chr5125961011AG0.00075PHAX+TRUEAluSzSINE,Alu
chr1145512073AG0.00505NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr237328034TC5.88540E-05.FALSE
chr128825466AG0.00701PHACTR4+TRUEAluSgSINE,Alu
chr12336210CT0.00206RER1+FALSE
chr146077218AG0.00783NASP+TRUEAluSc8SINE,Alu
chr237328013TC0.00010.FALSE
chr1590819619AG5.14004E-06.FALSEAluSxSINE,Alu
chr1755752444CT0.00000MSI2+FALSE
chr1552840681CT0.00789ARPP19-FALSEAluSx1SINE,Alu
chr1100549715TA0.00765SASS6-FALSE
chr63022544TC7.02821E-06HTATSF1P2-TRUEAluJrSINE,Alu
chr127107950GA0.00249ARID1A+FALSE
chr3109045430GA4.43689E-05DPPA4-FALSE
chr237327614TC0.00035.FALSE
chr1100657416CT0.00058DBT-FALSEAluJbSINE,Alu
chr146033497TC0.00719AKR1A1+FALSEAluYk3SINE,Alu
chr348787042TC1.97898E-05PRKAR2A-TRUEAluSx3SINE,Alu
chr1542503336CT0.00916TMEM87A-FALSE(T)nSINE,Alu
chr2227597697GT0.00890IRS1-FALSE
chr345748599TA0.00470SACM1L+FALSE
chr3179117646GA0.00812GNB4-FALSE
chr2152334421AG0.00464.FALSEAluSqSINE,Alu
chr255255314AC0.00638RTN4-FALSE
chr115990912TC0.00133.FALSEAluSx3SINE,Alu
chr4128958127AG0.00556ABHD18+TRUEAluSx3SINE,Alu
chr1117531621AG0.00577PTGFRN+FALSE
chr19161357TC0.00739.FALSEAluSxSINE,Alu
chr596372165GA0.00149.FALSE
chr825272423GT0.00659DOCK5+FALSE
chr237429626AG0.00028CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr1120162787TC0.00925ZNF697-FALSE
chr138423235CA0.00040SF3A3-FALSEAluJoSINE,Alu
chr317201871TC0.00626TBC1D5-FALSE
chr4119555188CA0.00205LOC729218+FALSE
chr417803616TC0.00046DCAF16-TRUEAluYSINE,Alu
chr1194801636CG0.00522SRSF8+FALSE
chr1352952575GA0.00030THSD1-FALSE
chr146032311AG0.00340AKR1A1+FALSE
chr652860746TG0.00011.FALSE7SKSINE,Alu
chr242577806TA0.00276COX7A2L-FALSE
chr1202993198CA0.00754TMEM183A+FALSE
chr1144598755GA0.00044NBPF20+FALSE
chr1118167515CT3.85037E-05FAM46C+FALSE
chr1623478710CA0.00335GGA2-FALSE(AC)nSINE,Alu
chr11417974CT0.00677ATAD3B+FALSE
chr125889571GA0.00344LDLRAP1+FALSE
chr344791398TC0.00204KIAA1143-TRUEAluJrSINE,Alu
chr2153506056TC0.00252FMNL2+FALSE
chr133148623AG4.79591E-07SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr147843356AT0.00556CMPK1+FALSE
chr1145284175GC0.00562NBPF20,NOTCH2NL+FALSE
chr165901227AT0.00914LEPR,LEPROT+FALSEAluYh3SINE,Alu
chr11152601AG0.00075SDF4-FALSE
chr1015120279TC0.00255ACBD7-TRUEL1PA7SINE,Alu
chr2158170017TC0.00662GALNT5+FALSE
chr11656557TC0.00012SLC35E2-TRUEAluSzSINE,Alu
chr1113455441CA0.00047SLC16A1-FALSE(A)nSINE,Alu
chr1151846854TG0.00626THEM4-FALSEAluSxSINE,Alu
chr224494638TG0.00495ITSN2-FALSE(TATCCT)nSINE,Alu
chr310285030GA0.00384IRAK2+FALSE
chr7129474438CT0.00034UBE2H-FALSE
chr12125511958AG0.00010THRIL-FALSEAluSx1SINE,Alu
chr1145369556AG0.00086NBPF20,NBPF10+TRUEL1MC4SINE,Alu
chr1200375418CT0.00425ZNF281-FALSE
chr1942375627AG0.00463.FALSEAluSxSINE,Alu
chrX77083828TC1.52468E-05MAGT1-TRUEAluSzSINE,Alu
chr4113152490GA0.00221.FALSE
chr1229730452GA0.00236TAF5L-FALSE
chr1765334886TC8.05380E-09PSMD12-TRUEAluSqSINE,Alu
chr126143725AT0.00988SEPN1+FALSEAluSxSINE,Alu
chr146076533AG1.88265E-05NASP+TRUEAluSxSINE,Alu
chr3179117242TC0.00011GNB4-TRUEAluSzSINE,Alu
chr124151858CT0.00104HMGCL-FALSE
chr128662105AG0.00846MED18+TRUEAluSq2SINE,Alu
chr425279508GA3.42130E-11PI4K2B+FALSE
chr2244890573TC1.87764E-05LDOC1L-FALSE
chr126449327AG0.00330PDIK1L+FALSE
chr195660018TA0.00052TMEM56-RWDD3,LOC101928118,TMEM56+,-FALSE
chr224224134AG0.00333.FALSEAluSpSINE,Alu
chr153289686AG0.00460ZYG11B+TRUEAluSzSINE,Alu
chr1182993025CT0.00490LAMC1+FALSE
chr6114181220AG0.00265MARCKS+FALSE
chr1155230131CT0.00829SCAMP3-FALSE
chr1224573601CT0.00587WDR26-FALSE
chr4120979770TC0.00437.FALSEAluSgSINE,Alu
chr136067858GA0.00293PSMB2-FALSEAluSzSINE,Alu
chr175288078AG0.00081RABEP1+FALSE
chr16704652CT1.57063E-06DNAJC11-FALSE
chr1182543666TG0.00124RNASEL-FALSE
chr119953124GA0.00106MINOS1,MINOS1-NBL1+FALSE
chr116890644CT0.00439NBPF1-FALSE
chr5175816758TA0.00528.FALSE
chr1111721354GT0.00616CEPT1+FALSE
chr123419855TC0.00555LUZP1-FALSE
chr344790636TC0.00083KIAA1143-TRUEAluYSINE,Alu
chr153712569CA0.00061LRP8-FALSE(CA)nSINE,Alu
chr131905889AG0.00565SERINC2+FALSE
chr116952298AC2.15086E-05CROCCP2-FALSE
chr136067784TC0.00821PSMB2-TRUEAluSzSINE,Alu
chr2188330198CA0.00091TFPI-FALSEAluJbSINE,Alu
chr46718811AG1.36854E-07BLOC1S4+FALSEFLAM_ASINE,Alu
chr1225707042TC4.11654E-05ENAH-FALSE
chr2198572082TC0.00093MARS2+FALSE
chr111347154AT0.00441UBIAD1+FALSE
chr1247319489GA0.00729ZNF124-FALSE
chr1142688707AC0.00504.FALSE
chr1204526713AG0.00078MDM4+TRUEAluSxSINE,Alu
chr2201842492TC0.00107FAM126B-TRUEAluJbSINE,Alu
chr152498140GA0.00044TXNDC12,KTI12-FALSE
chr3196044972CT0.00258TCTEX1D2,TM4SF19-TCTEX1D2-FALSE
chr7128829066AG0.00816SMO+FALSE
chr345960558CT6.37727E-08FYCO1-FALSE
chr315456307TC0.00939METTL6-TRUEAluJrSINE,Alu
chr1765335394TC5.10125E-06PSMD12-TRUEAluSxSINE,Alu
chr730544360GA0.00170GGCT-FALSE
chr123835919CT0.00872E2F2-FALSE
chr136068325TC0.00746PSMB2-TRUEAluScSINE,Alu
chr110437995GA0.00427KIF1B+FALSEAluSgSINE,Alu
chr136068276TC2.73596E-05PSMB2-TRUEAluScSINE,Alu
chr140539201AG0.00028PPT1-FALSE
chr1727586605GA0.00053NUFIP2-FALSE
chr2201842323TC0.00390FAM126B-TRUEAluJbSINE,Alu
chr153250625TC0.00178ZYG11B+FALSE
chr194995411CA0.00849F3-FALSEAluSxSINE,Alu
chr139500293TA0.00552NDUFS5+FALSE
chr19161142TC8.95302E-05.FALSEAluSxSINE,Alu
chr611185161CT0.00297NEDD9-FALSE
chr646128910AG0.00782ENPP5-FALSE(GT)nSINE,Alu
chr2201774264TC0.00099.FALSEAluSzSINE,Alu
chr11597403CT0.00912CDK11B,SLC35E2B-FALSE
chr136068369TC0.00404PSMB2-TRUEAluScSINE,Alu
chr13545192CG0.00332TPRG1L+FALSE
chr1919459215CT0.00068MAU2+FALSE
chr342592874TC9.28376E-05SEC22C-FALSEAluJrSINE,Alu
chr1540712737TC0.00525IVD+FALSE
chr811666384CT0.00029FDFT1+FALSE
chr110520505TC0.00011.FALSEAluSx1SINE,Alu
chr18413839AG0.00776RERE-FALSE
chr16583066TC0.00088NOL9-TRUEAluSx4SINE,Alu
chr1112003957GA0.01000ATP5F1+FALSEHelitron2Na_MamSINE,Alu
chr3122283290GC0.00029DTX3L,PARP9+,-FALSE
chr116576291AG0.00842FBXO42-FALSEA-richSINE,Alu
chr29630247TG0.00638ADAM17-FALSE
chr1101354038TC0.00565EXTL2-TRUEL1MB2SINE,Alu
chr119543459TC0.00540LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr2109401286GT0.00087RANBP2+FALSE
chr348787042TC0.00799PRKAR2A-TRUEAluSx3SINE,Alu
chr4128756738AG0.00408.FALSEAluSxSINE,Alu
chr119586520AG0.00846MRTO4+TRUEAluSzSINE,Alu
chr1114307293AG0.00499RSBN1-FALSE
chr598128999GA0.00663RGMB+FALSE
chr1490509564CT0.00552TDP1+FALSE
chr16283548AG0.00286ICMT-FALSE
chr110093457CT0.00777UBE4B+FALSE
chr120976023TC6.30669E-06PINK1,PINK1-AS+,-FALSEAluSzSINE,Alu
chr19328213AG0.00404H6PD+TRUEAluJrSINE,Alu
chr1953999034AG0.00282.FALSEAluSq2SINE,Alu
chr312628920GC0.00036RAF1-FALSE
chr310192784AG1.73909E-05VHL+TRUEAluSx1SINE,Alu
chr729960812TA1.34773E-06SCRN1-FALSE
chr124865333AG0.00087.FALSEFLAM_ASINE,Alu
chr128566404TG0.00963.FALSEAluSx1SINE,Alu
chr120826781CT9.86003E-06MUL1-FALSE
chr1204524457AG6.02506E-06MDM4+TRUEAluYSINE,Alu
chr1646614656TA0.00565SHCBP1-FALSE
chr1179327010AG0.00085SOAT1+TRUE
chr133148096AG0.00404SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr147142539TA0.00066EFCAB14-AS1,EFCAB14+,-FALSE
chr7129472355GC0.00246UBE2H-FALSE
chr310193796AG0.00291VHL+TRUEAluSxSINE,Alu
chr1145441841AT0.00636NBPF20,NBPF10,TXNIP+FALSE
chr116889639TC0.00350NBPF1-TRUE
chr128662053GA0.00158MED18+FALSEAluSq2SINE,Alu
chr425749196TA0.00870SEL1L3-FALSE
chr187811249TA0.00653LMO4+FALSE
chr1563616883AT0.00036CA12-FALSE
chr261416411TG0.00146USP34-FALSEAluSc8SINE,Alu
chr837613073AC0.00394ERLIN2+FALSE(CCCCCAC)nSINE,Alu
chr5149823789GT0.00793.FALSE
chr1232532499AT0.00119.FALSE
chr155062960GA0.00542ACOT11+FALSE
chr617557412CT0.00986CAP2+FALSE
chr1100657416CT0.00102DBT-FALSEAluJbSINE,Alu
chr1610625406TC1.26372E-11EMP2-TRUEAluSxSINE,Alu
chr18413129GA0.00040RERE-FALSE
chr1201846616CG0.00209IPO9+FALSE(CA)nSINE,Alu
chr1165877575AC0.00675UCK2+FALSE
chr138327700TC0.00132INPP5B-TRUEAluSx3SINE,Alu
chr2191556847GT9.96724E-06NAB1+FALSE
chr1117532509CA0.00521PTGFRN+FALSE
chr2113334357GA8.00796E-05POLR1B+FALSEAluSzSINE,Alu
chr286248309TC0.00808LOC90784-FALSE
chr5179048585TC0.00150HNRNPH1-FALSE
chr1148558170TC0.00235.FALSEAluJbSINE,Alu
chr838829839AG0.00184PLEKHA2+TRUEAluJr4SINE,Alu
chr1772784932GA0.00444TMEM104+FALSE
chr1181026558GA0.00217MR1+FALSE
chr39517369CT0.00395SETD5+FALSE
chr16161108CA0.00071KCNAB2+FALSE
chr132953296AG5.26589E-05ZBTB8B+TRUEAluSzSINE,Alu
chr4120979190TC0.00970.FALSEAluSg4SINE,Alu
chr1118502757GA0.00793WDR3,SPAG17+,-FALSE(GT)nSINE,Alu
chr1235492546TG0.00786GGPS1+FALSE

Differential Expression Gene Analysis