Dataset Overview
RBPASCC1
Knock-MethodshRNA
RBP FamilyAKAP7_NLS
Biosample NameHepG2
Tissue TypeLiver
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR193FFA
PlatformHiSeq
Pubmed ID32252787

ASCC1 - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of ASCC1
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of ASCC1


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr576372541GC0.00498ZBED3-FALSE
chr352084404AT0.00032DUSP7-FALSE(A)nSINE,Alu
chr3183209052TC0.00041KLHL6-TRUEAluSqSINE,Alu
chr1148561089TC0.00975NBPF15+FALSE
chr1145512073AG0.00505NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr696054540GT0.00358MANEA+FALSE
chr153679610GA0.00084CPT2+FALSEAluSzSINE,Alu
chr1145509493AG0.00264NBPF20,NBPF10,RBM8A+TRUEAluJrSINE,Alu
chr125570549CA0.00387RSRP1-FALSE
chr8100890376GT0.00920COX6C-FALSE
chr126138325GA0.00245SEPN1+FALSE
chr1953914807AG4.44644E-06ZNF765+TRUEAluSpSINE,Alu
chr1100361925GA0.00181AGL+FALSE
chr110518052TC7.90759E-05.FALSEAluJrSINE,Alu
chr1210311392TC0.00177OLR1-FALSE
chr237429627AG7.56792E-05CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chrM10307AC0.00046.FALSE
chr1079570873GT0.00292DLG5-FALSE
chr136529575AG2.40551E-05.FALSEAluJrSINE,Alu
chr1204526727AG0.00033MDM4+TRUEAluSxSINE,Alu
chr1246829742TC0.00960CNST+FALSE(TGTG)nSINE,Alu
chr350686350TG2.12445E-05MAPKAPK3+FALSE
chr1153720690GA0.00550INTS3+FALSE
chr1144606838AG0.00988NBPF20+FALSE
chr4129795661AT0.00165JADE1+FALSE
chr1453242425TC0.00473GNPNAT1-TRUEAluJoSINE,Alu
chr1773774199CT0.00056H3F3B-FALSE
chr339438321AT6.25124E-06SLC25A38+FALSE
chr136068237TC0.00075PSMB2-TRUEAluScSINE,Alu
chr228636644AG0.00918FOSL2+FALSE
chr11684347CT0.00550NADK-FALSE
chr9137330714AC0.00030RXRA+FALSE
chr165299551GT0.00292JAK1-FALSE
chr119981865AG0.00213MINOS1-NBL1,NBL1+FALSE
chr2131906031CT0.00439PLEKHB2+FALSE
chr110518733TC0.00050.FALSEAluSx1SINE,Alu
chr4103183510CT0.00718SLC39A8-FALSE
chr247129284AG0.00327MCFD2-FALSE
chr310192596AG9.40892E-06VHL+TRUEAluSx1SINE,Alu
chr167874859TC0.00027SERBP1-TRUEAluSxSINE,Alu
chr2025427756AG0.00396GINS1+TRUEAluSzSINE,Alu
chr132557486AG0.00525TMEM39B+FALSE
chr5180682612AT0.00235CTC-338M12.4+FALSE
chr1252710715GA0.00729KRT83-FALSE
chr3195694465TC0.00300SDHAP1-FALSE
chr11573181CA0.00038CDK11B-FALSE
chr1688767769GC0.00420RNF166-FALSE
chrX54587218AG0.00014GNL3L+TRUEAluSq2SINE,Alu
chr19162932AT0.00635.FALSE
chr720178460TC6.50978E-05MACC1,LOC101927668-TRUEAluYSINE,Alu
chrX123046306AG0.00016XIAP+TRUEAluJbSINE,Alu
chr153289852AG0.00228ZYG11B+TRUEFRAMSINE,Alu
chr117733268TC0.00472RCC2-FALSE
chr1222906426TC0.00322BROX+FALSEAluSxSINE,Alu
chr1146650289CT0.00024PDIA3P1+FALSE
chr634254565AT0.00617.FALSE(A)nSINE,Alu
chr3125248854AC0.00014OSBPL11-FALSE
chr2239259540GA0.00493CBX6-FALSE
chr146774813CG0.00766UQCRH+FALSE
chr237328042TC6.80414E-06.FALSE
chr1939926509AC0.00986RPS16-FALSE
chr1144618201TC2.48995E-05NBPF20,NBPF9+FALSE
chr194654601AG0.00016TNFAIP8L1+TRUEAluJbSINE,Alu
chr1214527252GA0.00181PTPN14-FALSEMADE2SINE,Alu
chr1145500925TA0.00997NBPF20,NBPF10,LIX1L+FALSE
chr144072018CT0.00783PTPRF+FALSE
chr1205581853CT0.00171ELK4-FALSE
chr128661653AG9.75782E-05MED18+TRUEAluSgSINE,Alu
chr42070260GA0.00724NAT8L+FALSE(TG)nSINE,Alu
chr1152552285CA0.00400LCE3D-FALSE
chr193803522TC0.00163CCDC18-AS1-TRUEAluJrSINE,Alu
chr5170832637CT0.00071NPM1+FALSE
chr2203744550TC0.00037.FALSEAluSx1SINE,Alu
chr121611791CG0.00971LINC00942+FALSE
chr211323078CT0.00539ROCK2-FALSE
chr124128467CT0.00086HMGCL-FALSE
chr299812464AG0.00998MRPL30+TRUEAluSxSINE,Alu
chr2105881071CA0.00851TGFBRAP1-FALSE
chr1249139806GA0.00983ZNF672+FALSE
chr353263333GA0.00329TKT-FALSE
chr237327702TC0.00119.FALSE
chr167874849TC7.36358E-05SERBP1-TRUEAluSxSINE,Alu
chr631324202TA0.00300.FALSE
chr117326540GA0.00120ATP13A2-FALSE
chr1120164252GA0.00139ZNF697-FALSE
chr8144940798TC0.00255EPPK1-FALSE
chr116927379TA0.00864NBPF1-FALSE
chr1081114959CT0.00048PPIF+FALSEMSTASINE,Alu
chr457326879AG0.00198PAICS+TRUEAluSx1SINE,Alu
chr1121133392TC0.00651SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSEL1MB4SINE,Alu
chr185785107TC4.02203E-05DDAH1-FALSE
chr540832550CT7.98859E-06RPL37-FALSE
chr131905886CA0.00702SERINC2+FALSE
chr5134260212CT0.00264PCBD2+FALSE
chr1120611964GC0.00130NOTCH2-FALSE
chr1174551853AC0.00079RNF169+FALSE
chr146828734TC0.00604NSUN4+FALSE
chr1452906081TG0.00602TXNDC16-FALSE
chr11668089GT0.00801SLC35E2-FALSEAluSzSINE,Alu
chr1119693495AG0.00996LOC101929147+TRUEAluSxSINE,Alu
chr5151041886TG0.00269SPARC-FALSE
chr12133298917AG0.00612PGAM5+TRUEAluSgSINE,Alu
chr1741144581AC0.00806RUNDC1+FALSEAluSxSINE,Alu
chr2174090336AC0.00331ZAK,MLK7-AS1+,-FALSEAluSxSINE,Alu
chr3197612370AG0.00157.FALSEAluSpSINE,Alu
chr1161931167AG0.00251ATF6+FALSE
chr4170037423GT0.00802SH3RF1-FALSE
chr1145369556AG0.00086NBPF20,NBPF10+TRUEL1MC4SINE,Alu
chr111722688GA0.00076FBXO44+FALSE
chr110459165GA2.83145E-06PGD+FALSE
chr1298942679AG2.08991E-07TMPO+FALSEAluScSINE,Alu
chr110517653TC1.73226E-05.FALSEAluSx1SINE,Alu
chr232535568AG0.00192.FALSEMER8SINE,Alu
chr119585553AG0.00039MRTO4+TRUEAluSc8SINE,Alu
chr1945406536GT0.00518TOMM40+FALSE
chr227170943AC0.00684DPYSL5+FALSE(CA)nSINE,Alu
chr16684050GA2.21294E-05PHF13+FALSE
chr1204526554AG0.00194MDM4+TRUEAluSxSINE,Alu
chr6151678865TG0.00016AKAP12+FALSE(T)nSINE,Alu
chr12125511311AG0.00299THRIL-FALSEAluSx1SINE,Alu
chr3113528892AT8.78648E-05ATP6V1A+FALSEAluSpSINE,Alu
chr744918804TC0.00015PURB-TRUEAluSgSINE,Alu
chr3158547143GA0.00178MFSD1+FALSE
chr5150578574AG0.00447CCDC69-FALSE
chr128564252AG0.00118ATPIF1+FALSE
chr132793185CT0.00015HDAC1+FALSE
chr119953120GA0.00025MINOS1,MINOS1-NBL1+FALSE
chr121766776GC0.00343NBPF3+FALSE
chr11570921CT0.00411CDK11B-FALSE
chr2128952015AG0.00086UGGT1+TRUEAluSx1SINE,Alu
chr16583592TC0.00939NOL9-TRUEAluSqSINE,Alu
chr1212587320TC0.00023TMEM206-FALSE
chr123240263GA5.22984E-05EPHB2+FALSE
chrX77084007TC0.00141MAGT1-TRUEAluSzSINE,Alu
chr1162407518TC3.11115E-06GANAB-TRUEAluYSINE,Alu
chr7158525786GA0.00453ESYT2-FALSE
chr1121134204GT0.00557SRGAP2-AS1,SRGAP2B,SRGAP2C+,-FALSE(TTTCCT)nSINE,Alu
chr2232196570AG0.00765ARMC9+FALSE
chr1453242354TC3.85910E-06GNPNAT1-TRUEAluJoSINE,Alu
chr12123346990GT0.00055HIP1R+FALSE
chr1168215575GA0.00688ANKRD36BP1-FALSE
chr5177576461AT0.00659.FALSE
chr133086754TC0.00065.FALSEAluYSINE,Alu
chr2234386134AG0.00196USP40-FALSE
chr1114438951AG0.00017AP4B1-AS1,AP4B1+,-FALSE
chr11650797AG0.00276CDK11B,CDK11A-FALSE
chr7128293103AC0.00313LINC01000+FALSE
chr123636031TA0.00965HNRNPR-FALSE
chr145975584TC0.00327MMACHC+FALSEAluSx4SINE,Alu
chr897506373CG0.00579SDC2+FALSE(CCCCGAG)nSINE,Alu
chr11650807TC0.00104CDK11B,CDK11A-FALSE
chr7128144035AG0.00054.FALSEAluSq2SINE,Alu
chr128150601AT0.00558STX12+FALSE
chr2231032372AG0.00691.FALSEMLT1HSINE,Alu
chr1950412217CG0.00017IL4I1,NUP62-FALSE(GGT)nSINE,Alu
chr128261662AG0.00872SMPDL3B+FALSE
chr12121772025TC0.00562ANAPC5-TRUEAluJrSINE,Alu
chr76064011TA0.00246EIF2AK1-FALSE
chr111084103TA0.00146TARDBP+FALSE
chr1298943011AG1.18352E-07TMPO+TRUEAluSzSINE,Alu
chr128607959CA0.00230SESN2+FALSE
chr1116239368GA5.97604E-05VANGL1+FALSE
chr1590815787AG0.00055.FALSEFRAMSINE,Alu
chr136067749TC0.00748PSMB2-TRUEAluSzSINE,Alu
chr1145512024AG0.00836NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr652267967AC0.00424PAQR8+FALSE
chr2100019496AG0.00789REV1-FALSE
chr137949224CT7.78396E-10ZC3H12A+FALSE
chr1144594373CG0.00715NBPF20+FALSE
chr1419686228CT0.00106DUXAP10+FALSE
chr1115299504GT0.00067CSDE1-FALSE
chr136770605CT0.00041THRAP3+FALSE(T)nSINE,Alu
chr117345246AT0.00812SDHB-FALSE
chr2218571431AG0.00158PEX26+TRUEAluSzSINE,Alu
chr143916642TC0.00748SZT2+FALSEMIR3SINE,Alu
chr1253807911AT0.00355SP1+FALSE
chr3195460892AG0.00057.FALSEAluSgSINE,Alu
chr286364710TC0.00273PTCD3+FALSE
chr812880299AG1.70760E-05KIAA1456+TRUEAluJoSINE,Alu
chr63154871AC7.50591E-06TUBB2A-FALSE
chr285547772GC0.00871TGOLN2-FALSE
chr119542310TC0.00112LOC101927895,EMC1+,-FALSEAluSzSINE,Alu
chr1104097685CT0.00028RNPC3,AMY2B+FALSE
chr12106460001GA2.23324E-05NUAK1-FALSE
chr110518591AT0.00545.FALSE
chr2187544218TG0.00796ITGAV+FALSE
chr123636275GT0.00258HNRNPR-FALSE
chr8143744407TC0.00697JRK-TRUEAluJrSINE,Alu
chr11647902AT0.00191CDK11B,CDK11A-FALSE
chr189570148AG0.00084.FALSE
chr116918734GC0.00600NBPF1-FALSE
chr1582336939GA2.47536E-05MEX3B-FALSE
chr1145512944AG0.00171NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluSz6SINE,Alu
chr116889575TC0.00969NBPF1-TRUE
chr7148700783GA0.00557PDIA4-FALSE
chr1155838369GC0.00346SYT11+FALSE
chr124798089GA0.00815NIPAL3+FALSE
chr167451522AT0.00883MIER1+FALSE
chr153289852AG0.00894ZYG11B+TRUEFRAMSINE,Alu
chr1565442592TC8.95444E-05CLPX-TRUEAluSg4SINE,Alu
chr1117532372GT0.00678PTGFRN+FALSE
chr227838058CA0.00063ZNF512+FALSE
chr2206987109TC0.00280.FALSEAluSxSINE,Alu
chr126608021TA0.00069.FALSE
chr10114209888AG0.00386VTI1A+TRUEAluSx3SINE,Alu
chr1767538540TC0.00295.FALSE
chr3119212012AC0.00976POGLUT1+FALSE
chr116890607GA0.00869NBPF1-FALSE
chr1244571947CT0.00775ADSS-FALSE
chr230748507CT0.00103LCLAT1+FALSE

Differential Expression Gene Analysis