Dataset Overview
RBPSRSF1
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR066VOO
PlatformHiSeq
Pubmed ID32252787

SRSF1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of SRSF1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of SRSF1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1990806GA0.00432AGRN+FALSE
chr1111489903AC0.00666LRIF1-FALSE
chr1145509570AG0.00037NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr1143399383TA0.00198.FALSEL1MC4SINE,Alu
chr1772784932GA0.00444TMEM104+FALSE
chr373115390CT0.00462PPP4R2+FALSE(AT)nSINE,Alu
chr13550061AC0.00000WRAP73-FALSE
chr314183410TC1.62266E-06TMEM43+FALSE
chr124134721TC0.00113HMGCL-FALSE
chr16747230CG0.00269FBXL16-FALSE
chr1671765443CT0.00223AP1G1-FALSE
chr110042988AG0.00359NMNAT1+TRUEAluScSINE,Alu
chr1145688944AG0.00359NBPF20,NBPF10,RNF115+TRUEAluSc8SINE,Alu
chr126604691GC0.00043CEP85+FALSE
chr2118854108AT0.00568INSIG2+FALSE
chr14100762690TC0.00461SLC25A29-TRUEAluJoSINE,Alu
chr28998555GA0.00584MBOAT2-FALSE
chr1156613401TC5.47226E-05BCAN+FALSE
chr2217366919AG0.00615.FALSEAluSz6SINE,Alu
chr1117532509CA0.00521PTGFRN+FALSE
chr19163400TC0.00726.FALSEAluSpSINE,Alu
chr1203711876GA0.00444ATP2B4+FALSE
chr10129216658TC0.00710DOCK1+FALSE
chr11421186CT0.00834ATAD3B+FALSE
chr12131356731TC2.96756E-07RAN+FALSE(GGCCGG)nSINE,Alu
chr23609064GA0.00614RNASEH1-AS1+FALSEMER33SINE,Alu
chr3196555443CA3.82991E-09PAK2+FALSE
chr116890130AC0.00728NBPF1-FALSE
chr112628188TC6.05765E-06DHRS3-FALSE
chr9137330713TG0.00021RXRA+FALSE
chr1320247038AG0.00391MPHOSPH8+TRUEAluJbSINE,Alu
chr237330517TC0.00324.FALSEAluSq2SINE,Alu
chr72294401AG0.00035SNX8-FALSE
chr116918502AG0.00098NBPF1-FALSE
chr1194606941TC0.00699AMOTL1+FALSE
chr2174086933CA0.00457ZAK,MLK7-AS1+,-FALSEAluJoSINE,Alu
chr1681744038TC6.34278E-05CMIP+FALSE(CCGC)nSINE,Alu
chr799636947AG0.00851ZKSCAN1+FALSEAluSx1SINE,Alu
chr13548832GC0.00051WRAP73-FALSE
chr126143697GC0.00778SEPN1+FALSE
chr1158066834AG0.00609KIRREL+FALSE
chr3179117280TC0.00624GNB4-TRUEAluSzSINE,Alu
chr357913810GA0.00477SLMAP+FALSE
chr124022437AG0.00342RPL11+FALSE
chr133149508AG0.00871SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr3160154971TC0.00820TRIM59-FALSEAluJbSINE,Alu
chr1172411768TC0.00416C1orf105,PIGC+,-FALSE
chr2113334414AG0.00281POLR1B+TRUEAluSzSINE,Alu
chr356703746AC0.00027FAM208A-FALSE
chr121070971GA0.00944HP1BP3-FALSE
chr1264842920AG2.84792E-05.FALSEAluSzSINE,Alu
chr856985611AT0.00028RPS20-FALSE
chr1167765170GT0.00185UNC93B1-FALSE
chr11431295TC3.55878E-05ATAD3B+FALSE
chr697592894AC0.00654MMS22L-FALSE
chr1173836602GA0.00886GAS5-FALSEAluSxSINE,Alu
chr118808465TA0.00957KLHDC7A+FALSE
chr12109886822AC0.00406KCTD10-FALSE
chr167451521AT0.00049MIER1+FALSE
chr1179045500CA0.00043FAM20B+FALSE
chr1110566210TA0.00832AHCYL1+FALSE
chr138423235CA0.00040SF3A3-FALSEAluJoSINE,Alu
chr138275432GT0.00536MTF1-FALSE
chr1958356524AG0.00026ZNF587B+TRUEAluSxSINE,Alu
chr126143698TA0.00832SEPN1+FALSE
chr1476680377TA0.00143.FALSEL1M5SINE,Alu
chr63021492AG0.00613HTATSF1P2-FALSETigger3aSINE,Alu
chr1205129319GA0.00177DSTYK-FALSE
chr1145689566AG0.00331NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr237328016TC0.00473.FALSE
chr399517466GA0.00088MIR548G-FALSE(TG)nSINE,Alu
chr111089869AG0.00839MASP2-FALSEAluSpSINE,Alu
chr1490865627TC0.00162CALM1+FALSE
chr349067809TA0.00022QRICH1-FALSE
chr3196612193AG7.35500E-07SENP5+FALSE
chr128661657AG0.00011MED18+TRUEAluSgSINE,Alu
chr139471000GA0.00518AKIRIN1+FALSE
chr339452123GA0.00093RPSA+FALSE
chr399517479TC8.06312E-05MIR548G-FALSE(TG)nSINE,Alu
chr97798518GC0.00423TMEM261-FALSE
chr3141667460TG0.00193TFDP2-FALSE
chr9115447533TC0.00326INIP-TRUEAluJbSINE,Alu
chr1163309219AT0.00023NUF2+FALSE
chr179109353GT0.00214IFI44L+FALSELTR26SINE,Alu
chr2045839076AT0.00178ZMYND8-FALSE(T)nSINE,Alu
chr145187511TC7.71832E-06C1orf228+FALSEU5SINE,Alu
chr1765334846TC0.00456PSMD12-FALSEAluSqSINE,Alu
chr456295160TA0.00576CLOCK-FALSE(T)nSINE,Alu
chr1120162587GA0.00730ZNF697-FALSE
chr187211940AC0.00164SH3GLB1+FALSE
chr2675831GT0.00731TMEM18-FALSE
chr6160101723TC0.00234SOD2-TRUEAluSzSINE,Alu
chr146126142GC0.00171GPBP1L1-FALSE
chr1163394016TC0.00106ATL3-FALSE
chr246612338TG0.00018EPAS1+FALSE
chr1247319489GA0.00729ZNF124-FALSE
chr3197611048AG0.00064.FALSEAluSx1SINE,Alu
chr154231849CT0.00812NDC1-FALSE
chr17980667TC0.00584TNFRSF9-TRUEAluJbSINE,Alu
chr314986098TC3.23580E-05FGD5-AS1-TRUEFLAM_CSINE,Alu
chr237331565TC0.00121.FALSEAluJbSINE,Alu
chr3160219095GA0.00620KPNA4-FALSEA-richSINE,Alu
chr121808159GA0.00011NBPF3+FALSE
chr568850922GC0.00323OCLN+FALSEAluSx4SINE,Alu
chr3105258861AG0.00030ALCAM+FALSE
chr5125961463AG0.00323PHAX+TRUEAluSz6SINE,Alu
chr1075008731TC8.90942E-06DNAJC9-AS1,MRPS16+,-FALSEAluJrSINE,Alu
chr5126171974CT0.00867LMNB1+FALSE
chr261277463AG0.00826PEX13+TRUEAluSxSINE,Alu
chr1464152514TC1.52259E-06SGPP1-TRUE(TA)nSINE,Alu
chr1179044110AG5.39593E-06FAM20B+TRUEAluSxSINE,Alu
chr572876776CA0.00875UTP15+FALSE
chr729961437TG6.91541E-06SCRN1-FALSE
chr110517314TC0.00288.FALSEAluJrSINE,Alu
chr19200571TC0.00079LINC01002-FALSE
chr116889624TC0.00795NBPF1-TRUE
chr1145511958AG0.00038NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr136770950AG0.00118THRAP3+FALSE
chr116133912TC0.00126UQCRHL-TRUE
chr386991597TG0.00481VGLL3-FALSE
chr1148251079TC0.00880NBPF8,NBPF14,NBPF9-FALSEL1MC4SINE,Alu
chr5159520661TC0.00776PWWP2A-FALSE
chr1145292925CT0.00817NBPF20+FALSE
chr145975345AG0.00227MMACHC+TRUEAluSg7SINE,Alu
chr1590627429TC0.00013IDH2-FALSE
chr3123332546CG0.00964MYLK-AS1,MYLK+,-FALSE
chr1206566048GC0.00125SRGAP2+FALSE
chr1115313051TC0.00853SIKE1-FALSE
chr1205687344CT0.00633NUCKS1-FALSE(T)nSINE,Alu
chr143897496GA0.00481SZT2+FALSE
chr1292537702TA0.00368BTG1-FALSE
chr1688789699AC0.00936PIEZO1-FALSE
chr145975673AG0.00827MMACHC+TRUEAluSx4SINE,Alu
chr310193743TC0.00456VHL+FALSEAluJrSINE,Alu
chr287777087TC0.00737LINC00152+FALSE
chr1110023610GA0.00636SYPL2+FALSE
chr452888499GA8.91315E-05SGCB-FALSE
chr1157092835GA0.00595.FALSE
chr128662253AG0.00117MED18+TRUEAluSq2SINE,Alu
chr127108139AT0.00683ARID1A+FALSE
chr16283439TC0.00786ICMT-TRUEAluSx3SINE,Alu
chr110521172TC1.01590E-06DFFA-TRUEAluYSINE,Alu
chr1207942509AG0.00177CD46+TRUEAluSg4SINE,Alu
chr1143398850GT0.00639.FALSE
chr110043002AG0.00247NMNAT1+TRUEAluScSINE,Alu
chr110519936TC0.00072.FALSEAluJrSINE,Alu
chr111083183GT0.00342TARDBP+FALSE
chr72473761TC0.00126CHST12+FALSE(CCGC)nSINE,Alu
chr1101444065TC0.00927SLC30A7+FALSEMIR3SINE,Alu
chr11684346GC0.00504NADK-FALSE
chr315112501TC2.98131E-05RBSN-TRUEAluSq2SINE,Alu
chr197085418AG6.02730E-06ZNF557+TRUEAluJbSINE,Alu
chr1749042325TC0.00798SPAG9-TRUEAluJbSINE,Alu
chr29629290TG0.00180ADAM17-FALSE(TGT)nSINE,Alu
chr133149443AG0.00897SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1204524840AG0.00557MDM4+TRUEAluSxSINE,Alu
chr110520819TC0.00022DFFA-TRUEAluSc8SINE,Alu
chr210586904CT0.00041ODC1,SNORA80B-FALSE
chr1212254067GA0.00714DTL+FALSE
chr477996987TC0.00240CCNI-FALSE
chr11459332GA1.33172E-08ATAD3A+FALSE
chr1154128835GT0.00032TPM3-FALSE
chr110520076TC0.00075.FALSEAluSxSINE,Alu
chr2130807905GT0.00634FAR2P1-FALSE
chr3160969268CT0.00835NMD3+FALSE
chr466439443TC0.00593EPHA5-FALSE
chr2043707842AG0.00100STK4+TRUEAluJbSINE,Alu
chr642856029AG7.18756E-05RPL7L1+TRUEAluSzSINE,Alu
chr5125962354AG3.71532E-05PHAX+TRUEAluScSINE,Alu
chr11252468TC0.00096CPSF3L-TRUEAluJrSINE,Alu
chr618264355GA0.00872DEK-FALSE
chr2204301753TA0.00012RAPH1-FALSE
chr261150192CA0.00436REL+FALSEAluSz6SINE,Alu
chr226613949AG0.00669EPT1+FALSE
chr119586501AG0.00055MRTO4+TRUEAluSzSINE,Alu
chr679647408TG0.00561PHIP-FALSE
chr132641383CA0.00112KPNA6+FALSEAluSx3SINE,Alu
chr119655758TA0.00044PQLC2+FALSEAluSzSINE,Alu
chr1117532790CT0.00981PTGFRN+FALSE
chr147840953AG0.00404CMPK1+FALSE
chr72274221TC0.00579MRM2-TRUEAluJrSINE,Alu
chr19163290TC0.00016.FALSEAluSpSINE,Alu
chr129519712TC0.00017MECR-TRUEAluJbSINE,Alu
chr633377511TC5.31992E-06.FALSE(TG)nSINE,Alu
chr5122359499CA0.00304PPIC-FALSE(AC)nSINE,Alu
chr115394286CG0.00260KAZN+FALSE
chr352288956AT0.00042WDR82-FALSE
chr540832548AT0.00048RPL37-FALSE
chr1615794312CT0.00796NDE1+FALSEAluSzSINE,Alu
chr2101623611AC0.00826RPL31+FALSE
chr1160967755CT0.00563F11R-FALSE(T)nSINE,Alu
chr19160900TC0.00542.FALSEAluJbSINE,Alu
chr1144618144AG0.00725NBPF20,NBPF9+FALSE
chr1112258252AG0.00224RAP1A+FALSE
chr1134370TC0.00327.FALSEAluSgSINE,Alu
chr12109887765TG0.00091KCTD10-FALSE
chr237327685TC6.61966E-05.FALSE
chr12125267857TC0.00702SCARB1-TRUEFRAMSINE,Alu
chr145976269CG0.00039MMACHC+FALSE
chr347627382AT2.68370E-06SMARCC1-FALSE
chr246852033AG0.00543CRIPT+FALSE
chr146076467AG0.00475NASP+TRUEAluSxSINE,Alu
chr119934793GA0.00376MINOS1,MINOS1-NBL1,RPS14P3+FALSE
chr7300513TC2.92808E-06FAM20C+FALSE
chr124861704GA0.00345RCAN3+FALSE
chr13730332TC9.76659E-06CEP104-TRUEAluSx3SINE,Alu
chr110521254TC0.00640DFFA-TRUEAluYSINE,Alu
chr19161218TC0.00581.FALSEAluSxSINE,Alu
chr194995653AC0.00035F3-FALSEAluSxSINE,Alu
chr1145116149TA0.00585NBPF20,SEC22B+FALSE
chr193540006TC3.25622E-05C19orf71+FALSEAluJoSINE,Alu
chr5141690772CT0.00632SPRY4-FALSE
chr9136209397GC0.00709MED22-FALSE
chrM9756GA0.00315.FALSE
chr2218572742AG8.48972E-05PEX26+TRUEAluYf1SINE,Alu
chr2114718893CG0.00631ACTR3+FALSE
chr192917287CA0.00243ZNF57+FALSE
chr11595539TC0.00053CDK11B,SLC35E2B-TRUEAluJrSINE,Alu
chr8117858601TA0.00891RAD21-FALSE
chr131732601AT0.00479SNRNP40-FALSE
chr1765335394TC5.10125E-06PSMD12-TRUEAluSxSINE,Alu
chr199673275TC0.00081.FALSETigger1SINE,Alu
chr238971641TA0.00071SRSF7-FALSE
chr1541590288GT0.00349OIP5-AS1+FALSE
chr8144681777GT0.00383TIGD5+FALSE
chr16582470TC0.00370NOL9-TRUEAluSx1SINE,Alu
chr1179843781TC0.00888TOR1AIP2-TRUEAluJbSINE,Alu
chr148764419CT0.00478SPATA6-FALSE
chr2171850175GT0.00054TLK1-FALSE
chr1154179193AT0.00122C1orf43-FALSE
chr1120163248GA0.00711ZNF697-FALSE
chr119543457TC4.71011E-07LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr310192744AG3.36147E-05VHL+TRUEAluSx1SINE,Alu
chr146075783AG0.00755NASP+TRUEAluSx4SINE,Alu
chr1946214293CT0.00137FBXO46-FALSE
chr537290323TC0.00029.FALSEAluSzSINE,Alu
chr167874705TC0.00015SERBP1-TRUEAluSx3SINE,Alu
chr111181327CT0.00573MTOR-FALSE
chr1544751338GA0.00374CTDSPL2+FALSE
chr1179042701AG0.00132FAM20B+TRUEAluSx1SINE,Alu
chr2170403030TC0.00294FASTKD1-FALSE
chr2236883967TC0.00051FOXRED2-TRUEAluSq2SINE,Alu
chr1450053316TC0.00115.FALSE7SLRNASINE,Alu
chr110520702TC0.00883DFFA-TRUEAluSc8SINE,Alu
chr1919745479CT0.00175GMIP-FALSE
chr344791554TC7.29341E-07KIAA1143-FALSEAluJrSINE,Alu
chr1109818158CT4.51493E-05CELSR2+FALSE
chr413602231GA0.00646BOD1L1-FALSE
chr2025427856AG0.00094GINS1+FALSEAluSzSINE,Alu
chr121808159GA9.34000E-05NBPF3+FALSE
chr110517659TC0.00679.FALSEAluSx1SINE,Alu
chr8146280802CT1.51873E-05C8orf33+FALSELTR13SINE,Alu
chrX119572534CA0.00387LAMP2-FALSE
chr274332840GC4.77205E-06TET3+FALSE
chr2232319613CT0.00022NCL-FALSE
chr2208619315AG0.00091CCNYL1+TRUEEutTc1-N1SINE,Alu
chr16282237TC0.00372ICMT-TRUEAluSzSINE,Alu
chr2277003AG1.77913E-11ACP1+FALSE
chr3179042910AG0.00061ZNF639+TRUEAluSpSINE,Alu
chr2208619320AG0.00339CCNYL1+FALSEEutTc1-N1SINE,Alu
chr8144940327GA0.00989EPPK1-FALSE
chr57878179CT0.00014MTRR+FALSE
chr3195243023AC0.00729PPP1R2-FALSE
chr153679610GA0.00084CPT2+FALSEAluSzSINE,Alu
chr1145290818CG0.00287NBPF20+FALSE
chr535058804AT0.00836PRLR-FALSE
chr436121334CG0.00057ARAP2-FALSE
chr1490509564CT0.00552TDP1+FALSE
chr117766126AG0.00017RCC2-FALSE
chr310192672GA5.82875E-07VHL+FALSEAluSx1SINE,Alu
chr145976147GA0.00476MMACHC+FALSEAluJrSINE,Alu
chr2179371305AG0.00696MIR548N+FALSE
chr126799971TA0.00713HMGN2+FALSE
chr248025764CT0.00810MSH6+FALSE
chr5118174668TC1.32199E-05DTWD2-TRUEAluYSINE,Alu
chr11118947634CT0.00276VPS11+FALSE
chr2217366541AG0.00071.FALSEAluSzSINE,Alu
chr1753470462CT0.00230MMD-FALSE
chr534906661TC9.12853E-06RAD1-TRUEAluJoSINE,Alu
chr1656510334TC0.00494OGFOD1+FALSE
chr12123346999TA0.00838HIP1R+FALSE
chr167518534CT0.00030SLC35D1-FALSE
chr14103372469AC0.00683TRAF3+FALSE(AC)nSINE,Alu
chr1118502767GA0.00624WDR3,SPAG17+,-FALSE(GT)nSINE,Alu
chr1541597437TA0.00217.FALSEAluSz6SINE,Alu
chr127216740GA0.00801GPN2-FALSE
chr273460314CT0.00333PRADC1-FALSE(CGGCGC)nSINE,Alu
chr126755209AG0.00745LIN28A+FALSEAluSx1SINE,Alu
chr1946289409CT6.23760E-05DMWD-FALSE
chr1075010139TC0.00323DNAJC9-AS1,MRPS16+,-FALSEAluScSINE,Alu
chr340503555AT0.00177RPL14+FALSE
chr417804847TC0.00512DCAF16-TRUEAluSxSINE,Alu
chr569497703GA0.00557SMA4-FALSE
chr1045499895GA0.00255ZNF22+FALSE
chr1145689537AG0.00028NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr6150047370TC0.00154NUP43-TRUEAluScSINE,Alu
chr345125417GA0.00024CDCP1-FALSEAluJbSINE,Alu
chr540832555AT0.00347RPL37-FALSE
chr1419684445AG0.00351DUXAP10+FALSE
chr3150345451AG2.37481E-05SELT+TRUE
chr167874731TC0.00125SERBP1-TRUEAluSx3SINE,Alu
chr8146035211TC0.00116ZNF517+FALSEAluSx1SINE,Alu
chr224227357AG0.00295.FALSEAluScSINE,Alu
chr2239415796AT0.00084.FALSEMER49SINE,Alu
chr1205739266CT0.00069RAB29-FALSE
chr1716344882TG0.00060LRRC75A-AS1+FALSEAluJbSINE,Alu
chr1912742290AG0.00564.FALSEAluSxSINE,Alu
chr5154194456GC0.00831LARP1+FALSE
chr110517485TC0.00260.FALSEAluSx1SINE,Alu
chr1179044181AG0.00083FAM20B+TRUEAluSxSINE,Alu
chr4128958127AG0.00556ABHD18+TRUEAluSx3SINE,Alu
chr1121133733GA0.00455SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr116912014AC0.00704NBPF1-FALSE
chr237331037TC0.00026.FALSEAluSx1SINE,Alu
chr154354935GC0.00831YIPF1-FALSE
chr174840811AG0.00554SLC25A11-FALSE
chr358304244GA0.00560RPP14+FALSEAluSzSINE,Alu

Differential Expression Gene Analysis