Dataset Overview
RBP
PUM1
Knock-Method
shRNA
RBP Family
PUF
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR945XKW
Platform
HiSeq
Pubmed ID
32252787
PUM1 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of PUM1
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1BG
15.89
6.64
-1.13916
4.41193E-13
2.98385E-12
A1CF
30.66
16.83
-0.62690
8.73610E-18
8.65274E-17
A2M
2149.68
1531.07
-0.46130
1.56661E-09
7.41551E-09
AACS
15.28
12.66
-0.34861
3.69492E-05
0.00010
AADAC
0.57
2.55
1.81505
5.97215E-12
3.67186E-11
AADAT
4.81
8.45
0.56104
2.23639E-06
7.35630E-06
AAED1
6.5
5.28
-0.39831
0.00023
0.00056
AAGAB
8.9
18.51
0.89227
3.02347E-22
4.14829E-21
AAK1
2.42
4.63
0.96936
2.20837E-16
1.97017E-15
AAMDC
23.01
17.4
-0.45737
0.00058
0.00133
Showing 1 to 10 of 8,708 entries
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Function Analysis of Target Genes of PUM1
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52623792_52623840_52619601_52619745_52645340_52645435
0.00047
0.083
DataSet_01_314
View details
ABCC2
101576820_101576968_101572774_101572901_101577064_101577241
0.00018
-0.161
DataSet_01_314
View details
ABCC2
101579184_101579299_101578845_101579026_101590063_101590190
0.00076
-0.039
DataSet_01_314
View details
ABCC2
101579193_101579299_101578845_101579026_101590063_101590190
0.00131
-0.033
DataSet_01_314
View details
ABCC2
101576820_101576911_101572774_101572901_101577064_101577156
0.00477
-0.112
DataSet_01_314
View details
ABCC6P1
18585641_18585757_18584198_18584382_18586082_18586208
0.00168
0.239
DataSet_01_314
View details
ABHD12
25300834_25300954_25297683_25297714_25303960_25304066
0.00634
-0.079
DataSet_01_314
View details
ABI1
27044583_27044670_27040526_27040712_27047990_27048167
0.00000
-0.286
DataSet_01_314
View details
ABI1
27044583_27044670_27040526_27040712_27054146_27054247
0.00044
-0.537
DataSet_01_314
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AC005592.2
141770562_141770616_141732790_141733148_141843534_141843624
0.00586
0.58
DataSet_01_314
View details
Showing 1 to 10 of 489 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
A1CF
52610424_52610567_52619601_52619745_52603747_52603882
0.00102
-0.145
DataSet_01_314
View details
ABCF1
30548182_30548296_30550170_30550284_30547707_30547782
0.00982
-0.12
DataSet_01_314
View details
ABI1
27044583_27044670_27047990_27048167_27040526_27040712
0.00000
0.251
DataSet_01_314
View details
ABI1
27044583_27044670_27047990_27048164_27040526_27040712
0.00000
0.298
DataSet_01_314
View details
ABI2
204244930_204245107_204255768_204255866_204231599_204231767
0.00086
-0.307
DataSet_01_314
View details
ABLIM1
116207638_116207779_116211382_116211430_116205070_116205162
0.00004
-0.194
DataSet_01_314
View details
AC002116.8
36503902_36503991_36504245_36504324_36502305_36502366
0.00290
-0.084
DataSet_01_314
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ACADVL
7126451_7126556_7126962_7127049_7126078_7126184
0.00035
-0.095
DataSet_01_314
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ACTN4
39200896_39200982_39201915_39202001_39200034_39200116
0.00039
0.033
DataSet_01_314
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AHSG
186336079_186336280_186336351_186336426_186334975_186335139
0.00000
-0.332
DataSet_01_314
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Showing 1 to 10 of 175 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AHSA2
61411846_61412059_61411846_61411935_61412636_61412753
0.00517
0.041
DataSet_01_314
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AKAP8L
15509440_15510221_15510112_15510221_15508524_15508666
0.00485
0.109
DataSet_01_314
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AKR1A1
46032540_46032758_46032540_46032692_46033653_46033849
0.00101
-0.032
DataSet_01_314
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AKR1C2
5041391_5042858_5042741_5042858_5040816_5040939
0.00505
0.052
DataSet_01_314
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AP2M1
183900544_183900743_183900544_183900656_183901269_183901853
0.00040
-0.038
DataSet_01_314
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APOM
31624248_31624410_31624248_31624403_31625001_31625075
0.00151
-0.026
DataSet_01_314
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ATG4B
242590424_242590750_242590424_242590526_242592926_242593025
0.00107
-0.115
DataSet_01_314
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AUP1
74755877_74756409_74756258_74756409_74755379_74755616
0.00022
-0.161
DataSet_01_314
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C19orf80
11350294_11350610_11350294_11350464_11350810_11350972
0.00950
-0.041
DataSet_01_314
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CFB
31912561_31912806_31912561_31912630_31912954_31912963
0.00004
-0.09
DataSet_01_314
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Showing 1 to 10 of 41 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACIN1
23537689_23537928_23537689_23537880_23538684_23538826
0.00078
0.143
DataSet_01_314
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ACSL4
108926364_108926781_108926364_108926604_108934231_108934360
0.00023
-0.534
DataSet_01_314
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ACSL4
108926364_108926781_108926364_108926601_108934231_108934360
0.00500
-0.172
DataSet_01_314
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APOL1
36650943_36651045_36650982_36651045_36649178_36649265
0.00023
0.034
DataSet_01_314
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APRT
88875876_88876248_88875876_88876114_88876477_88876556
0.00251
0.096
DataSet_01_314
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ASGR2
7005408_7005515_7005408_7005472_7010318_7010470
0.00206
-0.014
DataSet_01_314
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AUP1
74754338_74754523_74754338_74754436_74754597_74754717
0.00774
-0.494
DataSet_01_314
View details
AUP1
74754374_74754490_74754374_74754436_74754597_74754717
0.00814
-0.021
DataSet_01_314
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AURKB
8111055_8111219_8111055_8111158_8113847_8113899
0.00042
-0.249
DataSet_01_314
View details
BAG6
31608161_31608334_31608161_31608305_31608421_31608481
0.00307
0.089
DataSet_01_314
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Showing 1 to 10 of 63 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACADVL
7125985_7126556_7125985_7126184_7126451_7126556
0.00064
0.118
DataSet_01_314
View details
ANAPC5
121783641_121784808_121783641_121783834_121784698_121784808
0.00158
0.102
DataSet_01_314
View details
ATF4
39916568_39917676_39916568_39916756_39917358_39917676
0.00000
-0.056
DataSet_01_314
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ATG4B
242590424_242590750_242590424_242590526_242590678_242590750
0.00000
0.028
DataSet_01_314
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BCL2L1
30309457_30310400_30309457_30310133_30310219_30310400
0.00889
-0.103
DataSet_01_314
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CARS
3047905_3050314_3047905_3048027_3050225_3050314
0.00726
-0.047
DataSet_01_314
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CLK1
201724402_201726189_201724402_201724469_201725960_201726189
0.00589
0.192
DataSet_01_314
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COL7A1
48608675_48609478_48608675_48608711_48609433_48609478
0.00575
0.297
DataSet_01_314
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CPNE1
34213965_34214725_34213965_34214303_34214488_34214725
0.00007
-0.025
DataSet_01_314
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CSF3R
36938117_36939223_36938117_36938287_36939035_36939223
0.00844
-0.087
DataSet_01_314
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
9163393
T
C
0.00327
.
FALSE
AluSp
SINE,Alu
chr1
10519982
T
C
0.00417
.
FALSE
AluJr
SINE,Alu
chr1
117644949
C
G
0.00440
TTF2
+
FALSE
chr1
53288862
A
G
0.00799
ZYG11B
+
TRUE
AluJo
SINE,Alu
chr1
1252510
T
C
1.62601E-05
CPSF3L
-
TRUE
AluSp
SINE,Alu
chr1
54571374
A
G
0.00916
TCEANC2
+
TRUE
AluSc
SINE,Alu
chr1
10520649
T
C
0.00629
DFFA
-
TRUE
AluSc8
SINE,Alu
chr1
36067821
T
C
8.78017E-05
PSMB2
-
TRUE
AluSz
SINE,Alu
chr1
206578650
G
C
0.00159
SRGAP2
+
FALSE
chr1
148561089
T
C
0.00011
NBPF15
+
FALSE
Showing 1 to 10 of 276 entries
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression