Dataset Overview
RBPTARDBP
Knock-MethodshRNA
RBP FamilyRRM_1
Biosample NameK562
Tissue TypeHaematopoietic_and_lymphoid_tissue
Biosample TypeCell line
# of Control2
# of Treat2
SpeciesHuman
Data SourceENCODE
Profile IDENCSR455TNF
PlatformHiSeq
Pubmed ID32252787

TARDBP - Target Gene Network

up-regulated gene   
down-regulated gene   
Gene Type: # of Top Genes:

Differential Expression Genes responding to KD/KO of TARDBP
Gene Mean Expr. of Control Mean Expr. of KD/KO logFC PValue FDR

Function Analysis of Target Genes of TARDBP


Differential Alternative Splicing
  • Exon Skipping
  • Mutually Exclusive Exons
  • Alternative 5’ splice site
  • Alternative 3’ splice site
  • Intron Retention
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot
RBP LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE pValue △Inc Dataset ID Sashimi plot

Differential Variants in RNA (DVRs)
Chrom Site Ref_allele Alt_allele Pvalue Genename Strand KnownRNAediting RepeatName RepeatFamily
chr1145442111CA0.00090NBPF20,NBPF10,TXNIP+FALSE
chr642048128GT0.00604TAF8+FALSEAluSq2SINE,Alu
chr117394775GA0.00103PADI2-FALSE
chr652269046CG0.00338PAQR8+FALSE
chr537291446TC6.87884E-05.FALSEAluSx3SINE,Alu
chr133149363AG0.00237SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1201488143AG0.00492.FALSEAluSzSINE,Alu
chr133139061TC0.00079RBBP4+FALSEAluSx3SINE,Alu
chr128785597GC0.00595PHACTR4+FALSE
chr1233514975GT0.00584MLK4+FALSE
chr110520174TC0.00158.FALSEAluSxSINE,Alu
chr1145291217CT0.00415NBPF20+FALSE
chr1156713558GA8.10199E-06HDGF-FALSE
chr3179042832AG0.00308ZNF639+TRUEAluSpSINE,Alu
chr145244411CA0.00656RPS8+FALSE
chr3113528895AT0.00191ATP6V1A+FALSEAluSpSINE,Alu
chr110520532TC0.00150.FALSEAluSx1SINE,Alu
chr146033497TC0.00719AKR1A1+FALSEAluYk3SINE,Alu
chr3196662641TC0.00059NCBP2-FALSE
chr133149496AG0.00504SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr145975498AG0.00018MMACHC+TRUEAluSx4SINE,Alu
chr2191067764AT0.00165C2orf88+FALSE
chr565120054CT0.00625NLN+FALSE
chr1214529742TC6.22071E-05PTPN14-TRUE
chr3119545349TC0.00805GSK3B-FALSE
chr119984346AG0.00071MINOS1-NBL1,NBL1+FALSE
chr456295160TA0.00187CLOCK-FALSE(T)nSINE,Alu
chr1226589958GA0.00613PARP1-FALSE
chr12303094TC0.00113MORN1-TRUEAluSpSINE,Alu
chr1235383188AG0.00531ARID4B-FALSE
chr633269307TC0.00645.FALSEAluSxSINE,Alu
chrX16781156AG0.00061.FALSEAluJoSINE,Alu
chr116889864CA6.58858E-05NBPF1-FALSE
chr116946336GA0.00409CROCCP2-FALSE
chr154691922TA0.00067SSBP3-FALSE
chr2242176182GA2.43141E-09HDLBP-FALSE
chr1746803538CT0.00492HOXB13-FALSE
chr1089623858GC0.00086PTEN+FALSE(CGG)nSINE,Alu
chr1179045672GA0.00920FAM20B+FALSE
chr717384818AG0.00241AHR+TRUEAluScSINE,Alu
chr286731290TC0.00149CHMP3,RNF103-CHMP3-FALSEL1MC1SINE,Alu
chr342591446AG0.00012SEC22C-FALSE
chr1109535117CT0.00211WDR47-FALSE
chr1183218868TG0.00091NMNAT2-FALSE
chr1475202288CT0.00706FCF1+FALSEAluScSINE,Alu
chr110517659TC0.00012.FALSEAluSx1SINE,Alu
chr1109351501AG0.00921STXBP3+FALSE
chr642047404AG0.00182TAF8+TRUEAluSz6SINE,Alu
chr1150771703TC0.00500CTSK-FALSE
chr111347154AT0.00366UBIAD1+FALSE
chr2152132130AG0.00071NMI-FALSE
chr147905555AC0.00661FOXD2+FALSE
chr16283292TC0.00993ICMT-TRUEAluSx3SINE,Alu
chr286249840TC0.00482LOC90784-TRUEAluJrSINE,Alu
chrX77084038TC0.00265MAGT1-TRUEAluSzSINE,Alu
chr19162348TC0.00359.FALSEAluSxSINE,Alu
chr120977599CG0.00489PINK1,PINK1-AS+,-FALSE
chr110520258TC0.00396.FALSEAluSxSINE,Alu
chr120826083GA0.00289MUL1-FALSE
chr1154323557CT0.00018ATP8B2+FALSE
chr1204526631AG0.00536MDM4+TRUEAluSxSINE,Alu
chr1120612194CG0.00561NOTCH2-FALSE(CCG)nSINE,Alu
chr133149496AG0.00662SYNC,RBBP4+,-FALSEAluSx1SINE,Alu
chr1171501831AG0.00040PRRC2C+FALSE
chr47764148GA2.22190E-11AFAP1,AFAP1-AS1+,-FALSE
chr18413317AC0.00957RERE-FALSE
chr1590820083AG4.07036E-06.FALSEAluYSINE,Alu
chr1173834149AC0.00265GAS5-FALSEAluSzSINE,Alu
chr9130268407CG0.00902FAM129B-FALSE(CTCA)nSINE,Alu
chr1117532790CT0.00981PTGFRN+FALSE
chr261277775AG0.00640PEX13+TRUEAluYSINE,Alu
chr1077807027TC0.00089C10orf11+FALSE
chr10121437033TG0.00357BAG3+FALSE
chr136755235AG0.00562THRAP3+FALSE
chr375475670AC0.00506FAM86DP-FALSE
chr123408016CA4.80633E-05KDM1A+FALSE
chr1453109823TC2.25911E-06ERO1A-TRUEMER53SINE,Alu
chr146032311AG0.00043AKR1A1+FALSE
chr1146495576GC0.00107LOC728989-FALSE
chr1179045500CA0.00043FAM20B+FALSE
chr575469427GA0.00155SV2C+FALSE
chr117733268TC0.00472RCC2-FALSE
chr5149364144AG0.00014SLC26A2+TRUEAluSc8SINE,Alu
chr642857179CA0.00492RPL7L1+FALSEAluSpSINE,Alu
chr1765334868TC0.00096PSMD12-TRUEAluSqSINE,Alu
chr442003671AG0.00535SLC30A9+FALSE
chr1453243434TC0.00421GNPNAT1-TRUEAluSx3SINE,Alu
chr1145512081AG0.00579NBPF20,NBPF10,RBM8A,GNRHR2+,-FALSEAluYSINE,Alu
chr345153708GA4.36430E-08CDCP1-FALSE
chr4128756579AG0.00501.FALSEAluSxSINE,Alu
chr236776053TC0.00029CRIM1+FALSE
chr3196729939CT0.00862MELTF,MFI2-AS1+,-FALSEG-richSINE,Alu
chr3197611106AG0.00137.FALSEAluSx1SINE,Alu
chr237330431TC0.00231.FALSEAluSq2SINE,Alu
chr3194789663TC0.00754XXYLT1-FALSEMARNASINE,Alu
chr146075604AG0.00155NASP+TRUEAluSx4SINE,Alu
chr136024788CT5.60663E-14NCDN+FALSE
chr110519982TC3.22355E-05.FALSEAluJrSINE,Alu
chr720177613TC0.00913MACC1,LOC101927668-TRUEAluSxSINE,Alu
chr2018468633CA3.51877E-10RBBP9-FALSE
chr41006333GA0.00117FGFRL1+FALSE(CTG)nSINE,Alu
chr193804952GA0.00421CCDC18-AS1-FALSE
chr220401856TG0.00265SDC1-FALSE
chr63022544TC0.00440HTATSF1P2-TRUEAluJrSINE,Alu
chr1142688597CT0.00605.FALSE
chr237329352TC0.00403.FALSEAluJr4SINE,Alu
chr145976257CA0.00015MMACHC+FALSE
chr237331065TC0.00527.FALSEAluSx1SINE,Alu
chr1688785189TC0.00636PIEZO1-TRUEAluJrSINE,Alu
chr170718278CG0.00663.FALSE
chr7143003523TG2.48474E-05CASP2+FALSEAluYSINE,Alu
chr452753346AG0.00782DCUN1D4+TRUEAluScSINE,Alu
chr7131241085GA0.00600PODXL-FALSE(GCA)nSINE,Alu
chr2128949342AG0.00397UGGT1+TRUEAluSgSINE,Alu
chr1115313038GA0.00144SIKE1-FALSE
chr532601672AT0.00563SUB1+FALSE
chr128661767AG0.00242MED18+TRUEAluSgSINE,Alu
chr126608012CA0.00564SH3BGRL3+FALSE
chr110520683TC0.00457DFFA-TRUEAluSc8SINE,Alu
chr1913883923AG0.00493MRI1+TRUEAluSzSINE,Alu
chr1176736712AG0.00027ACER3+TRUEAluSzSINE,Alu
chr116927391TC0.00110NBPF1-FALSE
chr1148752615CA0.00042.FALSE
chr29629954TC0.00308ADAM17-FALSE
chr1203711876GA0.00444ATP2B4+FALSE
chr11018144TC0.00019C1orf159-FALSE
chr1144852203TG0.00029NBPF20,PDE4DIP+,-FALSE
chr1142700116CT0.00081ANKRD20A12P-FALSE
chr1753470462CT0.00230MMD-FALSE
chr311598816CA0.00118ATG7,VGLL4+,-FALSE
chr1109465170TC0.00565GPSM2+FALSE
chr42940085TC8.20099E-05NOP14-AS1,NOP14+,-FALSEAluSpSINE,Alu
chr128661656AG0.00026MED18+TRUEAluSgSINE,Alu
chr1424661020CT0.00504TM9SF1-FALSEAluJbSINE,Alu
chr1200522058TA0.00209KIF14-FALSEAluSgSINE,Alu
chr4103183510CT0.00718SLC39A8-FALSE
chr119411087CT0.00226UBR4-FALSE
chr1155230131CT0.00829SCAMP3-FALSE
chr7100957851TC0.00028LOC101927746,IFT22+,-FALSEMADE1SINE,Alu
chr2232319499TA0.00165NCL-FALSE
chr19163393TC0.00327.FALSEAluSpSINE,Alu
chr11419700AG0.00464ATAD3B+TRUEAluYk2SINE,Alu
chr2102484482GA0.00213MAP4K4+FALSE
chr110517314TC0.00802.FALSEAluJrSINE,Alu
chr488814756CT0.00145.FALSE
chr417802819TC0.00112DCAF16-TRUEAluSzSINE,Alu
chr210586904CT0.00041ODC1,SNORA80B-FALSE
chr347628808AT0.00792SMARCC1-FALSE
chr4190864378TG0.00247FRG1+FALSEGA-richSINE,Alu
chr581571669CT0.00143RPS23-FALSE
chr1749042381TC0.00931SPAG9-TRUEAluJbSINE,Alu
chr13545191CT5.51731E-05TPRG1L+FALSE
chr5184393CT0.00228PLEKHG4B+FALSE
chr310192825AG0.00042VHL+TRUEAluSx1SINE,Alu
chr1139233CA0.00653LOC729737-FALSE
chr133148251AG0.00389SYNC,RBBP4+,-FALSEAluSgSINE,Alu
chr1942375586AG0.00404.FALSEAluSxSINE,Alu
chr110521170TC0.00538DFFA-TRUEAluYSINE,Alu
chr2234775941AG0.00161MSL3P1-FALSE
chr9132268359AG0.00436LINC00963+TRUEAluJbSINE,Alu
chr1717425631CT0.00036PEMT-FALSE
chr127202963CT0.00106.FALSEAluSq2SINE,Alu
chr6107113953CG0.00300QRSL1+FALSEAluSgSINE,Alu
chr794060361CT2.02320E-06COL1A2+FALSE
chr3158547143GA0.00178MFSD1+FALSE
chr121671943TG0.00471ECE1-FALSE(GCTCCCG)nSINE,Alu
chr146806550CT0.00105NSUN4+FALSE
chr112058869CT0.00027MFN2+FALSE
chr1757656854CT0.00928DHX40+FALSE
chr362282907CT9.50704E-05PTPRG-AS1-FALSE
chr16159719CT4.79205E-09KCNAB2+FALSE
chr348894565TA0.00142SLC25A20-FALSE
chr970483778AT0.00026CBWD5-FALSE
chr255462102AG0.00026RPS27A+FALSE
chr3181430454GA0.00577SOX2-OT,SOX2+FALSE
chr131732602CA0.00148SNRNP40-FALSE
chr161727060GA0.00922CRAMP1+FALSE
chr1936260451AG0.00854.FALSEAluYSINE,Alu
chr2206987731TC0.00731.FALSEAluJbSINE,Alu
chr126901090CT0.00952RPS6KA1+FALSE
chr144818525TC0.00235ERI3-FALSE
chr1468117864AT0.00744ARG2+FALSE
chr267631831GA0.00423ETAA1+FALSE
chr116893686GC0.00138NBPF1-FALSE
chr224223291AG0.00512UBXN2A+TRUEAluScSINE,Alu
chr129464178GA0.00081LOC642846+FALSE
chr237330172TG0.00972.FALSE
chr1150479901CT0.00228TARS2+FALSEAluSc8SINE,Alu
chr2239972080TA0.00136HDAC4-FALSE
chr114590GA0.00050WASH7P-FALSE
chr5179048585TC0.00150HNRNPH1-FALSE
chr722983600TC0.00025FAM126A-FALSE
chr7120740103GT0.00601CPED1+FALSE
chr2241252612GA0.00561ST13-FALSE
chr12160988GA0.00137SKI+FALSE
chr1347325380GA0.00270LRCH1+FALSE
chr153680090GA0.00321C1orf123-FALSE
chr1110950295CA0.00359LAMTOR5-FALSE
chr1225678910TC2.51322E-05ENAH-TRUEAluSx1SINE,Alu
chr19740896CT0.00078PIK3CD,PIK3CD-AS2+,-FALSEMLT1F1SINE,Alu
chr11345006AG1.26297E-06.FALSEAluSgSINE,Alu
chr16161107AT0.00218KCNAB2+FALSE
chr1179829200TC0.00497TOR1AIP2-TRUEAluJrSINE,Alu
chr1144606996GC0.00107NBPF20+FALSE
chr110521237TC0.00348DFFA-TRUEAluYSINE,Alu
chr119586532AG0.00166MRTO4+TRUEAluSzSINE,Alu
chr5149363219AG0.00866SLC26A2+FALSEAluJrSINE,Alu
chr138423055CA0.00015SF3A3-FALSE
chr3120046117GT0.00443LRRC58-FALSEAluYi6SINE,Alu
chr1144822330CT6.80810E-06NBPF20,NBPF9+FALSE
chr1183218870GT0.00338NMNAT2-FALSE
chr1146650289CT0.00967PDIA3P1+FALSE
chr613788297TC0.00979MCUR1-TRUEAluSxSINE,Alu
chr4190883001CG0.00319FRG1+FALSE
chr139988084GA0.00060BMP8A,PPIEL+,-FALSE
chr2191555984TA0.00171NAB1+FALSE
chr122419433TG0.00200CDC42+FALSE
chr1207942472AG2.11430E-05CD46+TRUEAluSg4SINE,Alu
chr236777209TC0.00299CRIM1+FALSE(TG)nSINE,Alu

Differential Expression Gene Analysis