Dataset Overview
RBP
KHSRP
Knock-Method
shRNA
RBP Family
KH_1
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR850CKU
Platform
HiSeq
Pubmed ID
32252787
KHSRP - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of KHSRP
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
40.38
30.37
-0.47249
0.00075
0.00275
A2M
2827.98
2123.58
-0.46348
1.39610E-06
1.04308E-05
AAAS
21.26
18.62
-0.35805
0.00243
0.00760
AACS
17.52
13.4
-0.45345
6.55237E-06
4.15619E-05
AADAT
2.45
4.4
0.66711
0.00028
0.00117
AAK1
1.2
1.94
1.07652
1.85363E-07
1.67096E-06
AAMP
124.44
112.7
-0.24041
0.01090
0.02734
AAR2
22.2
19.67
-0.25870
0.01109
0.02772
AARS
51.81
37.24
-0.59371
1.74295E-10
2.98940E-09
AARS2
3.9
5.09
0.26914
0.03997
0.08061
Showing 1 to 10 of 6,739 entries
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Function Analysis of Target Genes of KHSRP
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AARS
70288293_70288386_70287821_70287941_70288523_70288637
0.00573
0.035
DataSet_01_310
View details
AARS
70298860_70299005_70294946_70295060_70299440_70299565
0.00777
-0.522
DataSet_01_310
View details
ABCC6
16249648_16249711_16248729_16248888_16251519_16251666
0.00132
0.587
DataSet_01_310
View details
ABCC6P1
18585641_18585757_18584198_18584382_18586082_18586208
0.00178
0.22
DataSet_01_310
View details
ABHD3
19263880_19263926_19244078_19244191_19282276_19282459
0.00944
-0.13
DataSet_01_310
View details
AC003002.6
57902089_57902213_57901251_57901482_57905555_57905591
0.00025
-0.368
DataSet_01_310
View details
AC007390.5
37425636_37425815_37423647_37423663_37426846_37426962
0.00170
0.067
DataSet_01_310
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AC093642.5
243058333_243058383_243056789_243056892_243061115_243061208
0.01000
0.22
DataSet_01_310
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ACSF2
48541178_48541270_48540876_48540913_48541578_48541655
0.00540
-0.111
DataSet_01_310
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ACSL4
108887273_108887415_108872578_108872808_108902582_108902740
0.00058
-0.5
DataSet_01_310
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Showing 1 to 10 of 567 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABAT
8829555_8829666_8839857_8839955_8768421_8768568
0.00533
-0.12
DataSet_01_310
View details
ACIN1
23559730_23559842_23562687_23562753_23550956_23551045
0.00337
0.16
DataSet_01_310
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ACLY
40068672_40068795_40069967_40070149_40066474_40066537
0.00674
0.123
DataSet_01_310
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ACP1
272036_272150_276979_277085_271865_271939
0.00647
-0.088
DataSet_01_310
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ACTN4
39200896_39200982_39201915_39202001_39200034_39200116
0.00381
-0.043
DataSet_01_310
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AFMID
76187050_76187141_76198579_76198691_76183442_76183514
0.00871
-0.498
DataSet_01_310
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AFP
74306318_74306530_74318117_74318341_74303890_74304023
0.00096
-0.082
DataSet_01_310
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AHSG
186336079_186336280_186337645_186337863_186334975_186335139
0.00013
-0.152
DataSet_01_310
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AHSG
186336079_186336280_186336324_186336426_186334975_186335139
0.00032
-0.01
DataSet_01_310
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AHSG
186336351_186336426_186337645_186337702_186334975_186335139
0.00140
-0.064
DataSet_01_310
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Showing 1 to 10 of 183 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACSS2
33508751_33508969_33508751_33508942_33509132_33509276
0.00030
0.099
DataSet_01_310
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AFMID
76198652_76198691_76198652_76198684_76198783_76198832
0.00079
0.225
DataSet_01_310
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ALKBH6
36504211_36504324_36504245_36504324_36503922_36503991
0.00843
0.156
DataSet_01_310
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AP1G2
24035024_24035369_24035272_24035369_24034814_24034910
0.00671
-0.138
DataSet_01_310
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AP3D1
2130392_2130536_2130406_2130536_2129316_2129456
0.00617
0.104
DataSet_01_310
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APEX1
20923736_20923932_20923736_20923862_20924072_20924260
0.00026
0.038
DataSet_01_310
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ATP13A1
19763359_19763529_19763403_19763529_19762497_19762606
0.00170
0.179
DataSet_01_310
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AUP1
74755877_74756409_74756258_74756409_74755543_74755616
0.00054
-0.155
DataSet_01_310
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BPTF
65941524_65942441_65941524_65942012_65943841_65943924
0.00571
-0.147
DataSet_01_310
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CASD1
94164620_94164835_94164620_94164700_94166783_94167206
0.00600
-0.2
DataSet_01_310
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Showing 1 to 10 of 78 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A2M
9256834_9257010_9256834_9256996_9258831_9258892
0.00953
0.499
DataSet_01_310
View details
ABLIM1
116207638_116207785_116207638_116207779_116211382_116211430
0.00000
-0.272
DataSet_01_310
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ABLIM1
116207638_116207819_116207638_116207779_116211382_116211430
0.00495
-0.164
DataSet_01_310
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ACADVL
7127798_7127871_7127802_7127871_7127639_7127712
0.00332
-0.172
DataSet_01_310
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ADSSL1
105206086_105206153_105206103_105206153_105205664_105205715
0.00180
0.123
DataSet_01_310
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AGFG1
228418419_228418511_228418425_228418511_228416674_228416833
0.00074
-0.146
DataSet_01_310
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AHCY
32880163_32880359_32880163_32880313_32881886_32881962
0.00031
0.027
DataSet_01_310
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AMT
49459536_49459704_49459536_49459690_49459793_49459891
0.00074
0.214
DataSet_01_310
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ANAPC5
121756079_121756227_121756079_121756207_121756303_121756411
0.00606
-0.071
DataSet_01_310
View details
AP1G2
24031170_24031411_24031170_24031275_24031496_24031624
0.00312
-0.08
DataSet_01_310
View details
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AHSA2
61412636_61413632_61412636_61412753_61413580_61413632
0.00000
0.236
DataSet_01_310
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AKT2
40742163_40743998_40742163_40742292_40743875_40743998
0.00420
0.068
DataSet_01_310
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AMT
49454210_49455151_49454210_49454800_49455047_49455151
0.00233
-0.169
DataSet_01_310
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ANAPC5
121764898_121766300_121764898_121765034_121766118_121766300
0.00001
0.127
DataSet_01_310
View details
ANAPC5
121756079_121756411_121756079_121756227_121756303_121756411
0.00012
0.081
DataSet_01_310
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AP1G2
24035024_24035369_24035024_24035101_24035272_24035369
0.00119
0.129
DataSet_01_310
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APEX1
20923736_20924260_20923736_20923862_20924072_20924260
0.00068
0.057
DataSet_01_310
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ARF5
127229538_127230191_127229538_127229648_127230119_127230191
0.00887
0.015
DataSet_01_310
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ARHGEF1
42396095_42396444_42396095_42396194_42396401_42396444
0.00627
0.185
DataSet_01_310
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ARL6IP4
123466503_123467085_123466503_123466621_123467015_123467085
0.00001
0.027
DataSet_01_310
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
109192040
T
C
6.39517E-05
HENMT1
-
TRUE
AluJr
SINE,Alu
chr1
144852203
T
G
0.00518
NBPF20,PDE4DIP
+,-
FALSE
chr1
36068295
T
C
2.11660E-05
PSMB2
-
TRUE
AluSc
SINE,Alu
chr1
145689028
A
G
9.93195E-07
NBPF20,NBPF10
+
TRUE
AluSc8
SINE,Alu
chr1
245017464
T
A
0.00624
HNRNPU,SNORA100
-
FALSE
chr1
12024235
C
T
0.00395
PLOD1
+
FALSE
chr1
79126336
C
G
1.94494E-06
IFI44
+
FALSE
chr1
35658211
G
T
1.28982E-07
SFPQ
-
FALSE
chr1
12073252
A
G
0.00990
MFN2
+
FALSE
chr1
45976723
T
C
0.00340
MMACHC,PRDX1
+,-
FALSE
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression