Dataset Overview
RBPUBTF
Knock-MethodCRISPRi
RBP FamilyNon-canonical_RBP
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR608ORR
PlatformHiSeq
Pubmed ID32252787

UBTF - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of UBTF
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of UBTF


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1145512024AG0.00084NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1567783TC0.00427MIR6723-FALSE
chr1049609751AG0.00979MAPK8+FALSE
chr299772827AG0.00108LIPT1+TRUEAluSx1SINE,Alu
chr110003320GA0.00168LZIC,NMNAT1+,-FALSE
chr1200375835GT0.00063ZNF281-FALSE(T)nSINE,Alu
chr111783105AG4.69824E-05.FALSEAluSxSINE,Alu
chr175288079AC0.00085RABEP1+FALSE
chr1749042216TC0.00746SPAG9-TRUEAluJbSINE,Alu
chr133148736AG0.00525SYNC,RBBP4+,-FALSEAluScSINE,Alu
chr2196999052CG0.00358STK17B-FALSEMER1BSINE,Alu
chr697592894AC0.00654MMS22L-FALSE
chr110521103TC0.00788DFFA-TRUEAluYSINE,Alu
chr135650022CA0.00762SFPQ-FALSE
chr76063466TA0.00153EIF2AK1-FALSE
chr540829980TC0.00752.FALSEAluSpSINE,Alu
chr189477559CT0.00044GBP3-FALSE
chr555235967AG0.00639IL6ST-FALSE(AT)nSINE,Alu
chr9131457039CT0.00148SET+FALSE
chr147184569GC0.00027EFCAB14-FALSE
chr125663918GA0.00951RSRP1-FALSE
chr534906547TC0.00051RAD1-TRUEAluJoSINE,Alu
chr285772405TA0.00016GGCX-FALSE
chr2176792488GT0.00195LNPK-FALSE
chr19161203TC3.69156E-05.FALSEAluSxSINE,Alu
chr1936575645GA0.00590WDR62+FALSE
chr1911945631AG0.00091ZNF440+TRUEAluSpSINE,Alu
chr314526653GT0.00936SLC6A6+FALSE
chr1150619971GA0.00126GOLPH3L-FALSEAluJoSINE,Alu
chr2178129405CT0.00295NFE2L2-FALSE(CGG)nSINE,Alu
chr16282420TC0.00779ICMT-TRUEAluSzSINE,Alu
chr167874696TC0.00245SERBP1-TRUEAluSx3SINE,Alu
chr236704035CA0.00012CRIM1+FALSE
chr349460407CT0.00080NICN1-FALSEL2cSINE,Alu
chr1610623706TC0.00064EMP2-TRUEAluSpSINE,Alu
chr7117832138GA0.00885LSM8+FALSE
chr111782984AG0.00107.FALSEAluSxSINE,Alu
chr1145290818CG0.00931NBPF20+FALSE
chr775145495GA5.48132E-07PMS2P3-FALSE
chr1534634033AG0.00939NOP10-FALSE
chr12133298254AG0.00849PGAM5+TRUEAluSpSINE,Alu
chr1916661541TC0.00120SLC35E1-TRUEAluSzSINE,Alu
chr5175934037CA0.00182FAF2+FALSEA-richSINE,Alu
chr237331578TC0.00675.FALSEAluJbSINE,Alu
chr5149013587GA0.00102ARHGEF37+FALSEL2dSINE,Alu
chr642856039AG1.34846E-05RPL7L1+TRUEAluSzSINE,Alu
chr1179012947CG0.00501FAM20B+FALSE
chr153291382AG0.00132ZYG11B+TRUEAluJrSINE,Alu
chr1145512074AG0.00014NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr1162497663GA0.00365UHMK1+FALSE
chr128835934AG0.00069SNHG3,RCC1+TRUEAluSx4SINE,Alu
chr9131071533TC0.00168TRUB2-TRUEFAMSINE,Alu
chr19328086GA0.00017H6PD+FALSEAluJrSINE,Alu
chr239009427AG1.04745E-05.FALSEAluSx3SINE,Alu
chr110517538TC0.00840.FALSEAluSx1SINE,Alu
chr1160967890TC0.00871F11R-TRUEAluSpSINE,Alu
chr237330172TG0.00972.FALSE
chr1151092839AG0.00135GABPB2+TRUEAluSpSINE,Alu
chr1203821865CT0.00222ZC3H11A+FALSE
chr1118409491AT0.00471GDAP2-FALSE(A)nSINE,Alu
chr12124146597AG0.00121GTF2H3+TRUEAluSq2SINE,Alu
chr4165998642TC0.00036TMEM192-TRUEAluSgSINE,Alu
chr170718276GT0.00836.FALSE
chr1774561213AG0.00241SNHG16+FALSE
chr330047174AT0.00556RBMS3+FALSE
chr413604418GC2.95746E-07BOD1L1-FALSE
chr1167782827GA0.00163ALDH3B1+FALSE
chr6160101733TC0.00784SOD2-TRUEAluSzSINE,Alu
chr114150032CT0.00163PRDM2+FALSE
chr1157092836GA0.00383.FALSE
chr116958833TA0.00765.FALSE
chr16283296TC0.00225ICMT-TRUEAluSx3SINE,Alu
chr2109401284GC0.00059RANBP2+FALSE
chrX119572534CA0.00387LAMP2-FALSE
chr237331221TC1.68149E-05.FALSEAluSx1SINE,Alu
chr119447819TC0.00337UBR4-FALSE
chr314186757CG0.00864XPC-FALSE
chr495586725TA0.00743PDLIM5+FALSE
chr116890421GA0.00024NBPF1-FALSE
chr2176789478TC0.00219LNPK-TRUEMSTB1SINE,Alu
chr13546269CA0.00260TPRG1L+FALSEAluSzSINE,Alu
chr138327542TC0.00068INPP5B-TRUEAluSx3SINE,Alu
chr11594197CT0.00097CDK11B,SLC35E2B-FALSE
chr830536143TC0.00883GSR-TRUEAluJrSINE,Alu
chr116890639CT8.47214E-05NBPF1-FALSE
chr1245008386GC0.00041.FALSEMER2SINE,Alu
chr117998CT0.00995WASH7P-FALSE
chr1117532790CT0.00981PTGFRN+FALSE
chr140537922AG0.00686CAP1+FALSE(A)nSINE,Alu
chr1013687171TC0.00033FRMD4A-FALSE
chr1114438951AG0.00017AP4B1-AS1,AP4B1+,-FALSE
chr568936027GA0.00868.FALSE
chr1154323598TA0.00198ATP8B2+FALSE(TA)nSINE,Alu
chr127202982TC0.00850.FALSEAluSq2SINE,Alu
chr197084638AG0.00508ZNF557+TRUEAluJbSINE,Alu
chr5180682611CA9.20591E-05CTC-338M12.4+FALSE
chr558267557CT0.00420PDE4D-FALSE
chr338566722TC0.00426EXOG+FALSEMIRbSINE,Alu
chr35222483TG1.83612E-05ARL8B+FALSE
chr1179326296AG0.00171SOAT1+TRUE
chr154354935GC0.00831YIPF1-FALSE
chr1150548881GA9.52924E-05MCL1-FALSE
chr2102484482GA0.00213MAP4K4+FALSE
chr19643873AG0.00064.FALSEAluYSINE,Alu
chr11683565GA0.00269NADK-FALSE
chr136067817TC7.91657E-05PSMB2-TRUEAluSzSINE,Alu
chr1205687358TC0.00432NUCKS1-FALSE(T)nSINE,Alu
chr1109475572AG0.00170GPSM2,CLCC1+,-FALSEAluJoSINE,Alu
chrX133930368TG0.00126FAM122B-FALSEG-richSINE,Alu
chr1179044110AG5.39593E-06FAM20B+TRUEAluSxSINE,Alu
chr722984967AG0.00108FAM126A-FALSE
chr192976590GA0.00629EVI5-FALSE
chr2183622547TG0.00346DNAJC10+FALSE
chr1165877671TC0.00376UCK2+FALSE(T)nSINE,Alu
chr110519148TC0.00214.FALSEAluSx3SINE,Alu
chr1541590972AG2.40282E-05OIP5-AS1+TRUEAluSx1SINE,Alu
chr9115446659TC0.00410INIP-TRUEAluJrSINE,Alu
chr147843356AT0.00556CMPK1+FALSE
chr1202821382TC0.00983.FALSEAluJrSINE,Alu
chr3183890097GA1.43668E-06DVL3+FALSE
chr135817022TA0.00072ZMYM4+FALSE
chr1109746728AG0.00171KIAA1324+TRUEAluJbSINE,Alu
chr128826023AG0.00143PHACTR4+FALSEAluJbSINE,Alu
chr1154321623GA0.00782ATP8B2+FALSE
chr1201846630CA0.00212IPO9+FALSE(CA)nSINE,Alu
chr613788200TC0.00879MCUR1-TRUEAluSxSINE,Alu
chr1205129319GA0.00177DSTYK-FALSE
chr299812398AG0.00019MRPL30+TRUEAluSxSINE,Alu
chr1474526975TC0.00024BBOF1,ALDH6A1+,-FALSEAluJoSINE,Alu
chr246612340GT0.00094EPAS1+FALSE
chr163207362AT1.09222E-05.FALSE
chr285548639AG0.00687TGOLN2-FALSE
chr185278156CT0.00663.FALSEAluSz6SINE,Alu
chr1350102992TC0.00956SETDB2-PHF11,PHF11+FALSEL2aSINE,Alu
chr1183105534TC0.00424LAMC1+FALSE
chr193599279GA0.00849MTF2+FALSE
chr1331033317CT0.00254HMGB1-FALSE
chr29770610AG0.00466YWHAQ-FALSE
chr8144827206AT0.00196FAM83H-AS1+FALSEERVL-B4-intSINE,Alu
chr1223967953CT0.00341TP53BP2-FALSE
chr1144604425CT0.00299NBPF20+FALSE
chr119543465TC0.00117LOC101927895,EMC1+,-FALSEAluJbSINE,Alu
chr871550832TC0.00725LACTB2-AS1,LACTB2+,-FALSE
chr124296869GT0.00505.FALSEAluSgSINE,Alu
chr1919791276AG0.00069ZNF101+TRUEAluSq2SINE,Alu
chr811700737TC0.00126CTSB-TRUEAluSgSINE,Alu
chr1115275398TG0.00474CSDE1-FALSE
chr1143135166GT0.00325LOC102723769-FALSE
chr231491690TC0.00335.FALSE
chrX3526658AT0.00152PRKX-FALSE(AC)nSINE,Alu
chr1174551853AC0.00079RNF169+FALSE
chr6160526548CA0.00086IGF2R+FALSE
chr237331019TC0.00597.FALSEAluSx1SINE,Alu
chr128662253AG0.00117MED18+TRUEAluSq2SINE,Alu
chr126158906CA0.00362MTFR1L,AUNIP+,-FALSE
chr19664845CT1.14015E-08TMEM201+FALSE
chr7158590740AT0.00211ESYT2-FALSE
chr3181430146CA0.00256SOX2-OT,SOX2+FALSE
chr1220154768CT0.00067RNU5F-1,EPRS+,-FALSE
chr140982042GA0.00330EXO5+FALSEAluSxSINE,Alu
chr121602602AG8.31525E-05ERC1+FALSEAluSxSINE,Alu
chr5156905300AC0.00870ADAM19-FALSEMER92BSINE,Alu
chr16582868TC0.00368NOL9-TRUEAluSgSINE,Alu
chr1667715890TC9.92672E-05GFOD2-TRUEAluJrSINE,Alu
chr12125511242AG0.00015THRIL-FALSEAluSx1SINE,Alu
chr3197682723TA0.00686IQCG-FALSE
chr116945227GT0.00353CROCCP2-FALSE
chr126608014CA1.07737E-06.FALSE
chr1954971229TC0.00202LENG8+FALSE
chr124296856TG0.00564.FALSEAluSgSINE,Alu
chr138182164TA3.45866E-07EPHA10-FALSE
chr119428086GT0.00449UBR4-FALSE
chr5137087812AC0.00607HNRNPA0-FALSE
chr2128951904AG0.00444UGGT1+TRUEAluSx1SINE,Alu
chr144463185TG0.00427SLC6A9-FALSE
chr187213174TG0.00081SH3GLB1+FALSE
chr187572817CT0.00514HS2ST1+FALSE
chr5134061334AG0.00721SEC24A+FALSE
chr4152025795TA0.00516RPS3A+FALSE
chr2101622883TA0.00440RPL31+FALSE
chr3196670082AT0.00261NCBP2-AS2+FALSE
chr1725640011AG0.00228WSB1+TRUEAluSxSINE,Alu
chr110044366AG0.00958NMNAT1+TRUEAluSx1SINE,Alu
chr136067760TC0.00258PSMB2-TRUEAluSzSINE,Alu
chr110517513TC0.00982.FALSEAluSx1SINE,Alu
chr1205737659CT0.00024RAB29-FALSEAluSq2SINE,Alu
chr840011786CA0.00196C8orf4+FALSE
chr119810693GC0.00042CAPZB-FALSE
chr1183213770GC0.00734LAMC2+FALSE
chr116944809GC0.00072CROCCP2-FALSE
chr170904800GT0.00678CTH+FALSE
chr175288077GC0.00066RABEP1+FALSE
chr1207943385AG0.00558CD46+TRUEAluSx1SINE,Alu
chr1244572644GC0.00088ADSS-FALSE
chr190496700AG0.00486ZNF326+FALSE
chr1117945040GA0.00181MAN1A2+FALSE
chr119586501AG0.00055MRTO4+TRUEAluSzSINE,Alu
chr1109476363AG0.00172GPSM2,CLCC1+,-FALSE
chr413606576AT0.00737BOD1L1-FALSE
chr1742879245TC0.00834GJC1-TRUEAluSx1SINE,Alu
chr1345911310AT0.00685TPT1-FALSE
chr1911256725TC0.00096SPC24-TRUEAluJr4SINE,Alu
chr1326539AG0.00450.FALSE
chr128564195TC0.00113ATPIF1+FALSE
chr1220231276TC0.00937RNU5F-1,BPNT1+,-FALSEAluYSINE,Alu
chr1214524178TC0.00265PTPN14-TRUEAluSxSINE,Alu
chr1168218494AG0.00317.FALSEAluSzSINE,Alu
chr1015120278TC0.00018ACBD7-TRUEL1PA7SINE,Alu
chr133149443AG0.00013SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr272403405AC0.00227EXOC6B-FALSEGA-richSINE,Alu
chr146075663AG0.00543NASP+TRUEAluSx4SINE,Alu
chr3196670092CG0.00393NCBP2-AS2+FALSE
chr314986104TC0.00992FGD5-AS1-TRUEFLAM_CSINE,Alu
chr6153292178CT0.00783FBXO5-FALSE
chr2131906031CT0.00374PLEKHB2+FALSE
chr632147696GA6.22517E-06.FALSE
chr131532312CT0.00215PUM1-FALSE
chr1331033325CA0.00792HMGB1-FALSE
chr1161160459TC0.00270ADAMTS4-FALSE(CA)nSINE,Alu
chr229023121GT0.00077PPP1CB+FALSE
chr3100083460GA0.00041TOMM70-FALSEFAMSINE,Alu
chr136067677TC0.00522PSMB2-TRUEAluSzSINE,Alu
chr3196079280TC0.00614.FALSEAluSxSINE,Alu
chr1911560461AG0.00034PRKCSH+TRUEAluSxSINE,Alu
chr246852033AG0.00543CRIPT+FALSE
chr642849746AG0.00042RPL7L1+TRUEAluSzSINE,Alu
chr255462102AG0.00026RPS27A+FALSE
chr237328087TC0.00335.FALSE
chr1144599819CT0.00682NBPF20+FALSE
chr145975266AG0.00188MMACHC+TRUEAluSg7SINE,Alu
chr2113334178AT0.00654POLR1B+FALSEL1MA10SINE,Alu
chr541917696TA0.00045C5orf51+FALSE
chr237429733AG0.00381CEBPZOS,CEBPZ+,-FALSEAluSzSINE,Alu
chr1204521280AG0.00519MDM4+TRUEAluSpSINE,Alu
chr1160966434TC4.88498E-15F11R-TRUEAluSgSINE,Alu
chr124999468GT0.00075SRRM1+FALSE(T)nSINE,Alu
chr136067677TC1.65353E-05PSMB2-TRUEAluSzSINE,Alu
chr716640491GA0.00478ANKMY2-FALSE
chr110521172TC1.01590E-06DFFA-TRUEAluYSINE,Alu
chr1154323557CT0.00018ATP8B2+FALSE
chr1200558363TC1.35174E-05KIF14-FALSE
chr1169480680TC0.00252ORAOV1-FALSEAluSx1SINE,Alu
chr11345002AG0.00141.FALSEAluSgSINE,Alu
chr6126661502GT0.00873CENPW+FALSE
chr128836975AG0.00202SNHG3,RCC1+TRUEAluScSINE,Alu
chr1145689537AG0.00028NBPF20,NBPF10+TRUEAluSgSINE,Alu
chr1118167515CT3.85037E-05FAM46C+FALSE
chr2188330198CA0.00091TFPI-FALSEAluJbSINE,Alu
chr2218571477AG4.57932E-05PEX26+TRUEAluSzSINE,Alu
chr143391826GT0.00202SLC2A1-FALSE
chr119586532AG0.00769MRTO4+TRUEAluSzSINE,Alu
chr264119873AT0.00492VPS54-FALSE
chr1229652587TC0.00732ABCB10-FALSE
chr1205583610TC0.00501ELK4-FALSE
chr1117530188AG0.00199PTGFRN+FALSE
chr1153920564AG0.00747CRTC2-FALSE
chr8101269589AT0.00281RNF19A-FALSE
chr1772206017TA6.66319E-05RPL38+FALSE
chr1193058937CT0.00195TROVE2+FALSEAluScSINE,Alu
chr9131093971AG0.00033COQ4+TRUEAluJoSINE,Alu
chr111347150CA0.00380UBIAD1+FALSE
chr140213234AG0.00146PPIE+TRUEAluSx3SINE,Alu
chr4103809324AC0.00658CISD2,SLC9B1+,-FALSE
chr1958420152CA0.00322ZNF417-FALSE
chr146164493TC0.00822IPP-TRUEAluJbSINE,Alu
chr16583066TC0.00173NOL9-TRUEAluSx4SINE,Alu
chr154355105AG0.00398YIPF1-FALSEMIRbSINE,Alu
chr1144931392GA0.00683NBPF20,PDE4DIP+,-FALSE
chr1233518885TC0.00021MLK4+FALSE(TTTC)nSINE,Alu
chr12335871GA0.00298RER1+FALSE
chr1205111761AC0.00497DSTYK-FALSE
chr224224040AG0.00882.FALSEAluSpSINE,Alu
chr1145116142AT0.00570NBPF20,SEC22B+FALSE
chr111982580GA2.06927E-05KIAA2013-FALSE
chr1689623619AG0.00275SPG7+FALSE
chr7197322AG2.25895E-09FAM20C+FALSE
chr296573123CT0.00413ANKRD36C-FALSE
chr4128757345AG0.00040.FALSEAluYSINE,Alu
chr1110912873TC0.00116SLC16A4-FALSE
chr5130537223AG0.00044LYRM7+TRUEAluSpSINE,Alu
chr72394991CT9.93448E-08EIF3B+FALSE
chr11593023GC2.84325E-05CDK11B,SLC35E2B-FALSE
chr417803578TC0.00712DCAF16-TRUEAluYSINE,Alu
chr1963721TG0.00602WASH5P-FALSE
chr442088291CA0.00000SLC30A9+FALSE
chr1167973198AG0.00061DCAF6+FALSE
chr2128952015AG0.00908UGGT1+TRUEAluSx1SINE,Alu
chr1959095469AG5.44182E-05CENPBD1P1+TRUEAluJbSINE,Alu
chr1022824831CT0.00702PIP4K2A-FALSE
chr1120612194CG1.19417E-05NOTCH2-FALSE(CCG)nSINE,Alu
chr286252043TC0.00909POLR1A-TRUEAluSq2SINE,Alu
chr116929327CT0.00646NBPF1-FALSEERVL-E-intSINE,Alu
chr1146649884TA0.00338PDIA3P1+FALSE
chr1154438880TC0.00170IL6R+FALSE
chr848890293AG0.00125MCM4+TRUEAluJbSINE,Alu
chr7156763332AG0.00090NOM1+TRUEAluSxSINE,Alu
chr165147002CT6.62669E-07CACHD1+FALSE
chr1592715131AT0.00306SLCO3A1+FALSE
chr765844562TC0.00695LINC00174-FALSE
chr272403402CA0.00108EXOC6B-FALSEGA-richSINE,Alu
chr285773494TC0.00099GGCX-TRUEAluYSINE,Alu
chr1610625460TC0.00015EMP2-TRUEAluSxSINE,Alu
chr121100753TC0.00624HP1BP3-TRUEAluJrSINE,Alu
chr286249906TC0.00352LOC90784-TRUEAluJrSINE,Alu

Differential Expression Gene Analysis