Dataset Overview
RBP
G3BP2
Knock-Method
shRNA
RBP Family
NTF2
Biosample Name
HepG2
Tissue Type
Liver
Biosample Type
Cell line
# of Control
2
# of Treat
2
Species
Human
Data Source
ENCODE
Profile ID
ENCSR945UYL
Platform
HiSeq
Pubmed ID
32252787
G3BP2 - Target Gene Network
up-regulated gene
down-regulated gene
Gene Type:
the most differential
the most up-regulated
the most down-regulated
# of Top Genes:
25
50
75
100
Differential Expression Genes responding to KD/KO of G3BP2
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Gene
Mean Expr. of Control
Mean Expr. of KD/KO
logFC
PValue
FDR
A1CF
29.02
36.23
0.58956
2.65578E-25
6.16569E-24
A2M
2827.98
2461.73
-0.24753
4.61401E-05
0.00014
AACS
17.52
16.52
-0.17671
0.00568
0.01139
AADAC
0.87
1.82
1.08795
1.36507E-06
5.17415E-06
AADAT
2.45
5.02
0.71358
1.69654E-07
7.29872E-07
AAGAB
4.83
6.29
0.29609
0.00784
0.01528
AAK1
1.2
1.17
0.32635
0.04652
0.07531
AAMP
124.44
125.16
-0.13442
0.02382
0.04152
AARS
51.81
49.69
-0.18845
0.00132
0.00300
AASDHPPT
16.4
14.77
-0.21666
0.00270
0.00580
Showing 1 to 10 of 8,086 entries
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Function Analysis of Target Genes of G3BP2
Set Enrichment Analysis (GSEA)
Gene Ontology(GO) Enrichment
KEGG Pathway Enrichment
Differential Alternative Splicing
Exon Skipping
Mutually Exclusive Exons
Alternative 5’ splice site
Alternative 3’ splice site
Intron Retention
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ABCC2
101576820_101576968_101572774_101572901_101577064_101577241
0.00258
0.313
DataSet_01_325
View details
ABCC2
101576820_101576915_101572774_101572901_101577064_101577156
0.00304
0.334
DataSet_01_325
View details
ABCD3
94946964_94947111_94946019_94946162_94948725_94948795
0.00626
0.048
DataSet_01_325
View details
ACOT9
23752457_23752484_23751288_23751334_23754035_23754133
0.00460
0.276
DataSet_01_325
View details
ADRM1
60883423_60883526_60883038_60883234_60883710_60883918
0.00003
-0.127
DataSet_01_325
View details
AHSA2
61413114_61413216_61412636_61412753_61413580_61413632
0.00002
0.212
DataSet_01_325
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AHSA2
61413151_61413216_61412636_61412753_61413580_61413632
0.00008
0.255
DataSet_01_325
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AK2
33477674_33477723_33476355_33476434_33478807_33479003
0.00263
0.064
DataSet_01_325
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AKAP8L
15509440_15509577_15508524_15508666_15510112_15510221
0.00001
0.134
DataSet_01_325
View details
AKAP8L
15509440_15509514_15508524_15508666_15510112_15510221
0.00008
0.119
DataSet_01_325
View details
Showing 1 to 10 of 217 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC002116.8
36503902_36503991_36504245_36504324_36502305_36502366
0.00290
-0.084
DataSet_01_325
View details
ACADM
76216135_76216231_76226806_76227055_76215103_76215244
0.00004
0.168
DataSet_01_325
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ACLY
40068672_40068795_40069967_40070149_40066474_40066537
0.00020
0.135
DataSet_01_325
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ACP1
272036_272150_272191_272305_271865_271939
0.00006
-0.163
DataSet_01_325
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AFP
74309063_74309161_74313178_74313393_74308012_74308145
0.00001
-0.106
DataSet_01_325
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AHSG
186336079_186336280_186337645_186337863_186334975_186335139
0.00272
-0.115
DataSet_01_325
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AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00580
-0.006
DataSet_01_325
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AHSG
186336079_186336280_186336300_186336426_186334975_186335139
0.00988
-0.085
DataSet_01_325
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ALB
74283804_74284028_74285223_74285356_74283247_74283386
0.00633
-0.119
DataSet_01_325
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APEH
49711921_49712054_49712615_49712742_49711799_49711846
0.00112
-0.2
DataSet_01_325
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Showing 1 to 10 of 90 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
ACAA2
47340125_47340323_47340186_47340323_47329056_47329223
0.00750
0.192
DataSet_01_325
View details
AKAP8L
15509440_15510221_15510112_15510221_15508524_15508666
0.00005
0.116
DataSet_01_325
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APEX1
20923779_20923932_20923779_20923862_20924072_20924260
0.00344
0.032
DataSet_01_325
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C19orf80
11350294_11350610_11350294_11350464_11350810_11350972
0.00002
-0.7
DataSet_01_325
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CNOT1
58590750_58590897_58590765_58590897_58589687_58589812
0.00198
-0.139
DataSet_01_325
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ELL2
95268335_95268417_95268367_95268417_95255127_95255249
0.00041
-0.365
DataSet_01_325
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ENPP3
131995385_131995502_131995385_131995421_131996219_131996329
0.00734
-0.063
DataSet_01_325
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GALT
34646641_34646864_34646641_34646783_34647085_34647255
0.00020
-0.115
DataSet_01_325
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GLTSCR2
48259012_48259244_48259012_48259079_48259784_48259861
0.00012
-0.038
DataSet_01_325
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MYL6
56552467_56553514_56552467_56552495_56553758_56553932
0.00369
0.014
DataSet_01_325
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Showing 1 to 10 of 23 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AC007319.1
188419002_188419120_188419043_188419120_188412199_188412434
0.00008
-0.213
DataSet_01_325
View details
ACTG1
79478213_79478829_79478213_79478652_79478928_79479168
0.00557
0.007
DataSet_01_325
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APRT
88876477_88876643_88876477_88876556_88876830_88876964
0.00470
0.545
DataSet_01_325
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CCNL2
1326145_1328183_1326145_1326245_1328775_1328840
0.00126
0.035
DataSet_01_325
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CNOT11
101874252_101874417_101874299_101874417_101869263_101869940
0.00423
-0.092
DataSet_01_325
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COL27A1
117004396_117004511_117004466_117004511_117002713_117002767
0.00827
0.278
DataSet_01_325
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CTSA
44523461_44523540_44523471_44523540_44523288_44523380
0.00157
0.041
DataSet_01_325
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CUL7
43014248_43014443_43014248_43014339_43014617_43014845
0.00608
0.213
DataSet_01_325
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DHRS2
24110874_24112428_24112360_24112428_24109002_24109104
0.00149
0.065
DataSet_01_325
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DNAJC10
183604271_183605115_183605025_183605115_183600975_183601113
0.00202
0.087
DataSet_01_325
View details
Showing 1 to 10 of 33 entries
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RBP
LongES_LongEE_ShortES_ShortEE_FlankingES_FlankingEE
pValue
△Inc
Dataset ID
Sashimi plot
AAMP
219130301_219130669_219130301_219130405_219130553_219130669
0.00517
0.063
DataSet_01_325
View details
ACTB
5567911_5569031_5567911_5568350_5568791_5569031
0.00071
0.011
DataSet_01_325
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ACTB
5568791_5569294_5568791_5569031_5569165_5569294
0.00696
0.01
DataSet_01_325
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ACTB
5567634_5568350_5567634_5567816_5567911_5568350
0.00987
0.007
DataSet_01_325
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AKAP8L
15514285_15514526_15514285_15514366_15514468_15514526
0.00208
-0.163
DataSet_01_325
View details
ANAPC5
121783641_121784808_121783641_121783834_121784698_121784808
0.00203
0.128
DataSet_01_325
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ANAPC5
121764898_121766300_121764898_121765034_121766118_121766300
0.00424
0.125
DataSet_01_325
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APEX1
20923736_20924260_20923736_20923862_20924072_20924260
0.00031
0.059
DataSet_01_325
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ASXL1
31015930_31016225_31015930_31016051_31016127_31016225
0.00188
0.077
DataSet_01_325
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ATF4
39916568_39917676_39916568_39916756_39917358_39917676
0.00000
0.077
DataSet_01_325
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Differential Variants in RNA (DVRs)
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Chrom
Site
Ref_allele
Alt_allele
Pvalue
Genename
Strand
KnownRNAediting
RepeatName
RepeatFamily
chr1
27992799
T
A
0.00017
IFI6
-
FALSE
FAM
SINE,Alu
chr1
36531942
A
G
0.00042
.
FALSE
AluSq2
SINE,Alu
chr1
203277245
G
A
0.00115
BTG2
+
FALSE
chr1
145511988
A
G
0.00965
NBPF20,NBPF10,RBM8A,GNRHR2
+,-
FALSE
AluY
SINE,Alu
chr1
144828795
C
G
0.00887
NBPF20,NBPF9
+
FALSE
chr1
93297590
C
A
0.00325
.
FALSE
chr1
10518821
T
C
0.00277
.
FALSE
AluSx1
SINE,Alu
chr1
10517352
T
C
0.00050
.
FALSE
AluJr
SINE,Alu
chr1
109856085
G
A
0.00684
SORT1
-
FALSE
chr1
92946618
A
G
0.00062
GFI1
-
FALSE
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Differential Expression Gene Analysis
Heatmap of Unsupervised Hierarchical Clustering
Scatter Diagram of Differential Expression