Dataset Overview
RBP
SMNDC1
Knock-Method
shRNA
RBP Family
SMN
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR995ZGJ
Platform
HiSeq
Pubmed ID
32252787
SMNDC1 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of SMNDC1
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
9.32
6.64
-0.47974
0.00017
0.00046
A1CF
29.34
31.47
0.12972
0.04656
0.07714
A2M
2342.22
2857.82
0.28115
2.03620E-06
7.79163E-06
AADAC
0.71
1.48
1.25817
5.80216E-05
0.00017
AAGAB
9.04
9.62
0.22710
0.01603
0.02999
AAK1
2.94
3.72
0.54361
1.13380E-05
3.83692E-05
AAMDC
19.44
9.3
-1.02055
2.11588E-09
1.17235E-08
AARS
40.96
45.01
0.14644
0.01896
0.03485
AASDH
5.11
3.96
-0.34054
0.00098
0.00238
AASS
9.93
6.17
-0.69161
4.07755E-12
3.05966E-11
Showing 1 to 10 of 8,070 entries
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Function Analysis of Target Genes of SMNDC1
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AAR2
34824803_34824959_34824386_34824425_34827742_34828547
0.00071
-0.103
DataSet_01_309
View details
AAR2
34824811_34824959_34824386_34824425_34827742_34828547
0.00472
-0.106
DataSet_01_309
View details
ABLIM1
116213137_116213242_116211382_116211430_116225456_116225586
0.00139
0.038
DataSet_01_309
View details
ACAD11
132297798_132297900_132297676_132297725_132298335_132298402
0.00231
-0.239
DataSet_01_309
View details
ACLY
40067478_40067659_40066474_40066537_40068672_40068795
0.00197
0.495
DataSet_01_309
View details
ADRM1
60879516_60879633_60878623_60878837_60881252_60881376
0.00149
0.046
DataSet_01_309
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ADRM1
60883423_60883526_60883038_60883234_60883710_60883918
0.00465
0.031
DataSet_01_309
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AFMID
76200908_76200981_76198783_76198832_76202026_76202131
0.00693
0.088
DataSet_01_309
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AFP
74313330_74313393_74309063_74309161_74315051_74315184
0.00038
0.022
DataSet_01_309
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AFP
74310709_74310839_74309063_74309161_74315051_74315184
0.00434
0.011
DataSet_01_309
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Showing 1 to 10 of 369 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAA1
38169276_38169357_38170780_38170879_38168000_38168191
0.00481
0.08
DataSet_01_309
View details
ACAT1
108005868_108005969_108009624_108009768_108004947_108005043
0.00235
0.349
DataSet_01_309
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ACP1
272036_272150_275139_275201_271865_271939
0.00001
0.2
DataSet_01_309
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ACSL3
223752547_223752606_223765391_223765498_223725651_223725976
0.00158
0.088
DataSet_01_309
View details
ACSL3
223791734_223791907_223793579_223793654_223789173_223789313
0.00842
0.052
DataSet_01_309
View details
AFMID
76187050_76187141_76198575_76198684_76183397_76183514
0.00111
-0.085
DataSet_01_309
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AHSG
186336324_186336426_186337645_186337729_186334231_186334316
0.00000
-0.011
DataSet_01_309
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AHSG
186336079_186336280_186336324_186336426_186334975_186335139
0.00007
0.007
DataSet_01_309
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AHSG
186334975_186335139_186336324_186336426_186334231_186334316
0.00084
0.099
DataSet_01_309
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AHSG
186336358_186336426_186337645_186337729_186334975_186335139
0.00225
0.019
DataSet_01_309
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Showing 1 to 10 of 198 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACP1
271892_272065_271892_271939_272191_272305
0.00009
0.19
DataSet_01_309
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ADPRM
10608226_10608932_10608226_10608844_10609754_10609871
0.00218
-0.21
DataSet_01_309
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AL136419.6
24682614_24683357_24683199_24683357_24680885_24681035
0.00042
0.06
DataSet_01_309
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ALB
74279290_74279307_74279290_74279299_74280751_74280884
0.00000
-0.044
DataSet_01_309
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ARHGAP26
142586762_142587038_142586762_142586873_142593561_142593653
0.00337
-0.306
DataSet_01_309
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ATXN2L
28847253_28847806_28847253_28847443_28848048_28848558
0.00222
-0.189
DataSet_01_309
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BCL2L2-PABPN1
23793346_23793537_23793346_23793498_23794455_23794538
0.00072
0.11
DataSet_01_309
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BZW1
201676268_201676669_201676268_201676450_201677930_201678004
0.00622
-0.186
DataSet_01_309
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CFB
31915732_31915971_31915732_31915858_31916150_31916289
0.00037
0.04
DataSet_01_309
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CHPT1
102120071_102120275_102120071_102120182_102122678_102122852
0.00875
0.153
DataSet_01_309
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Showing 1 to 10 of 34 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAD10
112186814_112187007_112186976_112187007_112186120_112186279
0.00853
-0.192
DataSet_01_309
View details
ADSSL1
105205991_105206153_105206103_105206153_105205664_105205715
0.00949
0.457
DataSet_01_309
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ALAD
116154398_116154615_116154398_116154449_116155726_116155914
0.00894
-0.109
DataSet_01_309
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ANKHD1
139818045_139818202_139818087_139818202_139815688_139815842
0.00248
0.27
DataSet_01_309
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AP2A2
985431_985582_985434_985582_984644_984753
0.00547
0.136
DataSet_01_309
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APOA2
161192707_161192840_161192707_161192784_161193139_161193215
0.00004
-0.015
DataSet_01_309
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APOA2
161192707_161193056_161192707_161192784_161193139_161193215
0.00009
-0.036
DataSet_01_309
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APOA2
161193139_161193247_161193139_161193215_161193384_161193421
0.00059
-0.027
DataSet_01_309
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APOB
21265232_21265410_21265232_21265348_21266384_21266423
0.00535
0.017
DataSet_01_309
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ARFGAP1
61917717_61917794_61917723_61917794_61917005_61917065
0.00322
0.042
DataSet_01_309
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACTR1B
98274889_98275466_98274889_98275106_98275341_98275466
0.00003
0.236
DataSet_01_309
View details
AMBRA1
46563494_46564948_46563494_46564531_46564801_46564948
0.00027
-0.281
DataSet_01_309
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AP1G2
24031712_24032847_24031712_24031802_24032588_24032847
0.00011
0.182
DataSet_01_309
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ARL16
79649063_79650624_79649063_79650156_79650565_79650624
0.00875
-0.076
DataSet_01_309
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ASPSCR1
79974675_79974989_79974675_79974745_79974816_79974989
0.00142
0.053
DataSet_01_309
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ATXN2L
28847253_28848558_28847253_28847806_28848048_28848558
0.00362
0.078
DataSet_01_309
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ATXN2L
28847253_28848558_28847253_28847443_28848048_28848558
0.00582
-0.098
DataSet_01_309
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BRD2
32944338_32945347_32944338_32944713_32945218_32945347
0.00156
0.058
DataSet_01_309
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BTBD3
11898425_11899249_11898425_11898659_11898981_11899249
0.00783
-0.291
DataSet_01_309
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C17orf76-AS1
16342894_16343567_16342894_16343017_16343498_16343567
0.00000
-0.048
DataSet_01_309
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
9428685
T
G
0.00416
SPSB1
+
FALSE
chr1
61922059
C
A
0.00132
NFIA
+
FALSE
(A)n
SINE,Alu
chr1
179012947
C
G
0.00501
FAM20B
+
FALSE
chr1
138980
G
T
0.00608
LOC729737
-
FALSE
chr1
19586501
A
G
0.00019
MRTO4
+
TRUE
AluSz
SINE,Alu
chr1
94032944
C
T
0.00147
BCAR3
-
FALSE
chr1
16945227
G
T
0.00139
CROCCP2
-
FALSE
chr1
204096630
T
C
0.00471
SOX13
+
FALSE
chr1
570178
G
A
0.00787
.
FALSE
chr1
109746825
A
G
0.00427
KIAA1324
+
TRUE
AluJb
SINE,Alu
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression